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ES8203086A1 - 4-Methoxy-isophthalic Acid Picolylemide Monohydrate - Google Patents

4-Methoxy-isophthalic Acid Picolylemide Monohydrate

Info

Publication number
ES8203086A1
ES8203086A1 ES501470A ES501470A ES8203086A1 ES 8203086 A1 ES8203086 A1 ES 8203086A1 ES 501470 A ES501470 A ES 501470A ES 501470 A ES501470 A ES 501470A ES 8203086 A1 ES8203086 A1 ES 8203086A1
Authority
ES
Spain
Prior art keywords
monohydrate
methoxy
picolylemide
isophthalic acid
picolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES501470A
Other languages
Spanish (es)
Other versions
ES501470A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Manetti & Roberts Italo Brit
Original Assignee
Manetti & Roberts Italo Brit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manetti & Roberts Italo Brit filed Critical Manetti & Roberts Italo Brit
Publication of ES8203086A1 publication Critical patent/ES8203086A1/en
Publication of ES501470A0 publication Critical patent/ES501470A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

N,N'-bis-(3-picolyl)-4-methoxy- isophthalamide provided in crystalline form as its monohydrate, is a stable chemical structure and shows a high pharmaceutical activity for the treatment of thromboembolic disorders.
ES501470A 1980-04-23 1981-04-20 A PROCEDURE FOR THE PRODUCTION OF N, N'-BIS- (3-PICOLIL) -4-METOXI-ISOFTALAMIDA MONOHIDRATADA Granted ES501470A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48494/80A IT1143942B (en) 1980-04-23 1980-04-23 PICOLYLAMIDE HYDRATED ISOPHTHALIC ACID WITH ANTI-AGGREGATING, ANTI-THROMBINIC AND ANTI-AGULANT PLASTIC ACTION AND PROCEDURE FOR ITS PREPARATION

Publications (2)

Publication Number Publication Date
ES8203086A1 true ES8203086A1 (en) 1982-02-16
ES501470A0 ES501470A0 (en) 1982-02-16

Family

ID=11266904

Family Applications (1)

Application Number Title Priority Date Filing Date
ES501470A Granted ES501470A0 (en) 1980-04-23 1981-04-20 A PROCEDURE FOR THE PRODUCTION OF N, N'-BIS- (3-PICOLIL) -4-METOXI-ISOFTALAMIDA MONOHIDRATADA

Country Status (23)

Country Link
JP (1) JPS6043063B2 (en)
AT (1) AT375645B (en)
AU (1) AU537921B2 (en)
BE (1) BE888528A (en)
CA (1) CA1129419A (en)
CH (1) CH649533A5 (en)
DD (1) DD158397A5 (en)
DE (1) DE3113150C2 (en)
DK (1) DK155735C (en)
ES (1) ES501470A0 (en)
FI (1) FI74951C (en)
FR (1) FR2481283B1 (en)
GB (1) GB2080288B (en)
IE (1) IE51218B1 (en)
IL (1) IL62509A (en)
IT (1) IT1143942B (en)
NL (1) NL186860C (en)
NO (1) NO154193C (en)
NZ (1) NZ196677A (en)
OA (1) OA06795A (en)
PT (1) PT72899B (en)
SE (1) SE438674B (en)
ZA (1) ZA812362B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1214915B (en) * 1985-10-10 1990-01-31 Manetti & Roberts Italo Brit 4-METHOXYISOPHTALIC ACID DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY IN THROMBOEMBOLIC DISORDERS AND PROCEDURE FOR ITS PREPARATION
US5227492A (en) * 1988-01-20 1993-07-13 Yamanouchi Pharmaceutical Co., Ltd. Diurea derivatives useful as medicaments and processes for the preparation thereof
AR066696A1 (en) * 2007-05-21 2009-09-09 Dybly Ag PICOTAMIDE SALTS. PHARMACEUTICAL COMPOSITIONS.
CN111154113A (en) * 2019-12-31 2020-05-15 肇庆学院 Metal organic complex based on binuclear cobalt (II) and preparation method thereof
CN111154114A (en) * 2019-12-31 2020-05-15 肇庆学院 Zinc (II) metal organic coordination compound based on 5-ethoxy isophthalic acid and preparation method thereof
CN112159347B (en) * 2020-10-27 2022-06-07 常州工程职业技术学院 The preparation method of picotamide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL149810B (en) * 1969-04-21 1976-06-15 Lilly Co Eli METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION BY CONTAINING CRYSTALLINE CEPHALEXIN IN A FORM SUITABLE FOR THERAPEUTIC ADMINISTRATION, FORMED PHARMACEUTICAL PREPARATIONS, AND METHOD OF PREPARING THE APPLICATION FOR THE EXISTING ABOVE.
IT1016005B (en) * 1970-07-01 1977-05-30 Manetti & Roberts Italo Brit PICOLYLAMIDES OF ISOPHTHALIC ACID 4 HYDROXIS AND ITS DERIVATIVES AND RELATIVE PREPARATION PROCEDURE
US3973026A (en) * 1975-02-05 1976-08-03 Societa Italo-Britannica L. Manetti-H. Roberts & C. Inhibitor of blood plate aggregation

Also Published As

Publication number Publication date
IT1143942B (en) 1986-10-29
JPS5735566A (en) 1982-02-26
AU6931081A (en) 1981-10-29
IT8048494A0 (en) 1980-04-23
SE438674B (en) 1985-04-29
IE51218B1 (en) 1986-11-12
IL62509A (en) 1984-03-30
PT72899A (en) 1981-05-01
DE3113150A1 (en) 1982-01-28
BE888528A (en) 1981-08-17
FR2481283A1 (en) 1981-10-30
ATA166481A (en) 1984-01-15
AT375645B (en) 1984-08-27
FI811257L (en) 1981-10-24
NL186860C (en) 1991-03-18
DK177281A (en) 1981-10-24
GB2080288A (en) 1982-02-03
FR2481283B1 (en) 1985-01-04
CH649533A5 (en) 1985-05-31
IE810808L (en) 1981-10-23
CA1129419A (en) 1982-08-10
PT72899B (en) 1982-04-05
SE8101963L (en) 1981-10-24
NO154193B (en) 1986-04-28
NO154193C (en) 1986-08-06
DE3113150C2 (en) 1985-05-15
OA06795A (en) 1982-12-31
DK155735B (en) 1989-05-08
DK155735C (en) 1989-10-02
FI74951B (en) 1987-12-31
NL8102016A (en) 1981-11-16
NZ196677A (en) 1983-05-31
NO811360L (en) 1981-10-26
JPS6043063B2 (en) 1985-09-26
AU537921B2 (en) 1984-07-19
DD158397A5 (en) 1983-01-12
IL62509A0 (en) 1981-05-20
NL186860B (en) 1990-10-16
FI74951C (en) 1988-04-11
ES501470A0 (en) 1982-02-16
ZA812362B (en) 1982-04-28
GB2080288B (en) 1984-02-01

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ES8203086A1 (en) 4-Methoxy-isophthalic Acid Picolylemide Monohydrate
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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010301