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HK10777456A1 - Sustained-release table composition of pramipexole - Google Patents

Sustained-release table composition of pramipexole

Info

Publication number
HK10777456A1
HK10777456A1 HK05109947A HK05109947A HK10777456A1 HK 10777456 A1 HK10777456 A1 HK 10777456A1 HK 05109947 A HK05109947 A HK 05109947A HK 05109947 A HK05109947 A HK 05109947A HK 10777456 A1 HK10777456 A1 HK 10777456A1
Authority
HK
Hong Kong
Prior art keywords
pramipexole
sustained
release table
table composition
release
Prior art date
Application number
HK05109947A
Other languages
English (en)
Other versions
HK1077756A (en
HK1077756B (en
Inventor
Gregory E Amidon
Loksidh D Ganorkar
John M Heimlich
Ernest J Lee
Robert M Noack
Joseph P Reo
Connie J Skoug
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of HK1077756A publication Critical patent/HK1077756A/xx
Publication of HK1077756B publication Critical patent/HK1077756B/xx
Publication of HK10777456A1 publication Critical patent/HK10777456A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
HK05109947A 2002-07-25 2005-11-08 Sustained-release table composition of pramipexole HK10777456A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US39844702P 2002-07-25 2002-07-25
US39842702P 2002-07-25 2002-07-25
US60/398,427 2002-07-25
US60/398,447 2002-07-25
US47951303P 2003-06-18 2003-06-18
US60/479,513 2003-06-18
PCT/US2003/023205 WO2004010997A1 (fr) 2002-07-25 2003-07-25 Composition de comprime a liberation prolongee de pramipexole

Publications (3)

Publication Number Publication Date
HK1077756A HK1077756A (en) 2006-02-24
HK1077756B HK1077756B (en) 2007-11-30
HK10777456A1 true HK10777456A1 (en) 2007-11-30

Family

ID=31192087

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05109947A HK10777456A1 (en) 2002-07-25 2005-11-08 Sustained-release table composition of pramipexole

Country Status (41)

