ES427164A1 - Un procedimiento para la preparacion de un agente para la anastesia espinal. - Google Patents
Un procedimiento para la preparacion de un agente para la anastesia espinal.Info
- Publication number
- ES427164A1 ES427164A1 ES427164A ES427164A ES427164A1 ES 427164 A1 ES427164 A1 ES 427164A1 ES 427164 A ES427164 A ES 427164A ES 427164 A ES427164 A ES 427164A ES 427164 A1 ES427164 A1 ES 427164A1
- Authority
- ES
- Spain
- Prior art keywords
- desoxytetrodotoxin
- tetrodotoxin
- small amounts
- spinal anesthesia
- micrograms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- COVOMQKTVSVWBZ-CJCGOCGYSA-N deoxytetrodotoxin Chemical compound O1C(C2(O)CO)(O)OC3C(O)C1[C@@H]1CN=C(N)NC12C3O COVOMQKTVSVWBZ-CJCGOCGYSA-N 0.000 title abstract 3
- CFMYXEVWODSLAX-QOZOJKKESA-N tetrodotoxin Chemical compound O([C@@]([C@H]1O)(O)O[C@H]2[C@@]3(O)CO)[C@H]3[C@@H](O)[C@]11[C@H]2[C@@H](O)N=C(N)N1 CFMYXEVWODSLAX-QOZOJKKESA-N 0.000 title abstract 3
- 229950010357 tetrodotoxin Drugs 0.000 title abstract 3
- CFMYXEVWODSLAX-UHFFFAOYSA-N tetrodotoxin Natural products C12C(O)NC(=N)NC2(C2O)C(O)C3C(CO)(O)C1OC2(O)O3 CFMYXEVWODSLAX-UHFFFAOYSA-N 0.000 title abstract 3
- 238000002693 spinal anesthesia Methods 0.000 title 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US388147A US3898339A (en) | 1973-08-14 | 1973-08-14 | Spinal anesthesia using small amounts of tetrodotoxin or desoxytetrodotoxin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES427164A1 true ES427164A1 (es) | 1976-10-01 |
Family
ID=23532901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES427164A Expired ES427164A1 (es) | 1973-08-14 | 1974-06-11 | Un procedimiento para la preparacion de un agente para la anastesia espinal. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3898339A (es) |
| JP (1) | JPS5048112A (es) |
| AT (1) | AT335616B (es) |
| BE (1) | BE816214A (es) |
| CA (1) | CA1027863A (es) |
| DD (1) | DD115035A5 (es) |
| DE (1) | DE2427732A1 (es) |
| ES (1) | ES427164A1 (es) |
| FR (1) | FR2240735B1 (es) |
| GB (1) | GB1453343A (es) |
| IE (1) | IE39410B1 (es) |
| LU (1) | LU70304A1 (es) |
| NL (1) | NL7407853A (es) |
| ZA (1) | ZA743765B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0750909B1 (en) * | 1994-03-17 | 2002-12-11 | Nanning Maple Leaf Pharmaceutical Co., Ltd. | The use of amino hydrogenated quinazoline compounds and derivatives thereof for abstaining from drug dependence |
| CN1051706C (zh) * | 1994-03-17 | 2000-04-26 | 南宁枫叶药业有限公司 | 氨基氢化喹唑啉类化合物及其衍生物戒降药物依赖性的新用途 |
| US5585398A (en) * | 1994-07-15 | 1996-12-17 | Ernst; Amy A. | Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use |
| US5550049A (en) | 1994-11-10 | 1996-08-27 | Merck & Co., Inc | Process for identifying para cation channel modulators |
| WO1998043619A2 (en) * | 1997-04-02 | 1998-10-08 | The Regents Of The University Of California | Method of local anesthesia |
| CN1236773C (zh) * | 2000-11-22 | 2006-01-18 | 南宁枫叶药业有限公司 | 用于镇痛、麻醉或治疗药物依赖性的制剂 |
| JP2008513528A (ja) * | 2004-09-22 | 2008-05-01 | ウェックス ファーマシューティカルズ インコーポレイテッド | 末梢神経由来の神経障害性疼痛の治療用テトロドトキシンおよびその誘導体 |
| WO2007025213A2 (en) * | 2005-08-25 | 2007-03-01 | Wex Pharmaceuticals, Inc. | Use of sodium channel blockers for the management of musculoskeletal pain |
| CA2647235C (en) | 2006-03-27 | 2019-03-12 | Wex Pharmaceuticals Inc. | Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy |
-
1973
- 1973-08-14 US US388147A patent/US3898339A/en not_active Expired - Lifetime
-
1974
- 1974-06-08 DE DE19742427732 patent/DE2427732A1/de active Pending
- 1974-06-10 IE IE1211/74A patent/IE39410B1/xx unknown
- 1974-06-11 FR FR7420219A patent/FR2240735B1/fr not_active Expired
- 1974-06-11 ES ES427164A patent/ES427164A1/es not_active Expired
- 1974-06-12 BE BE145320A patent/BE816214A/xx unknown
- 1974-06-12 CA CA202,294A patent/CA1027863A/en not_active Expired
- 1974-06-12 DD DD179117A patent/DD115035A5/xx unknown
- 1974-06-12 JP JP49067020A patent/JPS5048112A/ja active Pending
- 1974-06-12 AT AT484974A patent/AT335616B/de not_active IP Right Cessation
- 1974-06-12 LU LU70304A patent/LU70304A1/xx unknown
- 1974-06-12 ZA ZA00743765A patent/ZA743765B/xx unknown
- 1974-06-12 NL NL7407853A patent/NL7407853A/xx unknown
- 1974-06-12 GB GB2609474A patent/GB1453343A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5048112A (es) | 1975-04-30 |
| AT335616B (de) | 1977-03-25 |
| IE39410B1 (en) | 1978-09-27 |
| NL7407853A (nl) | 1975-02-18 |
| DE2427732A1 (de) | 1975-02-27 |
| US3898339A (en) | 1975-08-05 |
| ATA484974A (de) | 1976-07-15 |
| BE816214A (fr) | 1974-12-12 |
| CA1027863A (en) | 1978-03-14 |
| FR2240735A1 (es) | 1975-03-14 |
| IE39410L (en) | 1975-02-14 |
| FR2240735B1 (es) | 1978-07-28 |
| LU70304A1 (es) | 1976-04-13 |
| ZA743765B (en) | 1975-06-25 |
| DD115035A5 (es) | 1975-09-12 |
| GB1453343A (en) | 1976-10-20 |
| AU6993474A (en) | 1975-12-11 |
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| USD234560S (en) | Table | |
| USD227603S (en) | Font of characters | |
| USD237025S (en) | Footstool | |
| USD193158S (en) | Combined packaging and serving container | |
| GB1433845A (en) | Phar |