GT200600427A - Compuestos organicos - Google Patents
Compuestos organicosInfo
- Publication number
- GT200600427A GT200600427A GT200600427A GT200600427A GT200600427A GT 200600427 A GT200600427 A GT 200600427A GT 200600427 A GT200600427 A GT 200600427A GT 200600427 A GT200600427 A GT 200600427A GT 200600427 A GT200600427 A GT 200600427A
- Authority
- GT
- Guatemala
- Prior art keywords
- manufacture
- invention refers
- organic compounds
- same
- formula
- Prior art date
Links
- 150000002894 organic compounds Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
Abstract
LA INVENCIÓN SE REFIERE A UN PROCESO NOVEDOSO, A PASOS DE PROCESO NOVEDOSOS, Y A INTERMEDIARIOS NOVEDOSOS ÚTILES EN LA SÍNTESIS DE COMPUESTOS FARMACÉUTICAMENTE ACTIVOS, EN ESPECIAL INHIBIDORES DE RENINA, TALES COMO ALISQUIRENO. ENTRE OTRAS COSAS, LA INVENCIÓN SE REFIERE A UN PROCESO PARA LA FABRICACIÓN DE UN COMPUESTO DE FÓRMULA III, EN DONDE R, R1 Y R´SON COMO SE DEFINEN EN LA MEMORIA DESCRIPTIVA, O UNA SAL DEL MISMO, Y UN COMPUESTO DE LA FÓRMULA IV, EN DONDE R, R1, R2 Y R´ SON COMO SE DEFINEN EN LA MEMORIA DESCRIPTIVA, Y A PROCESOS PARA LA FABRICACIÓN DE LOS MISMOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0519764.5A GB0519764D0 (en) | 2005-09-28 | 2005-09-28 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT200600427A true GT200600427A (es) | 2007-04-30 |
Family
ID=35394904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT200600427A GT200600427A (es) | 2005-09-28 | 2006-09-25 | Compuestos organicos |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US7973175B2 (es) |
| EP (2) | EP2287153A1 (es) |
| JP (1) | JP2009509990A (es) |
| KR (1) | KR20080048042A (es) |
| CN (1) | CN101273012A (es) |
| AR (1) | AR057137A1 (es) |
| AT (1) | ATE492533T1 (es) |
| AU (1) | AU2006299097B2 (es) |
| BR (1) | BRPI0616707A2 (es) |
| CA (1) | CA2623495A1 (es) |
| DE (1) | DE602006019114D1 (es) |
| EC (1) | ECSP088319A (es) |
| ES (1) | ES2358536T3 (es) |
| GB (1) | GB0519764D0 (es) |
| GT (1) | GT200600427A (es) |
| IL (1) | IL189763A0 (es) |
| MA (1) | MA29852B1 (es) |
| MY (1) | MY143251A (es) |
| NO (1) | NO20082005L (es) |
| NZ (1) | NZ566429A (es) |
| PE (1) | PE20070488A1 (es) |
| PL (1) | PL1931629T3 (es) |
| PT (1) | PT1931629E (es) |
| RU (1) | RU2423348C2 (es) |
| TN (1) | TNSN08142A1 (es) |
| TW (1) | TW200730480A (es) |
| WO (1) | WO2007039183A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2062874B1 (en) | 2007-11-20 | 2014-12-17 | KRKA, tovarna zdravil, d.d., Novo mesto | Process and intermediates for the preparation of aliskiren |
| EP2189442B1 (en) | 2008-11-20 | 2014-10-01 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process and intermediates for the preparation of aliskiren |
| US8203005B2 (en) | 2009-10-29 | 2012-06-19 | Carbo Design Llc | Manufacturing process for enantiomerically pure 8-aryloctanoic acids as Aliskiren |
| CN101774986B (zh) * | 2010-01-06 | 2012-03-28 | 浙江天宇药业股份有限公司 | 一种制备阿利克伦及其中间体的方法 |
| CN101863796B (zh) * | 2010-05-12 | 2011-08-24 | 海南美兰史克制药有限公司 | 一种阿利克仑化合物及其制法 |
| EP2551260A1 (en) | 2011-07-28 | 2013-01-30 | Chemo Ibérica, S.A. | Chemical process for opening ring compounds |
| US8703976B2 (en) | 2011-10-02 | 2014-04-22 | Milan Soukup | Manufacturing process for 8-aryloctanoic acids such as Aliskiren |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3421295A1 (de) | 1984-06-08 | 1985-12-12 | Basf Ag, 6700 Ludwigshafen | Neue pyrrolidincarbonsaeurederivative, verfahren zu ihrer herstellung |
| MY119161A (en) | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
| HU228526B1 (hu) | 2000-07-05 | 2013-03-28 | Speedel Pharma Ag | Eljárás szubsztituált oktanoil-amid-származékok elõállítására, valamint az elõállításhoz alkalmazott közbensõ termékek |
| DE10116816A1 (de) | 2001-04-04 | 2002-10-17 | Basf Ag | Verfahren zur Herstellung von N-Benzylaminen |
| GB0419361D0 (en) | 2004-08-31 | 2004-10-06 | Novartis Ag | Organic compounds |
-
2005
- 2005-09-28 GB GBGB0519764.5A patent/GB0519764D0/en not_active Ceased
-
2006
- 2006-09-25 GT GT200600427A patent/GT200600427A/es unknown
- 2006-09-26 JP JP2008532650A patent/JP2009509990A/ja active Pending
- 2006-09-26 DE DE602006019114T patent/DE602006019114D1/de active Active
- 2006-09-26 PT PT06805861T patent/PT1931629E/pt unknown
- 2006-09-26 AR ARP060104197A patent/AR057137A1/es not_active Application Discontinuation
- 2006-09-26 US US12/067,055 patent/US7973175B2/en not_active Expired - Fee Related
- 2006-09-26 EP EP10178025A patent/EP2287153A1/en not_active Withdrawn
- 2006-09-26 CN CNA2006800353469A patent/CN101273012A/zh active Pending
- 2006-09-26 PE PE2006001166A patent/PE20070488A1/es not_active Application Discontinuation
- 2006-09-26 KR KR1020087007396A patent/KR20080048042A/ko not_active Ceased
- 2006-09-26 WO PCT/EP2006/009323 patent/WO2007039183A1/en not_active Ceased
- 2006-09-26 MY MYPI20080623A patent/MY143251A/en unknown
- 2006-09-26 RU RU2008116317/04A patent/RU2423348C2/ru not_active IP Right Cessation
- 2006-09-26 ES ES06805861T patent/ES2358536T3/es active Active
- 2006-09-26 BR BRPI0616707-1A patent/BRPI0616707A2/pt not_active IP Right Cessation
- 2006-09-26 AT AT06805861T patent/ATE492533T1/de active
- 2006-09-26 EP EP06805861A patent/EP1931629B1/en not_active Not-in-force
- 2006-09-26 PL PL06805861T patent/PL1931629T3/pl unknown
- 2006-09-26 AU AU2006299097A patent/AU2006299097B2/en not_active Ceased
- 2006-09-26 NZ NZ566429A patent/NZ566429A/en not_active IP Right Cessation
- 2006-09-26 CA CA002623495A patent/CA2623495A1/en not_active Abandoned
- 2006-09-27 TW TW095135800A patent/TW200730480A/zh unknown
-
2008
- 2008-02-25 IL IL189763A patent/IL189763A0/en unknown
- 2008-03-27 TN TNP2008000142A patent/TNSN08142A1/en unknown
- 2008-03-27 EC EC2008008319A patent/ECSP088319A/es unknown
- 2008-04-04 MA MA30815A patent/MA29852B1/fr unknown
- 2008-04-28 NO NO20082005A patent/NO20082005L/no not_active Application Discontinuation
-
2011
- 2011-05-26 US US13/116,349 patent/US20110230665A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006299097A1 (en) | 2007-04-12 |
| ECSP088319A (es) | 2008-04-28 |
| JP2009509990A (ja) | 2009-03-12 |
| ES2358536T3 (es) | 2011-05-11 |
| AR057137A1 (es) | 2007-11-21 |
| MY143251A (en) | 2011-04-15 |
| RU2008116317A (ru) | 2009-11-10 |
| EP1931629B1 (en) | 2010-12-22 |
| GB0519764D0 (en) | 2005-11-09 |
| PE20070488A1 (es) | 2007-06-13 |
| NO20082005L (no) | 2008-06-24 |
| MA29852B1 (fr) | 2008-10-03 |
| BRPI0616707A2 (pt) | 2011-06-28 |
| CN101273012A (zh) | 2008-09-24 |
| US20110230665A1 (en) | 2011-09-22 |
| WO2007039183A1 (en) | 2007-04-12 |
| AU2006299097B2 (en) | 2010-11-04 |
| US7973175B2 (en) | 2011-07-05 |
