HRP20041203A2 - Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof - Google Patents

Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof

Info

Publication number: HRP20041203A2
Authority: HR; Croatia
Prior art keywords: compounds; ring; production; medicaments containing; substituted diphenyl
Prior art date: 2002-06-19

Application number

HR20041203A

Inventor

Jaehne Gerhard

Frick Wendelin

Flohr Stefanie

Lindenschmidt Andreas

Glombik Heiner

Kramer Werner

Heuer Hubert

Schaefer Hans-Ludwig

Original Assignee

Aventis Pharma Deutschland Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-19

Filing date

2003-06-04

Publication date

2005-06-30

2003-06-04 Application filed by Aventis Pharma Deutschland Gmbh filed Critical Aventis Pharma Deutschland Gmbh

2005-06-30 Publication of HRP20041203A2 publication Critical patent/HRP20041203A2/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

HR20041203A 2002-06-19 2003-06-04 Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof HRP20041203A2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10227506A DE10227506A1 (en)	2002-06-19	2002-06-19	Ring-substituted diphenylazetidinones, processes for their preparation, pharmaceutical compositions containing them and their use
PCT/EP2003/005815 WO2004000804A1 (en)	2002-06-19	2003-06-04	Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof

Publications (1)

Publication Number	Publication Date
HRP20041203A2 true HRP20041203A2 (en)	2005-06-30

Family

ID=29719281

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20041203A HRP20041203A2 (en)	2002-06-19	2003-06-04	Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof

Country Status (30)

Country	Link
EP (1)	EP1517892B1 (en)
JP (1)	JP2005533072A (en)
CN (1)	CN1662493A (en)
AR (1)	AR039689A1 (en)
AT (1)	ATE478842T1 (en)
AU (1)	AU2003242616B2 (en)
BR (1)	BR0311940A (en)
CA (1)	CA2490109A1 (en)
DE (2)	DE10227506A1 (en)
EC (1)	ECSP045498A (en)
HN (1)	HN2003000183A (en)
HR (1)	HRP20041203A2 (en)
IL (1)	IL165791A0 (en)
MA (1)	MA27252A1 (en)
MX (1)	MXPA04012236A (en)
MY (1)	MY135850A (en)
NO (1)	NO20050073L (en)
NZ (1)	NZ537304A (en)
OA (1)	OA12868A (en)
PA (1)	PA8576001A1 (en)
PE (1)	PE20040577A1 (en)
PL (1)	PL372690A1 (en)
RS (1)	RS108504A (en)
RU (1)	RU2315754C2 (en)
SV (1)	SV2004001549A (en)
TN (1)	TNSN04255A1 (en)
TW (1)	TW200404774A (en)
UY (1)	UY27851A1 (en)
WO (1)	WO2004000804A1 (en)
ZA (1)	ZA200409381B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0215579D0 (en)	2002-07-05	2002-08-14	Astrazeneca Ab	Chemical compounds
US7447226B2 (en) *	2003-10-31	2008-11-04	International Business Machines Corporation	Methods and apparatus for continuous connectivity between mobile device and network using dynamic connection spreading
WO2005061452A1 (en)	2003-12-23	2005-07-07	Astrazeneca Ab	Diphenylazetidinone derivates possessing cholesterol absorption inhibitory activity
CA2589483C (en)	2004-12-03	2013-10-29	Schering Corporation	Substituted piperazines as cb1 antagonists
BRPI0609614A2 (en) *	2005-04-04	2010-04-20	Univ Pontificia Catolica Chile	use of ezetimibe in the prevention and treatment of biliary tree cholesterol lithiases
EP1902046B1 (en)	2005-06-20	2009-12-02	Schering Corporation	Piperidine derivatives useful as histamine h3 antagonists
SA06270191B1 (en)	2005-06-22	2010-03-29	استرازينيكا ايه بي	Novel 2-Azetidinone Derivatives as Cholesterol Absorption Inhibitors for the Treatment of Hyperlipidaemic Conditions
AR060623A1 (en)	2006-04-27	2008-07-02	Astrazeneca Ab	COMPOUNDS DERIVED FROM 2-AZETIDINONE AND A PREPARATION METHOD
JP2010500300A (en)	2006-08-08	2010-01-07	サノフィ−アベンティス	Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for their preparation, agents containing these compounds, and uses thereof
WO2008052658A1 (en) *	2006-11-02	2008-05-08	Sanofi-Aventis Deutschland Gmbh	Novel diphenylazetidinone substituted by piperazine-1-sulfonic acid having improved pharmacological properties
DE102007002260A1 (en)	2007-01-16	2008-07-31	Sanofi-Aventis	Use of substituted pyranonic acid derivatives for the preparation of medicaments for the treatment of the metabolic syndrome
EP2025674A1 (en)	2007-08-15	2009-02-18	sanofi-aventis	Substituted tetra hydro naphthalines, method for their manufacture and their use as drugs
DE102007063671A1 (en)	2007-11-13	2009-06-25	Sanofi-Aventis Deutschland Gmbh	New crystalline diphenylazetidinone hydrates, medicaments containing these compounds and their use
WO2010003624A2 (en)	2008-07-09	2010-01-14	Sanofi-Aventis	Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en)	2008-12-08	2010-06-17	Sanofi-Aventis	A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
CA2754384A1 (en)	2009-03-06	2010-09-10	Lipideon Biotechnology Ag	Pharmaceutical hypocholesterolemic compositions
CN101993403B (en)	2009-08-11	2012-07-11	浙江海正药业股份有限公司	Azetidinone compound and medical applications thereof
KR20120060207A (en)	2009-08-26	2012-06-11	사노피	Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
WO2011157827A1 (en)	2010-06-18	2011-12-22	Sanofi	Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8828994B2 (en)	2011-03-08	2014-09-09	Sanofi	Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120056A1 (en)	2011-03-08	2012-09-13	Sanofi	Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2766349B1 (en)	2011-03-08	2016-06-01	Sanofi	Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
US8828995B2 (en)	2011-03-08	2014-09-09	Sanofi	Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120055A1 (en)	2011-03-08	2012-09-13	Sanofi	Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5631365A (en) *	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US5656624A (en) *	1994-12-21	1997-08-12	Schering Corporation	4-[(heterocycloalkyl or heteroaromatic)-substituted phenyl]-2-azetidinones useful as hypolipidemic agents
ATE219495T1 (en) *	1995-10-31	2002-07-15	Schering Corp	SUGAR SUBSTITUTED 2-AZETIDINONE USABLE AS HYPOCHOLESTERDENIC DRUGS
DE10042447A1 (en) *	2000-08-29	2002-03-28	Aventis Pharma Gmbh	Vertebrate intestinal protein that absorbs cholesterol and use of this protein to identify inhibitors of intestinal cholesterol transport

