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HUP0105102A3 - Heterocyclic derivatives as inhibitors of factor xa and pharmaceutical compositions containing them - Google Patents

Heterocyclic derivatives as inhibitors of factor xa and pharmaceutical compositions containing them

Info

Publication number
HUP0105102A3
HUP0105102A3 HU0105102A HUP0105102A HUP0105102A3 HU P0105102 A3 HUP0105102 A3 HU P0105102A3 HU 0105102 A HU0105102 A HU 0105102A HU P0105102 A HUP0105102 A HU P0105102A HU P0105102 A3 HUP0105102 A3 HU P0105102A3
Authority
HU
Hungary
Prior art keywords
inhibitors
factor
pharmaceutical compositions
compositions containing
heterocyclic derivatives
Prior art date
Application number
HU0105102A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HUP0105102A2 publication Critical patent/HUP0105102A2/hu
Publication of HUP0105102A3 publication Critical patent/HUP0105102A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0105102A 1999-02-11 2000-02-08 Heterocyclic derivatives as inhibitors of factor xa and pharmaceutical compositions containing them HUP0105102A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9902989.4A GB9902989D0 (en) 1999-02-11 1999-02-11 Heterocyclic derivatives

Publications (2)

Publication Number Publication Date
HUP0105102A2 HUP0105102A2 (hu) 2002-05-29
HUP0105102A3 true HUP0105102A3 (en) 2003-01-28

Family

ID=10847476

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0105102A HUP0105102A3 (en) 1999-02-11 2000-02-08 Heterocyclic derivatives as inhibitors of factor xa and pharmaceutical compositions containing them

Country Status (24)

Country Link
US (1) US6723723B1 (hu)
EP (1) EP1150974B1 (hu)
JP (1) JP2002536443A (hu)
KR (1) KR20010102072A (hu)
AT (1) ATE223402T1 (hu)
AU (1) AU757738B2 (hu)
BR (1) BR0008130A (hu)
CA (1) CA2362392A1 (hu)
CZ (1) CZ20012867A3 (hu)
DE (1) DE60000410T2 (hu)
DK (1) DK1150974T3 (hu)
ES (1) ES2181637T3 (hu)
GB (1) GB9902989D0 (hu)
HU (1) HUP0105102A3 (hu)
IL (1) IL144792A0 (hu)
NO (1) NO20013921L (hu)
NZ (1) NZ513350A (hu)
PL (1) PL349220A1 (hu)
PT (1) PT1150974E (hu)
RU (1) RU2226193C2 (hu)
SK (1) SK11462001A3 (hu)
TR (1) TR200102306T2 (hu)
WO (1) WO2000047573A1 (hu)
ZA (1) ZA200106337B (hu)

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IL115420A0 (en) 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
TWI288745B (en) 2000-04-05 2007-10-21 Daiichi Seiyaku Co Ethylenediamine derivatives
WO2003000657A1 (en) 2001-06-20 2003-01-03 Daiichi Pharmaceutical Co., Ltd. Diamine derivatives
DK1569912T3 (en) 2002-12-03 2015-06-29 Pharmacyclics Inc 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors.
JPWO2006109817A1 (ja) * 2005-04-06 2008-11-20 萬有製薬株式会社 １，４−置換ピペラジン誘導体
JP5214096B2 (ja) * 2005-06-17 2013-06-19 富士フイルムファインケミカルズ株式会社 新規なビピリジン誘導体
US20220380478A1 (en) 2019-07-01 2022-12-01 Tonix Pharma Holdings Limited Anti-cd154 antibodies and uses thereof
EP4274587A1 (en) 2021-01-06 2023-11-15 Tonix Pharma Limited Methods of inducing immune tolerance with modified anti-cd154 antibodies
WO2025248134A1 (en) 2024-05-31 2025-12-04 Tonix Pharma Limited Treatment methods comprising administration of modified cd154 antibodies

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Also Published As

Publication number Publication date
DK1150974T3 (da) 2002-12-02
NZ513350A (en) 2003-01-31
DE60000410D1 (de) 2002-10-10
NO20013921D0 (no) 2001-08-10
GB9902989D0 (en) 1999-03-31
EP1150974A1 (en) 2001-11-07
IL144792A0 (en) 2002-06-30
PT1150974E (pt) 2003-01-31
PL349220A1 (en) 2002-07-01
ATE223402T1 (de) 2002-09-15
DE60000410T2 (de) 2003-06-05
NO20013921L (no) 2001-10-10
AU757738B2 (en) 2003-03-06
TR200102306T2 (tr) 2001-12-21
WO2000047573A1 (en) 2000-08-17
KR20010102072A (ko) 2001-11-15
AU2447000A (en) 2000-08-29
ES2181637T3 (es) 2003-03-01
BR0008130A (pt) 2002-02-05
HUP0105102A2 (hu) 2002-05-29
CZ20012867A3 (cs) 2001-10-17
JP2002536443A (ja) 2002-10-29
CA2362392A1 (en) 2000-08-17
ZA200106337B (en) 2002-11-01
RU2226193C2 (ru) 2004-03-27
EP1150974B1 (en) 2002-09-04
US6723723B1 (en) 2004-04-20
SK11462001A3 (sk) 2001-12-03

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees