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NL301011I1 - pegvaliase - Google Patents

pegvaliase

Info

Publication number
NL301011I1
NL301011I1 NL301011C NL301011C NL301011I1 NL 301011 I1 NL301011 I1 NL 301011I1 NL 301011 C NL301011 C NL 301011C NL 301011 C NL301011 C NL 301011C NL 301011 I1 NL301011 I1 NL 301011I1
Authority
NL
Netherlands
Prior art keywords
pegvaliase
Prior art date
Application number
NL301011C
Other languages
English (en)
Other versions
NL301011I2 (nl
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39868905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL301011(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of NL301011I1 publication Critical patent/NL301011I1/nl
Publication of NL301011I2 publication Critical patent/NL301011I2/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL301011C 2007-05-25 2019-10-09 pegvaliase NL301011I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/807,227 US7534595B2 (en) 2006-06-12 2007-05-25 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
PCT/US2008/006661 WO2008153776A1 (en) 2007-05-25 2008-05-23 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using said compositions

Publications (2)

Publication Number Publication Date
NL301011I1 true NL301011I1 (nl) 2019-10-16
NL301011I2 NL301011I2 (nl) 2020-05-13

Family

ID=39868905

Family Applications (1)

Application Number Title Priority Date Filing Date
NL301011C NL301011I2 (nl) 2007-05-25 2019-10-09 pegvaliase

Country Status (29)

Country Link
US (1) US7534595B2 (nl)
EP (2) EP2152868B1 (nl)
JP (1) JP5670183B2 (nl)
KR (2) KR20150038753A (nl)
CN (1) CN101842482B (nl)
AR (2) AR066716A1 (nl)
AU (1) AU2008263190B2 (nl)
BR (1) BRPI0811267B8 (nl)
CA (1) CA2687450C (nl)
CL (1) CL2008001497A1 (nl)
CY (2) CY1116894T1 (nl)
DK (1) DK2152868T3 (nl)
EA (1) EA018443B1 (nl)
ES (1) ES2551315T3 (nl)
HR (1) HRP20151268T1 (nl)
HU (2) HUE025784T2 (nl)
IL (1) IL202132A (nl)
LT (1) LTC2152868I2 (nl)
LU (1) LUC00133I2 (nl)
MX (1) MX2009012453A (nl)
MY (1) MY151413A (nl)
NL (1) NL301011I2 (nl)
NO (1) NO2019037I1 (nl)
PE (1) PE20090315A1 (nl)
PL (1) PL2152868T3 (nl)
PT (1) PT2152868E (nl)
SI (1) SI2152868T1 (nl)
TW (1) TWI418633B (nl)
WO (1) WO2008153776A1 (nl)

