GR1000989B - Μεθοδος παρασκευης συνθεσεως για θεραπεια οστεοπορωσης και ορμονικης ανισορροπιας. - Google Patents
Μεθοδος παρασκευης συνθεσεως για θεραπεια οστεοπορωσης και ορμονικης ανισορροπιας.Info
- Publication number
- GR1000989B GR1000989B GR910100192A GR910100192A GR1000989B GR 1000989 B GR1000989 B GR 1000989B GR 910100192 A GR910100192 A GR 910100192A GR 910100192 A GR910100192 A GR 910100192A GR 1000989 B GR1000989 B GR 1000989B
- Authority
- GR
- Greece
- Prior art keywords
- treatment
- ormonic
- ansororopia
- hospitality
- estrogen
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 3
- 229940011871 estrogen Drugs 0.000 abstract 3
- 239000000262 estrogen Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 2
- 206010065687 Bone loss Diseases 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 abstract 1
- 229910001634 calcium fluoride Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000003054 hormonal effect Effects 0.000 abstract 1
- 229940074371 monofluorophosphate Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Inorganic materials [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 abstract 1
- 230000009747 swallowing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/16—Fluorine compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Ενα φάρμακο για παροχή ιόντος φθορίου για την πρόληψη και θεραπεία ασθένειας απώλειας οστού, μαζί με μία ουσία που περιέχει οιστρογόνο όχι μόνο για θεραπεία ορμονικής ανισορροπίας αλλά και για να λαμβάνεται πιο πλεονεκτική χρήση ιόντος φθορίου στο σώμα. Η δοσολογία είναι ένας τροχίσκος, δισκίο ή κάψουλα, που περιέχει από 20 έως 100 χιλιοστογραμμάρια μονοφθοροφωσφορικού και περαιτέρω περιλαμβάνει μία ουσία που περιέχει οιστρογόνο και ένα μηχανισμό βραδείας απελευθέρωσης για ελεγχόμενη απελευθέρωση του ιόντος φθορίου και του οιστρογόνου, σε περίοδο από τέσσερις έως οκτώ ώρες μετά την κατάποση. Μέχρι δέκα τοις εκατό φθοριούχου νατρίου ή/και ασβεστίου μπορεί να προστίθεται. ω
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/519,088 US5013728A (en) | 1990-05-04 | 1990-05-04 | Composition for treating osteoporosis and hormonal imbalance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GR910100192A GR910100192A (en) | 1992-07-30 |
| GR1000989B true GR1000989B (el) | 1993-03-31 |
Family
ID=24066774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR910100192A GR1000989B (el) | 1990-05-04 | 1991-05-03 | Μεθοδος παρασκευης συνθεσεως για θεραπεια οστεοπορωσης και ορμονικης ανισορροπιας. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5013728A (el) |
| EP (1) | EP0455503A1 (el) |
| JP (1) | JPH04225921A (el) |
| AU (1) | AU647111B2 (el) |
| BR (1) | BR9101787A (el) |
| CA (1) | CA2041799A1 (el) |
| FI (1) | FI912160L (el) |
| GR (1) | GR1000989B (el) |
| IE (1) | IE911514A1 (el) |
| MX (1) | MX166220B (el) |
| PT (1) | PT97543A (el) |
| ZA (1) | ZA913184B (el) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5776493A (en) * | 1989-07-14 | 1998-07-07 | Alza Corporation | Oral osmotic device for delivery of nystatin with hydrogel driving member |
| US5153005A (en) * | 1990-12-11 | 1992-10-06 | Colgate-Palmolive Company | Composition and method for preventing fluorosis |
| DE59209889D1 (de) * | 1991-09-13 | 2001-03-01 | David J Baylink | Knochenwachstumsfördernde zusammensetzung |
| ES2170069T3 (es) * | 1992-06-22 | 2002-08-01 | Bone Care Int Inc | 1-alfa-hidroxiprevitamina d para administracion oral. |
| US5795882A (en) * | 1992-06-22 | 1998-08-18 | Bone Care International, Inc. | Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations |
| US5573776A (en) * | 1992-12-02 | 1996-11-12 | Alza Corporation | Oral osmotic device with hydrogel driving member |
| EP0676951B1 (en) * | 1992-12-29 | 2002-04-17 | HOLICK, Michael F | Use of vitamin d glycosides for the treatment or prevention of osteoporosis |
| AU4825200A (en) * | 1999-05-07 | 2000-11-21 | Board Of Regents, The University Of Texas System | Oral steroidal hormone compositions and methods of use |
| ES2192136B1 (es) * | 2002-01-04 | 2005-03-16 | Italfarmaco, S.A. | Composiciones farmaceuticas para el tratamiento o prevencion de la osteoporosis. |
