IE39410B1 - Anesthetic compositions and their use - Google Patents
Anesthetic compositions and their useInfo
- Publication number
- IE39410B1 IE39410B1 IE1211/74A IE121174A IE39410B1 IE 39410 B1 IE39410 B1 IE 39410B1 IE 1211/74 A IE1211/74 A IE 1211/74A IE 121174 A IE121174 A IE 121174A IE 39410 B1 IE39410 B1 IE 39410B1
- Authority
- IE
- Ireland
- Prior art keywords
- anesthetic compositions
- desoxytetrodotoxin
- tetrodotoxin
- micrograms
- amount
- Prior art date
Links
- 230000003444 anaesthetic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- COVOMQKTVSVWBZ-CJCGOCGYSA-N deoxytetrodotoxin Chemical compound O1C(C2(O)CO)(O)OC3C(O)C1[C@@H]1CN=C(N)NC12C3O COVOMQKTVSVWBZ-CJCGOCGYSA-N 0.000 abstract 2
- CFMYXEVWODSLAX-QOZOJKKESA-N tetrodotoxin Chemical compound O([C@@]([C@H]1O)(O)O[C@H]2[C@@]3(O)CO)[C@H]3[C@@H](O)[C@]11[C@H]2[C@@H](O)N=C(N)N1 CFMYXEVWODSLAX-QOZOJKKESA-N 0.000 abstract 2
- 229950010357 tetrodotoxin Drugs 0.000 abstract 2
- CFMYXEVWODSLAX-UHFFFAOYSA-N tetrodotoxin Natural products C12C(O)NC(=N)NC2(C2O)C(O)C3C(CO)(O)C1OC2(O)O3 CFMYXEVWODSLAX-UHFFFAOYSA-N 0.000 abstract 2
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US388147A US3898339A (en) | 1973-08-14 | 1973-08-14 | Spinal anesthesia using small amounts of tetrodotoxin or desoxytetrodotoxin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE39410L IE39410L (en) | 1975-02-14 |
| IE39410B1 true IE39410B1 (en) | 1978-09-27 |
Family
ID=23532901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1211/74A IE39410B1 (en) | 1973-08-14 | 1974-06-10 | Anesthetic compositions and their use |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3898339A (fr) |
| JP (1) | JPS5048112A (fr) |
| AT (1) | AT335616B (fr) |
| BE (1) | BE816214A (fr) |
| CA (1) | CA1027863A (fr) |
| DD (1) | DD115035A5 (fr) |
| DE (1) | DE2427732A1 (fr) |
| ES (1) | ES427164A1 (fr) |
| FR (1) | FR2240735B1 (fr) |
| GB (1) | GB1453343A (fr) |
| IE (1) | IE39410B1 (fr) |
| LU (1) | LU70304A1 (fr) |
| NL (1) | NL7407853A (fr) |
| ZA (1) | ZA743765B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0750909B1 (fr) * | 1994-03-17 | 2002-12-11 | Nanning Maple Leaf Pharmaceutical Co., Ltd. | Application de composes de quinazoline amino-hydrogenes et de leurs derives au sevrage des toxicomanes |
| CN1051706C (zh) * | 1994-03-17 | 2000-04-26 | 南宁枫叶药业有限公司 | 氨基氢化喹唑啉类化合物及其衍生物戒降药物依赖性的新用途 |
| US5585398A (en) * | 1994-07-15 | 1996-12-17 | Ernst; Amy A. | Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use |
| US5550049A (en) | 1994-11-10 | 1996-08-27 | Merck & Co., Inc | Process for identifying para cation channel modulators |
| WO1998043619A2 (fr) * | 1997-04-02 | 1998-10-08 | The Regents Of The University Of California | Procede d'anesthesie |
| CN1236773C (zh) * | 2000-11-22 | 2006-01-18 | 南宁枫叶药业有限公司 | 用于镇痛、麻醉或治疗药物依赖性的制剂 |
| JP2008513528A (ja) * | 2004-09-22 | 2008-05-01 | ウェックス ファーマシューティカルズ インコーポレイテッド | 末梢神経由来の神経障害性疼痛の治療用テトロドトキシンおよびその誘導体 |
| WO2007025213A2 (fr) * | 2005-08-25 | 2007-03-01 | Wex Pharmaceuticals, Inc. | Utilisation de bloqueurs des canaux sodiques pour gerer les douleurs musculo-squelettiques |
| CA2647235C (fr) | 2006-03-27 | 2019-03-12 | Wex Pharmaceuticals Inc. | Utilisation d'inhibiteurs des canaux sodiques pour traiter la douleur neuropathique consecutive a une chimiotherapie |
-
1973
- 1973-08-14 US US388147A patent/US3898339A/en not_active Expired - Lifetime
-
1974
- 1974-06-08 DE DE19742427732 patent/DE2427732A1/de active Pending
- 1974-06-10 IE IE1211/74A patent/IE39410B1/xx unknown
- 1974-06-11 FR FR7420219A patent/FR2240735B1/fr not_active Expired
- 1974-06-11 ES ES427164A patent/ES427164A1/es not_active Expired
- 1974-06-12 BE BE145320A patent/BE816214A/fr unknown
- 1974-06-12 CA CA202,294A patent/CA1027863A/fr not_active Expired
- 1974-06-12 DD DD179117A patent/DD115035A5/xx unknown
- 1974-06-12 JP JP49067020A patent/JPS5048112A/ja active Pending
- 1974-06-12 AT AT484974A patent/AT335616B/de not_active IP Right Cessation
- 1974-06-12 LU LU70304A patent/LU70304A1/xx unknown
- 1974-06-12 ZA ZA00743765A patent/ZA743765B/xx unknown
- 1974-06-12 NL NL7407853A patent/NL7407853A/xx unknown
- 1974-06-12 GB GB2609474A patent/GB1453343A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5048112A (fr) | 1975-04-30 |
| AT335616B (de) | 1977-03-25 |
| NL7407853A (nl) | 1975-02-18 |
| DE2427732A1 (de) | 1975-02-27 |
| US3898339A (en) | 1975-08-05 |
| ATA484974A (de) | 1976-07-15 |
| BE816214A (fr) | 1974-12-12 |
| CA1027863A (fr) | 1978-03-14 |
| FR2240735A1 (fr) | 1975-03-14 |
| IE39410L (en) | 1975-02-14 |
| FR2240735B1 (fr) | 1978-07-28 |
| LU70304A1 (fr) | 1976-04-13 |
| ZA743765B (en) | 1975-06-25 |
| DD115035A5 (fr) | 1975-09-12 |
| ES427164A1 (es) | 1976-10-01 |
| GB1453343A (en) | 1976-10-20 |
| AU6993474A (en) | 1975-12-11 |
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