GR900100537A - Βελτιωμένη χλωρίωση 6-εστέρος ζακχαρόζης. - Google Patents
Βελτιωμένη χλωρίωση 6-εστέρος ζακχαρόζης.Info
- Publication number
- GR900100537A GR900100537A GR900100537A GR900100537A GR900100537A GR 900100537 A GR900100537 A GR 900100537A GR 900100537 A GR900100537 A GR 900100537A GR 900100537 A GR900100537 A GR 900100537A GR 900100537 A GR900100537 A GR 900100537A
- Authority
- GR
- Greece
- Prior art keywords
- ester
- sucrose
- produce
- reaction mixture
- product
- Prior art date
Links
- 229960004793 sucrose Drugs 0.000 abstract 5
- 229930006000 Sucrose Natural products 0.000 abstract 4
- 239000005720 sucrose Substances 0.000 abstract 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 3
- 239000011541 reaction mixture Substances 0.000 abstract 3
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- 241000193830 Bacillus <bacterium> Species 0.000 abstract 1
- 150000003841 chloride salts Chemical class 0.000 abstract 1
- 238000005660 chlorination reaction Methods 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003511 tertiary amides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Μια μέ?οδος δια την χλωρίωση των 6-εστέρων της σακχαρόζης προς παραγωγή 6-εστέρων 6',4,1' -τριχλωριο σακχαρόζης η οποία περιλαμβάνει τας βα?μίδας: (α) Προσ?ήκη τουλάχιστον 67 μοριακών ισοδυνάμων ενός χλωριδίου οξέος εις ένα μίγμα αντιδράσεως που περιέχει ένα 6- εστέρα σακχαρόζης και μια τριτοταγή αμίδη προς σχηματισμό κατ' αρχάς ενός άλατος χλωριούχου χλωριοφορμιμινίου το οποίο εν συνεχεία σχηματίζει ένα σύμπλοκο με τις υδροξυλομάδες του 6-εστέρος της σακχαρόζης. (β) υποβολή του μίγματος αντιδράσεως του προιόντος της βα?μίδος (α) εις ηυξημένη ?ερμοκρασία όχι μεγαλυτέρα των περίπου 85 βα?μών Κελσίου επί χρονικό διάστημα επαρκές ώστε να παραχ?εί ένα μίγμα χλωριωμένων προιόντων 6-εστέρος σακχαρόζης που αποτελείται κυρίως από 6-εστέρα 6'- χλωριοσακχαρόζη, 6-εστέρα 4,6'-διχλωριοσακχαρόζης και 6- εστέρα 1',6'-διχλωριοσακχαρόζης και (γ) υποβολή του μίγματος αντιδράσεως του προιόντος της βα?μίδος (β) εις ηυξημένη ?ερμοκρασία όχι μεγαλυτέρα των περίπου 125 βα?μών Κελσίου επί χρονικό διάστημα επαρκές δια να παραχ?εί ένα χλωριωμένο προιόν που αποτελείται κυρίως από 6-εστέρα της 1',4,6'-τριχλωριοσακχαρόζης. ω
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/382,147 US4980463A (en) | 1989-07-18 | 1989-07-18 | Sucrose-6-ester chlorination |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GR900100537A true GR900100537A (el) | 1991-12-10 |
| GR1002037B GR1002037B (en) | 1995-10-31 |
Family
ID=23507711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR900100537A GR1002037B (en) | 1989-07-18 | 1990-07-12 | Improvents relating to the sacharose 6-estere chlorization |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4980463A (el) |
| EP (1) | EP0409549B1 (el) |
| JP (1) | JP3183506B2 (el) |
| KR (1) | KR0144344B1 (el) |
| AR (1) | AR247401A1 (el) |
| AT (1) | ATE133175T1 (el) |
| AU (1) | AU625908B2 (el) |
| CA (1) | CA2021632C (el) |
| DE (1) | DE69024868T2 (el) |
| DK (1) | DK0409549T3 (el) |
| ES (1) | ES2088973T3 (el) |
| FI (1) | FI95802C (el) |
| GR (1) | GR1002037B (el) |
| IE (1) | IE69961B1 (el) |
| IL (1) | IL94994A (el) |
| MX (1) | MX164442B (el) |
| NO (1) | NO175532C (el) |
| NZ (1) | NZ234468A (el) |
| PE (1) | PE21591A1 (el) |
| PH (1) | PH26799A (el) |
| PT (1) | PT94719B (el) |
| RU (1) | RU1836377C (el) |
| TR (1) | TR28705A (el) |
| TW (1) | TW219939B (el) |