| US7138394B2 (en) * | 2002-09-27 | 2006-11-21 | Alpharx Inc. | Vehicle for topical delivery of anti-inflammatory compounds |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3287219A (en) * | 1963-08-05 | 1966-11-22 | Charles J Nemanick | Method of healing bone fractures |
| DE2630326C2 (de) * | 1976-07-06 | 1983-07-21 | "Gebro" G. Broschek Kg, Chemisch-Pharmazeutische Fabrik, 6391 Fieberbrunn, Tirol | Präparat zur Behandlung der Osteoporose und seine Herstellung |
| US4101668A (en) * | 1977-05-10 | 1978-07-18 | Bristol-Myers Company | Antiosteoporotic agents |
| US4185108A (en) * | 1977-05-10 | 1980-01-22 | Westwood Pharmaceuticals Inc. | Antiosteoporotic agents |
| IT1106130B (it) * | 1977-06-13 | 1985-11-11 | Merck & Co Inc | Derivati di 24-deidrovitamina d3 e loro preparazione |
| US4220552A (en) * | 1978-06-05 | 1980-09-02 | The United States Of America As Represented By The Department Of Health, Education & Welfare | Method of producing delayed release of sodium fluoride |
| DE2922671C2 (de) * | 1979-06-02 | 1982-08-19 | Battelle-Institut E.V., 6000 Frankfurt | Zahnpflege- und Zahnreinigungsmittel |
| AU532512B2 (en) * | 1979-09-07 | 1983-10-06 | Upjohn and Horton | Anti-allergenic compounds for bone mineral resorption |
| FR2542199B1 (fr) * | 1983-03-11 | 1986-01-10 | Rizhskij Med Inst | Medicament pour le traitement de la carie dentaire |
| US4726952A (en) * | 1983-08-11 | 1988-02-23 | Mission Pharmacal | Slow-release sodium fluoride tablet, method of making, and method of treatment of osteoporosis |
| AU568433B2 (en) * | 1984-04-30 | 1987-12-24 | Procter & Gamble Company, The | Treating osteoporosis |
| US4851228A (en) * | 1984-06-20 | 1989-07-25 | Merck & Co., Inc. | Multiparticulate controlled porosity osmotic |
| GB8519310D0 (en) * | 1985-07-31 | 1985-09-04 | Zyma Sa | Granular active substances |
| GB8521494D0 (en) * | 1985-08-29 | 1985-10-02 | Zyma Sa | Controlled release tablet |
| US4859467A (en) * | 1986-09-25 | 1989-08-22 | Colgate-Palmotive Company | Sustained release fluoride composition |
| US4861590A (en) * | 1986-09-25 | 1989-08-29 | Colgate-Palmolive Company | Sustained release fluoride and calcium composition |
| US4814183A (en) * | 1987-08-31 | 1989-03-21 | Merck & Co., Inc. | Device for the controlled release of drugs with Donnan-like modulation by charged insoluble resins |
| US4795644A (en) * | 1987-08-03 | 1989-01-03 | Merck & Co., Inc. | Device for pH independent release of drugs through the Donnan-like influence of charged insoluble resins |
| EP0322020A1 (en) * | 1987-12-22 | 1989-06-28 | Akzo N.V. | Pharmaceutical dosage unit for treating climacteric complaints and osteoporosis |
| WO1989009058A1 (en) * | 1988-03-25 | 1989-10-05 | Akzo N.V. | Pharmaceutical preparation containing a fluoride salt |
-
1990
- 1990-05-04 US US07/519,088 patent/US5013728A/en not_active Expired - Fee Related
-
1991
- 1991-04-24 AU AU75914/91A patent/AU647111B2/en not_active Ceased
- 1991-04-26 MX MX025556A patent/MX166220B/es unknown
- 1991-04-26 ZA ZA913184A patent/ZA913184B/xx unknown
- 1991-05-02 PT PT97543A patent/PT97543A/pt not_active Application Discontinuation
- 1991-05-03 GR GR910100192A patent/GR1000989B/el unknown
- 1991-05-03 IE IE151491A patent/IE911514A1/en unknown
- 1991-05-03 CA CA002041799A patent/CA2041799A1/en not_active Abandoned
- 1991-05-03 BR BR919101787A patent/BR9101787A/pt not_active Application Discontinuation
- 1991-05-03 FI FI912160A patent/FI912160L/fi not_active Application Discontinuation
- 1991-05-03 EP EP91304021A patent/EP0455503A1/en not_active Withdrawn
- 1991-05-07 JP JP3101491A patent/JPH04225921A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2041799A1 (en) | 1991-11-05 |
| BR9101787A (pt) | 1991-12-17 |
| ZA913184B (en) | 1992-12-30 |
| FI912160A7 (fi) | 1991-11-05 |
| US5013728A (en) | 1991-05-07 |
| FI912160A0 (fi) | 1991-05-03 |
| JPH04225921A (ja) | 1992-08-14 |
| PT97543A (pt) | 1992-01-31 |
| MX166220B (es) | 1992-12-23 |
| EP0455503A1 (en) | 1991-11-06 |
| GR910100192A (en) | 1992-07-30 |
| AU7591491A (en) | 1991-11-07 |
| FI912160L (fi) | 1991-11-05 |
| IE911514A1 (en) | 1991-11-06 |
| AU647111B2 (en) | 1994-03-17 |
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