Country Link
US (2) US20050226926A1 (fr)
EP (2) EP1531814B1 (fr)
JP (1) JP4700963B2 (fr)
KR (1) KR100712832B1 (fr)
CN (1) CN1313092C (fr)
AP (1) AP2201A (fr)
AR (1) AR040681A1 (fr)
AT (1) ATE406162T1 (fr)
AU (1) AU2003261241B2 (fr)
BR (1) BR0312960A (fr)
CA (1) CA2492854C (fr)
CR (1) CR7661A (fr)
CU (1) CU23440B7 (fr)
CY (1) CY1110408T1 (fr)
DE (1) DE60323235D1 (fr)
DK (1) DK1531814T3 (fr)
EA (2) EA200702187A1 (fr)
EC (1) ECSP055568A (fr)
ES (1) ES2310673T3 (fr)
GE (1) GEP20074048B (fr)
HK (1) HK10777456A1 (fr)
HR (1) HRP20041235B1 (fr)
IL (1) IL166078A0 (fr)
IS (1) IS7623A (fr)
MA (1) MA27328A1 (fr)
ME (1) MEP52308A (fr)
MX (1) MXPA05001054A (fr)
MY (1) MY138846A (fr)
NO (1) NO334298B1 (fr)
NZ (1) NZ537790A (fr)
OA (1) OA13303A (fr)
PA (1) PA8578301A1 (fr)
PE (1) PE20040130A1 (fr)
PL (1) PL215587B1 (fr)
PT (1) PT1531814E (fr)
RS (1) RS51719B (fr)
SI (1) SI1531814T1 (fr)
TW (1) TWI347849B (fr)
UY (1) UY27912A1 (fr)
WO (1) WO2004010997A1 (fr)
ZA (1) ZA200500439B (fr)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060281797A1 (en) * 2001-12-11 2006-12-14 University Of Virginia Patent Foundation Neurorestoration with R(+) Pramipexole
US7157480B2 (en) * 2001-12-11 2007-01-02 University Of Virginia Patent Foundation Use of pramipexole to treat amyotrophic lateral sclerosis
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
AR040680A1 (es) * 2002-07-25 2005-04-13 Pharmacia Corp Composicion de tabletas de liberacion sostenida
PE20040134A1 (es) * 2002-07-25 2004-03-06 Pharmacia Corp Forma de dosificacion de una vez al dia de pramipexol
JP4959191B2 (ja) 2003-07-11 2012-06-20 旭化成ケミカルズ株式会社 機能性澱粉粉末
NZ553645A (en) 2004-08-13 2010-09-30 Boehringer Ingelheim Int Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
NZ589267A (en) * 2004-08-13 2012-06-29 Boehringer Ingelheim Int Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
PL1803447T3 (pl) * 2004-09-09 2010-05-31 Psicofarma S A De C V Kompozycja farmaceutyczna do długotrwałego uwalniania hydralazyny oraz jej zastosowanie wspomagające w leczeniu raka
EP1731514A1 (fr) * 2005-06-02 2006-12-13 Sandoz AG Méthode de préparation du pramipexole
JP2009504748A (ja) * 2005-08-15 2009-02-05 ユニバーシティ オブ バージニア パテント ファウンデーション R(+)プラミペキソールを用いた神経回復
WO2007090882A2 (fr) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Compositions pharmaceutiques
CA2641665A1 (fr) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Formulation a liberation modifiee
US20090098202A1 (en) * 2006-02-10 2009-04-16 Boehringer Ingelheim International Gmbh Extended Release Formulation
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
US20070259930A1 (en) * 2006-04-10 2007-11-08 Knopp Neurosciences, Inc. Compositions and methods of using r(+) pramipexole
DK2026803T3 (da) * 2006-05-16 2012-04-16 Knopp Neurosciences Inc Sammensætninger af R(+) og S(-) pramipexol og fremgangsmåder til anvendelse heraf
WO2008001204A2 (fr) * 2006-06-29 2008-01-03 Antares Pharma Ipl Ag Compositions transdermiques de pramipexole présentant des propriétés de perméation améliorées
