HU0000283D0 - New process for the production of medicine industrial product - Google Patents
New process for the production of medicine industrial productInfo
- Publication number
- HU0000283D0 HU0000283D0 HU0000283A HUP0000283A HU0000283D0 HU 0000283 D0 HU0000283 D0 HU 0000283D0 HU 0000283 A HU0000283 A HU 0000283A HU P0000283 A HUP0000283 A HU P0000283A HU 0000283 D0 HU0000283 D0 HU 0000283D0
- Authority
- HU
- Hungary
- Prior art keywords
- production
- new process
- industrial product
- medicine industrial
- formula
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- UZVGSSNIUNSOFA-UHFFFAOYSA-N dibenzofuran-1-carboxylic acid Chemical compound O1C2=CC=CC=C2C2=C1C=CC=C2C(=O)O UZVGSSNIUNSOFA-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- URKOMYMAXPYINW-UHFFFAOYSA-N quetiapine Chemical compound C1CN(CCOCCO)CCN1C1=NC2=CC=CC=C2SC2=CC=CC=C12 URKOMYMAXPYINW-UHFFFAOYSA-N 0.000 abstract 1
- 229960004431 quetiapine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0000283A HU227039B1 (en) | 2000-01-25 | 2000-01-25 | New process for the production of quetiapine and intermediates therefor |
| CZ20022463A CZ301236B6 (cs) | 2000-01-25 | 2001-01-24 | Zpusob prípravy chetiapinu a jeho meziproduktu |
| DK01904235T DK1252151T3 (da) | 2000-01-25 | 2001-01-24 | Fremgangsmåde til fremstilling af quetiapin og mellemprodukter dertil |
| DE2001602357 DE60102357T2 (de) | 2000-01-25 | 2001-01-24 | Verfahren zur herstellung von quetiapin und intermediate dafür |
| HR20020579A HRP20020579B1 (en) | 2000-01-25 | 2001-01-24 | A process for the preparation of quetiapine and intermediates thereof |
| AT01904235T ATE261949T1 (de) | 2000-01-25 | 2001-01-24 | Verfahren zur herstellung von quetiapin und intermediate dafür |
| AU32146/01A AU3214601A (en) | 2000-01-25 | 2001-01-24 | A process for the preparation of quetiapine and intermediates therefor |
| SK1060-2002A SK287171B6 (sk) | 2000-01-25 | 2001-01-24 | Spôsob prípravy chetiapínu a jeho medziproduktov |
| EP01904235A EP1252151B1 (en) | 2000-01-25 | 2001-01-24 | A process for the preparation of quetiapine and intermediates therefor |
| ES01904235T ES2217115T3 (es) | 2000-01-25 | 2001-01-24 | Procedimiento para la preparacion de quetiapina y de sus productos intermedios. |
| PCT/HU2001/000010 WO2001055125A1 (en) | 2000-01-25 | 2001-01-24 | A process for the preparation of quetiapine and intermediates therefor |
| PL355726A PL211338B1 (pl) | 2000-01-25 | 2001-01-24 | Sposób otrzymywania quetiapiny i związki przejściowe do tego procesu |
| RU2002122723/04A RU2258067C2 (ru) | 2000-01-25 | 2001-01-24 | Способ получения кветиапина и промежуточные соединения |
| UA2002086977A UA73547C2 (uk) | 2000-01-25 | 2001-01-24 | Спосіб одержання кветіапіну (варіанти) і проміжні сполуки |
| SI200130107T SI1252151T1 (en) | 2000-01-25 | 2001-01-24 | A process for the preparation of quetiapine and intermediates therefor |
| CNB2004100027829A CN1239487C (zh) | 2000-01-25 | 2001-01-24 | 制备奎替阿平的中间体及所述中间体的制备方法 |
| CNB018040993A CN1177839C (zh) | 2000-01-25 | 2001-01-24 | 奎替阿平及其中间体的制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0000283A HU227039B1 (en) | 2000-01-25 | 2000-01-25 | New process for the production of quetiapine and intermediates therefor |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| HU0000283D0 true HU0000283D0 (en) | 2000-03-28 |
