HUS1900049I1 - Prokarióta fenilalanin ammónia-liáz készítmények és azok alkalmazási eljárásai - Google Patents

Prokarióta fenilalanin ammónia-liáz készítmények és azok alkalmazási eljárásai

Info

Publication number: HUS1900049I1
Authority: HU; Hungary
Prior art keywords: compositions; lyase; methods; phenylalanine ammonia; prokaryotic phenylalanine
Prior art date: 2007-05-25

Application number

HUS1900049C

Other languages

English (en)

Original Assignee

Biomarin Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-25

Filing date

2019-10-18

Publication date

2019-11-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39868905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUS1900049(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2019-10-18 Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc

2019-11-28 Publication of HUS1900049I1 publication Critical patent/HUS1900049I1/hu

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/51—Lyases (4)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Oncology (AREA)
Obesity (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

HUS1900049C 2007-05-25 2019-10-18 Prokarióta fenilalanin ammónia-liáz készítmények és azok alkalmazási eljárásai HUS1900049I1 (hu)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11/807,227 US7534595B2 (en)	2006-06-12	2007-05-25	Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
EP08754717.0A EP2152868B1 (en)	2007-05-25	2008-05-23	Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using said compositions

Publications (1)

Publication Number	Publication Date
HUS1900049I1 true HUS1900049I1 (hu)	2019-11-28

Family

ID=39868905

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HUE08754717A HUE025784T2 (hu)	2007-05-25	2008-05-23	Prokarióta fenilalanin ammónia-liáz készítmények és azok alkalmazási eljárásai
HUS1900049C HUS1900049I1 (hu)	2007-05-25	2019-10-18	Prokarióta fenilalanin ammónia-liáz készítmények és azok alkalmazási eljárásai

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
HUE08754717A HUE025784T2 (hu)	2007-05-25	2008-05-23	Prokarióta fenilalanin ammónia-liáz készítmények és azok alkalmazási eljárásai

Country Status (29)