US8524695B2 (en) * 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
AU2008224844B2 (en) * 2007-03-14 2012-08-09 Knopp Neurosciences, Inc. Synthesis of chirally purified substituted benzothiazole diamines
US20100092554A1 (en) * 2007-04-24 2010-04-15 Boehringer Ingelheim International Gmbh Combination with an extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof
US20080299189A1 (en) * 2007-06-04 2008-12-04 Drugtech Corporation Controlled release dopamine agonist compositions
CA2725482A1 (fr) * 2008-06-09 2009-12-17 Supernus Pharmaceuticals, Inc. Formulations a liberation controlee de pramipexole
JP2012500283A (ja) 2008-08-19 2012-01-05 ノップ ニューロサイエンシーズ、インク. (r)−プラミペキソールを使用した組成物並びにその方法
EP2442655A4 (fr) * 2009-06-19 2013-04-03 Knopp Neurosciences Inc Compositions et méthodes pour traiter la sclérose latérale amyotrophique (als)
MX2012000096A (es) * 2009-07-02 2012-04-02 Supernus Pharmaceuticals Inc Un metodo de tratamiento de un trastorno neurologico.
WO2011037976A2 (fr) * 2009-09-22 2011-03-31 Dr. Reddy's Laboratories Limited Formulations pharmaceutiques de pramipexole
WO2011086182A2 (fr) 2010-01-18 2011-07-21 Synthon Bv Comprimés à libération prolongée de pramipexole
TR201001862A1 (tr) 2010-03-11 2011-10-21 Sanovel �La� San.Ve T�C.A.�. Kontrollü salım gerçekleştiren pramipeksol formülasyonları.
WO2011148243A1 (fr) 2010-05-24 2011-12-01 Lupin Limited Formulation à libération prolongée de pramipexole
KR101307334B1 (ko) 2010-07-02 2013-09-12 주식회사 바이오파마티스 프라미펙솔 또는 이의 약학적으로 허용되는 염을 포함하는 안정성이 개선된 서방형 약학 조성물
WO2013034173A1 (fr) 2011-09-06 2013-03-14 Synthon Bv Comprimés à libération prolongée de pramipexole
WO2013096816A1 (fr) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Synthèse améliorée de composés substitués par amine de 4,5,6,7-tétrahydrobenzothiazole
EP2732812A1 (fr) 2012-11-15 2014-05-21 Aristo Pharma GmbH Comprimé de pramipexol à libération prolongée
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
SI3838271T1 (sl) 2013-07-12 2025-12-31 Areteia Therapeutics, Inc. Zdravljenje povišanih ravni eozinofilcev in/ali bazofilcev
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
AU2014306683B2 (en) 2013-08-13 2017-10-12 Knopp Biosciences Llc Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders
PT3033081T (pt) 2013-08-13 2021-06-01 Knopp Biosciences Llc Composições e métodos para o tratamento da urticária crónica
CN103520128B (zh) 2013-10-12 2018-08-21 石家庄杏林锐步医药科技股份有限公司 一种普拉克索的缓释片剂、制备方法及其用途
IL312486B2 (en) 2017-04-10 2025-05-01 Chase Therapeutics Corp NK1 antagonist combination and method for treating synucleinopathies
EA201992532A1 (ru) 2017-04-24 2020-04-03 Чейс Терапьютикс Корпорейшн Композиции и способ для лечения депрессии
KR20200026920A (ko) 2017-06-30 2020-03-11 체이스 테라퓨틱스 코포레이션 우울증을 치료하기 위한 nk-1 길항제 조성물 및 우울증 치료에 사용하는 방법
CN109316466B (zh) * 2017-07-31 2022-04-05 深圳翰宇药业股份有限公司 一种盐酸普拉克索缓释制剂及其制备方法
CN111212640A (zh) 2017-08-17 2020-05-29 顾自强 单胺抗帕金森药物的双羟萘酸盐、其制备方法及其用途
CN113876729B (zh) * 2021-11-11 2023-05-30 南通联亚药业股份有限公司 一种盐酸普拉克索缓释片剂及其制备方法

