DE60323235D1 - Pramipexol-tablette mit verzögerter wirkstoffabgabe - Google Patents
Pramipexol-tablette mit verzögerter wirkstoffabgabeInfo
- Publication number
- DE60323235D1 DE60323235D1 DE60323235T DE60323235T DE60323235D1 DE 60323235 D1 DE60323235 D1 DE 60323235D1 DE 60323235 T DE60323235 T DE 60323235T DE 60323235 T DE60323235 T DE 60323235T DE 60323235 D1 DE60323235 D1 DE 60323235D1
- Authority
- DE
- Germany
- Prior art keywords
- pramipexol
- tablet
- active ingredient
- delayed active
- delayed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39844702P | 2002-07-25 | 2002-07-25 | |
| US39842702P | 2002-07-25 | 2002-07-25 | |
| US47951303P | 2003-06-18 | 2003-06-18 | |
| PCT/US2003/023205 WO2004010997A1 (en) | 2002-07-25 | 2003-07-25 | Sustained-release tablet composition of pramipexole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60323235D1 true DE60323235D1 (de) | 2008-10-09 |
Family
ID=31192087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60323235T Expired - Lifetime DE60323235D1 (de) | 2002-07-25 | 2003-07-25 | Pramipexol-tablette mit verzögerter wirkstoffabgabe |
Country Status (41)
| Country | Link |
|---|---|
| US (2) | US20050226926A1 (de) |
| EP (2) | EP1531814B1 (de) |
| JP (1) | JP4700963B2 (de) |
| KR (1) | KR100712832B1 (de) |
| CN (1) | CN1313092C (de) |
| AP (1) | AP2201A (de) |
| AR (1) | AR040681A1 (de) |
| AT (1) | ATE406162T1 (de) |
| AU (1) | AU2003261241B2 (de) |
| BR (1) | BR0312960A (de) |
| CA (1) | CA2492854C (de) |
| CR (1) | CR7661A (de) |
| CU (1) | CU23440B7 (de) |
| CY (1) | CY1110408T1 (de) |
| DE (1) | DE60323235D1 (de) |
| DK (1) | DK1531814T3 (de) |
| EA (2) | EA009663B1 (de) |
| EC (1) | ECSP055568A (de) |
| ES (1) | ES2310673T3 (de) |
| GE (1) | GEP20074048B (de) |
| HK (1) | HK10777456A1 (de) |
| HR (1) | HRP20041235B1 (de) |
| IL (1) | IL166078A0 (de) |
| IS (1) | IS7623A (de) |
| MA (1) | MA27328A1 (de) |
| ME (1) | MEP52308A (de) |
| MX (1) | MXPA05001054A (de) |
| MY (1) | MY138846A (de) |
| NO (1) | NO334298B1 (de) |
| NZ (1) | NZ537790A (de) |
| OA (1) | OA13303A (de) |
| PA (1) | PA8578301A1 (de) |
| PE (1) | PE20040130A1 (de) |
| PL (1) | PL215587B1 (de) |
| PT (1) | PT1531814E (de) |
| RS (1) | RS51719B (de) |
| SI (1) | SI1531814T1 (de) |
| TW (1) | TWI347849B (de) |
| UY (1) | UY27912A1 (de) |
| WO (1) | WO2004010997A1 (de) |
| ZA (1) | ZA200500439B (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2305252A1 (de) * | 2001-12-11 | 2011-04-06 | University Of Virginia Patent Foundation | Verwendung von Pramipexol zur Behandlung amyotropher Lateralsklerose |
| US20060281797A1 (en) * | 2001-12-11 | 2006-12-14 | University Of Virginia Patent Foundation | Neurorestoration with R(+) Pramipexole |
| US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
| MY136318A (en) * | 2002-07-25 | 2008-09-30 | Pharmacia Corp | Sustained-release tablet composition |
| MY142204A (en) * | 2002-07-25 | 2010-10-29 | Pharmacia Corp | Pramipexole once-daily dosage form |
| CN1823091B (zh) | 2003-07-11 | 2010-05-12 | 旭化成化学株式会社 | 功能性淀粉粉末 |
| KR20070050081A (ko) * | 2004-08-13 | 2007-05-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 프라미펙솔 또는 약제학적으로 허용되는 이의 염을포함하는 연장 방출형 펠렛 제형, 이의 제조방법 및 이의용도 |
| RS52057B2 (sr) * | 2004-08-13 | 2018-03-30 | Boehringer Ingelheim Int | Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so |