Country	Link
US (1)	US7534595B2 (hu)
EP (2)	EP2657335A1 (hu)
JP (1)	JP5670183B2 (hu)
KR (2)	KR20150038753A (hu)
CN (1)	CN101842482B (hu)
AR (2)	AR066716A1 (hu)
AU (1)	AU2008263190B2 (hu)
BR (1)	BRPI0811267B8 (hu)
CA (1)	CA2687450C (hu)
CL (1)	CL2008001497A1 (hu)
CY (2)	CY1116894T1 (hu)
DK (1)	DK2152868T3 (hu)
EA (1)	EA018443B1 (hu)
ES (1)	ES2551315T3 (hu)
HR (1)	HRP20151268T1 (hu)
HU (2)	HUE025784T2 (hu)
IL (1)	IL202132A (hu)
LT (1)	LTC2152868I2 (hu)
LU (1)	LUC00133I2 (hu)
MX (1)	MX2009012453A (hu)
MY (1)	MY151413A (hu)
NL (1)	NL301011I2 (hu)
NO (1)	NO2019037I1 (hu)
PE (1)	PE20090315A1 (hu)
PL (1)	PL2152868T3 (hu)
PT (1)	PT2152868E (hu)
SI (1)	SI2152868T1 (hu)
TW (1)	TWI418633B (hu)
WO (1)	WO2008153776A1 (hu)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7531341B1 (en)	2006-06-12	2009-05-12	Biomarin Pharmaceutical Inc.	Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7534595B2 (en) *	2006-06-12	2009-05-19	Biomarin Pharmaceutical Inc.	Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7560263B2 (en) *	2007-08-17	2009-07-14	Biomarin Pharmaceutical Inc.	Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
WO2010014225A2 (en) *	2008-07-30	2010-02-04	Biomarin Pharmaceutical Inc.	Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase
JP5828844B2 (ja) *	2010-02-04	2015-12-09	ビオマリンプハルマセウトイカルインコーポレイテッド	原核生物フェニルアラニンアンモニアリアーゼ変異体の組成物、及び、その組成物を用いる方法
WO2014018832A1 (en) *	2012-07-27	2014-01-30	University Of North Texas	Genetically modified probiotic for the treatment of phenylketonuria (pku) disease
KR102218930B1 (ko)	2013-04-18	2021-02-23	코덱시스, 인코포레이티드	조작된 페닐알라닌 암모니아 리아제 폴리펩티드
EP3071515A2 (en)	2013-11-18	2016-09-28	Rubius Therapeutics, Inc.	Synthetic membrane-receiver complexes
HUE054471T2 (hu)	2014-04-01	2021-09-28	Rubius Therapeutics Inc	Immunmodulációs módszerek és készítmények
HUE056444T2 (hu)	2014-04-16	2022-02-28	Codexis Inc	Génmódosított tirozin-ammónia-liáz
KR102702200B1 (ko)	2014-12-22	2024-09-02	코덱시스, 인코포레이티드	인간 알파-갈락토시다제 변이체
TWI797060B (zh)	2015-08-04	2023-04-01	美商再生元醫藥公司	補充牛磺酸之細胞培養基及用法
KR102604510B1 (ko)	2016-07-26	2023-11-23	바이오마린 파머수티컬 인크.	신규 아데노-관련 바이러스 캡시드 단백질
MY190749A (en) *	2016-08-30	2022-05-12	Mitsubishi Chem Corp	Method for producing mutant enzyme, and mutant alcohol acyltransferase
CN106497905A (zh) *	2016-12-14	2017-03-15	江南大学	一株鱼腥藻来源的苯丙氨酸脱氨酶的突变体
EP3579867A4 (en) *	2017-02-13	2021-03-10	Codexis, Inc.	MANIPULATED PHENYLALANINE AMMONIA LYASE POLYPEPTIDES
CN107653275A (zh) *	2017-10-30	2018-02-02	安徽工程大学	D‑苯丙氨酸的制备方法
CN108004225B (zh) *	2017-12-19	2020-05-08	江南大学	一种成团泛菌来源的苯丙氨酸氨基变位酶的突变体
US11739345B2 (en)	2018-05-09	2023-08-29	Biomarin Pharmaceutical Inc.	Methods of treating phenylketonuria