| YU (1) | YU47948B (el) |
| ZA (1) | ZA905615B (el) |
Families Citing this family (90)
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| US5136031A (en) * | 1990-07-09 | 1992-08-04 | Tate & Lyle Public Limited Company | Chlorination of sugars |
| US5470969A (en) * | 1990-08-27 | 1995-11-28 | Mcneil-Ppc, Inc. | Catalyzed sucrose-6-ester process |
| GB9110931D0 (en) * | 1991-05-21 | 1991-07-10 | Tate & Lyle Plc | Process for the preparation of sucrose 6-esters |
| US5298611A (en) * | 1993-03-12 | 1994-03-29 | Mcneil-Ppc, Inc. | Sucralose pentaester production |
| WO1996001832A1 (en) | 1994-07-11 | 1996-01-25 | The United States Of America, Represented By The Secretary Of The Department Of Agriculture | Chemically synthesized sugar esters for the control of soft-bodied arthropods |
| US6608039B1 (en) | 1994-07-11 | 2003-08-19 | The United States Of America As Represented By The Secretary Of Agriculture | Chemically synthesized sugar esters for the control of soft-bodied arthropods |
| RU2155769C2 (ru) * | 1994-10-17 | 2000-09-10 | Макнейл - Ппс, Инк. | Получение сукралозы без промежуточного выделения кристаллического сукралоза-6-эфира |
| US5498709A (en) | 1994-10-17 | 1996-03-12 | Mcneil-Ppc, Inc. | Production of sucralose without intermediate isolation of crystalline sucralose-6-ester |
| KR100405203B1 (ko) * | 1996-05-23 | 2004-02-14 | 비앤티엔지니어링(주) | 암거배수로관 |
| AU6167598A (en) * | 1997-02-13 | 1998-09-08 | Mcneil-Ppc, Inc. | Chromatographic purification of chlorinated sucrose |
| WO1999060006A1 (en) * | 1998-05-15 | 1999-11-25 | Zhbankov Rostislav G | Method of preparation 4,1´,6´-trichloro-4,1´,6´-trideoxygalactosucrose |
| DE19924770A1 (de) * | 1999-05-29 | 2000-12-21 | Buna Sow Leuna Olefinverb Gmbh | Verfahren zur Herstellung von Polyetherpolyolen aus Polysacchariden und deren Verwendung für die Herstellung von PUR-Schäumen |
| US6500973B2 (en) | 2000-06-02 | 2002-12-31 | Eastman Chemical Company | Extractive solution crystallization of chemical compounds |
| ATE387457T1 (de) * | 2000-08-25 | 2008-03-15 | Eastman Chem Co | Verfahren zur herstellung von disaccharid und trisaccharid c6-c12 fettsäure-estern mit hohem alpha gehalt und materialien davon |
| US6667397B2 (en) * | 2000-08-25 | 2003-12-23 | Eastman Chemical Company | Methods of preparing disaccharide and trisaccharide C6-C12 fatty acid esters with high alpha content and materials therefrom |
| US6646121B2 (en) | 2000-11-17 | 2003-11-11 | Mcneil-Ppc, Inc. | Sucralose composition and process for its preparation |
| US6998480B2 (en) | 2002-03-08 | 2006-02-14 | Tate & Lyle Public Limited Company | Process for improving sucralose purity and yield |
| US7049435B2 (en) | 2002-03-08 | 2006-05-23 | Tate & Lyle Public Limited Company | Extractive methods for purifying sucralose |
| US6890581B2 (en) * | 2002-04-05 | 2005-05-10 | Tate & Lyle Public Limited Company | Methods for buffer stabilized aqueous deacylation |
| US20040170735A2 (en) * | 2002-04-05 | 2004-09-02 | Mcneil-Ppc, Inc. | Methods and compositions for altering the sweetness delivery profile of sucralose |
| US20040086605A1 (en) * | 2002-10-30 | 2004-05-06 | Sox Thomas E. | Composition for delivering a high intensity sweetener |
| US6943248B2 (en) | 2003-04-30 | 2005-09-13 | Tate & Lyle Public Limited Company | Crystalline form of sucralose, and method for producing it |
| CN1176094C (zh) * | 2003-05-23 | 2004-11-17 | 广东省食品工业研究所 | 一种三氯蔗糖的合成方法 |
