HUS2100038I1 - Anti-CD20 antitest készítmények - Google Patents

Anti-CD20 antitest készítmények

Info

Publication number: HUS2100038I1
Authority: HU; Hungary
Prior art keywords: antibody preparations; preparations; antibody
Prior art date: 2007-07-06

Application number

HUS2100038C

Other languages

English (en)

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-07-06

Filing date

2021-09-15

Publication date

2021-10-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40228991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUS2100038(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2021-09-15 Application filed by Novartis Ag filed Critical Novartis Ag

2021-10-28 Publication of HUS2100038I1 publication Critical patent/HUS2100038I1/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Virology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Pulmonology (AREA)
Hematology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Oncology (AREA)
Neurosurgery (AREA)
Mycology (AREA)
Microbiology (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)

HUS2100038C 2007-07-06 2021-09-15 Anti-CD20 antitest készítmények HUS2100038I1 (hu)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US94822007P	2007-07-06	2007-07-06
EP08781323.4A EP2170388B1 (en)	2007-07-06	2008-07-03	Anti-cd20 antibody formulations

Publications (1)

Publication Number	Publication Date
HUS2100038I1 true HUS2100038I1 (hu)	2021-10-28

Family

ID=40228991

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
HUE08781323A HUE031288T2 (hu)	2007-07-06	2008-07-03	Anti-CD20 antitest készítmények
HUE15155712A HUE038501T2 (hu)	2007-07-06	2008-07-03	Antitest készítmények
HUS2100038C HUS2100038I1 (hu)	2007-07-06	2021-09-15	Anti-CD20 antitest készítmények

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
HUE08781323A HUE031288T2 (hu)	2007-07-06	2008-07-03	Anti-CD20 antitest készítmények
HUE15155712A HUE038501T2 (hu)	2007-07-06	2008-07-03	Antitest készítmények

Country Status (38)

