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HUP0004669A1 - Gyógyászati készítmények - Google Patents

Gyógyászati készítmények

Info

Publication number
HUP0004669A1
HUP0004669A1 HU0004669A HUP0004669A HUP0004669A1 HU P0004669 A1 HUP0004669 A1 HU P0004669A1 HU 0004669 A HU0004669 A HU 0004669A HU P0004669 A HUP0004669 A HU P0004669A HU P0004669 A1 HUP0004669 A1 HU P0004669A1
Authority
HU
Hungary
Prior art keywords
methyl
core material
pharmaceutical compositions
layer
pellets
Prior art date
Application number
HU0004669A
Other languages
English (en)
Inventor
Susan Jane Corvari
Joseph Richard Creekmore
Original Assignee
Astrazeneca Uk Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Ltd. filed Critical Astrazeneca Uk Ltd.
Publication of HUP0004669A1 publication Critical patent/HUP0004669A1/hu
Publication of HUP0004669A3 publication Critical patent/HUP0004669A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A találmány pelletek sokaságából álló gyógyászati készítményrevonatkozik, ahol az egyedi pelletek a) maganyagot, b) a maganyagotkörülvevő réteget tartalmaznak, amely réteg bl) más fizikai formáktóllényegében mentes amorf zafirlukastot, és b2) adott esetben egy vagytöbb más gyógyászatilag alkalmazható komponenst tartalmaz. Azafirlukast - kémiai nevén N-{4-[5-(ciklopentil-oxi-karbonil)-aminő-l-metil-indol-3-il-metil]-3-metoxi-benzoil}-2-metil ben- zol - ismertleukotrién-antagonista hatóanyag. Ó
HU0004669A 1997-12-18 1998-12-15 Pharmaceutical compositions HUP0004669A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726735.5A GB9726735D0 (en) 1997-12-18 1997-12-18 Pharmaceutical compositions
PCT/GB1998/003765 WO1999032082A2 (en) 1997-12-18 1998-12-15 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
HUP0004669A1 true HUP0004669A1 (hu) 2001-08-28
HUP0004669A3 HUP0004669A3 (en) 2005-03-29

Family

ID=10823809

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004669A HUP0004669A3 (en) 1997-12-18 1998-12-15 Pharmaceutical compositions

Country Status (30)

Country Link
US (1) US6399104B1 (hu)
EP (1) EP1041966B1 (hu)
JP (1) JP2001526206A (hu)
KR (1) KR20010033206A (hu)
CN (1) CN1282244A (hu)
AR (1) AR017884A1 (hu)
AT (1) ATE243999T1 (hu)
AU (1) AU744326C (hu)
BR (1) BR9813666A (hu)
CA (1) CA2313163A1 (hu)
DE (1) DE69816124T2 (hu)
DK (1) DK1041966T3 (hu)
EE (1) EE04260B1 (hu)
ES (1) ES2202915T3 (hu)
GB (1) GB9726735D0 (hu)
HU (1) HUP0004669A3 (hu)
ID (1) ID25857A (hu)
IL (1) IL136501A0 (hu)
IN (1) IN191311B (hu)
MY (1) MY133096A (hu)
NO (1) NO20003141L (hu)
NZ (1) NZ504566A (hu)
PL (1) PL341736A1 (hu)
PT (1) PT1041966E (hu)
RU (1) RU2205006C2 (hu)
SK (1) SK9402000A3 (hu)
TR (1) TR200001713T2 (hu)
UA (1) UA62991C2 (hu)
WO (1) WO1999032082A2 (hu)
ZA (1) ZA9811532B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO319624B1 (no) 2003-09-15 2005-09-05 Trouw Internat Bv Fiskefôr for laksefisk i ferskvann og anvendelse av slikt fôr.
US20050113410A1 (en) * 2003-11-03 2005-05-26 Mark Tawa Pharmaceutical salts of zafirlukast
DE102006006532B4 (de) * 2006-02-10 2007-11-08 Biogenerics Pharma Gmbh Pharmazeutische Zubereitung
JPWO2008117814A1 (ja) * 2007-03-26 2010-07-15 帝國製薬株式会社 大腸送達用経口製剤
US20090012146A1 (en) * 2007-07-02 2009-01-08 Giridhar Reddy Buggana Solubility-enhanced pharmaceutical compositions comprising zafirlukast
BR112019015721A2 (pt) 2017-01-30 2020-03-24 Western New England University Inibidores de tiol isomerases e uso dos mesmos
CN107714694A (zh) * 2017-11-01 2018-02-23 天津国际生物医药联合研究院 扎鲁司特在抗结核分枝杆菌感染中的应用
US12403122B2 (en) 2021-05-19 2025-09-02 Quercis Pharma AG Method for treating amyotrophic lateral sclerosis using quercetin-containing compositions
WO2023214391A1 (en) 2022-05-06 2023-11-09 Quercis Pharma AG Method for treating cancers and neurological diseases using quercetin-containing compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607294D0 (en) * 1985-04-17 1986-04-30 Ici America Inc Heterocyclic amide derivatives
IL100091A (en) * 1990-12-12 1998-08-16 Zeneca Ltd Pharmaceutical compositions containing a physical form of n-[4-[5-(cyclopentyloxycarbonyl)amino-1-methyl indol-3-yl-methyl]-2-methylbenzenesulpho-namide and process for their preparation
GB9027018D0 (en) * 1990-12-12 1991-01-30 Ici Plc Heterocyclic compounds
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents

Also Published As

Publication number Publication date
AU1571199A (en) 1999-07-12
RU2205006C2 (ru) 2003-05-27
CA2313163A1 (en) 1999-07-01
ID25857A (id) 2000-11-09
DE69816124D1 (de) 2003-08-07
US6399104B1 (en) 2002-06-04
DE69816124T2 (de) 2004-05-06
MY133096A (en) 2007-10-31
WO1999032082A3 (en) 1999-09-16
NO20003141D0 (no) 2000-06-16
NZ504566A (en) 2002-10-25
TR200001713T2 (tr) 2000-10-23
KR20010033206A (ko) 2001-04-25
EP1041966B1 (en) 2003-07-02
IL136501A0 (en) 2001-06-14
ATE243999T1 (de) 2003-07-15
PL341736A1 (en) 2001-05-07
EE200000330A (et) 2001-08-15
GB9726735D0 (en) 1998-02-18
NO20003141L (no) 2000-06-16
WO1999032082A2 (en) 1999-07-01
EP1041966A2 (en) 2000-10-11
UA62991C2 (en) 2004-01-15
IN191311B (hu) 2003-11-22
DK1041966T3 (da) 2003-10-06
AU744326B2 (en) 2002-02-21
ZA9811532B (en) 1999-06-18
HUP0004669A3 (en) 2005-03-29
SK9402000A3 (en) 2001-01-18
JP2001526206A (ja) 2001-12-18
ES2202915T3 (es) 2004-04-01
AU744326C (en) 2002-11-07
PT1041966E (pt) 2003-11-28
EE04260B1 (et) 2004-04-15
AR017884A1 (es) 2001-10-24
BR9813666A (pt) 2000-10-10
CN1282244A (zh) 2001-01-31

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