| CA2558683A1 (en) * | 2004-03-05 | 2005-09-22 | Sunil Srivastava | High-intensity sweetener-polyol compositions |
| DE602004032578D1 (de) * | 2004-03-19 | 2011-06-16 | Vb Medicare Pvt Ltd | Verbessertes verfahren zur herstellung von chlorierter saccharose |
| US20050214425A1 (en) * | 2004-03-23 | 2005-09-29 | Roma Vazirani | Sugar substitute prepared with nutritive and high-intensity sweeteners |
| US20080051574A1 (en) * | 2004-12-10 | 2008-02-28 | Rakesh Ratnam | Control of Ph By Direct Addition of Carbonates and Bicarbonates During Concentration of Organics Solvent Extracts of 6-Acetyl-4,1',6' Trichlorogalactosucrose and 4,1',6' trichlorogalactosucrose |
| CN101098972A (zh) * | 2004-12-10 | 2008-01-02 | 法马德医疗保险私人有限公司 | 硅烷化硅胶色谱纯化6-乙酰基-4,1',6'三氯半乳蔗糖和4,1',6'三氯半乳蔗糖的改良方法 |
| WO2006061855A2 (en) * | 2004-12-10 | 2006-06-15 | Pharmed Medicare Private Limited | Salts assisted selective extraction of 6-acetyl-4.1', 6' trichlorogalactosucrose and 4, 1 ', 6' trichlorogalactosucrose from aqueous reaction mixture |
| CN101175762A (zh) * | 2005-01-03 | 2008-05-07 | 法马德医疗保险私人有限公司 | 通过氯化试剂的共-加入进行蔗糖-6-酯的氯化 |
| US20060188629A1 (en) * | 2005-01-21 | 2006-08-24 | Greg Liesen | Method for the purification of sucralose |
| CN101166748A (zh) * | 2005-02-22 | 2008-04-23 | 法马德医疗保险私人有限公司 | 在生产氯化蔗糖、其前体和衍生物过程的不同步骤中的分子分离方法 |
| US20060205936A1 (en) * | 2005-03-14 | 2006-09-14 | Sl Laboratories, Llc | Chlorination of Sucrose-6-esters |
| US20060247180A1 (en) * | 2005-04-29 | 2006-11-02 | Bergey James L | Purgative composition and uses thereof |
| BRPI0612344A2 (pt) * | 2005-05-04 | 2010-11-03 | Pharmed Medicare Pvt Ltd | processo de obtenção de oxicloreto de fósforo e processo de cloração de um substrato utilizando o oxicloreto de fósforo obtido |
| WO2007026377A2 (en) * | 2005-05-04 | 2007-03-08 | Pharmed Medicare Private Limited | Synthesis of vilsmeier haack reagent from di (trichlo-romethyl) carbonate for chlorination reaction. |
| US20060276639A1 (en) * | 2005-06-01 | 2006-12-07 | Healthy Brands, Llc | Conversion of sucralose-6-ester to sucralose |
| GB2441917A (en) * | 2005-06-01 | 2008-03-19 | Pharmed Medicare Pvt Ltd | Method for purification of chlorinated sucrose derivatives by solvent extraction |
| US20100160625A1 (en) * | 2005-09-22 | 2010-06-24 | Rakesh Ratnam | Novel Preparation of 6-O-Acyl Chlorosucrose from Anhydrous Cholorinated Reaction Mass |
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| CN100420697C (zh) * | 2006-08-30 | 2008-09-24 | 河北苏科瑞科技有限公司 | 一种制备蔗糖-6-有机酸酯的方法 |
| US8258291B2 (en) * | 2006-10-25 | 2012-09-04 | Mamtek International Limited | Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC) |
| US20080103295A1 (en) * | 2006-10-25 | 2008-05-01 | David Losan Ho | Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst |
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| CN101260127B (zh) * | 2007-03-06 | 2011-04-20 | 盐城捷康三氯蔗糖制造有限公司 | 由三氯蔗糖-6-乙酯脱乙酰基合成三氯蔗糖的方法 |
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| US20080300401A1 (en) * | 2007-06-04 | 2008-12-04 | Polymed Therapeutics, Inc. | Novel chlorination process for preparing sucralose |
| US8436156B2 (en) * | 2008-01-04 | 2013-05-07 | Tate & Lyle Technology Limited | Method for the production of sucralose |
| US7932380B2 (en) * | 2008-03-06 | 2011-04-26 | Wanhe International (Group) Co. Ltd. | Process for the preparation of sucralose |
| US8557976B2 (en) * | 2008-03-13 | 2013-10-15 | Tate & Lyle Technology Limited | Microbial consortia and methods for their use |
