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IE810989L - Theophylline tablet - Google Patents

Theophylline tablet

Info

Publication number
IE810989L
IE810989L IE810989A IE98981A IE810989L IE 810989 L IE810989 L IE 810989L IE 810989 A IE810989 A IE 810989A IE 98981 A IE98981 A IE 98981A IE 810989 L IE810989 L IE 810989L
Authority
IE
Ireland
Prior art keywords
theophylline
tableting
ingestion
excipients
maintenance
Prior art date
Application number
IE810989A
Other languages
Unknown language ( )
Other versions
IE51157B1 (en
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IE810989L publication Critical patent/IE810989L/en
Publication of IE51157B1 publication Critical patent/IE51157B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Non-disintegrating tablets containing at least 95% by weight theophylline having a pair of opposing substantially planar surfaces and a very thin cross-section (i.e. 2.03-3.05 mm) have a high bioavailability on ingestion and a relatively steady release rate permitting a 12 hr. dosing interval for maintenance of non-toxic therapeutic blood theophylline concentrations. Excipients or tableting aids are not required, but trace amounts of a tableting lubricant are preferably included to facilitate continuous large scale production.
IE989/81A 1980-05-06 1981-05-05 Sustained release theophylline tablet having reduced bulk IE51157B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14742980A 1980-05-06 1980-05-06
US24978781A 1981-04-01 1981-04-01

Publications (2)

Publication Number Publication Date
IE810989L true IE810989L (en) 1981-11-06
IE51157B1 IE51157B1 (en) 1986-10-15

Family

ID=26844921

Family Applications (1)

Application Number Title Priority Date Filing Date
IE989/81A IE51157B1 (en) 1980-05-06 1981-05-05 Sustained release theophylline tablet having reduced bulk

Country Status (17)

Country Link
AT (1) AT380789B (en)
AU (1) AU549299B2 (en)
CA (1) CA1165241A (en)
CY (1) CY1368A (en)
DE (1) DE3117756A1 (en)
DK (1) DK155976C (en)
FI (1) FI811356A7 (en)
FR (1) FR2484253A1 (en)
GB (1) GB2078518B (en)
HK (1) HK4288A (en)
IE (1) IE51157B1 (en)
IT (1) IT1209867B (en)
KE (1) KE3722A (en)
LU (1) LU83342A1 (en)
NL (1) NL8102168A (en)
SE (1) SE452550B (en)
SG (1) SG30987G (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4547358A (en) * 1980-05-06 1985-10-15 Mead Johnson & Company Sustained release tablet containing at least 95 percent theophylline
US4503031A (en) * 1982-12-17 1985-03-05 Glassman Jacob A Super-fast-starting-sustained release tablet
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
US4753945A (en) * 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
FR2595945B1 (en) * 1986-03-19 1990-01-19 Doms Laboratoires THEOPHYLLIN DELAY TABLET BASED ON P.V.C., AND PROCESS FOR PREPARING THE SAME
USD557612S1 (en) * 2006-04-10 2007-12-18 Parfums Christian Dior Flask for a cosmetic product

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297088A (en) * 1961-01-31
DE1228029C2 (en) * 1964-05-09 1973-05-17 Merck Ag E Process for the production of tablets by pressing powder mixtures without prior granulation
US3723614A (en) * 1971-01-06 1973-03-27 Ciba Geigy Ag Maltese-cross scored tablet
US4264573A (en) * 1979-05-21 1981-04-28 Rowell Laboratories, Inc. Pharmaceutical formulation for slow release via controlled surface erosion

Also Published As

Publication number Publication date
CY1368A (en) 1987-08-07
GB2078518A (en) 1982-01-13
IE51157B1 (en) 1986-10-15
LU83342A1 (en) 1982-01-20
FR2484253A1 (en) 1981-12-18
KE3722A (en) 1987-04-30
AU7020581A (en) 1981-11-12
DK200181A (en) 1981-11-07
FI811356L (en) 1981-11-07
IT1209867B (en) 1989-08-30
HK4288A (en) 1988-01-29
DE3117756C2 (en) 1992-11-26
DE3117756A1 (en) 1982-04-29
SE452550B (en) 1987-12-07
DK155976B (en) 1989-06-12
AT380789B (en) 1986-07-10
GB2078518B (en) 1984-04-11
ATA202081A (en) 1985-12-15
FI811356A7 (en) 1981-11-07
CA1165241A (en) 1984-04-10
FR2484253B1 (en) 1983-06-03
SE8102814L (en) 1981-11-07
IT8148406A0 (en) 1981-05-06
AU549299B2 (en) 1986-01-23
NL8102168A (en) 1981-12-01
DK155976C (en) 1989-10-30
SG30987G (en) 1987-07-17

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Legal Events

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MK9A Patent expired