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HK1221726A1 - 炎性疾病中的il-18结合蛋白(il-18bp) - Google Patents

炎性疾病中的il-18结合蛋白(il-18bp) Download PDF

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Publication number
HK1221726A1
HK1221726A1 HK16109981.4A HK16109981A HK1221726A1 HK 1221726 A1 HK1221726 A1 HK 1221726A1 HK 16109981 A HK16109981 A HK 16109981A HK 1221726 A1 HK1221726 A1 HK 1221726A1
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HK
Hong Kong
Prior art keywords
binding protein
inflammatory diseases
present
indications
disorders
Prior art date
Application number
HK16109981.4A
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English (en)
Other versions
HK1221726B (zh
Inventor
Andrea Pfeifer
Greg Del Val
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Ab2 Bio Sa
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Publication date
Application filed by Ab2 Bio Sa filed Critical Ab2 Bio Sa
Publication of HK1221726A1 publication Critical patent/HK1221726A1/zh
Publication of HK1221726B publication Critical patent/HK1221726B/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07KPEPTIDES
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • G01MEASURING; TESTING
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
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    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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HK16109981.4A 2013-09-05 2014-09-05 炎性疾病中的il-18结合蛋白(il-18bp) HK1221726B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13183193 2013-09-05
EP13183193 2013-09-05
PCT/EP2014/069013 WO2015032932A1 (en) 2013-09-05 2014-09-05 Il-18 binding protein (il-18bp) in inflammatory diseases

Publications (2)

Publication Number Publication Date
HK1221726A1 true HK1221726A1 (zh) 2017-06-09
HK1221726B HK1221726B (zh) 2022-03-25

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Also Published As

Publication number Publication date
HUE055608T2 (hu) 2021-12-28
CA2922498A1 (en) 2015-03-12
IL244169B (en) 2019-12-31
CN105722858A (zh) 2016-06-29
PT3041864T (pt) 2021-10-26
US20200392222A1 (en) 2020-12-17
ES2892923T3 (es) 2022-02-07
US11530263B2 (en) 2022-12-20
CN115925928A (zh) 2023-04-07
PL3041864T3 (pl) 2021-12-20
EP3041864A1 (en) 2016-07-13
MX385868B (es) 2025-03-18
JP2016536332A (ja) 2016-11-24
LT3041864T (lt) 2021-10-11
JP2020055821A (ja) 2020-04-09
PH12016500425B1 (en) 2022-07-29
RU2731713C2 (ru) 2020-09-08
NZ717671A (en) 2022-07-01
KR102512797B1 (ko) 2023-03-22
AU2014317035B2 (en) 2020-02-27
EP3978526A1 (en) 2022-04-06
IL244169A0 (en) 2016-04-21
WO2015032932A1 (en) 2015-03-12
CL2016000506A1 (es) 2016-09-23
KR20160044045A (ko) 2016-04-22
SI3041864T1 (sl) 2021-11-30
AU2014317035A2 (en) 2016-04-21
KR102321172B1 (ko) 2021-11-05
US20160215048A1 (en) 2016-07-28
CY1124698T1 (el) 2022-07-22
DK3041864T3 (da) 2021-09-27
RU2016112596A (ru) 2017-10-09
EP3041864B1 (en) 2021-07-21
US20230250164A1 (en) 2023-08-10
UA125204C2 (uk) 2022-02-02
US10858426B2 (en) 2020-12-08
PH12016500425A1 (en) 2016-05-23
JP6820743B2 (ja) 2021-01-27
KR20210132749A (ko) 2021-11-04
BR112016004772A2 (zh) 2017-09-05
AU2014317035A1 (en) 2016-03-10
SG11201601717VA (en) 2016-04-28
MX2016002719A (es) 2016-09-06
RU2016112596A3 (zh) 2018-07-18

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