| NZ566429A (en) | 2010-10-29 |
| EP2287153A1 (en) | 2011-02-23 |
| US20080255369A1 (en) | 2008-10-16 |
| PL1931629T3 (pl) | 2011-05-31 |
| DE602006019114D1 (de) | 2011-02-03 |
| CA2623495A1 (en) | 2007-04-12 |
| IL189763A0 (en) | 2008-08-07 |
| TW200730480A (en) | 2007-08-16 |
| PT1931629E (pt) | 2011-03-09 |
| TNSN08142A1 (en) | 2009-07-14 |
| RU2423348C2 (ru) | 2011-07-10 |
| ATE492533T1 (de) | 2011-01-15 |
| KR20080048042A (ko) | 2008-05-30 |
| EP1931629A1 (en) | 2008-06-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ECSP099708A (es) | Nuevos métodos | |
| ECSP088368A (es) | Derivados de 3-alquil-5-(4-alquil-5-oxo-tetrahidrofuran-2-il)-pirrolidin-2-ona como intermediarios en la síntesis de inhibidores de renina | |
| CU20090225A7 (es) | 2-piperidinilo bencimidazoles útiles en el tratamiento del crecimiento celular anormal | |
| CU20190086A7 (es) | Compuestos de heteroarilo bicíclicos 6-6 fusionados útiles como inhibidores de lats | |
| GT200700036A (es) | Compuestos fenil amido heterociclicos condensados | |
| CO6700837A2 (es) | Proceso de elaboración para derivados de prrimidina | |
| UY32096A (es) | Derivados de 2-carboxamida - cicloamino - urea especìficos, sus sales farmacèuticamente aceptables, composiciones contenièndolos, pro-farmacos de los mismos, procesos para su produciòn y aplicaciones | |
| ECSP12011799A (es) | Compuestos de espiropiperidina y uso farmacéutico de los mismos | |
| CL2009000394A1 (es) | Compuestos derivados de n-(1h-indazol-5-il)pirrolidin-3-carboxamida sustituida, inhibidores de erk; composicion farmaceutica; y su uso en el tratamiento del cancer. | |
| CR20140361A (es) | Inhibidores de pde9 con estructura básica de imidazotriazinona | |
| CO6220955A2 (es) | Una composicion farmaceutica que contiene (a) n1-(5-cloropiridin-2-il)-n2-((1s,2r,4s)-4-[dimetilamino)carbonil]-2-{[(5-metil-4,5,6,7-tetrahidrotiazol[5,4-c]piridin-2-il) carbonil] amino} coclohexil)etanodiamida | |
| DOP2011000113A (es) | Pirazolilaminopiridinas como inhibidores de fak | |
| DOP2006000170A (es) | Nuevos derivados de espirocromanona | |
| CR20120296A (es) | Nuevos compuestos de espiropiperidina | |
| AR066709A1 (es) | Proceso para la produccion de pirazoles | |
| CU20150084A7 (es) | Derivados del ácido 4-((1,1) bisfenil -4-il)-3-(3-fosfonopropanamido)butanoico,activo como inhibidores de nep(endopeptidasa neutral) | |
| ECSP088319A (es) | Síntesis de inhibidores de renina que involucra una reacción de cicloadición | |
| GT200900009A (es) | Bencilaminas, un proceso para su produccion y su uso como agentes anti-inflamatorios | |
| CU20110101A7 (es) | 1-(arilsulfonil)-4-(piperazin-1-il)-1h-benzimidazoles como ligandos de 5-hidroxitriptamina-6 | |
| PE20151055A1 (es) | Compuestos triciclicos para inhibir el canal cftr | |
| ECSP077986A (es) | Procedimiento para preparar inhibidores de renina | |
| ECSP088781A (es) | Derivados de benzimidazol | |
| PE20070122A1 (es) | Proceso para preparar derivados de piperazina azindoloxoacetica sustituida con triazol y nuevas formas de sal producidas de los mismos | |
| EA201000616A1 (ru) | Фунгицидные соединения, способ их получения и их применение для борьбы с вредными грибами, а также содержащие их средства | |
| NO20080262L (no) | Fremgangsmate for produksjonen av intermediater for fremstilling av tricykliske benzimidazoler |