Country	Link
US (2)	US20110020328A1 (hu)
EP (2)	EP2889310B1 (hu)
JP (1)	JP5529017B2 (hu)
KR (2)	KR20100038092A (hu)
CN (1)	CN101820912B (hu)
AR (2)	AR067455A1 (hu)
AU (1)	AU2008275278B2 (hu)
BR (2)	BR122020026978B1 (hu)
CA (1)	CA2692681C (hu)
CL (1)	CL2008001984A1 (hu)
CO (1)	CO6270340A2 (hu)
CR (1)	CR11249A (hu)
CY (3)	CY1118419T1 (hu)
DK (2)	DK2170388T3 (hu)
DO (1)	DOP2010000001A (hu)
EA (1)	EA017994B1 (hu)
ES (2)	ES2610821T3 (hu)
FR (1)	FR21C1040I1 (hu)
HR (2)	HRP20170033T1 (hu)
HU (3)	HUE031288T2 (hu)
IL (1)	IL202950A (hu)
JO (1)	JO3219B1 (hu)
LT (3)	LT2170388T (hu)
MA (1)	MA31471B1 (hu)
MX (1)	MX2010000017A (hu)
MY (1)	MY210424A (hu)
NO (2)	NO2889310T3 (hu)
NZ (1)	NZ582250A (hu)
PE (1)	PE20090738A1 (hu)
PL (2)	PL2170388T3 (hu)
PT (2)	PT2889310T (hu)
SI (2)	SI2170388T1 (hu)
TR (1)	TR201802928T4 (hu)
TW (2)	TWI612060B (hu)
UA (1)	UA107557C2 (hu)
UY (1)	UY31210A1 (hu)
WO (1)	WO2009009407A1 (hu)
ZA (1)	ZA200909107B (hu)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20160279239A1 (en)	2011-05-02	2016-09-29	Immunomedics, Inc.	Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
US20160355591A1 (en)	2011-05-02	2016-12-08	Immunomedics, Inc.	Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
UA107557C2 (xx) *	2007-07-06	2015-01-26		Композиція антитіла офатумумабу
JP2010532790A (ja) *	2007-07-06	2010-10-14	グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー	抗体処方
AU2011219715B2 (en)	2010-02-26	2014-12-11	Novo Nordisk A/S	Stable antibody containing compositions
ES2765418T3 (es)	2010-03-01	2020-06-09	Bayer Healthcare Llc	Anticuerpos monoclonales optimizados contra el inhibidor de la ruta del factor tisular (TFPI)
JP6294075B2 (ja)	2010-05-28	2018-03-14	ノヴォノルディスクアー／エス	抗体及び防腐剤を含む安定した多用量組成物
US20140044727A1 (en) *	2011-04-07	2014-02-13	Glaxosmithkline Llc	Formulations with reduced viscosity
AU2012250924B2 (en)	2011-05-02	2017-05-25	Immunomedics, Inc.	Ultrafiltration concentration of allotype selected antibodies for small-volume administration
UA116189C2 (uk)	2011-05-02	2018-02-26	Мілленніум Фармасьютікалз, Інк.	КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
KR102014512B1 (ko) *	2011-05-02	2019-08-26	밀레니엄 파머슈티컬스 인코퍼레이티드	항-α4β7 항체에 대한 제형
UY34105A (es) *	2011-06-03	2012-07-31	Lg Life Sciences Ltd	Formulación líquida estable de etanercept
US9592297B2 (en)	2012-08-31	2017-03-14	Bayer Healthcare Llc	Antibody and protein formulations
UA117466C2 (uk)	2012-12-13	2018-08-10	Мерк Шарп Енд Доме Корп.	СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
US10117823B2 (en)	2013-03-12	2018-11-06	Primal Therapies, Inc.	Dental composition comprising chelator and base
EP2805730A1 (en) *	2013-05-21	2014-11-26	Bergen Teknologioverforing AS	Nitric oxide donor for the treatment of chronic fatigue syndrome
WO2015162504A1 (en)	2014-04-23	2015-10-29	Novartis Ag	Novel dosing and uses of ofatumumab
WO2016189491A1 (en) *	2015-05-28	2016-12-01	Glaxosmithkline Intellectual Property Development Limited	Novel formulation
CA3013336A1 (en) *	2016-02-03	2017-08-10	Oncobiologics, Inc.	Buffer formulations for enhanced antibody stability
PL3733712T3 (pl)	2016-08-15	2023-10-16	Novartis Ag	Schematy i sposoby leczenia stwardnienia rozsianego z zastosowaniem ofatumumabu
JPWO2018179138A1 (ja) *	2017-03-29	2020-02-06	持田製薬株式会社	抗体含有液体製剤
EP3606964A4 (en)	2017-04-03	2020-12-09	Immunomedics, Inc.	SUBCUTANE ADMINISTRATION OF ANTIBODY DRUG CONJUGATES FOR CANCER THERAPY
JOP20190260A1 (ar)	2017-05-02	2019-10-31	Merck Sharp & Dohme	صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
RU2019138507A (ru)	2017-05-02	2021-06-02	Мерк Шарп И Доум Корп.	Составы антител против lag3 и совместные составы антител против lag3 и антител против pd-1
CA3033195A1 (en) *	2018-02-09	2019-08-09	Ecolab Usa Inc.	Flowability testing systems and methods
MX2021005394A (es)	2018-11-07	2021-07-06	Merck Sharp & Dohme Llc	Co-formulaciones de anticuerpos anti-gen de activacion de linfocitos 3 (anti-lag3) y anticuerpos anti-muerte programada-1 (anti-pd-1).
TWI874341B (zh)	2018-12-18	2025-03-01	美商健生生物科技公司	產生異二聚體抗體之方法
KR20220062027A (ko)	2019-09-11	2022-05-13	노파르티스 아게	오파투무맙-치료된 환자에서의 다발성 경화증 이외의 병태의 관리
DK3864053T3 (da)	2019-09-11	2023-09-11	Novartis Ag	Behandling af rms ved at skifte terapi
CN112675126A (zh) *	2019-10-18	2021-04-20	百奥泰生物制药股份有限公司	抗cd20抗体制剂及其应用
JP7794757B2 (ja)	2020-04-09	2026-01-06	ノバルティスアーゲー	血清ＩｇＧを維持しながらＭＳを治療するためのオファツムマブ
MX2022013797A (es)	2020-05-08	2022-11-30	Genmab As	Anticuerpos biespecificos contra cd3 y cd20.
JP7057954B2 (ja) *	2020-09-03	2022-04-21	国立大学法人大阪大学	改善された保存安定性を有するタンパク質含有液体製剤
CA3216479A1 (en)	2021-04-14	2022-10-20	Novartis Ag	Ofatumumab for treating multiple sclerosis in asian patients
KR20240046200A (ko)	2021-08-16	2024-04-08	노파르티스 아게	소아 ms 치료를 위한 오파투무맙
KR20230150203A (ko) *	2022-04-20	2023-10-30	주식회사 알토스바이오로직스	오크렐리주맙(Ocrelizumab)을 포함하는 약학적 조성물과 그의 용도
CN116712390B (zh) *	2023-08-04	2023-11-14	上海览屹医药科技有限公司	一种高浓度高稳定性的抗体制剂及其制备方法
WO2025037335A1 (en) *	2023-08-12	2025-02-20	Dr. Reddy's Laboratories Limited	Formulations of anti-cd20 antibody

