HRP20070357T3 - Thiazole derivatives and use thereof - Google Patents

Thiazole derivatives and use thereof

Info

Publication number: HRP20070357T3
Authority: HR; Croatia
Prior art keywords: alkyl; alkynyl; alkenyl; heteroaryl; aryl
Prior art date: 2004-01-12

Application number

HR20070357T

Other languages

English (en)

Croatian (hr)

Inventor

Quattropani Anna

Rueckle Thomas

Schwarz Matthias

Dorbais J�r�me

Sauer Wolfgang

Cleva Christophe

Desforges Gw�na�lle

Original Assignee

Applied Research Systems Ars Holding N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-12

Filing date

2005-01-11

Publication date

2007-10-31

2005-01-11 Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.

2007-10-31 Publication of HRP20070357T3 publication Critical patent/HRP20070357T3/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Neurology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Reproductive Health (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Pregnancy & Childbirth (AREA)
Psychiatry (AREA)
Psychology (AREA)
Transplantation (AREA)
Dermatology (AREA)
Gynecology & Obstetrics (AREA)
Hospice & Palliative Care (AREA)
Virology (AREA)
Endocrinology (AREA)

HR20070357T 2004-01-12 2005-01-11 Thiazole derivatives and use thereof HRP20070357T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP04100083		2004-01-12
PCT/EP2005/050102 WO2005068444A2 (en)	2004-01-12	2005-01-11	Thiazole derivatives and use thereof

Publications (1)

Publication Number	Publication Date
HRP20070357T3 true HRP20070357T3 (en)	2007-10-31

Family

ID=34778214

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20070357T HRP20070357T3 (en)	2004-01-12	2005-01-11	Thiazole derivatives and use thereof

Country Status (25)

Country	Link
US (2)	US8802861B2 (uk)
EP (1)	EP1709019B1 (uk)
JP (1)	JP5290524B2 (uk)
KR (1)	KR101260521B1 (uk)
CN (1)	CN1926121B (uk)
AT (1)	ATE369349T1 (uk)
AU (1)	AU2005205201B2 (uk)
BR (1)	BRPI0506749A (uk)
CA (1)	CA2551415C (uk)
CY (1)	CY1106921T1 (uk)
DE (1)	DE602005001931T2 (uk)
DK (1)	DK1709019T3 (uk)
EA (1)	EA012328B1 (uk)
ES (1)	ES2287896T3 (uk)
HR (1)	HRP20070357T3 (uk)
IL (1)	IL176764A (uk)
NO (1)	NO20063606L (uk)
NZ (1)	NZ548197A (uk)
PL (1)	PL1709019T3 (uk)
PT (1)	PT1709019E (uk)
RS (1)	RS50521B (uk)
SI (1)	SI1709019T1 (uk)
UA (1)	UA83099C2 (uk)
WO (1)	WO2005068444A2 (uk)
ZA (1)	ZA200605624B (uk)

Families Citing this family (29)