| HUP0000283A2 HUP0000283A2 (hu) | 2002-04-29 |
| HUP0000283A3 HUP0000283A3 (en) | 2002-11-28 |
| HU227039B1 HU227039B1 (en) | 2010-05-28 |
Family
ID=89978038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0000283A HU227039B1 (en) | 2000-01-25 | 2000-01-25 | New process for the production of quetiapine and intermediates therefor |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1252151B1 (hu) |
| CN (2) | CN1239487C (hu) |
| AT (1) | ATE261949T1 (hu) |
| AU (1) | AU3214601A (hu) |
| CZ (1) | CZ301236B6 (hu) |
| DE (1) | DE60102357T2 (hu) |
| DK (1) | DK1252151T3 (hu) |
| ES (1) | ES2217115T3 (hu) |
| HR (1) | HRP20020579B1 (hu) |
| HU (1) | HU227039B1 (hu) |
| PL (1) | PL211338B1 (hu) |
| RU (1) | RU2258067C2 (hu) |
| SI (1) | SI1252151T1 (hu) |
| SK (1) | SK287171B6 (hu) |
| UA (1) | UA73547C2 (hu) |
| WO (1) | WO2001055125A1 (hu) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA76088C2 (en) | 1999-03-15 | 2006-07-17 | Axys Pharm Inc | N-cyanomethyl amides as cysteine protease inhibitors |
| IL156577A0 (en) | 2000-12-22 | 2004-01-04 | Axys Pharm Inc | Selective cathepsin s inhibitors and pharmaceutical compositions containing the same |
| US7030116B2 (en) | 2000-12-22 | 2006-04-18 | Aventis Pharmaceuticals Inc. | Compounds and compositions as cathepsin inhibitors |
| BR0212535A (pt) | 2001-09-14 | 2004-10-19 | Aventis Pharma Inc | Compostos e composições como inibidores de catepsina |
| US6977256B2 (en) | 2001-11-14 | 2005-12-20 | Aventis Pharmaceuticals Inc. | Compounds and compositions as cathepsin S inhibitors |
| EP1495008A1 (en) * | 2003-02-22 | 2005-01-12 | Teva Pharmaceutical Industries Limited | Synthesis of quetiapine and pharmaceutically acceptable salts thereof |
| EP2404615A1 (en) | 2003-04-23 | 2012-01-11 | Medarex, Inc. | Humanized antibodies to interferon alpha receptor-1 (IFNAR-1) |
| PL195728B1 (pl) * | 2003-07-18 | 2007-10-31 | Helm Ag | Sposób wytwarzania 11-(1-piperazynylo)dibenzo[b,f][1,4]tiazepiny |
| ES2223294B2 (es) * | 2003-08-08 | 2005-10-01 | Vita Cientifica, S.L. | Procedimiento de preparacion de un compuesto farmaceuticamente activo. |
| CA2538745A1 (en) | 2003-09-23 | 2005-03-31 | Fermion Oy | Preparation of quetiapine |
| ATE496038T1 (de) | 2003-09-23 | 2011-02-15 | Fermion Oy | Verfahren zur herstellung von quetiapin |
| KR101038389B1 (ko) * | 2004-06-23 | 2011-06-01 | 에스케이바이오팜 주식회사 | 11-(4-[2-(2-히드록시에톡시)에틸]-1-피페라지닐)-디벤조[b,f][1,4]티아제핀의 제조방법 |
| WO2006035293A1 (en) * | 2004-09-27 | 2006-04-06 | Ranbaxy Laboratories Limited | Polymorphic forms of quetiapine hemifumarate |
| WO2006056772A2 (en) * | 2004-11-23 | 2006-06-01 | Pliva Hrvatska D.O.O. | Salts of quetiapine |
| GB0425729D0 (en) * | 2004-11-23 | 2004-12-22 | Pliva Res & Dev Ltd | Heterocyclic compounds |
| ES2234447B1 (es) * | 2005-03-07 | 2006-03-01 | Union Quimico-Farmaceutica S.A. | Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina. |
| JP2008502707A (ja) | 2005-04-14 | 2008-01-31 | テバ ファーマシューティカル インダストリーズ リミティド | クエチアピンフマレートの調製方法 |
| US8044038B2 (en) | 2005-09-30 | 2011-10-25 | Fermion Oy | Crystallization process of quetiapine hemifumarate |
| SI2262486T1 (sl) | 2008-08-01 | 2013-04-30 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Sestavek kvetiapina |
| CN101676275B (zh) * | 2008-09-17 | 2014-05-07 | 北京德众万全药物技术开发有限公司 | 一种富马酸喹硫平的制备方法 |
