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GB2559216B - An electrowetting on dielectric droplet manipulation device - Google Patents

An electrowetting on dielectric droplet manipulation device

Info

Publication number
GB2559216B
GB2559216B GB1711420.8A GB201711420A GB2559216B GB 2559216 B GB2559216 B GB 2559216B GB 201711420 A GB201711420 A GB 201711420A GB 2559216 B GB2559216 B GB 2559216B
Authority
GB
United Kingdom
Prior art keywords
electrowetting
manipulation device
droplet manipulation
dielectric droplet
dielectric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1711420.8A
Other versions
GB201711420D0 (en
GB2559216A (en
Inventor
Ma Hanbin
Nathan Arokia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acxel Tech Ltd
Original Assignee
Acxel Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acxel Tech Ltd filed Critical Acxel Tech Ltd
Priority to GB1711420.8A priority Critical patent/GB2559216B/en
Publication of GB201711420D0 publication Critical patent/GB201711420D0/en
Priority to GB1810375.4A priority patent/GB2560679B/en
Priority to PCT/GB2018/051834 priority patent/WO2019016506A1/en
Priority to CN201880002445.XA priority patent/CN109475871B/en
Priority to KR1020207003455A priority patent/KR102224545B1/en
Publication of GB2559216A publication Critical patent/GB2559216A/en
Application granted granted Critical
Publication of GB2559216B publication Critical patent/GB2559216B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
GB1711420.8A 2017-07-17 2017-07-17 An electrowetting on dielectric droplet manipulation device Active GB2559216B (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB1711420.8A GB2559216B (en) 2017-07-17 2017-07-17 An electrowetting on dielectric droplet manipulation device
GB1810375.4A GB2560679B (en) 2017-07-17 2018-06-25 Method of controlling a tessellated array of electrodes
PCT/GB2018/051834 WO2019016506A1 (en) 2017-07-17 2018-06-29 Droplet manipulation
CN201880002445.XA CN109475871B (en) 2017-07-17 2018-06-29 Droplet manipulation
KR1020207003455A KR102224545B1 (en) 2017-07-17 2018-06-29 Electrowetting dielectric droplet drive device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1711420.8A GB2559216B (en) 2017-07-17 2017-07-17 An electrowetting on dielectric droplet manipulation device

Publications (3)

Publication Number Publication Date
GB201711420D0 GB201711420D0 (en) 2017-08-30
GB2559216A GB2559216A (en) 2018-08-01
GB2559216B true GB2559216B (en) 2019-02-06

Family

ID=59713472

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1711420.8A Active GB2559216B (en) 2017-07-17 2017-07-17 An electrowetting on dielectric droplet manipulation device
GB1810375.4A Active GB2560679B (en) 2017-07-17 2018-06-25 Method of controlling a tessellated array of electrodes

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1810375.4A Active GB2560679B (en) 2017-07-17 2018-06-25 Method of controlling a tessellated array of electrodes

Country Status (4)

Country Link
KR (1) KR102224545B1 (en)
CN (1) CN109475871B (en)
GB (2) GB2559216B (en)
WO (1) WO2019016506A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11353759B2 (en) * 2018-09-17 2022-06-07 Nuclera Nucleics Ltd. Backplanes with hexagonal and triangular electrodes
CN110694701B (en) * 2019-10-14 2021-12-07 中国科学院微电子研究所 Method and device for transporting liquid drops and method for cleaning liquid drop transport path
CN113203607A (en) * 2020-01-15 2021-08-03 佛山奥素博新科技有限公司 Preparation of samples on electrowetting-on-dielectric devices
CN113203676B (en) * 2020-01-15 2025-09-23 佛山奥素博新科技有限公司 Splitting droplets on electrowetting devices on dielectrics
US11596946B2 (en) * 2020-04-27 2023-03-07 Nuclera Nucleics Ltd. Segmented top plate for variable driving and short protection for digital microfluidics
US20240042436A1 (en) * 2020-12-24 2024-02-08 Foshan Acxel Boxin Tech Co., Ltd Micro-droplet generation method and generation system
CN114653410B (en) * 2020-12-24 2023-07-14 广东奥素液芯微纳科技有限公司 Micro-droplet generation method and system
CN114054108A (en) * 2021-11-05 2022-02-18 佛山奥素博新科技有限公司 Method for quickly generating micro-droplets
CN116393068A (en) * 2021-12-28 2023-07-07 彩科(苏州)生物科技有限公司 Optical tweezers and microfluidic devices based on oblique equi-density arrangement of phototransistors
CN118995406A (en) * 2024-08-05 2024-11-22 道简(深圳)医疗科技有限公司 Liquid preparation control system, method and automatic liquid preparation system