2002
- 2002-06-19 DE DE10227506A patent/DE10227506A1/en not_active Withdrawn
2003
- 2003-01-17 HN HN2003000183A patent/HN2003000183A/en unknown
- 2003-06-02 SV SV2003001549A patent/SV2004001549A/en not_active Application Discontinuation
- 2003-06-04 AT AT03760591T patent/ATE478842T1/en active
- 2003-06-04 DE DE50313017T patent/DE50313017D1/en not_active Expired - Lifetime
- 2003-06-04 RS YUP-1085/04A patent/RS108504A/en unknown
- 2003-06-04 OA OA1200400330A patent/OA12868A/en unknown
- 2003-06-04 AU AU2003242616A patent/AU2003242616B2/en not_active Ceased
- 2003-06-04 MX MXPA04012236A patent/MXPA04012236A/en active IP Right Grant
- 2003-06-04 BR BR0311940-8A patent/BR0311940A/en not_active IP Right Cessation
- 2003-06-04 PL PL03372690A patent/PL372690A1/en not_active Application Discontinuation
- 2003-06-04 JP JP2004514660A patent/JP2005533072A/en not_active Abandoned
- 2003-06-04 HR HR20041203A patent/HRP20041203A2/en not_active Application Discontinuation
- 2003-06-04 NZ NZ537304A patent/NZ537304A/en unknown
- 2003-06-04 EP EP03760591A patent/EP1517892B1/en not_active Expired - Lifetime
- 2003-06-04 RU RU2005101091/04A patent/RU2315754C2/en not_active IP Right Cessation
- 2003-06-04 CA CA002490109A patent/CA2490109A1/en not_active Abandoned
- 2003-06-04 WO PCT/EP2003/005815 patent/WO2004000804A1/en not_active Ceased
- 2003-06-04 CN CN03814087XA patent/CN1662493A/en active Pending
- 2003-06-16 UY UY27851A patent/UY27851A1/en unknown
- 2003-06-17 AR ARP030102142A patent/AR039689A1/en unknown
- 2003-06-17 TW TW092116319A patent/TW200404774A/en unknown
- 2003-06-18 PE PE2003000613A patent/PE20040577A1/en not_active Application Discontinuation
- 2003-06-18 PA PA20038576001A patent/PA8576001A1/en unknown
- 2003-06-18 MY MYPI20032289A patent/MY135850A/en unknown
2004
- 2004-11-22 ZA ZA200409381A patent/ZA200409381B/en unknown
- 2004-12-08 MA MA27990A patent/MA27252A1/en unknown
- 2004-12-15 IL IL16579104A patent/IL165791A0/en unknown
- 2004-12-16 EC EC2004005498A patent/ECSP045498A/en unknown
- 2004-12-17 TN TNP2004000255A patent/TNSN04255A1/en unknown
2005
- 2005-01-06 NO NO20050073A patent/NO20050073L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
AR039689A1 (en)	2005-03-09
AU2003242616A1 (en)	2004-01-06
UY27851A1 (en)	2003-12-31
ATE478842T1 (en)	2010-09-15
TW200404774A (en)	2004-04-01
JP2005533072A (en)	2005-11-04
SV2004001549A (en)	2004-03-19
ZA200409381B (en)	2006-05-31
NO20050073L (en)	2005-01-06
DE10227506A1 (en)	2004-01-08
MA27252A1 (en)	2005-03-01
TNSN04255A1 (en)	2007-03-12
RU2005101091A (en)	2005-07-10
CN1662493A (en)	2005-08-31
PA8576001A1 (en)	2004-02-07
RS108504A (en)	2007-02-05
DE50313017D1 (en)	2010-10-07
EP1517892B1 (en)	2010-08-25
PE20040577A1 (en)	2004-10-11
MXPA04012236A (en)	2005-02-25
PL372690A1 (en)	2005-07-25
IL165791A0 (en)	2006-01-15
NZ537304A (en)	2005-10-28
ECSP045498A (en)	2005-03-10
WO2004000804A1 (en)	2003-12-31
MY135850A (en)	2008-07-31
AU2003242616B2 (en)	2008-12-11
EP1517892A1 (en)	2005-03-30
RU2315754C2 (en)	2008-01-27
OA12868A (en)	2006-09-15
BR0311940A (en)	2005-04-05
CA2490109A1 (en)	2003-12-31
HN2003000183A (en)	2003-08-01