| KR20100130219A (ko) * | 2008-03-20 | 2010-12-10 | 테이트 앤드 라일 테크놀러지 리미티드 | 3급 아미드 용매로부터 산을 제거하는 방법 |
| US8436157B2 (en) * | 2008-03-26 | 2013-05-07 | Tate & Lyle Technology Limited | Method for the production of sucralose |
| AR071134A1 (es) * | 2008-04-03 | 2010-05-26 | Tate & Lyle Technology Ltd | Cristalizacion de sucralosa a partir de chorros que contienen sucralosa |
| US20090259036A1 (en) * | 2008-04-03 | 2009-10-15 | Tate & Lyle Technology Limited | Extraction of less polar impurities from sucralose containing aqueous feed streams |
| JP5653341B2 (ja) * | 2008-04-03 | 2015-01-14 | テート アンド ライル テクノロジー リミテッド | スクラロース抽出効率に対する炭水化物濃度の影響 |
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| US7862744B2 (en) * | 2008-07-23 | 2011-01-04 | Mamtek International Limited | Methods and systems for preparing materials for sucralose production |
| US20100022765A1 (en) * | 2008-07-23 | 2010-01-28 | David Losan Ho | Methods for extracting and purifying sucralose intermediate |
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| GB2469157B (en) * | 2009-03-30 | 2011-07-06 | John Kerr | Process for removing dimethylamine during sucralose production |
| GB2469158B (en) | 2009-03-31 | 2011-09-28 | Peter J Seaberg | Base-assisted formation of tin-sucrose adducts |
| GB2471348B (en) * | 2009-06-22 | 2011-12-14 | Tate & Lyle Technology Ltd | A method for producing sucralose-6-acylate |
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| ES2551585T3 (es) * | 2010-08-25 | 2015-11-20 | Davuluri, Ramamohan Rao | Procedimiento mejorado para la preparación de Sugammadex |
| AU2011332011B2 (en) * | 2010-11-23 | 2017-01-12 | Lexington Pharmaceuticals Laboratories, Llc | Low temperature chlorination of carbohydrates |
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| US8884004B2 (en) | 2011-09-02 | 2014-11-11 | Divi's Laboratories, Ltd. | Process for the preparation of sucralose |
| HUE027876T2 (en) | 2011-10-14 | 2016-10-28 | Lexington Pharmaceuticals Laboratories Llc | Carbohydrate chlorination and carbohydrate derivatives |
| CN102964396B (zh) * | 2012-10-26 | 2015-11-18 | 溧阳维信生物科技有限公司 | 一种三氯蔗糖-6-乙酯重结晶的方法 |
| JP6109531B2 (ja) * | 2012-11-02 | 2017-04-05 | 第一工業製薬株式会社 | 溶媒の除去方法 |
| CN103145772A (zh) * | 2013-03-26 | 2013-06-12 | 山东金城柯瑞化学有限公司 | 三氯蔗糖的制备方法 |
| CN105829332B (zh) | 2013-12-16 | 2018-10-02 | 塔特和莱利技术有限公司 | 蔗糖-6-酯的氯化 |
| CN106573949B (zh) * | 2014-08-08 | 2019-03-15 | 塔特和莱利技术有限公司 | 蔗糖-6-酯的氯化 |
| CN104387427A (zh) * | 2014-10-30 | 2015-03-04 | 安徽金禾实业股份有限公司 | 一种三氯蔗糖的生产方法 |
| GB2536480B (en) | 2015-03-17 | 2019-09-04 | Tate & Lyle Tech Ltd | DMF Distillation |
| CN105131050B (zh) * | 2015-07-22 | 2018-07-31 | 青岛科技大学 | 一种氯化剂的制备方法及其制备三氯蔗糖的方法 |
| CN105859802B (zh) * | 2016-05-14 | 2019-02-12 | 广西科技大学 | 一种三氯蔗糖的结晶和纯化方法 |
| GB2551591B (en) | 2016-06-23 | 2019-08-07 | Tate & Lyle Tech Ltd | Liquid-liquid extraction of DMF |
| WO2022067621A1 (zh) | 2020-09-30 | 2022-04-07 | 安徽金禾实业股份有限公司 | 三氯蔗糖的纯化方法 |
| CN113699196A (zh) * | 2021-08-17 | 2021-11-26 | 安徽金禾实业股份有限公司 | 一种蔗糖-6-乙酸酯的无水酶法催化合成方法 |
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|---|---|---|---|---|
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| EP0130054A2 (en) * | 1983-06-21 | 1985-01-02 | TATE & LYLE PUBLIC LIMITED COMPANY | Novel Fructosyltransferase, process for the preparation of Fructosyl disaccharides, and a novel halosucrose |