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040055891A1 (en) * 2002-09-24 2004-03-25 Pamula Vamsee K. Methods and apparatus for manipulating droplets by electrowetting-based techniques
WO2008091848A2 (en) * 2007-01-22 2008-07-31 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
US20110220505A1 (en) * 2010-03-09 2011-09-15 Sparkle Power Inc. Droplet manipulations on ewod microelectrode array architecture
EP2756885A2 (en) * 2013-01-16 2014-07-23 Sharp Kabushiki Kaisha Efficient dilution method, including washing method for immunoassay
CN105665043A (en) * 2016-01-29 2016-06-15 复旦大学 EWOD (electrowetting on dielectric)-based two-dimensional digital micro-fluidic chip provided with honeycomb electrode array
WO2016166944A1 (en) * 2015-04-15 2016-10-20 Sharp Kabushiki Kaisha An electrowetting on dielectric (ewod) device and a method of controlling an ewod device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008072166A1 (en) * 2006-12-12 2008-06-19 Koninklijke Philips Electronics N.V. Method and apparatus for cell analysis
CN100495186C (en) * 2007-12-21 2009-06-03 北京派瑞根科技开发有限公司 Electronic printing apparatus and electronic paper printing method
TW201227454A (en) * 2010-12-31 2012-07-01 Hong-Da Liu An active array having the touchable sensing matrix unit and a display having the active array
CN102671723B (en) * 2011-02-17 2015-03-11 王崇智 Method of manipulating droplet on ewod microelectrode array architecture
EP3848091A1 (en) 2011-03-07 2021-07-14 The Trustees of Columbia University in the City of New York Apparatus, method, and system for selectively effecting and/or killing bacteria
US8981789B2 (en) * 2012-04-16 2015-03-17 Sharp Kabushiki Kaisha Active matrix device and method of driving the same
WO2014135232A1 (en) * 2013-03-04 2014-09-12 Tecan Trading Ag Manipulating the size of liquid droplets in digital microfluidics
GB2533952A (en) * 2015-01-08 2016-07-13 Sharp Kk Active matrix device and method of driving
JP2017045385A (en) 2015-08-28 2017-03-02 株式会社デンソー Drive assist apparatus and program
JP6561881B2 (en) 2016-03-15 2019-08-21 ウシオ電機株式会社 UV radiation device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040055891A1 (en) * 2002-09-24 2004-03-25 Pamula Vamsee K. Methods and apparatus for manipulating droplets by electrowetting-based techniques
WO2008091848A2 (en) * 2007-01-22 2008-07-31 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
US20110220505A1 (en) * 2010-03-09 2011-09-15 Sparkle Power Inc. Droplet manipulations on ewod microelectrode array architecture
EP2756885A2 (en) * 2013-01-16 2014-07-23 Sharp Kabushiki Kaisha Efficient dilution method, including washing method for immunoassay
WO2016166944A1 (en) * 2015-04-15 2016-10-20 Sharp Kabushiki Kaisha An electrowetting on dielectric (ewod) device and a method of controlling an ewod device
CN105665043A (en) * 2016-01-29 2016-06-15 复旦大学 EWOD (electrowetting on dielectric)-based two-dimensional digital micro-fluidic chip provided with honeycomb electrode array

Also Published As

Publication number Publication date
GB2560679B (en) 2019-09-18
CN109475871A (en) 2019-03-15
CN109475871B (en) 2021-11-09
KR102224545B1 (en) 2021-03-08
KR20200018704A (en) 2020-02-19
GB201711420D0 (en) 2017-08-30
GB201810375D0 (en) 2018-08-08
GB2560679A (en) 2018-09-19
WO2019016506A1 (en) 2019-01-24
GB2559216A (en) 2018-08-01

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

Free format text: REGISTERED BETWEEN 20210812 AND 20210818

PCNP Patent ceased through non-payment of renewal fee

Effective date: 20210717

S28 Restoration of ceased patents (sect. 28/pat. act 1977)

Free format text: APPLICATION FILED

S28 Restoration of ceased patents (sect. 28/pat. act 1977)

Free format text: RESTORATION ALLOWED

Effective date: 20220922