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IE832631L - Derivatives of 2-piperazinopyrimidine. - Google Patents

Derivatives of 2-piperazinopyrimidine.

Info

Publication number
IE832631L
IE832631L IE840561A IE263183A IE832631L IE 832631 L IE832631 L IE 832631L IE 840561 A IE840561 A IE 840561A IE 263183 A IE263183 A IE 263183A IE 832631 L IE832631 L IE 832631L
Authority
IE
Ireland
Prior art keywords
piperazinyl
pyrimidine
piperazinopyrimidine
derivatives
acid
Prior art date
Application number
IE840561A
Other versions
IE56184B1 (en
Inventor
Crisafulli Emilio
Frigerio Marco
Chambon Jeanpierre
Original Assignee
Manta Systems Remote Control L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manta Systems Remote Control L filed Critical Manta Systems Remote Control L
Publication of IE832631L publication Critical patent/IE832631L/en
Publication of IE56184B1 publication Critical patent/IE56184B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/10—Succinic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/145—Maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255—Tartaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Claims (for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE) An acid addition salt of 2-(1-piperazinyl)pyrimidine with a dicarboxylic acid. 1. Claims (for the contracting state : AT) A process for preparing acid salts of 2-(1-piperazinyl)pyrimidine with dicarboxylic acids, characterized in that it comprises reacting 2-(1-piperazinyl)-pyrimidine with the calculated quantity of a dicarboxylic acid in an organic or aqueous organic solvent.
IE2631/83A 1982-11-12 1983-11-11 Acid addition salts of 2-piperazinopyrimidine,process for their preparation and pharmaceutical compositions containing them IE56184B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8218975A FR2536071B1 (en) 1982-11-12 1982-11-12 2-PIPERAZINOPYRIMIDINE ACID SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Publications (2)

Publication Number Publication Date
IE832631L true IE832631L (en) 1984-05-12
IE56184B1 IE56184B1 (en) 1991-05-08

Family

ID=9279123

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2631/83A IE56184B1 (en) 1982-11-12 1983-11-11 Acid addition salts of 2-piperazinopyrimidine,process for their preparation and pharmaceutical compositions containing them

Country Status (10)

Country Link
EP (1) EP0109340B1 (en)
JP (1) JPS59144766A (en)
AT (1) ATE19243T1 (en)
AU (1) AU567311B2 (en)
CA (1) CA1249275A (en)
DE (1) DE3363093D1 (en)
FR (1) FR2536071B1 (en)
IE (1) IE56184B1 (en)
NZ (1) NZ206222A (en)
ZA (1) ZA838423B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959368A (en) * 1986-02-24 1990-09-25 Mitsui Petrochemical Industries Ltd. Therapeutic agent for neurological diseases
JP2561689B2 (en) * 1986-02-24 1996-12-11 三井石油化学工業株式会社 Neurological drug
YU39503A (en) * 2000-11-22 2006-05-25 F. Hoffmann-La Roche Ag. Pyrimidine derivatives
AR038368A1 (en) 2002-02-01 2005-01-12 Novartis Ag N-PYRIMIDIN-2-IL-AMINAS SUBSTITUTED COMPOUNDS AS IGE INHIBITORS, A PHARMACEUTICAL COMPOSITION AND THE USE OF SUCH COMPOUNDS FOR THE PREPARATION OF A MEDICINAL PRODUCT
JP4726622B2 (en) * 2005-12-14 2011-07-20 三洋電機株式会社 Leaded battery

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US985657A (en) * 1910-12-10 1911-02-28 Baldwin Locomotive Works Car-truck.
US2985657A (en) * 1959-10-12 1961-05-23 Paul A J Janssen 1-(aroylalkyl)-4-heterocyclylpiperazines
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
DE3321969A1 (en) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-PYRIMIDINYL-1-PIPERAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME

Also Published As

Publication number Publication date
CA1249275A (en) 1989-01-24
DE3363093D1 (en) 1986-05-22
FR2536071B1 (en) 1986-07-11
AU567311B2 (en) 1987-11-19
ATE19243T1 (en) 1986-05-15
ZA838423B (en) 1984-06-27
IE56184B1 (en) 1991-05-08
NZ206222A (en) 1985-09-13
EP0109340A2 (en) 1984-05-23
EP0109340B1 (en) 1986-04-16
AU2116483A (en) 1984-05-17
EP0109340A3 (en) 1984-06-27
FR2536071A1 (en) 1984-05-18
JPS59144766A (en) 1984-08-18

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