GB2354518B - A porous ceramic body composed of bonded particles - Google Patents
A porous ceramic body composed of bonded particlesInfo
- Publication number
- GB2354518B GB2354518B GB0100084A GB0100084A GB2354518B GB 2354518 B GB2354518 B GB 2354518B GB 0100084 A GB0100084 A GB 0100084A GB 0100084 A GB0100084 A GB 0100084A GB 2354518 B GB2354518 B GB 2354518B
- Authority
- GB
- United Kingdom
- Prior art keywords
- particles
- bonded
- article
- dispersion
- remove
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 239000000919 ceramic Substances 0.000 title abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 239000006185 dispersion Substances 0.000 abstract 2
- 239000007789 gas Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000011148 porous material Substances 0.000 abstract 2
- 238000013019 agitation Methods 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 210000002449 bone cell Anatomy 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000010304 firing Methods 0.000 abstract 1
- 239000006260 foam Substances 0.000 abstract 1
- 238000005187 foaming Methods 0.000 abstract 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B38/00—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof
- C04B38/0038—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof by superficial sintering or bonding of particulate matter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B38/00—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof
- C04B38/06—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof by burning-out added substances by burning natural expanding materials or by sublimating or melting out added substances
- C04B38/0615—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof by burning-out added substances by burning natural expanding materials or by sublimating or melting out added substances the burned-out substance being a monolitic element having approximately the same dimensions as the final article, e.g. a porous polyurethane sheet or a prepreg obtained by bonding together resin particles
- C04B38/062—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof by burning-out added substances by burning natural expanding materials or by sublimating or melting out added substances the burned-out substance being a monolitic element having approximately the same dimensions as the final article, e.g. a porous polyurethane sheet or a prepreg obtained by bonding together resin particles the burned-out substance being formed in situ, e.g. by polymerisation of a prepolymer composition containing ceramic powder
- C04B38/0625—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof by burning-out added substances by burning natural expanding materials or by sublimating or melting out added substances the burned-out substance being a monolitic element having approximately the same dimensions as the final article, e.g. a porous polyurethane sheet or a prepreg obtained by bonding together resin particles the burned-out substance being formed in situ, e.g. by polymerisation of a prepolymer composition containing ceramic powder involving a foaming step of the burnable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
- C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
- C04B2111/00836—Uses not provided for elsewhere in C04B2111/00 for medical or dental applications
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Ceramic Engineering (AREA)
- Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Structural Engineering (AREA)
- Organic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Porous Artificial Stone Or Porous Ceramic Products (AREA)
Abstract
A method of making a porous article composed of bonded particles and having a controlled level of porosity, pore size and interconnectivity comprises the steps of: <SL> <LI>a) forming a dispersion comprising a liquid carrier, the particles to be bonded and a polymerisable monomeric material; <LI>b) introducing small bubbles of oxygen containing gas into the dispersion with agitation to form a foam which is allowed to caused to coalesce; <LI>c) adjusting the concentration of oxygen within the foaming gas to control the onset of polymerisation, then <LI>d) polymerising the foamed structure; <LI>e) drying the structure to remove the liquid carrier and provide a solid article having pores derived from the bubbles, and <LI>f) firing the article to remove the organic binder and provide a ceramic bond. </SL> The particles may be of hydroxyapatite, which gives a product used in bone cell culture, or for carrying drugs.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0100084A GB2354518B (en) | 1996-10-04 | 1996-10-04 | A porous ceramic body composed of bonded particles |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0100084A GB2354518B (en) | 1996-10-04 | 1996-10-04 | A porous ceramic body composed of bonded particles |