Publication	Publication Date	Title
HRP20041203A2 (en)	2005-06-30	Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof
AU2003257465A1 (en)	2004-02-23	Substituted diaryl heterocycles, method for the production and use thereof as medicaments
IL156552A0 (en)	2004-01-04	Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use
HRP20030501A2 (en)	2005-04-30	Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use
PL375344A1 (en)	2005-11-28	Novel carboxamide compounds having an mch-antagonistic effect, medicaments containing said compounds, and methods for the production thereof
AU2002219173A1 (en)	2002-09-05	Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use
PL378065A1 (en)	2006-02-20	Substituted n-arylheterocycles, method for production and use thereof as medicaments
IL191926A0 (en)	2008-12-29	Novel thiophenylglycoside derivatives, methods for production thereof, medicaments comprising said compounds and use thereof
IL180874A0 (en)	2007-07-04	Substituted, bicyclic 8-pyrrolidinoxanthines, method for the production thereof and their use as medicaments
IL162669A0 (en)	2005-11-20	Antichlinergic agents, method for producing the same and use thereof as medicaments
HRP20041201A2 (en)	2005-08-31	Diphenyl azetidinones substituted by acidic groups, method for their production, medicaments containing said compounds and use thereof
IL191988A0 (en)	2008-12-29	Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for the production thereof
AU2003226806A1 (en)	2003-11-03	Bicyclic heterocycles, medicaments containing these compounds, their use, and method for the production thereof
PL376399A1 (en)	2005-12-27	Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same
SI1613589T1 (en)	2008-06-30	Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter
IL162316A0 (en)	2005-11-20	Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use thereof as medicaments, in addition t
ZA200506422B (en)	2007-02-28	Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use of the same as medicaments, and medicament containing such compounds
PL371784A1 (en)	2005-06-27	Pentafluorosulfanyl-benzoylguanidine, method for the production thereof and its utilization as medicament or diagnostic agent and medicament containing same
HRP20041153A2 (en)	2005-06-30	Substituted thiophenes, method for the production thereof, their use as a medicament or diagnostic reagent, and a medicament containing the same
IL173918A0 (en)	2006-07-05	Substituted thienoimidazoles, method for production and use thereof as medicament or diagnostic and medicaments comprising the same
IL175237A (en)	2010-12-30	Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments and medicaments containing the same
HUP0500119A3 (en)	2008-04-28	Depot medicament, carrier materials for depot medicaments, and method for the production thereof
AU2003216893A1 (en)	2003-10-13	Phenethylacrylamide, methods for the production thereof and agents containing the same
SI1560826T1 (en)	2006-08-31	Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same
IL175897A0 (en)	2006-10-05	6-(2-fluoride-4-alkoxyphenyl)-triazolopyrimidine, method for the production and use thereof against harmful fungus and agents containing said product

Legal Events

Date	Code	Title	Description
2005-06-30	A1OB	Publication of a patent application
2005-12-27	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2006-02-09	PNAN	Change of the applicant name, address/residence	Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, DE
2009-06-02	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20090602 Year of fee payment: 7
2010-12-06	OBST	Application withdrawn