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GR1000611B - METHOD FOR THE EXAMINATION OF CYCLOSPORINE OFFTHALMIC SYNTHESIS. - Google Patents

METHOD FOR THE EXAMINATION OF CYCLOSPORINE OFFTHALMIC SYNTHESIS.

Info

Publication number
GR1000611B
GR1000611B GR890100690A GR890100690A GR1000611B GR 1000611 B GR1000611 B GR 1000611B GR 890100690 A GR890100690 A GR 890100690A GR 890100690 A GR890100690 A GR 890100690A GR 1000611 B GR1000611 B GR 1000611B
Authority
GR
Greece
Prior art keywords
cyclosporine
eye
offthalmic
examination
synthesis
Prior art date
Application number
GR890100690A
Other languages
Greek (el)
Other versions
GR890100690A (en
Inventor
Ronald Edward Dr Peeples
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of GR890100690A publication Critical patent/GR890100690A/en
Publication of GR1000611B publication Critical patent/GR1000611B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Νέες οφθαλμικές συνθέσεις περιλαμβάνοντας μια κυκλοσπορίνη π.χ. Κικλοσπορίνη, ως ενεργό συστατικό και φυτικό λάδι κατά προτίμηση αραβοσιτέλαιο και μια κατά προτίμηση λευκή βαζελίνη ως φορέα. Οι συνθέσεις είναι χρήσιμες για τοπική οφθαλμική εφαρμογή κατά την θεραπεία νόσων ή καταστάσεων που προσβάλλουν τον οφθαλμό, ιδιαίτερα εσωτερικές δομές ή ιστούς του οφθαλμού, καθώς και περιβάλλοντα ή συνδεδeμένα όργανα ή ιστούς. ωNew eye compositions including a cyclosporine e.g. Cyclosporine as the active ingredient and vegetable oil preferably corn oil and preferably a white Vaseline as a carrier. The compositions are useful for topical ophthalmic application in the treatment of diseases or conditions that affect the eye, especially internal structures or tissues of the eye, as well as surrounding or associated organs or tissues. ω

GR890100690A 1988-10-26 1989-10-25 METHOD FOR THE EXAMINATION OF CYCLOSPORINE OFFTHALMIC SYNTHESIS. GR1000611B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26286688A 1988-10-26 1988-10-26

Publications (2)

Publication Number Publication Date
GR890100690A GR890100690A (en) 1990-11-29
GR1000611B true GR1000611B (en) 1992-08-31

Family

ID=22999400

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100690A GR1000611B (en) 1988-10-26 1989-10-25 METHOD FOR THE EXAMINATION OF CYCLOSPORINE OFFTHALMIC SYNTHESIS.

Country Status (23)