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4816567A (en)	1983-04-08	1989-03-28	Genentech, Inc.	Recombinant immunoglobin preparations
US4816401A (en) *	1985-09-09	1989-03-28	University Of Rochester	Serum free cell culture medium
DE3920358A1 (de)	1989-06-22	1991-01-17	Behringwerke Ag	Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
WO1993011161A1 (en)	1991-11-25	1993-06-10	Enzon, Inc.	Multivalent antigen-binding proteins
ES2190087T3 (es) *	1997-06-13	2003-07-16	Genentech Inc	Formulacion estabilizada de un anticuerpo.
HUP0203133A3 (en) *	1999-10-04	2005-07-28	Chiron Corp Emeryville	Stabilized liquid polypeptide-containing pharmaceutical compositions
US7754208B2 (en)	2001-01-17	2010-07-13	Trubion Pharmaceuticals, Inc.	Binding domain-immunoglobulin fusion proteins
WO2003068821A2 (en)	2002-02-14	2003-08-21	Immunomedics, Inc.	Anti-cd20 antibodies and fusion proteins thereof and methods of use
US20030180287A1 (en) *	2002-02-27	2003-09-25	Immunex Corporation	Polypeptide formulation
US20060182740A1 (en) *	2002-06-21	2006-08-17	Biogen Idec, Inc.	Buffered formulations for concentrating antibodies and methods of use thereof
ES2524694T3 (es) *	2002-10-17	2014-12-11	Genmab A/S	Anticuerpos monoclonales humanos contra CD20
AU2003299641C1 (en) *	2002-12-16	2016-06-02	Cormorant Pharmaceuticals Ab	Human monoclonal antibodies against interleukin 8 (IL-8)
US8084582B2 (en) *	2003-03-03	2011-12-27	Xencor, Inc.	Optimized anti-CD20 monoclonal antibodies having Fc variants
AR044388A1 (es)	2003-05-20	2005-09-07	Applied Molecular Evolution	Moleculas de union a cd20
EP1740946B1 (en)	2004-04-20	2013-11-06	Genmab A/S	Human monoclonal antibodies against cd20
DOP2006000029A (es) *	2005-02-07	2006-08-15	Genentech Inc	Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
NZ561137A (en) *	2005-03-08	2011-09-30	Pharmacia & Upjohn Co Llc	Stable anti-CTLA-4 antibody compositions with chelating agents
EP1942939B2 (en) *	2005-09-30	2021-07-07	Medimmune Limited	Interleukin-13 antibody composition
JP2010532790A (ja) *	2007-07-06	2010-10-14	グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー	抗体処方
UA107557C2 (xx) *	2007-07-06	2015-01-26		Композиція антитіла офатумумабу