| US20120071649A1 (en) | 2009-03-04 | 2012-03-22 | Ranbaxy Laboratories Limited | Process for the preparation of quetiapine fumarate |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2683147A (en) * | 1949-12-07 | 1954-07-06 | Geigy Ag J R | Quaternary ammonium compounds of bis-tertiary aminoalkoxy alkanes |
| CH422793A (de) * | 1961-07-20 | 1966-10-31 | Wander Ag Dr A | Verfahren zur Herstellung 11-basisch substituierter Dibenzo(b,f) (1,4)thiazepine |
| CH476753A (de) * | 1962-06-08 | 1969-08-15 | Wander Ag Dr A | Verfahren zur Herstellung von 11-basisch substituierter Dibenzo(b,f)(1,4)thiazepine |
| US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| US3560622A (en) * | 1967-10-13 | 1971-02-02 | American Cyanamid Co | Trifluoromethyl oxazepines,thiazepines and diazepines as anti-inflammatory agents |
-
2000
- 2000-01-25 HU HU0000283A patent/HU227039B1/hu not_active IP Right Cessation
-
2001
- 2001-01-24 EP EP01904235A patent/EP1252151B1/en not_active Expired - Lifetime
- 2001-01-24 SK SK1060-2002A patent/SK287171B6/sk not_active IP Right Cessation
- 2001-01-24 RU RU2002122723/04A patent/RU2258067C2/ru not_active IP Right Cessation
- 2001-01-24 ES ES01904235T patent/ES2217115T3/es not_active Expired - Lifetime
- 2001-01-24 AT AT01904235T patent/ATE261949T1/de active
- 2001-01-24 CN CNB2004100027829A patent/CN1239487C/zh not_active Expired - Fee Related
- 2001-01-24 SI SI200130107T patent/SI1252151T1/xx unknown
- 2001-01-24 DE DE2001602357 patent/DE60102357T2/de not_active Expired - Lifetime
- 2001-01-24 AU AU32146/01A patent/AU3214601A/en not_active Abandoned
- 2001-01-24 CN CNB018040993A patent/CN1177839C/zh not_active Expired - Fee Related
- 2001-01-24 HR HR20020579A patent/HRP20020579B1/xx not_active IP Right Cessation
- 2001-01-24 WO PCT/HU2001/000010 patent/WO2001055125A1/en not_active Ceased
- 2001-01-24 DK DK01904235T patent/DK1252151T3/da active
- 2001-01-24 CZ CZ20022463A patent/CZ301236B6/cs not_active IP Right Cessation
- 2001-01-24 UA UA2002086977A patent/UA73547C2/uk unknown
- 2001-01-24 PL PL355726A patent/PL211338B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1239487C (zh) | 2006-02-01 |
| PL355726A1 (en) | 2004-05-17 |
| HU227039B1 (en) | 2010-05-28 |
| HUP0000283A3 (en) | 2002-11-28 |
| EP1252151B1 (en) | 2004-03-17 |
| HUP0000283A2 (hu) | 2002-04-29 |
| DK1252151T3 (da) | 2004-07-12 |
| WO2001055125A1 (en) | 2001-08-02 |
| ATE261949T1 (de) | 2004-04-15 |
| CZ20022463A3 (cs) | 2002-10-16 |
| AU3214601A (en) | 2001-08-07 |
| CZ301236B6 (cs) | 2009-12-16 |
| CN1396916A (zh) | 2003-02-12 |
| DE60102357T2 (de) | 2005-01-13 |
| HRP20020579B1 (en) | 2005-08-31 |
| UA73547C2 (uk) | 2005-08-15 |
| SI1252151T1 (en) | 2004-08-31 |
| EP1252151A1 (en) | 2002-10-30 |
| RU2258067C2 (ru) | 2005-08-10 |
| SK10602002A3 (sk) | 2002-11-06 |
| RU2002122723A (ru) | 2004-01-10 |
| SK287171B6 (sk) | 2010-02-08 |
| ES2217115T3 (es) | 2004-11-01 |
| HRP20020579A2 (en) | 2004-08-31 |
| CN1537847A (zh) | 2004-10-20 |
| DE60102357D1 (de) | 2004-04-22 |
| PL211338B1 (pl) | 2012-05-31 |
| CN1177839C (zh) | 2004-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC9A | Change of name, address |
Owner name: EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDOE RESZV, HU Free format text: FORMER OWNER(S): EGIS GYOGYSZERGYAR RT., HU |
|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |