HK1042036A1 - 钙溶解化合物 - Google Patents

钙溶解化合物 Download PDF

Info

Publication number: HK1042036A1
Authority: HK; Hong Kong
Prior art keywords: calcilytic compounds; compounds; calcilytic; novel calcilytic; novel
Prior art date: 1999-02-02

Application number

HK02101521.4A

Other languages

English (en)

Inventor

M. Lago Amparo

Original Assignee

Smithkline Beecham Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-02

Filing date

2000-02-02

Publication date

2002-08-02

2000-02-02 Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation

2002-08-02 Publication of HK1042036A1 publication Critical patent/HK1042036A1/zh

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/57—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Obesity (AREA)
Biomedical Technology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Hydrogenated Pyridines (AREA)

HK02101521.4A 1999-02-02 2000-02-02 钙溶解化合物 HK1042036A1 (zh)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11824099P	1999-02-02	1999-02-02
US60/118,240		1999-02-02
PCT/US2000/002676 WO2000045816A1 (en)	1999-02-02	2000-02-02	Calcilytic compounds

Publications (1)

Publication Number	Publication Date
HK1042036A1 true HK1042036A1 (zh)	2002-08-02

Family

ID=22377367

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK02101521.4A HK1042036A1 (zh)	1999-02-02	2000-02-02	钙溶解化合物

Country Status (24)

Country	Link
US (1)	US6417215B1 (zh)
EP (1)	EP1148876A4 (zh)
JP (1)	JP2002536330A (zh)
KR (1)	KR20010093285A (zh)
CN (1)	CN1346269A (zh)
AP (1)	AP2001002220A0 (zh)
AU (1)	AU3480200A (zh)
BG (1)	BG105847A (zh)
BR (1)	BR0007922A (zh)
CA (1)	CA2361589A1 (zh)
CO (1)	CO5251439A1 (zh)
CZ (1)	CZ20012797A3 (zh)
EA (1)	EA200100854A1 (zh)
HK (1)	HK1042036A1 (zh)
HU (1)	HUP0200121A3 (zh)
ID (1)	ID29533A (zh)
IL (1)	IL144470A0 (zh)
MA (1)	MA25379A1 (zh)
NO (1)	NO20013769L (zh)
OA (1)	OA11757A (zh)
PE (1)	PE20001456A1 (zh)
SK (1)	SK10982001A3 (zh)
WO (1)	WO2000045816A1 (zh)
ZA (1)	ZA200106298B (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6916956B2 (en)	2000-08-11	2005-07-12	Japan Tobacco, Inc.	Calcium receptor antagonist
AU2002230579A1 (en) *	2000-10-25	2002-05-06	Smithkline Beecham Corp	Calcilytic compounds
US6864267B2 (en) *	2001-07-16	2005-03-08	Smithkline Beecham Corporation	Calcilytic compounds
MY143244A (en)	2002-11-26	2011-04-15	Smithkline Beecham Corp	Calcilytic compounds
US7105537B2 (en)	2003-01-28	2006-09-12	Bristol-Myers Squibb Company	2-substituted cyclic amines as calcium sensing receptor modulators
US7205322B2 (en)	2003-02-12	2007-04-17	Bristol-Myers Squibb Company	Thiazolidine compounds as calcium sensing receptor modulators
CA2513738C (en) *	2003-04-23	2010-04-06	Japan Tobacco Inc.	Casr antagonist
US7265145B2 (en)	2003-05-28	2007-09-04	Bristol-Myers Squibb Company	Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method
JPWO2004106280A1 (ja)	2003-05-28	2006-07-20	日本たばこ産業株式会社	ＣａＳＲアンタゴニスト
EP1964548A1 (en) *	2007-03-02	2008-09-03	Novartis AG	Pharmaceutical compositions comprising a calcilytic agent
US8039514B2 (en)	2008-06-05	2011-10-18	Asahi Kasei Pharma Corporation	Sulfonamide compounds and use thereof
WO2010103429A1 (en)	2009-03-10	2010-09-16	Pfizer Inc.	1,1-(Dimethyl-Ethylamino)-2-Hydroxy-Propoxy]-Ethyl}-3-Methyl-Biphenyl-4- Carboxylic Acid Derivatives As Calcium Receptor Antagonists
GB201217330D0 (en)	2012-09-28	2012-11-14	Univ Cardiff	Therapeutic for treating inflammatory lung disorders
WO2021029517A1 (en) *	2019-08-13	2021-02-18	Dongguk University Industry-Academic Cooperation Foundation	Pharmaceutical composition for improving or treating post-surgical hypoparathyroidism and treatment method using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE122010000024I1 (de) *	1990-02-19	2010-07-08	Novartis Ag	Acylverbindungen
DE4102024A1 (de) *	1991-01-24	1992-07-30	Thomae Gmbh Dr K	Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
BR9708632A (pt) *	1996-04-09	2000-01-18	Nps Pharma Inc	Composto calcilìticos
UY24949A1 (es) *	1997-04-08	2001-04-30	Smithkline Beecham Corp	Compuestos calcilíticos