2008
- 2008-03-07 UA UAA201001165A patent/UA107557C2/ru unknown
- 2008-07-03 SI SI200831738A patent/SI2170388T1/sl unknown
- 2008-07-03 CN CN200880105866.1A patent/CN101820912B/zh active Active
- 2008-07-03 PT PT151557121T patent/PT2889310T/pt unknown
- 2008-07-03 JO JOP/2008/0312A patent/JO3219B1/ar active
- 2008-07-03 NZ NZ582250A patent/NZ582250A/en unknown
- 2008-07-03 PT PT87813234T patent/PT2170388T/pt unknown
- 2008-07-03 PL PL08781323T patent/PL2170388T3/pl unknown
- 2008-07-03 CA CA2692681A patent/CA2692681C/en active Active
- 2008-07-03 HU HUE08781323A patent/HUE031288T2/hu unknown
- 2008-07-03 ES ES08781323.4T patent/ES2610821T3/es active Active
- 2008-07-03 BR BR122020026978-2A patent/BR122020026978B1/pt active IP Right Grant
- 2008-07-03 KR KR1020107000148A patent/KR20100038092A/ko not_active Withdrawn
- 2008-07-03 DK DK08781323.4T patent/DK2170388T3/en active
- 2008-07-03 HU HUE15155712A patent/HUE038501T2/hu unknown
- 2008-07-03 ES ES15155712.1T patent/ES2663504T3/es active Active
- 2008-07-03 AU AU2008275278A patent/AU2008275278B2/en active Active
- 2008-07-03 EA EA201070105A patent/EA017994B1/ru not_active IP Right Cessation
- 2008-07-03 JP JP2010516158A patent/JP5529017B2/ja active Active
- 2008-07-03 SI SI200831928T patent/SI2889310T1/en unknown
- 2008-07-03 HR HRP20170033TT patent/HRP20170033T1/hr unknown
- 2008-07-03 MY MYPI2010000010A patent/MY210424A/en unknown
- 2008-07-03 BR BRPI0814003-0A patent/BRPI0814003B1/pt active IP Right Grant
- 2008-07-03 WO PCT/US2008/069125 patent/WO2009009407A1/en not_active Ceased
- 2008-07-03 KR KR1020157019741A patent/KR101670454B1/ko active Active
- 2008-07-03 EP EP15155712.1A patent/EP2889310B1/en active Active
- 2008-07-03 NO NO15155712A patent/NO2889310T3/no unknown
- 2008-07-03 PL PL15155712T patent/PL2889310T3/pl unknown
- 2008-07-03 US US12/667,890 patent/US20110020328A1/en not_active Abandoned
- 2008-07-03 LT LTEP08781323.4T patent/LT2170388T/lt unknown
- 2008-07-03 LT LTEP15155712.1T patent/LT2889310T/lt unknown
- 2008-07-03 EP EP08781323.4A patent/EP2170388B1/en active Active
- 2008-07-03 TR TR2018/02928T patent/TR201802928T4/tr unknown
- 2008-07-03 DK DK15155712.1T patent/DK2889310T3/en active
- 2008-07-03 MX MX2010000017A patent/MX2010000017A/es active IP Right Grant
- 2008-07-04 CL CL2008001984A patent/CL2008001984A1/es unknown
- 2008-07-04 PE PE2008001136A patent/PE20090738A1/es active IP Right Grant
- 2008-07-04 TW TW104128324A patent/TWI612060B/zh active
- 2008-07-04 TW TW097125246A patent/TWI515204B/zh active
- 2008-07-04 UY UY31210A patent/UY31210A1/es not_active Application Discontinuation
- 2008-07-04 AR ARP080102910A patent/AR067455A1/es unknown
2009
- 2009-12-21 ZA ZA2009/09107A patent/ZA200909107B/en unknown
- 2009-12-24 IL IL202950A patent/IL202950A/en active IP Right Grant
- 2009-12-30 CO CO09149371A patent/CO6270340A2/es active IP Right Grant
- 2009-12-30 MA MA32460A patent/MA31471B1/fr unknown
2010
- 2010-01-05 DO DO2010000001A patent/DOP2010000001A/es unknown
- 2010-02-02 CR CR11249A patent/CR11249A/es unknown
2015
- 2015-02-19 US US14/625,881 patent/US20150158951A1/en not_active Abandoned
2017
- 2017-01-12 CY CY20171100043T patent/CY1118419T1/el unknown
- 2017-08-29 AR ARP170102392A patent/AR109461A2/es not_active Application Discontinuation
2018
- 2018-03-14 HR HRP20180440TT patent/HRP20180440T1/hr unknown
- 2018-03-20 CY CY20181100325T patent/CY1120047T1/el unknown
2021
- 2021-09-13 NO NO2021036C patent/NO2021036I1/no unknown
- 2021-09-14 CY CY2021027C patent/CY2021027I2/el unknown
- 2021-09-14 FR FR21C1040C patent/FR21C1040I1/fr active Active
- 2021-09-15 LT LTPA2021520C patent/LTPA2021520I1/lt unknown
- 2021-09-15 HU HUS2100038C patent/HUS2100038I1/hu unknown