| DE602004022205D1 (de) * | 2004-09-09 | 2009-09-03 | Psicofarma S A De C V | Pharmazeutische zusammensetzung für die verzögerte freisetzung von hydralazin und ihre verwendung als unterstützung zur krebstherapie |
| EP1731514A1 (de) * | 2005-06-02 | 2006-12-13 | Sandoz AG | Verfahren zur Herstellung von Pramipexol |
| JP2009504748A (ja) * | 2005-08-15 | 2009-02-05 | ユニバーシティ オブ バージニア パテント ファウンデーション | R(+)プラミペキソールを用いた神経回復 |
| WO2007090882A2 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical extended release compositions comprising pramipexole |
| US20090041844A1 (en) * | 2006-02-10 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Modified Release Formulation |
| WO2007090883A1 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Extended release formulation |
| US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| WO2007121188A2 (en) * | 2006-04-10 | 2007-10-25 | Knopp Neurosciences, Inc. | Compositions and methods of using r(+) pramipexole |
| KR20090021169A (ko) * | 2006-05-16 | 2009-02-27 | 크놉 뉴로사이언시스 인코포레이티드 | R(+) 및 s(-) 프라미펙솔을 포함하는 조성물 및 이의 사용 방법 |
| WO2008001204A2 (en) * | 2006-06-29 | 2008-01-03 | Antares Pharma Ipl Ag | Transdermal compositions of pramipexole having enhanced permeation properties |
| US8524695B2 (en) * | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| JP2010521496A (ja) * | 2007-03-14 | 2010-06-24 | ノップ ニューロサイエンシーズ、インク. | キラル精製置換ベンゾチアゾールジアミンの合成 |
| JP2010525018A (ja) * | 2007-04-24 | 2010-07-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | プラミペキソール又はその医薬的に許容できる塩を含有する徐放性錠剤型製剤との組成物 |
| US20080299189A1 (en) * | 2007-06-04 | 2008-12-04 | Drugtech Corporation | Controlled release dopamine agonist compositions |
| WO2009152041A2 (en) * | 2008-06-09 | 2009-12-17 | Supernus Pharmaceuticals, Inc. | Controlled release formulations of pramipexole |
| US20110190356A1 (en) | 2008-08-19 | 2011-08-04 | Knopp Neurosciences Inc. | Compositions and Methods of Using (R)- Pramipexole |
| WO2010148409A1 (en) * | 2009-06-19 | 2010-12-23 | Knopp Neurosciences, Inc. | Compositions and methods for treating amyotrophic lateral sclerosis |
| EP2448411A4 (de) * | 2009-07-02 | 2012-11-28 | Supernus Pharmaceuticals Inc | Verfahren zur behandlung einer neurologischen störung |
| WO2011037976A2 (en) * | 2009-09-22 | 2011-03-31 | Dr. Reddy's Laboratories Limited | Pramipexole pharmaceutical formulations |
| EP2525786A2 (de) | 2010-01-18 | 2012-11-28 | Synthon BV | Pramipexoltabletten mit verlängerter freisetzung |
| TR201001862A1 (tr) | 2010-03-11 | 2011-10-21 | Sanovel �La� San.Ve T�C.A.�. | Kontrollü salım gerçekleştiren pramipeksol formülasyonları. |
| JP2013526601A (ja) | 2010-05-24 | 2013-06-24 | ルピン・リミテッド | プラミペキソールの徐放性製剤 |
| KR101307334B1 (ko) * | 2010-07-02 | 2013-09-12 | 주식회사 바이오파마티스 | 프라미펙솔 또는 이의 약학적으로 허용되는 염을 포함하는 안정성이 개선된 서방형 약학 조성물 |
| WO2013034173A1 (en) | 2011-09-06 | 2013-03-14 | Synthon Bv | Pramipexole extended release tablets |
| US9512096B2 (en) | 2011-12-22 | 2016-12-06 | Knopp Biosciences, LLP | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| EP2732812A1 (de) | 2012-11-15 | 2014-05-21 | Aristo Pharma GmbH | Pramipexol-Retardtablettenformulierung |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| ES3043076T3 (en) | 2013-07-12 | 2025-11-24 | Areteia Therapeutics Inc | Treating elevated levels of eosinophils and/or basophils |
| EP3038467B1 (de) | 2013-08-13 | 2020-07-29 | Knopp Biosciences LLC | Zusammensetzungen und verfahren zur behandlung von plasmazellenerkrankungen und prolymphozytischen b-zellen-erkrankungen |