TW202005978A (zh)	2018-05-14	2020-02-01	美商拜奧馬林製藥公司	新穎肝靶向腺相關病毒載體
US10900055B2 (en) *	2018-06-12	2021-01-26	Codexis, Inc.	Engineered tyrosine ammonia lyase
US11198861B2 (en) *	2018-07-12	2021-12-14	Codexis, Inc.	Engineered phenylalanine ammonia lyase polypeptides
WO2020123286A1 (en)	2018-12-14	2020-06-18	Codexis, Inc.	Engineered tyrosine ammonia lyase
CA3123598A1 (en)	2018-12-20	2020-06-25	Codexis, Inc.	Human alpha-galactosidase variants
CN110456056A (zh) *	2019-07-22	2019-11-15	浙江大学	一种新生儿苯丙酮尿症无创筛查试纸的制备方法
JP7699107B2 (ja)	2019-08-30	2025-06-26	ソシエテ・デ・プロデュイ・ネスレ・エス・アー	操作されたリパーゼ改変体
BR112022011760A2 (pt)	2019-12-20	2022-08-30	Codexis Inc	Fragmento de alfa glicosidase ácida recombinante e/ou de alfa glicosidase ácida recombinante biologicamente ativa, alfa glicosidase ácida recombinante, composição, sequência polinucleotídica recombinante, vetor de expressão, vetor de expressão pdh, célula hospedeira, método para produzir uma variante de alfa glicosidase ácida recombinante, variante de alfa glicosidase ácida recombinante, composição farmacêutica para o tratamento da doença de pompe, composição farmacêutica, método para tratar e/ou prevenir os sintomas da doença de pompe em um indivíduo, e, uso das composições
CA3168922A1 (en)	2020-02-04	2021-08-12	Codexis, Inc.	Engineered leucine decarboxylases
US20230183712A1 (en) *	2020-02-19	2023-06-15	Trustees Of Tufts College	Methods for engineering amino acid ammonia lyase enzymes and enzymes thereby obtained
TW202144575A (zh)	2020-04-03	2021-12-01	美商拜奧馬林製藥公司	使用ａａｖ及治療調配物之苯酮尿症治療
CN116897205A (zh)	2020-08-28	2023-10-17	科德克希思公司	工程化淀粉酶变体
WO2022047262A1 (en)	2020-08-28	2022-03-03	Codexis, Inc.	Engineered protease variants
EP4341394A4 (en) *	2021-05-19	2025-04-09	BioMarin Pharmaceutical Inc.	Compositions of prokaryotic phenylalanine ammonia lyase and methods for treating adolescent patients
CA3220735A1 (en)	2021-05-21	2022-11-24	Codexis, Inc.	Engineered methionine gamma lyase variants
US20250000957A1 (en) *	2021-09-16	2025-01-02	Arcturus Therapeutics, Inc.	Compositions and methods for treating phenylketonuria
CA3236731A1 (en)	2021-11-01	2023-05-04	Jonathan Benjamin ASFAHA	Engineered leucine decarboxylases
CN117417925A (zh) *	2022-07-18	2024-01-19	浙江泽科塔生物医药有限公司	Pal变体、包含该pal变体的药物组合物以及用于制备该pal变体的方法
CN118931888A (zh) *	2023-05-09	2024-11-12	重庆派金生物科技有限公司	苯丙氨酸裂解酶突变体及其偶联物或其药学上可接受的盐
GB202307239D0 (en)	2023-05-15	2023-06-28	Evox Therapeutics Ltd	Gene therapies for Phenylketonuria
CN116478975B (zh) *	2023-06-16	2023-09-01	苏州优信合生技术有限公司	高活性苯丙氨酸解氨酶突变体及其表达菌株
WO2025106759A1 (en)	2023-11-17	2025-05-22	Biomarin Pharmaceutical Inc.	Conjugates of phenylalanine ammonia-lyase and poegma and methods for their use