Also Published As

Publication number	Publication date
MX2010000017A (es)	2010-04-07
TWI612060B (zh)	2018-01-21
CA2692681A1 (en)	2009-01-15
NZ582250A (en)	2012-04-27
EA017994B1 (ru)	2013-04-30
TR201802928T4 (tr)	2018-03-21
KR20100038092A (ko)	2010-04-12
KR20150088335A (ko)	2015-07-31
BRPI0814003B1 (pt)	2021-06-15
JO3219B1 (ar)	2018-03-08
PE20090738A1 (es)	2009-07-18
JP5529017B2 (ja)	2014-06-25
DK2889310T3 (en)	2018-03-26
ES2610821T3 (es)	2017-05-03
PL2889310T3 (pl)	2018-06-29
JP2011526880A (ja)	2011-10-20
CL2008001984A1 (es)	2009-01-09
KR101670454B1 (ko)	2016-10-31
CY2021027I1 (el)	2021-12-31
ZA200909107B (en)	2012-12-27
IL202950A0 (en)	2011-08-01
UA107557C2 (xx)	2015-01-26
EP2170388B1 (en)	2016-10-12
US20150158951A1 (en)	2015-06-11
MY210424A (en)	2025-09-22
BR122020026978B1 (pt)	2021-09-28
TW201623334A (zh)	2016-07-01
FR21C1040I1 (fr)	2021-11-19
PL2170388T3 (pl)	2017-06-30
EP2170388A4 (en)	2011-07-06
AU2008275278A1 (en)	2009-01-15
WO2009009407A1 (en)	2009-01-15
TWI515204B (zh)	2016-01-01
PT2170388T (pt)	2017-01-04
IL202950A (en)	2014-05-28
AR067455A1 (es)	2009-10-14
PT2889310T (pt)	2018-03-26
MA31471B1 (fr)	2010-06-01
SI2170388T1 (sl)	2017-01-31
TW200914466A (en)	2009-04-01
EP2889310B1 (en)	2017-12-20
EA201070105A1 (ru)	2010-08-30
HK1207652A1 (en)	2016-02-19
NO2021036I1 (no)	2021-09-13
HK1141979A1 (zh)	2010-11-26
CO6270340A2 (es)	2011-04-20
HRP20180440T1 (hr)	2018-04-20
UY31210A1 (es)	2009-01-30
DOP2010000001A (es)	2010-01-31
CR11249A (es)	2010-03-08
BRPI0814003A2 (pt)	2015-02-03
CY1120047T1 (el)	2018-12-12
US20110020328A1 (en)	2011-01-27
AR109461A2 (es)	2018-12-12
SI2889310T1 (en)	2018-04-30
ES2663504T3 (es)	2018-04-13
EP2170388A1 (en)	2010-04-07
HRP20170033T1 (hr)	2017-03-24
NO2889310T3 (hu)	2018-05-19
LTPA2021520I1 (hu)	2021-10-11
CN101820912B (zh)	2014-03-12
CN101820912A (zh)	2010-09-01
LT2170388T (lt)	2017-01-10
EP2889310A1 (en)	2015-07-01
CY1118419T1 (el)	2017-06-28
CA2692681C (en)	2018-12-04
DK2170388T3 (en)	2017-01-16
AU2008275278B2 (en)	2011-04-14
CY2021027I2 (el)	2021-12-31
LT2889310T (lt)	2018-03-26
HUE031288T2 (hu)	2017-06-28
HUE038501T2 (hu)	2018-10-29

Publication	Publication Date	Title
HUS2100038I1 (hu)	2021-10-28	Anti-CD20 antitest készítmények
CY2019004I1 (el)	2019-11-27	Τροποποιημενα αντισωματα αντι-ιl-23ρ19
DK3118220T3 (da)	2019-09-23	Protein
DK2234600T3 (da)	2014-09-08	Antistofformulering
PL3059246T3 (pl)	2018-11-30	Zmodyfikowany region stały przeciwciała
DK2068886T3 (da)	2013-11-18	Lipidholdige præparater
BRPI0814252A2 (pt)	2015-04-14	Formulações de anticorpo
BRPI0809677A2 (pt)	2014-10-07	Anticorpos anti-ige
BRPI0807991A2 (pt)	2014-06-17	Anticorpos anti-il-23r elaborados.
BRPI0907237A2 (pt)	2015-07-14	Anticorpo anti-cldn6
HRP20171011T1 (hr)	2017-09-22	ANTI-eMET ANTITIJELO
BRPI0914155A2 (pt)	2015-10-20	preparações de xampu
EP2215246A4 (en)	2011-08-10	PROTEIN SCAFFOLDS
EP2211903A4 (en)	2011-07-06	CLL-1 ANTIBODY
DK2046826T3 (da)	2011-10-24	Exendin-fusionsproteiner
EP2181121A4 (en)	2012-07-11	CHIMÄRE ANTIGENE
SI2126093T1 (sl)	2013-01-31	IzboljĹˇanje priprave proteinov
IL212175B (en)	2019-08-29	Muc1* antibodies
BRPI0814971A2 (pt)	2015-02-03	Proteína
EP2337798A4 (en)	2012-10-24	SPECIFIC ANTIBODIES OF THE ASB
EP2172483A4 (en)	2010-08-04	ANTI-MUC17 ANTIBODY
BRPI0817427A2 (pt)	2015-06-16	Anticorpo anti-bst2
BRPI0914152A2 (pt)	2015-10-20	preparações de xampu
BRPI0909633A2 (pt)	2015-09-22	anticorpos anti-tyrp1
EP2212431A4 (en)	2011-05-11	ANTIBODY AGAINST IREM-1