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US15735A (en) * 1856-09-16 Improvement in harvesters
US2887440A (en) * 1957-08-12 1959-05-19 Dow Chemical Co Enteric coating
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
JPS58403B2 (ja) 1975-07-24 1983-01-06 武田薬品工業株式会社 L− アスコルビンサンセイザイノ セイゾウホウ
US4140755A (en) 1976-02-13 1979-02-20 Hoffmann-La Roche Inc. Sustained release tablet formulations
CH649215A5 (de) 1981-04-29 1985-05-15 Hoffmann La Roche Pharmazeutische praeparate.
SE8103843L (sv) 1981-06-18 1982-12-19 Astra Laekemedel Ab Farmaceutisk mixtur
US4424235A (en) 1981-09-14 1984-01-03 Hoffmann-La Roche Inc. Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor
EP0186087B1 (fr) 1984-12-22 1989-08-23 Dr. Karl Thomae GmbH Tétrahydro-benzothiazoles, leur procédé de préparation et leur utilisation comme intermédiaires ou médicaments
DE3447075A1 (de) * 1984-12-22 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
US4738851A (en) 1985-09-27 1988-04-19 University Of Iowa Research Foundation, Inc. Controlled release ophthalmic gel formulation
US4709712A (en) 1986-10-22 1987-12-01 Dermatalogical Products Of Texas Polycarboxylic acid polymer gels as protective agents
GB8828020D0 (en) 1988-12-01 1989-01-05 Unilever Plc Topical composition
US5026559A (en) 1989-04-03 1991-06-25 Kinaform Technology, Inc. Sustained-release pharmaceutical preparation
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
AU626427B2 (en) 1989-06-09 1992-07-30 Pharmacia & Upjohn Company Heterocyclic amines having central nervous system activity
US5273975A (en) 1989-06-09 1993-12-28 The Upjohn Company Heterocyclic amines having central nervous system activity
GB9015822D0 (en) 1990-07-18 1990-09-05 Beecham Group Plc Compositions
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5656296A (en) * 1992-04-29 1997-08-12 Warner-Lambert Company Dual control sustained release drug delivery systems and methods for preparing same
US5431920A (en) 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
US5458887A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
WO1997004752A1 (fr) * 1995-07-26 1997-02-13 Duramed Pharmaceuticals, Inc. Compositions pharmaceutiques d'oestrogenes conjugues et leurs modes d'emploi
EP0998271B3 (fr) 1997-06-06 2014-10-29 Depomed, Inc. Formes de dosage de medicaments administres par voie orale a retention gastrique pour liberation lente de medicaments hautement solubles
NZ513456A (en) 1997-07-01 2003-02-28 Pfizer Sertraline acetate, L-lactate and L-aspartate, processes for their preparation and their uses in psychotic disorders
US5895663A (en) 1997-07-31 1999-04-20 L. Perrigo Company Pseudoephedrine hydrochloride extended-release tablets
CA2211778A1 (fr) * 1997-08-14 1999-02-14 Francois Carriere Preparation d'un amidon riche en amylose pregelatinise et deramifie utile comme excipient pour la liberation prolongee de principes actifs
US6248358B1 (en) 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US6624200B2 (en) 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
DE69819748T2 (de) 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
US7153845B2 (en) 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6197339B1 (en) * 1997-09-30 2001-03-06 Pharmacia & Upjohn Company Sustained release tablet formulation to treat Parkinson's disease
US6056977A (en) * 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
GB9802201D0 (en) * 1998-02-03 1998-04-01 Cerestar Holding Bv Free-flowable directly compressible starch as binder,disintegrant and filler for compresion tablets and hard gelatine capsules
CA2323177A1 (fr) * 1998-03-11 1999-09-16 Susan Marie Milosovich Composition
GB9812426D0 (en) 1998-06-10 1998-08-05 Reckitt & Colmann Prod Ltd Improvements in or relating to organic compositions
TW407058B (en) * 1998-07-17 2000-10-01 Dev Center Biotechnology Oral cisapride dosage forms with an extended duration
DE19906290A1 (de) 1999-02-15 2000-08-17 Falk Pharma Gmbh Arzneimittel zur Behandlung bzw. Prävention von Darmkrebs
US7374779B2 (en) 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
WO2000059477A1 (fr) 1999-03-31 2000-10-12 Janssen Pharmaceutica N.V. Amidon pregelatinise dans une formulation a liberation regulee
DE19927688A1 (de) * 1999-06-17 2000-12-21 Gruenenthal Gmbh Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
