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HRP20040157A2 - Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride - Google Patents

Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride Download PDF

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Publication number
HRP20040157A2
HRP20040157A2 HR20040157A HRP20040157A HRP20040157A2 HR P20040157 A2 HRP20040157 A2 HR P20040157A2 HR 20040157 A HR20040157 A HR 20040157A HR P20040157 A HRP20040157 A HR P20040157A HR P20040157 A2 HRP20040157 A2 HR P20040157A2
Authority
HR
Croatia
Prior art keywords
lercanidipine hydrochloride
mol
solvate
lercanidipine
methyl
Prior art date
Application number
HR20040157A
Other languages
English (en)
Croatian (hr)
Inventor
Amedeo Leonardi
Gianluca De Iasi
Fausto Bonifacio
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Publication of HRP20040157A2 publication Critical patent/HRP20040157A2/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR20040157A 2001-08-06 2002-08-05 Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride HRP20040157A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001MI001727A ITMI20011727A1 (it) 2001-08-06 2001-08-06 Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi
PCT/EP2002/008700 WO2003014085A1 (en) 2001-08-06 2002-08-05 Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride

Publications (1)

Publication Number Publication Date
HRP20040157A2 true HRP20040157A2 (en) 2004-08-31

Family

ID=11448246

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040157A HRP20040157A2 (en) 2001-08-06 2002-08-05 Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride

Country Status (21)

Country Link
EP (1) EP1423367B1 (es)
JP (1) JP2005502648A (es)
KR (1) KR100912664B1 (es)
CN (1) CN100494175C (es)
AR (1) AR037230A1 (es)
AT (1) ATE294162T1 (es)
AU (1) AU2002331390B2 (es)
BR (1) BR0211738A (es)
DE (1) DE60203919D1 (es)
EA (1) EA200400279A1 (es)
ES (1) ES2209684T1 (es)
HR (1) HRP20040157A2 (es)
HU (1) HUP0401161A3 (es)
IL (2) IL153916A0 (es)
IT (1) ITMI20011727A1 (es)
MX (1) MXPA04001073A (es)
NO (1) NO20040479L (es)
PE (1) PE20030350A1 (es)
PL (1) PL369449A1 (es)
UY (1) UY27409A1 (es)
WO (1) WO2003014085A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100651212B1 (ko) 2004-10-27 2006-12-01 제일약품주식회사 무정형 레르카니디핀의 제조방법
AR052918A1 (es) 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
EP1940790B1 (en) 2005-09-16 2015-09-02 Glenmark Pharmaceuticals Limited Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof
CN101868442A (zh) * 2007-03-05 2010-10-20 阿克塔维什集团Ptc公司 盐酸乐卡地平多晶型物和1,1,n-三甲基-n-(3,3-二苯基丙基)-2-氨基乙酰醋酸乙酯的改进制法
WO2008136394A1 (ja) * 2007-04-27 2008-11-13 Ajinomoto Co., Inc. ラクタム化合物の製造方法及びその製造中間体
SI2585051T2 (sl) 2010-06-23 2020-07-31 Krka, D.D., Novo Mesto Farmacevtske oralne odmerne oblike,ki obsegajo lerkanidipin in enalapril in njune farmacevtsko sprejemljive soli
SI2654729T1 (sl) 2010-12-24 2016-08-31 Krka, D.D., Novo Mesto Homogene farmacevtske oralne dozirne oblike, ki obsegajo lerkanidipin in enalapril ali njune farmacevtsko sprejemljive soli skupaj z organsko kislino

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
US5767136A (en) 1995-05-12 1998-06-16 Recordati, S.A. Chemical And Pharmaceutical Company 1,4-Dihydropyridines useful for prevention or reduction of atherosclerotic lesions on arterial walls

Also Published As

Publication number Publication date
CN100494175C (zh) 2009-06-03
IL153916A0 (en) 2003-07-31
CN1538958A (zh) 2004-10-20
PE20030350A1 (es) 2003-06-06
HUP0401161A2 (hu) 2004-09-28
WO2003014085A1 (en) 2003-02-20
UY27409A1 (es) 2003-03-31
ES2209684T1 (es) 2004-07-01
KR100912664B1 (ko) 2009-08-17
JP2005502648A (ja) 2005-01-27
IL153916A (en) 2008-07-08
EP1423367A1 (en) 2004-06-02
PL369449A1 (en) 2005-04-18
ATE294162T1 (de) 2005-05-15
ITMI20011727A0 (it) 2001-08-06
MXPA04001073A (es) 2005-02-17
HUP0401161A3 (en) 2009-04-28
NO20040479L (no) 2004-02-03
KR20040030932A (ko) 2004-04-09
BR0211738A (pt) 2004-09-28
AU2002331390B2 (en) 2008-06-05
EA200400279A1 (ru) 2004-06-24
EP1423367B1 (en) 2005-04-27
DE60203919D1 (de) 2005-06-02
ITMI20011727A1 (it) 2003-02-06
AR037230A1 (es) 2004-11-03

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