[go: up one dir, main page]

HK1003111B - 苯并吗啡烷及其作为药物的使用 - Google Patents

苯并吗啡烷及其作为药物的使用 Download PDF

Info

Publication number
HK1003111B
HK1003111B HK98102148.0A HK98102148A HK1003111B HK 1003111 B HK1003111 B HK 1003111B HK 98102148 A HK98102148 A HK 98102148A HK 1003111 B HK1003111 B HK 1003111B
Authority
HK
Hong Kong
Prior art keywords
denotes
group
methyl
alkyl
hydroxy
Prior art date
Application number
HK98102148.0A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1003111A1 (zh
Inventor
Carter Adrian
Grauert Matthias
Merz Herbert
Stransky Werner
Ensinger Helmut
Josef Kuhn Franz
Muller Enzio
Streller Ilse
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4121821A external-priority patent/DE4121821A1/de
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of HK1003111B publication Critical patent/HK1003111B/zh
Publication of HK1003111A1 publication Critical patent/HK1003111A1/zh

Links

HK98102148A 1991-07-02 1998-03-16 苯并嗎啡烷及其作為葯物的使用 HK1003111A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4121821 1991-07-02
DE4121821A DE4121821A1 (de) 1991-07-02 1991-07-02 Neue benzomorphane und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
HK1003111B true HK1003111B (zh) 1998-10-09
HK1003111A1 HK1003111A1 (zh) 1998-10-09

Family

ID=6435223

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98102148A HK1003111A1 (zh) 1991-07-02 1998-03-16 苯并嗎啡烷及其作為葯物的使用

Country Status (24)

Country Link
EP (1) EP0521422B1 (zh)
JP (1) JP3324785B2 (zh)
KR (1) KR100251256B1 (zh)
AT (1) ATE137749T1 (zh)
AU (1) AU657330B2 (zh)
CA (1) CA2072814C (zh)
CZ (1) CZ286949B6 (zh)
DE (2) DE4121821A1 (zh)
DK (1) DK0521422T3 (zh)
ES (1) ES2086585T3 (zh)
FI (1) FI105913B (zh)
GR (1) GR3020124T3 (zh)
HK (1) HK1003111A1 (zh)
HU (1) HU220873B1 (zh)
IE (1) IE74400B1 (zh)
IL (1) IL102361A (zh)
MX (1) MX9203845A (zh)
NO (1) NO178263C (zh)
NZ (1) NZ243388A (zh)
PH (1) PH31430A (zh)
SG (1) SG43001A1 (zh)
SK (1) SK280776B6 (zh)
TW (1) TW214547B (zh)
ZA (1) ZA924883B (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan
DE19740110A1 (de) * 1997-09-12 1999-03-18 Boehringer Ingelheim Pharma Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
JPH1196519A (ja) * 1997-09-17 1999-04-09 Alps Electric Co Ltd スピンバルブ型薄膜素子およびその製造方法
US6136980A (en) * 1998-05-01 2000-10-24 Boehringer Ingelheim Kg Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane
DE19826365A1 (de) * 1998-06-12 1999-12-16 Gruenenthal Gmbh Verwendung von Benzomorphanderivaten als Analgetikum
DE19957156A1 (de) * 1999-11-27 2001-05-31 Boehringer Ingelheim Pharma Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel
US6355652B1 (en) 1999-11-27 2002-03-12 Boehringer Ingelheim Pharma Kg Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as pharmaceutical compositions
DE10204276A1 (de) * 2002-02-02 2003-08-07 Boehringer Ingelheim Pharma N-Allyloxyethyl-1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
AU2003234621A1 (en) 2002-05-17 2003-12-02 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7501433B2 (en) 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
AR069545A1 (es) * 2007-11-16 2010-02-03 Boehringer Ingelheim Pharma Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y
EP3087079B1 (en) 2013-12-26 2019-04-03 Purdue Pharma LP Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7804509A (nl) * 1978-04-26 1979-10-30 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
NL7907800A (nl) * 1979-10-23 1981-04-27 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

Similar Documents

Publication Publication Date Title
DE3527648C2 (zh)
US4451470A (en) Analgesic, antagonist, and/or anorectic 14-fluoromorphinans
US5731318A (en) Benzomorphan derivatives
HK1003111B (zh) 苯并吗啡烷及其作为药物的使用
HK1003111A1 (zh) 苯并嗎啡烷及其作為葯物的使用
OA10200A (fr) Nouveaux dérivés de l'érythromycine leur procédé de préparation et leur application comme médicaments
JPS60358B2 (ja) ベンゾモルフアン化合物の製法
WO1992017473A1 (en) Crystalline tiagabine hydrochloride monohydrate, its preparation and use
DE2305092C2 (zh)
JPH0559049A (ja) N−(アリールオキシアルキル)ヘテロアリール−8−アザビシクロ〔3.2.1〕オクタン、中間体およびそれらの製法
US4087532A (en) Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
US4528289A (en) Corynantheine derivates, processes for their preparation, and their use
EP0052932A1 (en) 2-Aminotetralin compounds and pharmaceutical compositions having central alpha1 agonist activity
JP2002534530A (ja) 細胞癒着阻害剤としての単糖の2,3−o−イソプロピリデン誘導体
EP0002672B1 (de) Substituierte Pyrrolidine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
EP0604352A2 (en) Aryl substituted heterocyclic compounds
PL80112B1 (zh)
EP0003286B1 (de) Ergopeptidalkaloid-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
KR830001838B1 (ko) 페닐-퀴놀리지딘의 제조방법
US4133888A (en) Analgesic and morphine antagonistic 2'-hydroxy-2-(5-isoxazolyl-methyl)-6,7-benzomorphans and salts thereof
CA1041544A (en) Optically active 2,3-cis-1,2,3,4-tetrahydro-5-(2-hydroxy-3-(tertbutylamino)-propoxy)-2,3-naphthalenediols
US20050043396A1 (en) 5-Benzoylamino-1,3-dioxacyclanes, the method for preparing the same and their use as PKC inhibitor
US4038397A (en) Pharmaceutical compositions containing an N-[(methoxymethyl-furyl)-methyl]-6
EP0147774B1 (en) 4,7-dimethyl-2-(4-pyridinyl)-1,2,4-triazolo(1,5-a)pyrimidine-5(4h)-one
JPS61293981A (ja) 12b−置換1−ヒドロキシメチル−オクタヒドロインドロ〔2,3−a〕キノリジン誘導体,それらの製造法及びそれらを含む医薬組成物