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HK1064370A1 - 作为pdf抑制剂的n-甲酸羟胺化合物 - Google Patents

作为pdf抑制剂的n-甲酸羟胺化合物 Download PDF

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Publication number
HK1064370A1
HK1064370A1 HK04107013A HK04107013A HK1064370A1 HK 1064370 A1 HK1064370 A1 HK 1064370A1 HK 04107013 A HK04107013 A HK 04107013A HK 04107013 A HK04107013 A HK 04107013A HK 1064370 A1 HK1064370 A1 HK 1064370A1
Authority
HK
Hong Kong
Prior art keywords
pyrrolidine
carboxylic acid
methyl
pyridin
amide
Prior art date
Application number
HK04107013A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1064370B (zh
Inventor
Dinesh V. Patel
Zhengyu Yuan
Rakesh K. Jain
Salvador Garcia Alvarez
Jeffrey Jacobs
Original Assignee
Vicuron Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vicuron Pharmaceuticals, Inc. filed Critical Vicuron Pharmaceuticals, Inc.
Publication of HK1064370A1 publication Critical patent/HK1064370A1/zh
Publication of HK1064370B publication Critical patent/HK1064370B/zh

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK04107013.4A 2001-06-15 2002-06-14 作為pdf抑制劑的n-甲酸羥胺化合物 HK1064370B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US29841901P 2001-06-15 2001-06-15
US60/298,419 2001-06-15
US36031302P 2002-02-27 2002-02-27
US60/360,313 2002-02-27
PCT/EP2002/006604 WO2002102790A1 (en) 2001-06-15 2002-06-14 N-formyl hydroxylamine compounds as inhibitors of pdf

Publications (2)

Publication Number Publication Date
HK1064370A1 true HK1064370A1 (zh) 2005-01-28
HK1064370B HK1064370B (zh) 2006-10-20

Family

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Also Published As

Publication number Publication date
AR036053A1 (es) 2004-08-04
KR20060014083A (ko) 2006-02-14
HUP0400208A3 (en) 2008-10-28
EP1401828B1 (en) 2006-04-12
WO2002102790A1 (en) 2002-12-27
EP1401828A1 (en) 2004-03-31
RU2325386C2 (ru) 2008-05-27
AU2002321062B2 (en) 2006-02-02
HUP0400208A2 (hu) 2004-06-28
IL158770A0 (en) 2004-05-12
JP4361365B2 (ja) 2009-11-11
CO5640131A2 (es) 2006-05-31
PE20030100A1 (es) 2003-03-28
CN1511152A (zh) 2004-07-07
KR100589544B1 (ko) 2006-06-15
MY138619A (en) 2009-07-31
DK1401828T3 (da) 2006-07-31
SK15242003A3 (sk) 2004-07-07
CZ20033388A3 (en) 2004-03-17
ZA200308379B (en) 2004-05-21
ES2262824T3 (es) 2006-12-01
BR0210377A (pt) 2004-08-10
CY1105085T1 (el) 2009-11-04
RU2003137565A (ru) 2005-05-27
DE60210612D1 (de) 2006-05-24
NO20035571D0 (no) 2003-12-12
NZ529489A (en) 2005-10-28
NO327420B1 (no) 2009-06-29
CA2448526A1 (en) 2002-12-27
SI1401828T1 (sl) 2006-10-31
US7148242B2 (en) 2006-12-12
MXPA03011628A (es) 2005-03-07
ATE323081T1 (de) 2006-04-15
NO20035571L (no) 2004-02-16
US20030045479A1 (en) 2003-03-06
DE60210612T2 (de) 2006-09-21
KR20040010721A (ko) 2004-01-31
PL364476A1 (en) 2004-12-13
JP2005502606A (ja) 2005-01-27
PT1401828E (pt) 2006-08-31

Similar Documents

Publication Publication Date Title
EP1401828B1 (en) N-formyl hydroxylamine compounds as inhibitors of pdf
AU2002321062A1 (en) N-formyl hydroxylamine compounds as inhibitors of PDF
US20090149509A1 (en) Novel pyrrolidine bicyclic compounds and its derivatives, compositions and methods of use
AU2007226715A1 (en) N-formyl hydroxylamine compounds
EP1896452B1 (en) N-formyl hydroxylamine compounds
HK1064370B (zh) 作為pdf抑制劑的n-甲酸羥胺化合物
CN101654451A (zh) 作为pdf抑制剂的n-甲酰基羟胺类化合物

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100614