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GB2199325B - Process for preparing 16-dehydro-20-oxopregnane derivatives and such derivatives - Google Patents

Process for preparing 16-dehydro-20-oxopregnane derivatives and such derivatives

Info

Publication number
GB2199325B
GB2199325B GB8730269A GB8730269A GB2199325B GB 2199325 B GB2199325 B GB 2199325B GB 8730269 A GB8730269 A GB 8730269A GB 8730269 A GB8730269 A GB 8730269A GB 2199325 B GB2199325 B GB 2199325B
Authority
GB
United Kingdom
Prior art keywords
derivatives
dehydro
preparing
oxopregnane
oxopregnane derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8730269A
Other versions
GB2199325A (en
GB8730269D0 (en
Inventor
Andras Toro
Gabor Ambrus
Nandor Makk
Tibor Lang
Eva Ilkoy
Lajos Toldy
Antonia Jekkel
Sarudy Eva Toth
Gyula Horvath
Karoly Albrecht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of GB8730269D0 publication Critical patent/GB8730269D0/en
Publication of GB2199325A publication Critical patent/GB2199325A/en
Application granted granted Critical
Publication of GB2199325B publication Critical patent/GB2199325B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GB8730269A 1986-12-29 1987-12-29 Process for preparing 16-dehydro-20-oxopregnane derivatives and such derivatives Expired - Lifetime GB2199325B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU549986A HU198736B (en) 1986-12-29 1986-12-29 Process for producing 16-dehydro-20-oxopregnane derivatives

Publications (3)

Publication Number Publication Date
GB8730269D0 GB8730269D0 (en) 1988-02-03
GB2199325A GB2199325A (en) 1988-07-06
GB2199325B true GB2199325B (en) 1990-04-25

Family

ID=10970368

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8730269A Expired - Lifetime GB2199325B (en) 1986-12-29 1987-12-29 Process for preparing 16-dehydro-20-oxopregnane derivatives and such derivatives

Country Status (4)

Country Link
JP (1) JPH0830076B2 (en)
GB (1) GB2199325B (en)
HU (1) HU198736B (en)
NL (1) NL8703151A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2720747B1 (en) * 1994-06-02 1996-07-12 Roussel Uclaf New process for the preparation of a 16-beta-methyl steroid and new intermediates.
JP4827189B2 (en) 2004-05-14 2011-11-30 塩野義製薬株式会社 Oxidation of alcohols using hydrogen peroxide and tungsten catalysts
CN1907998B (en) * 2005-08-05 2010-05-26 天津天药药业股份有限公司 Refining process of intermediate 21-methyltetraene of dexamethasone series products
CN105622700B (en) * 2016-01-29 2017-12-22 山东赛托生物科技股份有限公司 A kind of synthetic method of steroidal intermediate 5ST

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2966511D1 (en) * 1978-07-31 1984-02-02 Upjohn Co Epoxypregnadienes, hydroxypregnatrienes, process for their preparation and process for their conversion to precursors of useful anti-inflammatory agents
US4189430A (en) * 1978-07-31 1980-02-19 The Upjohn Company Epoxide process

Also Published As

Publication number Publication date
HU198736B (en) 1989-11-28
JPS63190898A (en) 1988-08-08
GB2199325A (en) 1988-07-06
NL8703151A (en) 1988-07-18
HUT46035A (en) 1988-09-28
GB8730269D0 (en) 1988-02-03
JPH0830076B2 (en) 1996-03-27

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19961229