GB824458A - Process for the production of tertiary thiophenylpyridylamines on their acid addition salts - Google Patents
Process for the production of tertiary thiophenylpyridylamines on their acid addition saltsInfo
- Publication number
- GB824458A GB824458A GB27004/57A GB2700457A GB824458A GB 824458 A GB824458 A GB 824458A GB 27004/57 A GB27004/57 A GB 27004/57A GB 2700457 A GB2700457 A GB 2700457A GB 824458 A GB824458 A GB 824458A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid addition
- addition salts
- thiophenylpyridylamines
- tertiary
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- -1 dimethylaminoethyl- Chemical group 0.000 abstract 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- NFJKVZHWAMBCRA-UHFFFAOYSA-N N-(2-piperidin-1-ylethyl)-N-thiophen-2-ylpyridin-2-amine Chemical class N1(CCCCC1)CCN(C1=NC=CC=C1)C=1SC=CC1 NFJKVZHWAMBCRA-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- IJCVBMSXIPFVLH-UHFFFAOYSA-N [C].S=O Chemical compound [C].S=O IJCVBMSXIPFVLH-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
In a process for the preparation of compounds of the general formula <FORM:0824458/IV (b)/1> or acid addition salts thereof, wherein Alk is a straight or branched alkylene chain, R1 and R2 are alkyl radicals, which may be linked to form a ring, which ring may also contain a further hetero atom, or R1 and/or R2, together with the nitrogen atom and the radical Alk may form a heterocyclic ring system, compounds of the general formula <FORM:0824458/IV (b)/2> wherein X is oxygen or sulphur are heated to an elevated temperature, preferably 150-250 DEG C., carbon dioxide or carbon oxysulphide being split off, and, if desired, the product is converted into an acid addition salt. Examples describe the preparation of dimethylaminoethyl-, diethylaminoisopropyl-, diethylaminoethyl-, and piperidinoethylthiophenylpyridylamines and their hydrochlorides. Specification 817,558 also is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE824458X | 1956-09-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB824458A true GB824458A (en) | 1959-12-02 |
Family
ID=6747285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27004/57A Expired GB824458A (en) | 1956-09-06 | 1957-08-27 | Process for the production of tertiary thiophenylpyridylamines on their acid addition salts |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB824458A (en) |
-
1957
- 1957-08-27 GB GB27004/57A patent/GB824458A/en not_active Expired
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