| GB9620752A GB2317887A (en) | 1996-10-04 | 1996-10-04 | Porous ceramic articles; bone cell growth and drug carriers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB0100084D0 GB0100084D0 (en) | 2001-02-14 |
| GB2354518A GB2354518A (en) | 2001-03-28 |
| GB2354518B true GB2354518B (en) | 2001-06-13 |
Family
ID=10800966
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0100085A Expired - Lifetime GB2354519B (en) | 1996-10-04 | 1996-10-04 | Production of porous ceramic articles |
| GB9620752A Withdrawn GB2317887A (en) | 1996-10-04 | 1996-10-04 | Porous ceramic articles; bone cell growth and drug carriers |
| GB0100084A Expired - Lifetime GB2354518B (en) | 1996-10-04 | 1996-10-04 | A porous ceramic body composed of bonded particles |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0100085A Expired - Lifetime GB2354519B (en) | 1996-10-04 | 1996-10-04 | Production of porous ceramic articles |
| GB9620752A Withdrawn GB2317887A (en) | 1996-10-04 | 1996-10-04 | Porous ceramic articles; bone cell growth and drug carriers |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0958261A1 (en) |
| JP (1) | JP2001501902A (en) |
| AU (1) | AU4563997A (en) |
| GB (3) | GB2354519B (en) |
| WO (1) | WO1998015505A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8173149B2 (en) | 2001-03-02 | 2012-05-08 | Stryker Corporation | Method for producing porous β-tricalcium phosphate granules |
| US8765189B2 (en) | 2011-05-13 | 2014-07-01 | Howmedica Osteonic Corp. | Organophosphorous and multivalent metal compound compositions and methods |
| US9265857B2 (en) | 2010-05-11 | 2016-02-23 | Howmedica Osteonics Corp. | Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19718672C1 (en) * | 1997-05-02 | 1998-09-24 | Zschimmer & Schwarz Gmbh & Co | Use of a sugar |
| GB9821663D0 (en) | 1998-10-05 | 1998-11-25 | Abonetics Ltd | Foamed ceramics |
| GB9825109D0 (en) * | 1998-11-16 | 1999-01-13 | Dytech Corp Ltd | Porous ceramic matrices |
| JP3400740B2 (en) | 1999-04-13 | 2003-04-28 | 東芝セラミックス株式会社 | Calcium phosphate porous sintered body and method for producing the same |
| JP2002543930A (en) * | 1999-05-12 | 2002-12-24 | デー アンド イー クライオー シーシー | Ceramic wound treatment device |
| EP1108698B8 (en) * | 1999-12-16 | 2006-10-04 | IsoTis N.V. | Porous ceramic body |
| AU778651B2 (en) | 1999-12-16 | 2004-12-16 | Isotis N.V. | Porous ceramic body |
| US20020022885A1 (en) * | 2000-05-19 | 2002-02-21 | Takahiro Ochi | Biomaterial |
| GB0019003D0 (en) * | 2000-08-04 | 2000-09-20 | Lo Wei Jen | Porous synthetic bone graft and method of manufacture thereof |
| GB0020610D0 (en) * | 2000-08-21 | 2000-10-11 | Dytech Corp Ltd | Uses of porous carriers |
| GB0020734D0 (en) * | 2000-08-22 | 2000-10-11 | Dytech Corp Ltd | Bicontinuous composites |
| US6713420B2 (en) | 2000-10-13 | 2004-03-30 | Toshiba Ceramics Co., Ltd. | Porous ceramics body for in vivo or in vitro use |
| JP4070951B2 (en) | 2000-12-07 | 2008-04-02 | ペンタックス株式会社 | Method for producing porous calcium phosphate ceramic sintered body |
| WO2002049978A1 (en) | 2000-12-21 | 2002-06-27 | Corning Incorporated | Refractories for fused silica production furnaces |
| DE10113108B4 (en) * | 2001-03-15 | 2007-07-26 | Dot Gmbh | Active substance-containing calcium phosphate materials |
| EP1293220B1 (en) | 2001-09-13 | 2006-11-08 | Akira Myoi | Porous calcium phosphate ceramics for in vivo use |
| US20060135340A1 (en) * | 2002-07-30 | 2006-06-22 | Cheang Hong N P | Spherical nano-composite powder and a method of preparing the same |
| DE10328892A1 (en) | 2003-06-26 | 2005-05-12 | Curasan Ag | Bone building agent and manufacturing process |
| JP4215595B2 (en) * | 2003-08-21 | 2009-01-28 | 安正 赤川 | Implant fixing member and implant composite material |
| WO2007086964A2 (en) | 2005-10-21 | 2007-08-02 | University Of South Florida | Method of producing interconnected volumetric porosity in materials |
