IE34275B1 - Alpha-hydrazino acids - Google Patents
Alpha-hydrazino acidsInfo
- Publication number
- IE34275B1 IE34275B1 IE746/70A IE74670A IE34275B1 IE 34275 B1 IE34275 B1 IE 34275B1 IE 746/70 A IE746/70 A IE 746/70A IE 74670 A IE74670 A IE 74670A IE 34275 B1 IE34275 B1 IE 34275B1
- Authority
- IE
- Ireland
- Prior art keywords
- compositions
- isomer
- june
- alpha
- hydrazino
- Prior art date
Links
- 230000001387 anti-histamine Effects 0.000 abstract 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 abstract 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 235000019260 propionic acid Nutrition 0.000 abstract 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,261,660. Antihistaminic &c compositions. MERCK & CO. Inc. 15 June, 1970 [18 June, 1969; 23 March, 1970], No. 28940/70. Heading A5B. [Also in Division C2] Pharmaceutical compositions having decarboxylase-inhibiting and anti-histaminic activity comprise an L-α-hydrazino-α-R-#-(3, 4-dihydroxyphenyl) propionic acid (in which R is H or C 1-5 alkyl) substantially free of the D-isomer (i.e. containing less than 10% of D-isomer), or a C 1-5 alkyl ester thereof, or a pharmaceutically acceptable salt of said acid or ester, together with a pharmaceutical diluent or carrier. The active ingredient may be used in conjunction with L-dopa. The compositions may be administered orally or parenterally.
[GB1261660A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83530769A | 1969-06-18 | 1969-06-18 | |
| US2207670A | 1970-03-23 | 1970-03-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE34275L IE34275L (en) | 1970-12-18 |
| IE34275B1 true IE34275B1 (en) | 1975-03-19 |
Family
ID=26695471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE746/70A IE34275B1 (en) | 1969-06-18 | 1970-06-09 | Alpha-hydrazino acids |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE752108A (en) |
| CY (1) | CY710A (en) |
| DE (1) | DE2029823C3 (en) |
| FR (1) | FR2052983B1 (en) |
| GB (1) | GB1261660A (en) |
| IE (1) | IE34275B1 (en) |
| IL (1) | IL34687A (en) |
| MY (1) | MY7300470A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5852219A (en) * | 1981-09-22 | 1983-03-28 | Sumitomo Chem Co Ltd | Remedy for parkinson's disease (perkinsonism) |
| EP1321169A1 (en) * | 2001-12-18 | 2003-06-25 | Biofrontera Pharmaceuticals AG | Combination of a serotonin receptor antagonist with a histidine decarboxylase inhibitor as a medicament |
| AU2003293423A1 (en) | 2002-12-06 | 2004-06-30 | Xenoport, Inc. | Carbidopa prodrugs and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1459728A (en) * | 1960-07-22 | 1966-06-17 | Merck & Co Inc | New alpha-hydrazino acids |
-
1970
- 1970-06-09 IE IE746/70A patent/IE34275B1/en unknown
- 1970-06-09 IL IL34687A patent/IL34687A/en unknown
- 1970-06-15 GB GB28940/70A patent/GB1261660A/en not_active Expired
- 1970-06-16 DE DE2029823A patent/DE2029823C3/en not_active Expired
- 1970-06-17 BE BE752108D patent/BE752108A/en not_active IP Right Cessation
- 1970-06-17 FR FR707022243A patent/FR2052983B1/fr not_active Expired
-
1973
- 1973-10-10 CY CY71073A patent/CY710A/en unknown
- 1973-12-30 MY MY470/73A patent/MY7300470A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2029823B2 (en) | 1973-07-26 |
| FR2052983B1 (en) | 1973-07-13 |
| BE752108A (en) | 1970-12-17 |
| DE2029823C3 (en) | 1974-04-11 |
| MY7300470A (en) | 1973-12-31 |
| CY710A (en) | 1973-10-10 |
| IE34275L (en) | 1970-12-18 |
| DE2029823A1 (en) | 1971-12-30 |
| FR2052983A1 (en) | 1971-04-16 |
| IL34687A (en) | 1973-07-30 |
| GB1261660A (en) | 1972-01-26 |
| IL34687A0 (en) | 1970-08-19 |
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