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US7534595B2 (en) * 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7531341B1 (en) 2006-06-12 2009-05-12 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7537923B2 (en) * 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
WO2010014225A2 (en) * 2008-07-30 2010-02-04 Biomarin Pharmaceutical Inc. Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase
WO2011097335A2 (en) * 2010-02-04 2011-08-11 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase variants and methods of using compositions thereof
EP3222288A1 (en) * 2012-07-27 2017-09-27 University of North Texas Genetically modified probiotic for the treatment of phenylketonuria (pku) disease
HRP20190928T1 (hr) 2013-04-18 2019-07-26 Codexis, Inc. Modificirani fenilalanin amonijak-liazni polipeptidi
CA2930665A1 (en) 2013-11-18 2015-05-21 Rubius Therapeutics, Inc. Synthetic membrane-receiver complexes
PL3125927T3 (pl) 2014-04-01 2021-07-19 Rubius Therapeutics, Inc. Sposoby i kompozycje do immunomodulacji
EP3928787A1 (en) * 2014-04-16 2021-12-29 Codexis, Inc. Engineered tyrosine ammonia lyase
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CN106497905A (zh) * 2016-12-14 2017-03-15 江南大学 一株鱼腥藻来源的苯丙氨酸脱氨酶的突变体
BR112019016634A2 (pt) * 2017-02-13 2020-04-07 Codexis Inc polipeptídeos, sequência de polinucleotídeos modificados por engenharia, vetor de expressão, célula hospedeira, métodos para produzir um polipeptídeo de fenilalanina amônia liase modificado por engenharia em uma célula hospedeira e para tratar e/ou prevenir os sintomas de fenilcetonúria em um indivíduo, composição, e, uso
CN107653275A (zh) * 2017-10-30 2018-02-02 安徽工程大学 D‑苯丙氨酸的制备方法
CN108004225B (zh) * 2017-12-19 2020-05-08 江南大学 一种成团泛菌来源的苯丙氨酸氨基变位酶的突变体
AU2019265560A1 (en) 2018-05-09 2020-11-26 Biomarin Pharmaceutical Inc. Methods of treating phenylketonuria
TW202005978A (zh) 2018-05-14 2020-02-01 美商拜奧馬林製藥公司 新穎肝靶向腺相關病毒載體
CA3102968A1 (en) 2018-06-12 2019-12-19 Codexis, Inc. Engineered tyrosine ammonia lyase
US11198861B2 (en) * 2018-07-12 2021-12-14 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
AU2019397401A1 (en) 2018-12-14 2021-06-17 Codexis, Inc. Engineered tyrosine ammonia lyase
KR102898199B1 (ko) 2018-12-20 2025-12-09 코덱시스, 인코포레이티드 인간 알파 갈락토시다제 변이체
CN110456056A (zh) * 2019-07-22 2019-11-15 浙江大学 一种新生儿苯丙酮尿症无创筛查试纸的制备方法
CA3152763A1 (en) 2019-08-30 2021-03-04 Codexis, Inc. Engineered lipase variants
JP2023507575A (ja) 2019-12-20 2023-02-24 コデクシス， インコーポレイテッド 操作された酸性アルファ－グルコシダーゼバリアント
IL295169A (en) 2020-02-04 2022-09-01 Codexis Inc Engineered leucine decarboxylases
US20230183712A1 (en) * 2020-02-19 2023-06-15 Trustees Of Tufts College Methods for engineering amino acid ammonia lyase enzymes and enzymes thereby obtained
AR122409A1 (es) 2020-04-03 2022-09-07 Biomarin Pharm Inc Tratamiento de la fenilcetonuria con aav y formulaciones terapéuticas
CN117098847A (zh) 2020-08-28 2023-11-21 科德克希思公司 工程化蛋白酶变体
MX2023002421A (es) 2020-08-28 2023-05-18 Codexis Inc Variantes de amilasa modificadas geneticamente.
US11918633B2 (en) * 2021-05-19 2024-03-05 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating adolescent subjects
TW202313969A (zh) 2021-05-21 2023-04-01 美商克迪科思股份有限公司 經工程化的甲硫胺酸γ解離酶變異體
WO2023044381A1 (en) * 2021-09-16 2023-03-23 Arcturus Therapeutics, Inc. Compositions and methods for treating phenylketonuria
US12502421B2 (en) 2021-11-01 2025-12-23 Syntis Bio, Inc. Engineered leucine decarboxylases
CN117417925A (zh) * 2022-07-18 2024-01-19 浙江泽科塔生物医药有限公司 Pal变体、包含该pal变体的药物组合物以及用于制备该pal变体的方法
CN118931888A (zh) * 2023-05-09 2024-11-12 重庆派金生物科技有限公司 苯丙氨酸裂解酶突变体及其偶联物或其药学上可接受的盐
GB202307239D0 (en) 2023-05-15 2023-06-28 Evox Therapeutics Ltd Gene therapies for Phenylketonuria
CN116478975B (zh) * 2023-06-16 2023-09-01 苏州优信合生技术有限公司 高活性苯丙氨酸解氨酶突变体及其表达菌株
WO2025106759A1 (en) 2023-11-17 2025-05-22 Biomarin Pharmaceutical Inc. Conjugates of phenylalanine ammonia-lyase and poegma and methods for their use

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Also Published As

Publication number Publication date
PT2152868E (pt) 2015-11-13
PL2152868T3 (pl) 2016-01-29
AR066716A1 (es) 2009-09-09
MX2009012453A (es) 2010-01-25
EA018443B1 (ru) 2013-08-30
LTPA2019517I1 (lt) 2019-10-25
KR20150038753A (ko) 2015-04-08
ES2551315T3 (es) 2015-11-18
IL202132A0 (en) 2010-06-16
EP2152868A1 (en) 2010-02-17
WO2008153776A1 (en) 2008-12-18
EP2657335A1 (en) 2013-10-30
EP2152868B1 (en) 2015-09-02
CY2019039I1 (el) 2020-05-29
HRP20151268T1 (hr) 2015-12-18
CN101842482A (zh) 2010-09-22
KR101603796B1 (ko) 2016-03-17
BRPI0811267A2 (pt) 2014-10-07
BRPI0811267B8 (pt) 2021-05-25
HUS1900049I1 (hu) 2019-11-28
LTC2152868I2 (lt) 2020-09-25
AR110834A2 (es) 2019-05-08
LUC00133I1 (nl) 2019-10-16
HUE025784T2 (en) 2016-05-30
KR20100024437A (ko) 2010-03-05
CA2687450C (en) 2019-03-26
WO2008153776A8 (en) 2009-07-30
PE20090315A1 (es) 2009-03-19
MY151413A (en) 2014-05-30
LUC00133I2 (nl) 2020-07-16
CY2019039I2 (el) 2020-05-29
NL301011I2 (nl) 2020-05-13
SI2152868T1 (sl) 2015-12-31
JP5670183B2 (ja) 2015-02-18
AU2008263190A1 (en) 2008-12-18
AU2008263190B2 (en) 2014-04-17
JP2010529835A (ja) 2010-09-02
US20080008695A1 (en) 2008-01-10
CA2687450A1 (en) 2008-12-18
BRPI0811267B1 (pt) 2020-11-10
NO2019037I1 (no) 2019-10-16
HK1135141A1 (zh) 2010-05-28
DK2152868T3 (en) 2015-11-16
EA200970980A1 (ru) 2010-04-30
US7534595B2 (en) 2009-05-19
CL2008001497A1 (es) 2009-01-09
TWI418633B (zh) 2013-12-11
CY1116894T1 (el) 2017-04-05
TW200902052A (en) 2009-01-16
CN101842482B (zh) 2014-10-22
IL202132A (en) 2017-06-29

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