Country Link
JP (1) JPH02164830A (en)
KR (1) KR900005973A (en)
AU (1) AU626928B2 (en)
BE (1) BE1003578A4 (en)
CA (1) CA2001502A1 (en)
CH (1) CH679210A5 (en)
DE (1) DE3935517A1 (en)
DK (1) DK531289A (en)
ES (1) ES2020032A6 (en)
FI (1) FI895064A7 (en)
FR (1) FR2638089A1 (en)
GB (1) GB2224205B (en)
GR (1) GR1000611B (en)
HU (1) HU203046B (en)
IL (1) IL92120A (en)
LU (1) LU87613A1 (en)
MY (1) MY106271A (en)
NL (1) NL8902657A (en)
NO (1) NO894266L (en)
NZ (1) NZ231131A (en)
PT (1) PT92120B (en)
SE (1) SE8903583L (en)
ZA (1) ZA898140B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 Pharmaceutical composition containing cyclosporin
CA2002147A1 (en) * 1988-11-07 1990-05-07 Shuichi Morikawa Production process for polyimide fibers
US5540931A (en) * 1989-03-03 1996-07-30 Charles W. Hewitt Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
FR2670629B1 (en) * 1990-12-17 1995-03-10 Moving Magnet Tech ROTARY SINGLE - PHASE ELECTROMAGNETIC ACTUATOR.
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
ZA927277B (en) * 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
DK0642332T3 (en) * 1992-05-13 1997-06-16 Sandoz Ltd Ophthalmic preparations containing cyclosporin
US5366739A (en) * 1992-08-06 1994-11-22 Deo Corporation Method of ophthalmic drug delivery
US5830508A (en) * 1992-08-06 1998-11-03 Deo Corporation Composition for treating dry eye
EP1142568A1 (en) 1992-09-25 2001-10-10 Novartis AG Pharmaceutical compositions containing cyclosporins
US5698533A (en) * 1994-07-26 1997-12-16 Kang; Meng-Che Ophthalmic pharmaceutical composition
EE03425B1 (en) 1994-11-03 2001-06-15 Arzneimittelwerk Dresden Gmbh Ciclosporin Preparations for Oral Administration with Simple Composition and High Bioavailability and Method of Preparation
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
NZ336900A (en) 1997-01-30 2001-06-29 Novartis Ag Hard gelatine capsules containing pharmaceutical compositions comprising cyclosporin A and being substantially free of any oil
US6254860B1 (en) * 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
US7557082B2 (en) 2006-03-03 2009-07-07 Allergan, Inc. Treatment with cyclosporin A
EP2214644B1 (en) * 2007-11-05 2013-03-20 Bausch & Lomb Incorporated Water-immiscible materials as vehicles for drug delivery
HUE034213T2 (en) * 2009-06-05 2018-01-29 Allergan Inc Easy and therapeutic use
KR102487299B1 (en) 2014-11-25 2023-01-10 알러간, 인코포레이티드 Stabilized omega-3 ophthalmic compositions
PT3399962T (en) 2016-12-23 2020-09-03 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
WO2021044045A1 (en) * 2019-09-06 2021-03-11 Novaliq Gmbh Ophthalmic composition for the treatment of uveitis
EP4201398A1 (en) * 2021-12-24 2023-06-28 Isoxa S.r.l. Isocyclosporin a for topical treatment of ocular diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649047A (en) * 1985-03-19 1987-03-10 University Of Georgia Research Foundation, Inc. Ophthalmic treatment by topical administration of cyclosporin
US4839342A (en) * 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin

Also Published As

Publication number Publication date
NL8902657A (en) 1990-05-16
KR900005973A (en) 1990-05-07
NO894266L (en) 1990-04-27
DE3935517A1 (en) 1990-05-03
BE1003578A4 (en) 1992-04-28
PT92120A (en) 1990-04-30
SE8903583D0 (en) 1989-10-26
DK531289D0 (en) 1989-10-25
AU4371589A (en) 1990-05-03
HU203046B (en) 1991-05-28
SE8903583L (en) 1990-04-27
FI895064A7 (en) 1990-04-27
CH679210A5 (en) 1992-01-15
LU87613A1 (en) 1991-05-07
FI895064A0 (en) 1989-10-25
JPH02164830A (en) 1990-06-25
ES2020032A6 (en) 1991-07-16
HUT52394A (en) 1990-07-28
FR2638089A1 (en) 1990-04-27
NZ231131A (en) 1992-06-25
GR890100690A (en) 1990-11-29
IL92120A0 (en) 1990-07-12
DK531289A (en) 1990-04-27
HU895444D0 (en) 1990-01-28
AU626928B2 (en) 1992-08-13
ZA898140B (en) 1991-06-26
GB2224205A (en) 1990-05-02
NO894266D0 (en) 1989-10-26
MY106271A (en) 1995-04-29
CA2001502A1 (en) 1990-04-26
PT92120B (en) 1995-06-30
GB2224205B (en) 1992-04-15
IL92120A (en) 1994-02-27
GB8924040D0 (en) 1989-12-13

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