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| EP0031651B1 (en) * | 1979-12-20 | 1983-03-23 | TATE & LYLE PUBLIC LIMITED COMPANY | Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose |
| US4345933A (en) * | 1980-01-28 | 1982-08-24 | Velsicol Chemical Corporation | Sucrose ester of 2-methoxy-3,6-dichlorobenzoic acid |
| US4291158A (en) * | 1980-01-28 | 1981-09-22 | Velsicol Chemical Corporation | Sucrose ester of 2-methoxy-3,6-dichlorobenzoic acid |
| IE55619B1 (en) * | 1982-09-13 | 1990-11-21 | Tate & Lyle Plc | 6-derivatives of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose |
| GB8622345D0 (en) * | 1986-09-17 | 1986-10-22 | Tate & Lyle Plc | Sucrose derivatives |
-
1989
- 1989-07-18 US US07/382,147 patent/US4980463A/en not_active Expired - Lifetime
-
1990
- 1990-07-06 IL IL9499490A patent/IL94994A/en unknown
- 1990-07-06 PH PH40800A patent/PH26799A/en unknown
- 1990-07-11 NZ NZ234468A patent/NZ234468A/en unknown
- 1990-07-12 GR GR900100537A patent/GR1002037B/el not_active IP Right Cessation
- 1990-07-16 PE PE1990172224A patent/PE21591A1/es not_active Application Discontinuation
- 1990-07-16 CA CA002021632A patent/CA2021632C/en not_active Expired - Lifetime
- 1990-07-17 DE DE69024868T patent/DE69024868T2/de not_active Expired - Lifetime
- 1990-07-17 IE IE260390A patent/IE69961B1/en not_active IP Right Cessation
- 1990-07-17 JP JP18732890A patent/JP3183506B2/ja not_active Expired - Fee Related
- 1990-07-17 ZA ZA905615A patent/ZA905615B/xx unknown
- 1990-07-17 AR AR90317395A patent/AR247401A1/es active
- 1990-07-17 ES ES90307784T patent/ES2088973T3/es not_active Expired - Lifetime
- 1990-07-17 AU AU59069/90A patent/AU625908B2/en not_active Expired
- 1990-07-17 NO NO903190A patent/NO175532C/no not_active IP Right Cessation
- 1990-07-17 RU SU4830726A patent/RU1836377C/ru active
- 1990-07-17 AT AT90307784T patent/ATE133175T1/de not_active IP Right Cessation
- 1990-07-17 EP EP90307784A patent/EP0409549B1/en not_active Expired - Lifetime
- 1990-07-17 DK DK90307784.0T patent/DK0409549T3/da active
- 1990-07-17 PT PT94719A patent/PT94719B/pt not_active IP Right Cessation
- 1990-07-17 FI FI903603A patent/FI95802C/fi not_active IP Right Cessation
- 1990-07-18 YU YU141190A patent/YU47948B/sh unknown
- 1990-07-18 TR TR00678/90A patent/TR28705A/xx unknown
- 1990-07-18 KR KR1019900010857A patent/KR0144344B1/ko not_active Expired - Fee Related
- 1990-07-18 MX MX21634A patent/MX164442B/es unknown
- 1990-07-26 TW TW079106171A patent/TW219939B/zh active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0015757A1 (en) * | 1979-03-09 | 1980-09-17 | TATE & LYLE PATENT HOLDINGS LIMITED | Process for the preparation of chlorodeoxysugars |
| EP0043649A1 (en) * | 1980-07-08 | 1982-01-13 | TATE & LYLE PUBLIC LIMITED COMPANY | Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (TGS) |
| EP0130054A2 (en) * | 1983-06-21 | 1985-01-02 | TATE & LYLE PUBLIC LIMITED COMPANY | Novel Fructosyltransferase, process for the preparation of Fructosyl disaccharides, and a novel halosucrose |
Non-Patent Citations (3)
| Title |
|---|
| ANGEW. CHEM. INTERNAT. EDIT., vol. 12, no. 10, 1973, pages 806-818; H.G. VIEHE et al.: "The chemistry of dichloromethylenammomium salts" * |
| CLAIMS SEARCHED: ALL * |
| J. CHEM. SOC., PERKIN I, 1976, pages 754-757; D.R. HEPBURN et al.: "Factors in the formation of isomerically and optically pure alkyl halides. Part XI. Vilsmeier reagents for the replacement of a hydroxy-group by chlorine or bromine" * |
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