| US9763918B2 (en) | 2013-08-13 | 2017-09-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| CN103520128B (zh) | 2013-10-12 | 2018-08-21 | 石家庄杏林锐步医药科技股份有限公司 | 一种普拉克索的缓释片剂、制备方法及其用途 |
| IL312486B2 (en) | 2017-04-10 | 2025-05-01 | Chase Therapeutics Corp | NK1 antagonist combination and method for treating synucleinopathies |
| WO2018200387A1 (en) | 2017-04-24 | 2018-11-01 | Chase Therapeutics Corporation | Compositions and method for treating depression |
| KR20200026920A (ko) | 2017-06-30 | 2020-03-11 | 체이스 테라퓨틱스 코포레이션 | 우울증을 치료하기 위한 nk-1 길항제 조성물 및 우울증 치료에 사용하는 방법 |
| CN109316466B (zh) * | 2017-07-31 | 2022-04-05 | 深圳翰宇药业股份有限公司 | 一种盐酸普拉克索缓释制剂及其制备方法 |
| CA3072994A1 (en) | 2017-08-17 | 2019-02-21 | Zi-Qiang Gu | Pamoate salt of monoamine anti-parkinson's agents, method of preparation and use thereof |
| CN113876729B (zh) * | 2021-11-11 | 2023-05-30 | 南通联亚药业股份有限公司 | 一种盐酸普拉克索缓释片剂及其制备方法 |
Family Cites Families (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US15735A (en) * | 1856-09-16 | Improvement in harvesters | ||
| US2887440A (en) * | 1957-08-12 | 1959-05-19 | Dow Chemical Co | Enteric coating |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| JPS58403B2 (ja) | 1975-07-24 | 1983-01-06 | 武田薬品工業株式会社 | L− アスコルビンサンセイザイノ セイゾウホウ |
| US4140755A (en) | 1976-02-13 | 1979-02-20 | Hoffmann-La Roche Inc. | Sustained release tablet formulations |
| CH649215A5 (de) | 1981-04-29 | 1985-05-15 | Hoffmann La Roche | Pharmazeutische praeparate. |
| SE8103843L (sv) | 1981-06-18 | 1982-12-19 | Astra Laekemedel Ab | Farmaceutisk mixtur |
| US4424235A (en) | 1981-09-14 | 1984-01-03 | Hoffmann-La Roche Inc. | Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor |
| EP0186087B1 (de) | 1984-12-22 | 1989-08-23 | Dr. Karl Thomae GmbH | Tetrahydro-benzthiazole, deren Herstellung und deren Verwendung als Zwischenprodukte oder als Arnzneimittel |
| DE3447075A1 (de) * | 1984-12-22 | 1986-07-03 | Dr. Karl Thomae Gmbh, 7950 Biberach | Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel |
| US4738851A (en) | 1985-09-27 | 1988-04-19 | University Of Iowa Research Foundation, Inc. | Controlled release ophthalmic gel formulation |
| US4709712A (en) | 1986-10-22 | 1987-12-01 | Dermatalogical Products Of Texas | Polycarboxylic acid polymer gels as protective agents |
| GB8828020D0 (en) | 1988-12-01 | 1989-01-05 | Unilever Plc | Topical composition |
| US5026559A (en) | 1989-04-03 | 1991-06-25 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
| US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US5273975A (en) | 1989-06-09 | 1993-12-28 | The Upjohn Company | Heterocyclic amines having central nervous system activity |
| HU210264B (en) | 1989-06-09 | 1995-03-28 | Upjohn Co | Process for producing amines of condensed ring-systems containing nitrogen and pharmaceutical compositions containing them |
| GB9015822D0 (en) | 1990-07-18 | 1990-09-05 | Beecham Group Plc | Compositions |
| US5472712A (en) * | 1991-12-24 | 1995-12-05 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
| US5656296A (en) * | 1992-04-29 | 1997-08-12 | Warner-Lambert Company | Dual control sustained release drug delivery systems and methods for preparing same |
| US5431920A (en) | 1993-09-21 | 1995-07-11 | Merck Frosst, Canada, Inc. | Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents |
| US5458887A (en) * | 1994-03-02 | 1995-10-17 | Andrx Pharmaceuticals, Inc. | Controlled release tablet formulation |
| WO1997004752A1 (en) * | 1995-07-26 | 1997-02-13 | Duramed Pharmaceuticals, Inc. | Pharmaceutical compositions of conjugated estrogens and methods for their use |
| WO1998055107A1 (en) | 1997-06-06 | 1998-12-10 | Depomed, Inc. | Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs |
| NZ513456A (en) * | 1997-07-01 | 2003-02-28 | Pfizer | Sertraline acetate, L-lactate and L-aspartate, processes for their preparation and their uses in psychotic disorders |
| US5895663A (en) | 1997-07-31 | 1999-04-20 | L. Perrigo Company | Pseudoephedrine hydrochloride extended-release tablets |
| CA2211778A1 (en) * | 1997-08-14 | 1999-02-14 | Francois Carriere | Preparation of pregelatinized high amylose starch and debranched starch useful as an excipient for controlled release of active agents |
| US7153845B2 (en) | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US6248358B1 (en) | 1998-08-25 | 2001-06-19 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets and methods of making and using the same |
| DE69819748T2 (de) | 1997-09-12 | 2004-09-30 | Columbia Laboratories (Bermuda) Ltd. | Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen |
| US6624200B2 (en) | 1998-08-25 | 2003-09-23 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US6197339B1 (en) * | 1997-09-30 | 2001-03-06 | Pharmacia & Upjohn Company | Sustained release tablet formulation to treat Parkinson's disease |
| US6056977A (en) * | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
| GB9802201D0 (en) * | 1998-02-03 | 1998-04-01 | Cerestar Holding Bv | Free-flowable directly compressible starch as binder,disintegrant and filler for compresion tablets and hard gelatine capsules |
| KR20010034588A (ko) * | 1998-03-11 | 2001-04-25 | 피터 기딩스 | 조성물 |
| GB9812426D0 (en) | 1998-06-10 | 1998-08-05 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| TW407058B (en) * | 1998-07-17 | 2000-10-01 | Dev Center Biotechnology | Oral cisapride dosage forms with an extended duration |
| DE19906290A1 (de) | 1999-02-15 | 2000-08-17 | Falk Pharma Gmbh | Arzneimittel zur Behandlung bzw. Prävention von Darmkrebs |
| US7374779B2 (en) | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| EE05022B1 (et) * | 1999-03-31 | 2008-06-16 | Janssen Pharmaceutica N.V. | Eelthelatineeritud tärklise kasutamine hüdrofiilses kontrollitud vabanemisega preparaadis ja hüdrofiilne kontrollitud vabanemisega preparaat |
| DE19927688A1 (de) | 1999-06-17 | 2000-12-21 | Gruenenthal Gmbh | Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
| EP2090312A1 (de) | 1999-07-01 | 2009-08-19 | Pharmacia & Upjohn Company LLC | (S,S) Reboxetine zur Behandlung von Aufmerksamkeitsstörungen |
| AU5060499A (en) | 1999-08-04 | 2001-03-05 | Ranbaxy Laboratories Limited | Hydrodynamically balanced oral drug delivery system |
| US6387403B1 (en) | 1999-09-15 | 2002-05-14 | Alza Corporation | Dosage forms and methods for providing effective reboxetine therapy with once-a-day dosing |
| AU7620600A (en) | 1999-09-30 | 2001-04-30 | General Hospital Corporation, The | Use of pramipexole as a treatment for cocaine craving |
| US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| CA2394222A1 (en) * | 1999-12-22 | 2001-06-28 | Pharmacia Corporation | Sustained-release formulation of a cyclooxygenase-2 inhibitor |
