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GT200300046A - Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso - Google Patents

Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso

Info

Publication number
GT200300046A
GT200300046A GT200300046A GT200300046A GT200300046A GT 200300046 A GT200300046 A GT 200300046A GT 200300046 A GT200300046 A GT 200300046A GT 200300046 A GT200300046 A GT 200300046A GT 200300046 A GT200300046 A GT 200300046A
Authority
GT
Guatemala
Prior art keywords
useful
tienopiridins
antiangiogen
indolil
procedures
Prior art date
Application number
GT200300046A
Other languages
English (en)
Inventor
Robert Steven Kania
William Henry Romines Iii
Stephan James Cripps
Mingying He
Jihong Lou
Ru Zhou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200300046A publication Critical patent/GT200300046A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE FORMULA GENERAL I EN DONDE Y,X,R1,R11, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON UTILES COMO INHIBIDORES SELECTIVOS DEL DESARROLLO DE CELULAS CANCERIGENAS POR LO QUE SON UTILIZABLES EN CANCER DE DIVERSOS TIPOS.
GT200300046A 2002-03-01 2003-02-27 Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso GT200300046A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36095202P 2002-03-01 2002-03-01

Publications (1)

Publication Number Publication Date
GT200300046A true GT200300046A (es) 2003-10-10

Family

ID=27789048

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200300046A GT200300046A (es) 2002-03-01 2003-02-27 Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso

Country Status (15)

Country Link
US (1) US6833456B2 (es)
EP (1) EP1483268A2 (es)
JP (1) JP2005527511A (es)
AR (1) AR040398A1 (es)
AU (1) AU2003206068A1 (es)
BR (1) BR0308162A (es)
CA (1) CA2478050A1 (es)
GT (1) GT200300046A (es)
HN (1) HN2003000080A (es)
MX (1) MXPA04008403A (es)
PA (1) PA8568101A1 (es)
PE (1) PE20030944A1 (es)
TW (1) TW200306193A (es)
UY (1) UY27685A1 (es)
WO (1) WO2003074529A2 (es)

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WO2007107005A1 (en) * 2006-03-22 2007-09-27 Methylgene, Inc. Inhibitors of protein tyrosine kinase activity
JP2009539878A (ja) * 2006-06-08 2009-11-19 アレイ バイオファーマ、インコーポレイテッド キノリン化合物および使用方法
BRPI0908573A2 (pt) 2008-03-05 2012-12-25 Methylgene Inc inibidores da atividade de proteÍna tirosina quinase
KR101126736B1 (ko) * 2008-11-27 2012-04-12 주식회사 레고켐 바이오사이언스 티로신 키나아제 저해 화합물, 이의 이성질체 또는 이의 약학적으로 허용가능한 염 및 이를 포함하는 약학적 조성물
CA2806701A1 (en) 2010-07-29 2012-02-02 Bial - Portela & Ca, S.A. Process for the synthesis of substituted urea compounds
WO2013012918A1 (en) 2011-07-19 2013-01-24 Infinity Pharmaceuticals Inc. Heterocyclic compounds and uses thereof
US10093660B2 (en) 2013-12-04 2018-10-09 Evotec Internatonal Gmbh Sulfoximine substituted quinazolines for pharmaceutical compositions
TN2016000452A1 (en) 2014-04-25 2018-04-04 Pfizer Heteroaromatic compounds and their use as dopamine d1 ligands.
CN115746017B (zh) * 2022-11-30 2024-06-07 英维沃化工科技(广州)有限公司 一种噻吩并嘧啶类化合物及其制备方法和应用
CN116082214A (zh) * 2023-02-24 2023-05-09 常州大学 一种2-芳基-3-叔丁基吲哚类化合物、制备方法及其应用

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Also Published As

Publication number Publication date
EP1483268A2 (en) 2004-12-08
WO2003074529A2 (en) 2003-09-12
BR0308162A (pt) 2004-12-07
UY27685A1 (es) 2003-10-31
WO2003074529A3 (en) 2003-12-24
US6833456B2 (en) 2004-12-21
AU2003206068A8 (en) 2003-09-16
AU2003206068A1 (en) 2003-09-16
CA2478050A1 (en) 2003-09-12
HN2003000080A (es) 2004-05-05
TW200306193A (en) 2003-11-16
AR040398A1 (es) 2005-04-06
MXPA04008403A (es) 2004-11-26
JP2005527511A (ja) 2005-09-15
US20040019065A1 (en) 2004-01-29
PA8568101A1 (es) 2003-11-12
PE20030944A1 (es) 2003-11-08

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