PL196996B1 (pl) 1999-07-01 2008-02-29 Upjohn Co Zastosowanie optycznie czystej (S,S)-reboksetyny lub jej dopuszczalnej farmaceutycznie soli do wytwarzania leku
AP2002002410A0 (en) 1999-08-04 2002-03-31 Ranbaxy Laboratories Ltd Hydrodynamically Balancing Oral Drug Delivery System
CO5210862A1 (es) 1999-09-15 2002-10-30 Alza Corp Formas de dosificacion y metodos para proporcionar efectiva terapia de reboxetina con dosificacion de una vez al dia
CA2384840A1 (fr) 1999-09-30 2001-04-05 The General Hospital Corporation Utilisation de pramipexole pour traiter l'etat de besoin de cocaine
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
PL355391A1 (en) * 1999-12-22 2004-04-19 Pharmacia Corporation Sustained-release formulation of a cyclooxygenase-2 inhibitor
US6467637B2 (en) 2000-01-27 2002-10-22 The York Group, Inc. Death care merchandising system
JP2003523382A (ja) 2000-02-24 2003-08-05 ファルマシア・アンド・アップジョン・カンパニー 新規な薬物の組合せ
US6277875B1 (en) * 2000-07-17 2001-08-21 Andrew J. Holman Use of dopamine D2/D3 receptor agonists to treat fibromyalgia
ES2187249B1 (es) 2000-09-18 2004-09-16 Synthon Bv Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles.
SE0004671D0 (sv) 2000-12-15 2000-12-15 Amarin Dev Ab Pharmaceutical formulation
DE10138275A1 (de) 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
WO2003053402A1 (fr) 2001-12-20 2003-07-03 Pharmacia Corporation Formes dosifiees a liberation soutenue d'ordre zero et procede de production associe
PE20040134A1 (es) 2002-07-25 2004-03-06 Pharmacia Corp Forma de dosificacion de una vez al dia de pramipexol
AR040680A1 (es) 2002-07-25 2005-04-13 Pharmacia Corp Composicion de tabletas de liberacion sostenida
BR0312876A (pt) 2002-07-25 2005-06-28 Pharmacia Corp Método de preparação de formas de dosagem sólidas revestidas em duas camadas compreendendo um polìmero insolúvel em água e um agente formador de poros solúvel em água
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
US20040121010A1 (en) 2002-10-25 2004-06-24 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
AU2003224467A1 (en) 2003-03-11 2004-09-30 Korea United Pharm, Inc. Process for the preparing of hardcapsule formulation containing lansoprazole
WO2004087175A1 (fr) 2003-04-04 2004-10-14 Pharmacia Corporation Tablettes comprimees orales de formulations multiparticulaires a liberation prolongee
US20050020589A1 (en) 2003-06-18 2005-01-27 Pfizer Inc. Sustained-release tablet composition comprising a dopamine receptor agonist
NZ553645A (en) 2004-08-13 2010-09-30 Boehringer Ingelheim Int Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
NZ589267A (en) 2004-08-13 2012-06-29 Boehringer Ingelheim Int Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
WO2006046256A1 (fr) 2004-10-27 2006-05-04 Alembic Limited Formulation a liberation prolongee de dihydrochlorure de pramipexole
EP1901721A1 (fr) 2005-06-23 2008-03-26 Spherics, Inc. Formes de dosage de pramipexole a liberation retardee ou a liberation prolongee/retardee
US20080299204A1 (en) 2005-06-23 2008-12-04 Spherics, Inc. Dosage forms for movement disorder treatment
JP2009504748A (ja) 2005-08-15 2009-02-05 ユニバーシティ オブ バージニア パテント ファウンデーション R(+)プラミペキソールを用いた神経回復
WO2007054976A2 (fr) 2005-11-08 2007-05-18 Panacea Biotec Ltd. Nouvelles compositions pharmaceutiques a liberation controlee a base de lipides
US20090098202A1 (en) 2006-02-10 2009-04-16 Boehringer Ingelheim International Gmbh Extended Release Formulation
CA2641665A1 (fr) 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Formulation a liberation modifiee
WO2007090882A2 (fr) 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Compositions pharmaceutiques
EP1886665A1 (fr) 2006-08-01 2008-02-13 Boehringer Ingelheim Pharma GmbH & Co. KG Système thérapeutique gastro-retentif

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OA13303A (en) 2007-04-13
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CR7661A (es) 2005-06-08
HRP20041235B1 (hr) 2013-07-31
PL215587B1 (pl) 2013-12-31
JP2005538106A (ja) 2005-12-15
AU2003261241A1 (en) 2004-02-16
EP1987832A1 (fr) 2008-11-05
IL166078A0 (en) 2006-01-15
RS20050059A (sr) 2007-08-03
WO2004010997A8 (fr) 2005-02-24
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EA009663B1 (ru) 2008-02-28
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CN1671382A (zh) 2005-09-21
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