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TW200519106A (en)	2003-05-02	2005-06-16	Novartis Ag	Organic compounds
CN101083996A (zh) *	2004-10-28	2007-12-05	Irm责任有限公司	作为hedgehog途径调节剂的化合物和组合物
UA92489C2 (en) *	2005-05-24	2010-11-10	Лаборатуар Сероно С.А.	Thiazole derivatives and use thereof
EP1741709A1 (en) *	2005-06-28	2007-01-10	Sanofi-Aventis Deutschland GmbH	Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
ES2389062T3 (es)	2006-01-18	2012-10-22	Amgen, Inc	Compuestos de tiazol como inhibidores de proteína cinasa B (PKB)
US20100004277A1 (en) *	2006-01-26	2010-01-07	Foldrx Pharmaceuticals, Inc.	Compounds and methods for modulating protein trafficking
CA2677949C (en) *	2007-02-22	2016-02-09	Paul Anthony Worthington	Iminipyridine derivatives and their uses as microbiocides
EP2572712A3 (en)	2007-06-01	2013-11-20	The Trustees Of Princeton University	Treatment of viral infections by modulation of host cell metabolic pathways
AU2008276512A1 (en)	2007-07-17	2009-01-22	Amgen Inc.	Thiadiazole modulators of PKB
CA2692713A1 (en)	2007-07-17	2009-01-22	Amgen Inc.	Heterocyclic modulators of pkb
US8389736B2 (en)	2007-10-16	2013-03-05	The Regents Of The University Of California	Compounds having activity in correcting mutant-CFTR processing and uses thereof
EP2240475B1 (en) *	2007-12-20	2013-09-25	Novartis AG	Thiazole derivatives used as pi 3 kinase inhibitors
US20100298286A1 (en) *	2007-12-20	2010-11-25	Novartis Ag	Organic Compounds
UA104147C2 (uk)	2008-09-10	2014-01-10	Новартис Аг	Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
EA201200087A1 (ru)	2009-07-02	2012-07-30	Новартис Аг	2-карбоксамиды циклоаминомочевин, которые являются ингибиторами pi3k
US8293753B2 (en)	2009-07-02	2012-10-23	Novartis Ag	Substituted 2-carboxamide cycloamino ureas
WO2011048936A1 (ja) *	2009-10-19	2011-04-28	大正製薬株式会社	アミノチアゾール誘導体
US20120129842A1 (en)	2010-11-18	2012-05-24	Paul Francis Jackson	Bisthiazole inhibitors of pro-matrix metalloproteinase activation
US20120302573A1 (en)	2011-05-25	2012-11-29	Paul Francis Jackson	Methods of inhibiting pro matrix metalloproteinase activation
CA2840202A1 (en)	2011-06-29	2013-01-03	Janssen Pharmaceutica Nv	Crystal structure of the pro form of a matrix metalloproteinase and an allosteric processing inhibitor
JP6002764B2 (ja) *	2011-06-29	2016-10-05	ヤンセンファーマシューティカエヌ．ベー．	マトリックスメタロプロテアーゼのアロステリックなプロセシング阻害因子を使用する処置方法
JP6182136B2 (ja)	2011-06-29	2017-08-16	ヤンセンファーマシューティカエヌ．ベー．	マトリックスメタロプロテアーゼのアロステリックなプロセシング阻害因子を設計、選択及び／又は最適化するための方法
WO2015046193A1 (ja)	2013-09-25	2015-04-02	塩野義製薬株式会社	Ｔｒｐｖ４阻害活性を有する芳香族複素環式アミン誘導体
EP3052480B1 (en) *	2013-09-30	2020-11-11	The Texas A & M University System	Compositions associated with and methods of managing neutrophil movement
GB201705263D0 (en) *	2017-03-31	2017-05-17	Probiodrug Ag	Novel inhibitors
CN108570043A (zh) *	2018-06-20	2018-09-25	王延娇	一种化合物及其作为选择性pi3k抑制剂在治疗肿瘤中的应用
EP3811940B1 (en) *	2019-10-22	2023-05-10	Kemijski Institut	Substituted 4,5'-bithiazoles as inhibitors of the human dna topoisomerase ii
IL291418B2 (en)	2022-03-16	2024-05-01	Anima Biotech Inc	Substances that function as modulators of cMYC-mRNA translation and their uses for cancer treatment
WO2025151517A1 (en) *	2024-01-08	2025-07-17	Wavebreak Therapeutics Limited	Thiazole compounds, compositions and methods of treating disorders associated with missfolding of alpha-synuclein protein

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US4649146A (en)	1983-01-31	1987-03-10	Fujisawa Pharmaceutical Co., Ltd.	Thiazole derivatives and pharmaceutical composition comprising the same
SE9302332D0 (sv)	1993-07-06	1993-07-06	Ab Astra	New compounds
US6262096B1 (en) *	1997-11-12	2001-07-17	Bristol-Myers Squibb Company	Aminothiazole inhibitors of cyclin dependent kinases
JPH11209284A (ja)	1998-01-27	1999-08-03	Sagami Chem Res Center	骨形成促進剤
GB9823871D0 (en) *	1998-10-30	1998-12-23	Pharmacia & Upjohn Spa	2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
UA71971C2 (en) *	1999-06-04	2005-01-17	Agoron Pharmaceuticals Inc	Diaminothiazoles, composition based thereon, a method for modulation of protein kinases activity, a method for the treatment of diseases mediated by protein kinases
DE60112272T2 (de) *	2000-04-27	2006-05-24	Astellas Pharma Inc.	Imidazopyridin-derivate
JP2002053566A (ja) *	2000-08-11	2002-02-19	Japan Tobacco Inc	チアゾール化合物及びその医薬用途
ATE315555T1 (de)	2001-05-11	2006-02-15	Pfizer Prod Inc	Thiazolderivate und ihre verwendung als cdk- inhibitoren
TWI314928B (en) *	2002-02-28	2009-09-21	Novartis A	5-phenylthiazole derivatives and use as pi3 kinase inhibitors
CN101083996A (zh) *	2004-10-28	2007-12-05	Irm责任有限公司	作为hedgehog途径调节剂的化合物和组合物

2005
- 2005-01-11 EA EA200601242A patent/EA012328B1/ru not_active IP Right Cessation
- 2005-01-11 CN CN200580006639XA patent/CN1926121B/zh not_active Expired - Fee Related
- 2005-01-11 AT AT05701490T patent/ATE369349T1/de active
- 2005-01-11 PT PT05701490T patent/PT1709019E/pt unknown
- 2005-01-11 DK DK05701490T patent/DK1709019T3/da active
- 2005-01-11 ES ES05701490T patent/ES2287896T3/es not_active Expired - Lifetime
- 2005-01-11 NZ NZ548197A patent/NZ548197A/en not_active IP Right Cessation
- 2005-01-11 EP EP20050701490 patent/EP1709019B1/en not_active Expired - Lifetime
- 2005-01-11 US US10/585,635 patent/US8802861B2/en not_active Expired - Fee Related
- 2005-01-11 CA CA 2551415 patent/CA2551415C/en not_active Expired - Fee Related
- 2005-01-11 JP JP2006548315A patent/JP5290524B2/ja not_active Expired - Fee Related
- 2005-01-11 RS RSP20070410 patent/RS50521B/sr unknown
- 2005-01-11 AU AU2005205201A patent/AU2005205201B2/en not_active Ceased
- 2005-01-11 ZA ZA200605624A patent/ZA200605624B/en unknown
- 2005-01-11 HR HR20070357T patent/HRP20070357T3/xx unknown
- 2005-01-11 DE DE200560001931 patent/DE602005001931T2/de not_active Expired - Lifetime
- 2005-01-11 WO PCT/EP2005/050102 patent/WO2005068444A2/en not_active Ceased
- 2005-01-11 PL PL05701490T patent/PL1709019T3/pl unknown
- 2005-01-11 BR BRPI0506749-9A patent/BRPI0506749A/pt not_active IP Right Cessation
- 2005-01-11 SI SI200530042T patent/SI1709019T1/sl unknown
- 2005-11-01 UA UAA200607633A patent/UA83099C2/ru unknown
2006
- 2006-07-10 IL IL176764A patent/IL176764A/en not_active IP Right Cessation
- 2006-07-28 KR KR1020067015376A patent/KR101260521B1/ko not_active Expired - Fee Related
- 2006-08-09 NO NO20063606A patent/NO20063606L/no not_active Application Discontinuation
2007
- 2007-10-08 CY CY071101296T patent/CY1106921T1/el unknown
2014
- 2014-02-07 US US14/175,751 patent/US9150561B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE369349T1 (de)	2007-08-15
ES2287896T3 (es)	2007-12-16
CY1106921T1 (el)	2012-09-26
ZA200605624B (en)	2007-11-28
BRPI0506749A (pt)	2007-05-22
NO20063606L (no)	2006-10-12
CN1926121A (zh)	2007-03-07
DE602005001931T2 (de)	2008-04-24
WO2005068444A3 (en)	2005-09-09
AU2005205201B2 (en)	2011-05-12
KR101260521B1 (ko)	2013-05-06
US8802861B2 (en)	2014-08-12
DK1709019T3 (da)	2007-10-01
EP1709019A2 (en)	2006-10-11
JP2007517835A (ja)	2007-07-05
US9150561B2 (en)	2015-10-06
IL176764A (en)	2011-06-30
RS50521B (sr)	2010-05-07
US20090029998A1 (en)	2009-01-29
CN1926121B (zh)	2012-06-13
WO2005068444A2 (en)	2005-07-28
HK1103720A1 (zh)	2007-12-28
IL176764A0 (en)	2006-10-31
NZ548197A (en)	2010-06-25
AU2005205201A1 (en)	2005-07-28
SI1709019T1 (sl)	2007-10-31
EA012328B1 (ru)	2009-08-28
CA2551415A1 (en)	2005-07-28
KR20060128975A (ko)	2006-12-14
EP1709019B1 (en)	2007-08-08
CA2551415C (en)	2013-09-10
EA200601242A1 (ru)	2007-02-27
UA83099C2 (en)	2008-06-10
PL1709019T3 (pl)	2007-10-31
PT1709019E (pt)	2007-08-27
JP5290524B2 (ja)	2013-09-18
DE602005001931D1 (de)	2007-09-20
US20140228365A1 (en)	2014-08-14

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ATE526320T1 (de)	2011-10-15	Antagonisten des vanilloidrezeptors vom subtyp 1 (vr1), und anwendungen davon
CY1108880T1 (el)	2014-07-02	Παραγωγα καρβοξαμιδιου ως ανταγωνιστες μουσκαρινικου υποδοχεα
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UY29673A1 (es)	2007-02-28	Derivados sustituidos de 6-(4-clorofenil) tieno (3,2,d)- pirimidin- 4(3h)-ona y (1,2,3,)-triazin-4-(3h)-ona,composiciones farmaceuticas conteniéndolos, procesosde peparación y aplicaciones.
MX2016014239A (es)	2017-02-14	Composicion limpiadora.
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