| CA2695946C (en) * | 2007-08-09 | 2017-06-13 | The Board Of Regents Of The University Of Texas System | Bi-layered bone-like scaffolds |
| US8044105B2 (en) | 2008-02-04 | 2011-10-25 | Dow Global Technologies Llc | Water-based ceramic foams showing improved gel strength |
| CN109512678B (en) * | 2018-11-28 | 2022-04-08 | 福建工程学院 | A kind of preparation method of denture membrane |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2078696A (en) * | 1980-05-28 | 1982-01-13 | Mitsubishi Mining & Cement Co | Porous Calcium Phosphate Body |
| GB2142919A (en) * | 1983-07-09 | 1985-01-30 | Sumitomo Cement Co | Porous ceramic material and processes for preparing same |
| US4629464A (en) * | 1984-09-25 | 1986-12-16 | Tdk Corporation | Porous hydroxyapatite material for artificial bone substitute |
| US4846838A (en) * | 1983-07-15 | 1989-07-11 | Tdk Corporation | Prosthetic body for bone substitute and a method for the preparation thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3537947A (en) * | 1967-05-18 | 1970-11-03 | Uniroyal Inc | Leather-like poromeric material and method for making the same |
| US4218255A (en) * | 1976-08-30 | 1980-08-19 | University Of Dayton | Porous ceramic carriers for controlled release of proteins, polypeptide hormones, and other substances within human and/or other mamillian species and method |
| JPS56145153A (en) * | 1980-03-05 | 1981-11-11 | Toyo Tire & Rubber Co | Manufacture of porous ceramic moldings |
| DK154260C (en) * | 1981-02-20 | 1989-05-22 | Mundipharma Gmbh | PROCEDURE FOR THE MANUFACTURING OF A BONE IMPLANT OF FURNISHED TRICAL CUMPHOSPHATE, SPECIFICALLY FOR FILLING OF SPACES OR FOR COMPOSITION OF BONE PARTS AFTER FRACTURE. |
| US5011495A (en) * | 1990-02-16 | 1991-04-30 | The United States Of America As Represented By The Secretary Of The Army | Unique bone regeneration tricalcium phosphate |
| JP3417943B2 (en) * | 1991-08-12 | 2003-06-16 | ダイテック コーポレイション リミテッド | Porous body |
| DE4313715A1 (en) * | 1993-04-27 | 1994-11-03 | Roehm Gmbh | Highly filled, foamed polymer material |
| GB9409258D0 (en) * | 1994-05-10 | 1994-06-29 | Dytech Corp Ltd | Production of ceramic articles |
| GB2289466B (en) * | 1994-05-10 | 1997-10-22 | Dytech Corp Ltd | Production of porous refractory articles |
-
1996
- 1996-10-04 GB GB0100085A patent/GB2354519B/en not_active Expired - Lifetime
- 1996-10-04 GB GB9620752A patent/GB2317887A/en not_active Withdrawn
- 1996-10-04 GB GB0100084A patent/GB2354518B/en not_active Expired - Lifetime
-
1997
- 1997-10-01 EP EP97943989A patent/EP0958261A1/en not_active Withdrawn
- 1997-10-01 AU AU45639/97A patent/AU4563997A/en not_active Abandoned
- 1997-10-01 JP JP10517285A patent/JP2001501902A/en not_active Ceased
- 1997-10-01 WO PCT/GB1997/002705 patent/WO1998015505A1/en not_active Ceased
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2078696A (en) * | 1980-05-28 | 1982-01-13 | Mitsubishi Mining & Cement Co | Porous Calcium Phosphate Body |
| GB2142919A (en) * | 1983-07-09 | 1985-01-30 | Sumitomo Cement Co | Porous ceramic material and processes for preparing same |
| US4846838A (en) * | 1983-07-15 | 1989-07-11 | Tdk Corporation | Prosthetic body for bone substitute and a method for the preparation thereof |
| US4629464A (en) * | 1984-09-25 | 1986-12-16 | Tdk Corporation | Porous hydroxyapatite material for artificial bone substitute |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8173149B2 (en) | 2001-03-02 | 2012-05-08 | Stryker Corporation | Method for producing porous β-tricalcium phosphate granules |
| US9265857B2 (en) | 2010-05-11 | 2016-02-23 | Howmedica Osteonics Corp. | Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods |
| US8765189B2 (en) | 2011-05-13 | 2014-07-01 | Howmedica Osteonic Corp. | Organophosphorous and multivalent metal compound compositions and methods |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2354519A8 (en) | 2001-07-19 |
| GB9620752D0 (en) | 1996-11-20 |
| GB2317887A (en) | 1998-04-08 |
| GB0100085D0 (en) | 2001-02-14 |
| GB2354519A (en) | 2001-03-28 |
| GB0100084D0 (en) | 2001-02-14 |
| JP2001501902A (en) | 2001-02-13 |
| AU4563997A (en) | 1998-05-05 |
| WO1998015505A1 (en) | 1998-04-16 |
| GB2354518A (en) | 2001-03-28 |
| EP0958261A1 (en) | 1999-11-24 |
| GB2354519B (en) | 2001-06-13 |
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