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HUP0100252A1 - Eljárás 1,3-diolok előállítására - Google Patents

Eljárás 1,3-diolok előállítására

Info

Publication number
HUP0100252A1
HUP0100252A1 HU0100252A HUP0100252A HUP0100252A1 HU P0100252 A1 HUP0100252 A1 HU P0100252A1 HU 0100252 A HU0100252 A HU 0100252A HU P0100252 A HUP0100252 A HU P0100252A HU P0100252 A1 HUP0100252 A1 HU P0100252A1
Authority
HU
Hungary
Prior art keywords
compound
general formula
formula
iii
reaction mixture
Prior art date
Application number
HU0100252A
Other languages
English (en)
Inventor
Robert Lee Bosch
Richard Joseph Mccabe
Thomas Norman Nanninga
Robert Joseph Stahl
Original Assignee
Warner-Lambert Export Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Export Ltd. filed Critical Warner-Lambert Export Ltd.
Publication of HUP0100252A1 publication Critical patent/HUP0100252A1/hu
Publication of HUP0100252A3 publication Critical patent/HUP0100252A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • C07C255/20—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00—Formation or introduction of functional groups containing oxygen
    • C07B41/02—Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • C07C255/21—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

A találmány tárgya eljárás (I) általános képletű vegyületekelőállítására, amelynek során (a) lépés: egy (II) általános képletűvegyületet vagy egy (III) általános képletű vegyületet - ahol aképletekben R és R1 jelentése a fentiekben meghatározott- oldószerbenegy trialkil-boránnal vagy egy dialkil-alkoxi-boránnal, vagy egy egytrialkil-borán és egy dialkil-alkoxi-borán keverékével reagáltatnak;(b) lépés: körülbelül -110 °C és körülbelül -50 °C közöttihőmérséklet-tartományban a reakciókeverékhez hozzáadnak egy alkálifém-hidridet; (c) lépés: a reakciókeveréket desztillációval betöményítveegy (I) általános képletű vegyületet és egy alkil-boránokat tartalmazódesztillátumot nyernek; és (d) lépés: további (I) általános képletűvegyület előállításához a (c) lépésben kapott, visszanyert alkil-boránokat tartalmazó desztillátummal további (II) vagy (III) általánosképletű vegyületet reagáltatnak, és megismétlik a (b) és (c) lépést. Ó
HU0100252A 1997-12-19 1998-12-02 Process for the synthesis of 1,3-diols HUP0100252A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6819397P 1997-12-19 1997-12-19
PCT/US1998/025493 WO1999032434A1 (en) 1997-12-19 1998-12-02 Process for the synthesis of 1,3-diols

Publications (2)

Publication Number Publication Date
HUP0100252A1 true HUP0100252A1 (hu) 2001-07-30
HUP0100252A3 HUP0100252A3 (en) 2002-12-28

Family

ID=22081016

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0100252A HUP0100252A3 (en) 1997-12-19 1998-12-02 Process for the synthesis of 1,3-diols

Country Status (31)

Country Link
US (4) US6433213B1 (hu)
EP (1) EP1054860B1 (hu)
JP (1) JP2001526256A (hu)
KR (2) KR100668575B1 (hu)
AR (1) AR014943A1 (hu)
AT (1) ATE360608T1 (hu)
AU (1) AU755543B2 (hu)
BR (1) BR9813760A (hu)
CA (1) CA2305618C (hu)
CO (1) CO4990941A1 (hu)
CU (1) CU22939A3 (hu)
CY (1) CY1106612T1 (hu)
DE (1) DE69837681T2 (hu)
DK (1) DK1054860T3 (hu)
ES (1) ES2284219T3 (hu)
GT (2) GT199800197A (hu)
HN (1) HN1998000187A (hu)
HU (1) HUP0100252A3 (hu)
IL (1) IL135562A (hu)
IS (1) IS5447A (hu)
MY (1) MY118726A (hu)
NO (1) NO20003139D0 (hu)
NZ (1) NZ504346A (hu)
PA (1) PA8464901A1 (hu)
PE (1) PE20000136A1 (hu)
PL (1) PL193678B1 (hu)
PT (1) PT1054860E (hu)
SV (1) SV1998000153A (hu)
TW (1) TW444000B (hu)
WO (1) WO1999032434A1 (hu)
ZA (1) ZA9811586B (hu)

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Also Published As

Publication number Publication date
HN1998000187A (es) 1999-10-22
AU755543B2 (en) 2002-12-12
HUP0100252A3 (en) 2002-12-28
ZA9811586B (en) 1999-06-17
PA8464901A1 (es) 2000-05-24
PE20000136A1 (es) 2000-03-11
NZ504346A (en) 2001-11-30
SV1998000153A (es) 1999-09-30
AR014943A1 (es) 2001-04-11
JP2001526256A (ja) 2001-12-18
NO20003139L (no) 2000-06-16
BR9813760A (pt) 2000-10-03
AU1707499A (en) 1999-07-12
CO4990941A1 (es) 2000-12-26
DE69837681D1 (de) 2007-06-06
IL135562A0 (en) 2001-05-20
US7232915B2 (en) 2007-06-19
KR20060080941A (ko) 2006-07-11
IL135562A (en) 2005-08-31
PL193678B1 (pl) 2007-03-30
US20050197500A1 (en) 2005-09-08
PL341294A1 (en) 2001-04-09
US20040006231A1 (en) 2004-01-08
KR100681366B1 (ko) 2007-02-12
MY118726A (en) 2005-01-31
KR20010033315A (ko) 2001-04-25
TW444000B (en) 2001-07-01
CY1106612T1 (el) 2012-01-25
ES2284219T3 (es) 2007-11-01
PT1054860E (pt) 2007-06-22
WO1999032434A1 (en) 1999-07-01
IS5447A (is) 2000-04-14
GT199800197A (es) 2000-06-06
EP1054860B1 (en) 2007-04-25
GT199800197AA (es) 2000-06-06
CU22939A3 (es) 2004-04-13
CA2305618C (en) 2004-08-17
NO20003139D0 (no) 2000-06-16
KR100668575B1 (ko) 2007-01-17
ATE360608T1 (de) 2007-05-15
CA2305618A1 (en) 1999-07-01
DK1054860T3 (da) 2007-07-02
US6433213B1 (en) 2002-08-13
US6596879B2 (en) 2003-07-22
EP1054860A1 (en) 2000-11-29
US6962994B2 (en) 2005-11-08
US20020161021A1 (en) 2002-10-31
DE69837681T2 (de) 2008-01-10

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