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4252822A (en)	1979-12-26	1981-02-24	Children's Hospital Medical Center	Method for treating phenylketonuria
US4562151A (en)	1983-09-06	1985-12-31	Monsanto Company	Stabilization of L-phenylalanine ammonia-lyase enzyme
US5206344A (en)	1985-06-26	1993-04-27	Cetus Oncology Corporation	Interleukin-2 muteins and polymer conjugation thereof
US5166322A (en)	1989-04-21	1992-11-24	Genetics Institute	Cysteine added variants of interleukin-3 and chemical modifications thereof
US5766897A (en)	1990-06-21	1998-06-16	Incyte Pharmaceuticals, Inc.	Cysteine-pegylated proteins
PT668933E (pt)	1992-11-19	2003-02-28	Anticancer Inc	Utilizacao de metioninase como agente anti-tumor em qimioterapia anti-metionina
ES2287926T3 (es)	1992-12-04	2007-12-16	Me Medical Enzymes Ag	Glutaminasa manipulada geneticamente y su uso en terapia.
US5849535A (en)	1995-09-21	1998-12-15	Genentech, Inc.	Human growth hormone variants
DK75593D0 (hu)	1993-06-25	1993-06-25	Novo Nordisk As
JPH09510352A (ja) *	1994-03-15	1997-10-21	プリズムファーマシューティカルズ，インコーポレイティド	遺伝子療法及び前部の眼疾患のためのヘパリン結合成長因子
CU22585A1 (es) *	1995-11-17	1999-11-03	Centro Inmunologia Molecular	Anticuerpos monoclonales antiidiótipos (ab2) de tipo igg con alta conectividad idiotípica y composiciones farmacéuticas que los contienen. su uso como inmunoreguladores de la respuesta inmune.
US6548644B1 (en)	1997-03-10	2003-04-15	Immunex Corporation	Site protected protein modification
US6183738B1 (en)	1997-05-12	2001-02-06	Phoenix Pharamacologics, Inc.	Modified arginine deiminase
US5981239A (en)	1997-09-24	1999-11-09	Great Lakes Chemical Corp.	Synthesis of optically active phenylalanine analogs using Rhodotorula graminis
EP1042459A4 (en) *	1997-12-24	2003-07-23	Diatech Pty Ltd	BIFUNCTIONAL MOLECULES
TWI227241B (en) *	1998-06-20	2005-02-01	United Biomedical Inc	IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate
US6451986B1 (en)	1998-06-22	2002-09-17	Immunex Corporation	Site specific protein modification
US6461849B1 (en)	1998-10-13	2002-10-08	Novozymes, A/S	Modified polypeptide
US6403312B1 (en)	1998-10-16	2002-06-11	Xencor	Protein design automatic for protein libraries
US6686164B1 (en)	1998-10-30	2004-02-03	Novozymes A/S	Low allergenic protein variants
IL138990A0 (en)	1999-02-12	2001-11-25	Biostream Inc	Matrices for drug delivery and methods for making and using the same
AU783208B2 (en) *	1999-12-09	2005-10-06	Novartis Vaccines And Diagnostics, Inc.	Method for administering a cytokine to the central nervous system and the lymphatic system
US6586398B1 (en)	2000-04-07	2003-07-01	Amgen, Inc.	Chemically modified novel erythropoietin stimulating protein compositions and methods
US6939541B2 (en)	2000-04-14	2005-09-06	University Of South Carolina	Cloning, overexpression and therapeutic use of bioactive histidine ammonia lyase
US6967097B2 (en)	2000-07-24	2005-11-22	Pcbu Services, Inc.	Phenylalainine ammonia lyase polypeptide and polynucleotide sequences and methods of obtaining and using same
CN1461344A (zh) *	2000-07-25	2003-12-10	免疫医疗公司	多价靶结合蛋白
AU2001294774A1 (en) *	2000-09-26	2002-04-08	The Regents Of The University Of California	Characterization of phenylalanine ammonia-lyase (pal) gene in wounded lettuce
AU2002213843B2 (en) *	2000-11-10	2008-02-07	F. Hoffmann-La Roche Ltd.	Apolipoprotein analogues
KR20040088538A (ko)	2002-02-26	2004-10-16	이 아이 듀폰 디 네모아 앤드 캄파니	유전 인자의 재조합 방법
EP2351770A1 (en) *	2002-07-17	2011-08-03	Cytos Biotechnology AG	Molecular antigen arrays using a virus like particle derived from the ap205 coat protein
CA2506026A1 (en)	2002-11-14	2004-05-27	The Scripps Research Institute	Crystalline form of fatty acid amine hydrolase (faah)
RU2403262C2 (ru) *	2003-06-11	2010-11-10	Уайт	Выделенный полипептид ib альфа гликопротеина тромбоцитов человека, слитый белок, молекула днк (варианты), экспрессирующий вектор (варианты), клетка (варианты), способ экспрессии полипептида, способ экспрессии слитого белка, фармацевтическая композиция (варианты), способ ингибирования прикрепления клетки крови к биологической ткани в биологической системе, способ ингибирования прикрепления белка к биологической ткани в биологической системе и способ лечения нарушения
FR2868318B1 (fr) *	2004-04-01	2012-11-16	Commissariat Energie Atomique	Antigene tat stabilise et ses applications pour la vaccination anti-vih
US7670595B2 (en) *	2004-06-28	2010-03-02	Merck Patent Gmbh	Fc-interferon-beta fusion proteins
JP2008513027A (ja)	2004-09-17	2008-05-01	バイオマリンファーマシューティカルインコーポレイテッド	フェニルアラニンアンモニアーリアーゼの改変体および化学的に修飾された改変体
US20090038023A1 (en)	2005-03-10	2009-02-05	Verenium Corporation	Lyase Enzymes, Nucleic Acids Encoding Them and Methods For Making and Using Them
US7534595B2 (en) *	2006-06-12	2009-05-19	Biomarin Pharmaceutical Inc.	Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
WO2008069958A2 (en)	2006-12-01	2008-06-12	The Salk Institute For Biological Studies	Substrate switched ammonia lyases and mutases
US7560263B2 (en)	2007-08-17	2009-07-14	Biomarin Pharmaceutical Inc.	Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof

2007
- 2007-05-25 US US11/807,227 patent/US7534595B2/en active Active
2008
- 2008-05-23 JP JP2010509405A patent/JP5670183B2/ja active Active
- 2008-05-23 EP EP13169362.4A patent/EP2657335A1/en not_active Withdrawn
- 2008-05-23 MY MYPI20094868 patent/MY151413A/en unknown
- 2008-05-23 CA CA2687450A patent/CA2687450C/en active Active
- 2008-05-23 HU HUE08754717A patent/HUE025784T2/hu unknown
- 2008-05-23 PE PE2008000889A patent/PE20090315A1/es active IP Right Grant
- 2008-05-23 SI SI200831540T patent/SI2152868T1/sl unknown
- 2008-05-23 PL PL08754717T patent/PL2152868T3/pl unknown
- 2008-05-23 BR BRPI0811267A patent/BRPI0811267B8/pt active IP Right Grant
- 2008-05-23 AR ARP080102198A patent/AR066716A1/es active IP Right Grant
- 2008-05-23 CN CN200880016898.4A patent/CN101842482B/zh active Active
- 2008-05-23 EP EP08754717.0A patent/EP2152868B1/en active Active
- 2008-05-23 MX MX2009012453A patent/MX2009012453A/es active IP Right Grant
- 2008-05-23 DK DK08754717.0T patent/DK2152868T3/en active
- 2008-05-23 WO PCT/US2008/006661 patent/WO2008153776A1/en not_active Ceased
- 2008-05-23 EA EA200970980A patent/EA018443B1/ru unknown
- 2008-05-23 KR KR20157007821A patent/KR20150038753A/ko not_active Ceased
- 2008-05-23 ES ES08754717.0T patent/ES2551315T3/es active Active
- 2008-05-23 AU AU2008263190A patent/AU2008263190B2/en active Active
- 2008-05-23 KR KR1020097027018A patent/KR101603796B1/ko active Active
- 2008-05-23 PT PT87547170T patent/PT2152868E/pt unknown
- 2008-05-23 CL CL2008001497A patent/CL2008001497A1/es unknown
- 2008-05-23 HR HRP20151268TT patent/HRP20151268T1/hr unknown
- 2008-05-23 TW TW097119178A patent/TWI418633B/zh active
2009
- 2009-11-15 IL IL202132A patent/IL202132A/en active IP Right Grant
2015
- 2015-11-06 CY CY20151100997T patent/CY1116894T1/el unknown
2018
- 2018-01-17 AR ARP180100106A patent/AR110834A2/es unknown
2019
- 2019-10-09 NL NL301011C patent/NL301011I2/nl unknown
- 2019-10-10 LT LTPA2019517C patent/LTC2152868I2/lt unknown
- 2019-10-14 LU LU00133C patent/LUC00133I2/fr unknown
- 2019-10-16 NO NO2019037C patent/NO2019037I1/no unknown
- 2019-10-17 CY CY2019039C patent/CY2019039I2/el unknown
- 2019-10-18 HU HUS1900049C patent/HUS1900049I1/hu unknown