| US6467637B2 (en) | 2000-01-27 | 2002-10-22 | The York Group, Inc. | Death care merchandising system |
| NZ520975A (en) | 2000-02-24 | 2004-03-26 | Upjohn Co | New drug combinations containing a norepinephrine reuptake inhibitor and an antimuscarinic agent for treating nervous system disorders |
| US6277875B1 (en) * | 2000-07-17 | 2001-08-21 | Andrew J. Holman | Use of dopamine D2/D3 receptor agonists to treat fibromyalgia |
| ES2187249B1 (es) | 2000-09-18 | 2004-09-16 | Synthon Bv | Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles. |
| SE0004671D0 (sv) | 2000-12-15 | 2000-12-15 | Amarin Dev Ab | Pharmaceutical formulation |
| DE10138275A1 (de) | 2001-08-10 | 2003-02-27 | Boehringer Ingelheim Pharma | Verbindungen zur Beseitigung der Anhedonie |
| BR0215262A (pt) | 2001-12-20 | 2004-12-28 | Pharmacia Corp | Formas de dosagem com liberação sustentada de ordem zero e processo para a fabricação das mesmas |
| US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
| JP2005538105A (ja) | 2002-07-25 | 2005-12-15 | ファルマシア・コーポレーション | 水不溶性ポリマーおよび水溶性の小孔形成物質からなる2層により被覆された固体剤形の製造方法 |
| MY136318A (en) * | 2002-07-25 | 2008-09-30 | Pharmacia Corp | Sustained-release tablet composition |
| MY142204A (en) | 2002-07-25 | 2010-10-29 | Pharmacia Corp | Pramipexole once-daily dosage form |
| US20040121010A1 (en) | 2002-10-25 | 2004-06-24 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| AU2003224467A1 (en) | 2003-03-11 | 2004-09-30 | Korea United Pharm, Inc. | Process for the preparing of hardcapsule formulation containing lansoprazole |
| CA2520321A1 (en) | 2003-04-04 | 2004-10-14 | Pharmacia Corporation | Oral extended release compressed tablets of multiparticulates |
| US20050020589A1 (en) | 2003-06-18 | 2005-01-27 | Pfizer Inc. | Sustained-release tablet composition comprising a dopamine receptor agonist |
| KR20070050081A (ko) | 2004-08-13 | 2007-05-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 프라미펙솔 또는 약제학적으로 허용되는 이의 염을포함하는 연장 방출형 펠렛 제형, 이의 제조방법 및 이의용도 |
| RS52057B2 (sr) | 2004-08-13 | 2018-03-30 | Boehringer Ingelheim Int | Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so |
| WO2006046256A1 (en) | 2004-10-27 | 2006-05-04 | Alembic Limited | Extended release formulation of pramipexole dihydrochloride |
| EP1901720A2 (de) | 2005-06-23 | 2008-03-26 | Spherics, Inc. | Verbesserte dosierformen zur behandlung von bewegungsstörungen |
| EP1901721A1 (de) | 2005-06-23 | 2008-03-26 | Spherics, Inc. | Dosierformen von pramipexol mit verzögerter oder verlängerter-verzögerter freisetzung |
| JP2009504748A (ja) | 2005-08-15 | 2009-02-05 | ユニバーシティ オブ バージニア パテント ファウンデーション | R(+)プラミペキソールを用いた神経回復 |
| WO2007054976A2 (en) | 2005-11-08 | 2007-05-18 | Panacea Biotec Ltd. | Lipid based controlled release pharmaceutical composition |
| WO2007090883A1 (en) | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Extended release formulation |
| WO2007090882A2 (en) | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical extended release compositions comprising pramipexole |
| US20090041844A1 (en) | 2006-02-10 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Modified Release Formulation |
| EP1886665A1 (de) | 2006-08-01 | 2008-02-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Gastroretentives Freisetzungssystem |
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Owner name: BOEHRINGER INGELHEIM INTERNATIONAL GMBH, 55218, DE |