2000
- 2000-02-01 PE PE2000000070A patent/PE20001456A1/es not_active Application Discontinuation
- 2000-02-02 KR KR1020017009467A patent/KR20010093285A/ko not_active Withdrawn
- 2000-02-02 CN CN00805996A patent/CN1346269A/zh active Pending
- 2000-02-02 EP EP00913335A patent/EP1148876A4/en not_active Withdrawn
- 2000-02-02 CO CO00006199A patent/CO5251439A1/es unknown
- 2000-02-02 SK SK1098-2001A patent/SK10982001A3/sk unknown
- 2000-02-02 WO PCT/US2000/002676 patent/WO2000045816A1/en not_active Ceased
- 2000-02-02 OA OA1200100199A patent/OA11757A/en unknown
- 2000-02-02 US US09/890,310 patent/US6417215B1/en not_active Expired - Lifetime
- 2000-02-02 AU AU34802/00A patent/AU3480200A/en not_active Abandoned
- 2000-02-02 AP APAP/P/2001/002220A patent/AP2001002220A0/en unknown
- 2000-02-02 BR BR0007922-7A patent/BR0007922A/pt not_active IP Right Cessation
- 2000-02-02 CA CA002361589A patent/CA2361589A1/en not_active Abandoned
- 2000-02-02 ID IDW00200101673A patent/ID29533A/id unknown
- 2000-02-02 EA EA200100854A patent/EA200100854A1/ru unknown
- 2000-02-02 IL IL14447000A patent/IL144470A0/xx unknown
- 2000-02-02 CZ CZ20012797A patent/CZ20012797A3/cs unknown
- 2000-02-02 HU HU0200121A patent/HUP0200121A3/hu unknown
- 2000-02-02 HK HK02101521.4A patent/HK1042036A1/zh unknown
- 2000-02-02 JP JP2000596936A patent/JP2002536330A/ja not_active Withdrawn
2001
- 2001-07-31 ZA ZA200106298A patent/ZA200106298B/en unknown
- 2001-08-01 MA MA26283A patent/MA25379A1/fr unknown
- 2001-08-01 NO NO20013769A patent/NO20013769L/no not_active Application Discontinuation
- 2001-08-27 BG BG105847A patent/BG105847A/xx unknown

Also Published As

Publication number	Publication date
ZA200106298B (en)	2002-10-18
AP2001002220A0 (en)	2001-09-30
OA11757A (en)	2005-07-19
NO20013769D0 (no)	2001-08-01
ID29533A (id)	2001-09-06
WO2000045816A1 (en)	2000-08-10
AU3480200A (en)	2000-08-25
CN1346269A (zh)	2002-04-24
CO5251439A1 (es)	2003-02-28
SK10982001A3 (sk)	2001-12-03
EA200100854A1 (ru)	2002-02-28
PE20001456A1 (es)	2001-01-28
HUP0200121A2 (hu)	2002-05-29
MA25379A1 (fr)	2002-04-01
HUP0200121A3 (en)	2002-11-28
IL144470A0 (en)	2002-05-23
CA2361589A1 (en)	2000-08-10
CZ20012797A3 (cs)	2002-01-16
US6417215B1 (en)	2002-07-09
JP2002536330A (ja)	2002-10-29
BR0007922A (pt)	2001-11-06
EP1148876A4 (en)	2003-07-23
NO20013769L (no)	2001-09-26
BG105847A (en)	2002-04-30
EP1148876A1 (en)	2001-10-31
KR20010093285A (ko)	2001-10-27

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