Also Published As

Publication number	Publication date
CY2019039I1 (el)	2020-05-29
WO2008153776A1 (en)	2008-12-18
NL301011I2 (nl)	2020-05-13
EA200970980A1 (ru)	2010-04-30
NL301011I1 (nl)	2019-10-16
BRPI0811267B8 (pt)	2021-05-25
DK2152868T3 (en)	2015-11-16
LUC00133I1 (hu)	2019-10-16
AU2008263190B2 (en)	2014-04-17
PT2152868E (pt)	2015-11-13
TW200902052A (en)	2009-01-16
EP2657335A1 (en)	2013-10-30
KR20150038753A (ko)	2015-04-08
CA2687450A1 (en)	2008-12-18
MX2009012453A (es)	2010-01-25
HK1135141A1 (zh)	2010-05-28
AU2008263190A1 (en)	2008-12-18
BRPI0811267A2 (pt)	2014-10-07
SI2152868T1 (sl)	2015-12-31
PL2152868T3 (pl)	2016-01-29
KR20100024437A (ko)	2010-03-05
JP2010529835A (ja)	2010-09-02
WO2008153776A8 (en)	2009-07-30
IL202132A0 (en)	2010-06-16
ES2551315T3 (es)	2015-11-18
LTC2152868I2 (lt)	2020-09-25
HUE025784T2 (hu)	2016-05-30
AR110834A2 (es)	2019-05-08
KR101603796B1 (ko)	2016-03-17
US20080008695A1 (en)	2008-01-10
HRP20151268T1 (hr)	2015-12-18
CA2687450C (en)	2019-03-26
EA018443B1 (ru)	2013-08-30
PE20090315A1 (es)	2009-03-19
CN101842482B (zh)	2014-10-22
JP5670183B2 (ja)	2015-02-18
CL2008001497A1 (es)	2009-01-09
BRPI0811267B1 (pt)	2020-11-10
CY1116894T1 (el)	2017-04-05
MY151413A (en)	2014-05-30
EP2152868B1 (en)	2015-09-02
TWI418633B (zh)	2013-12-11
CN101842482A (zh)	2010-09-22
AR066716A1 (es)	2009-09-09
US7534595B2 (en)	2009-05-19
LTPA2019517I1 (lt)	2019-10-25
NO2019037I1 (no)	2019-10-16
IL202132A (en)	2017-06-29
LUC00133I2 (hu)	2020-07-16
CY2019039I2 (el)	2020-05-29
EP2152868A1 (en)	2010-02-17

Publication	Publication Date	Title
HUS1900049I1 (hu)	2019-11-28	Prokarióta fenilalanin ammónia-liáz készítmények és azok alkalmazási eljárásai
IL257437B (en)	2019-06-30	Compositions of prokaryotic phenylalanine ammonia lyase variants and methods of using the compositions
PT2175875T (pt)	2016-11-21	Composições de fenilalanina amoníaco/liase procariótica e métodos de tratamento de cancro utilizando as suas composições
ZA201001300B (en)	2010-11-24	Antigen-asjuvant compositions and methods
PT2101766T (pt)	2016-12-28	Composições e métodos de utilização de (r)-pramipexole
AP2646A (en)	2013-04-17	Peptide sequences and compositions
IL195619A0 (en)	2009-09-01	Compositions and methods for joininig non-conjoined iumens
HRP20160902T1 (hr)	2016-09-23	Pripravci i postupci uporabe forbolskih estera
GB0717864D0 (en)	2007-10-24	Peptide sequences and compositions
EP2101731A4 (en)	2011-04-20	PROCESSES AND COMPOSITIONS WITH END OXIFES
IL238404A0 (en)	2015-06-30	Preparations and methods to prevent influenza
PL2101766T3 (pl)	2017-04-28	Kompozycje i sposoby stosowania (R)-pramipeksolu
GB0721291D0 (en)	2007-12-12	Methods and compositions
GB0719526D0 (en)	2007-11-14	Compositions and methods
GB0605247D0 (en)	2006-04-26	Compositions and methods for immunisation
GB0617171D0 (en)	2006-10-11	Novel compositions and methods
ZA201004894B (en)	2011-05-25	Nuctraceutical composition and methods of use
ZA201004893B (en)	2011-05-25	Nuctraceutical composition and methods of use
GB0723775D0 (en)	2008-01-16	Methods and compositions
GB0724549D0 (en)	2008-01-30	Compositions and methods
GB0717683D0 (en)	2007-10-17	Compositions and methods
GB0616269D0 (en)	2006-09-27	Methods and compositions
GB0607565D0 (en)	2006-05-24	Methods and compositions
GB0625230D0 (en)	2007-01-24	Compositions and methods
HK1143743A (en)	2011-01-14	Peptide sequences and compositions