GB2144991A - Hair growth promotor - Google Patents
Hair growth promotor Download PDFInfo
- Publication number
- GB2144991A GB2144991A GB08419228A GB8419228A GB2144991A GB 2144991 A GB2144991 A GB 2144991A GB 08419228 A GB08419228 A GB 08419228A GB 8419228 A GB8419228 A GB 8419228A GB 2144991 A GB2144991 A GB 2144991A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hair
- vitamin
- adrenal
- oestrogens
- generating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003779 hair growth Effects 0.000 title abstract description 3
- 230000001919 adrenal effect Effects 0.000 claims abstract description 20
- 239000005556 hormone Substances 0.000 claims abstract description 19
- 229940088597 hormone Drugs 0.000 claims abstract description 19
- 239000000262 estrogen Substances 0.000 claims abstract description 18
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims abstract description 12
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims abstract description 12
- 229930003471 Vitamin B2 Natural products 0.000 claims abstract description 12
- 229960002477 riboflavin Drugs 0.000 claims abstract description 12
- 235000019164 vitamin B2 Nutrition 0.000 claims abstract description 12
- 239000011716 vitamin B2 Substances 0.000 claims abstract description 12
- 239000003795 chemical substances by application Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000003860 topical agent Substances 0.000 claims description 2
- 239000002075 main ingredient Substances 0.000 abstract description 8
- 230000000699 topical effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 10
- 239000007788 liquid Substances 0.000 description 10
- 239000004615 ingredient Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 2
- FPXKNYVSOKOLKD-BTJKTKAUSA-N (z)-but-2-enedioic acid;n-chloroaniline Chemical compound OC(=O)\C=C/C(O)=O.ClNC1=CC=CC=C1 FPXKNYVSOKOLKD-BTJKTKAUSA-N 0.000 description 2
- UYIFTLBWAOGQBI-BZDYCCQFSA-N Benzhormovarine Chemical compound C([C@@H]1[C@@H](C2=CC=3)CC[C@]4([C@H]1CC[C@@H]4O)C)CC2=CC=3OC(=O)C1=CC=CC=C1 UYIFTLBWAOGQBI-BZDYCCQFSA-N 0.000 description 2
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 2
- 239000004470 DL Methionine Substances 0.000 description 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 2
- LRJOMUJRLNCICJ-JZYPGELDSA-N Prednisolone acetate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O LRJOMUJRLNCICJ-JZYPGELDSA-N 0.000 description 2
- 229930003756 Vitamin B7 Natural products 0.000 description 2
- 229930003427 Vitamin E Natural products 0.000 description 2
- 235000019441 ethanol Nutrition 0.000 description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 2
- 229940041616 menthol Drugs 0.000 description 2
- FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 description 2
- 229930182817 methionine Natural products 0.000 description 2
- 235000006109 methionine Nutrition 0.000 description 2
- 229960002800 prednisolone acetate Drugs 0.000 description 2
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 description 2
- 239000011764 pyridoxine hydrochloride Substances 0.000 description 2
- 229960004172 pyridoxine hydrochloride Drugs 0.000 description 2
- 235000011912 vitamin B7 Nutrition 0.000 description 2
- 239000011735 vitamin B7 Substances 0.000 description 2
- 235000019165 vitamin E Nutrition 0.000 description 2
- 239000011709 vitamin E Substances 0.000 description 2
- 229940046009 vitamin E Drugs 0.000 description 2
- 201000004384 Alopecia Diseases 0.000 description 1
- ITRJWOMZKQRYTA-RFZYENFJSA-N Cortisone acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)CC2=O ITRJWOMZKQRYTA-RFZYENFJSA-N 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- VWWQXMAJTJZDQX-UHFFFAOYSA-N Flavine adenine dinucleotide Natural products C1=NC2=C(N)N=CN=C2N1C(C(O)C1O)OC1COP(O)(=O)OP(O)(=O)OCC(O)C(O)C(O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UHFFFAOYSA-N 0.000 description 1
- 241000872198 Serjania polyphylla Species 0.000 description 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
- LXNHXLLTXMVWPM-UHFFFAOYSA-N Vitamin B6 Natural products CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 1
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 239000003098 androgen Substances 0.000 description 1
- 229940030486 androgens Drugs 0.000 description 1
- 230000001387 anti-histamine Effects 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 229960003290 cortisone acetate Drugs 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- VWWQXMAJTJZDQX-UYBVJOGSSA-N flavin adenine dinucleotide Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UYBVJOGSSA-N 0.000 description 1
- FVTCRASFADXXNN-SCRDCRAPSA-N flavin mononucleotide Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O FVTCRASFADXXNN-SCRDCRAPSA-N 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229960003966 nicotinamide Drugs 0.000 description 1
- 235000005152 nicotinamide Nutrition 0.000 description 1
- 239000011570 nicotinamide Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A topical hair growth preparation involving oestrogens, adrenal homones and vitamin B2 as main ingredients with low concentration and specified ratio of oestrogen to adrenal hormone.
Description
SPECIFICATION
Agent for generating the hair
BACKGROUND OF THE INVENTION
Generally, there are many examples in which the ingredients of agents promoted for curing baldness or generating the hair are oestrogens and adrenal hormones. It has been widely believed that the reason why there are many bald-headed men but few or no bald-headed women is that men tend to have excessive androgens; however, no woman has such a tendency. It is thus clear why there are many examples in which oestrogens are proposed in agents to cure lack of hair, aiming to supplement natural oestrogens in cutaneous organization.
Agents containing oestrogens, with vitamin
E or H, alcohol, menthol, etc., as their main ingredients, or those adding vitamin E or H, alcohol, menthol, etc. to adrenal hormones have been known. It is however a fact that these agents have no effect in generating the hair, without exception, yet recognising this fact, people use such ineffective agents with some expectation. Many examples have been found in which inflammations have occurred in the skin as well as failure to show hair growth, or even to cause loss of existing hair.
The inventor has made repeated researches in connection with the status of agents for generating the hair sold in the market as mentioned above, and the use of oestrogens and adrenal hormones certainly has a reasonability from the point of view of their characteristics. However, it was plain to the inventor that many matters remained to be researched for the conditions of use to be elucidated.
Adrenal hormones of a concentration of 0.5 per cent are for example used for circular epilation, but there is a problem of concentration for long term use. The inventor however has tested possibilities in a low concentration range that is not conventionally thought valuable. There is no example in-which oestrogens and adrenal hormones are used together, but the inventor has found the possibility of using them in a specific range of mixing ratios.
There have been some examples of using vitamins as promoting agent for metabolism of proteins, but it is important to search for a combination to demonstrate a precise and strong promoting action in the present context.
THE INVENTION
The present invention has been completed as the result of investigations based on the ideas stated above, and provides an agent for generating the hair efficiently by applying it to the human head, without adverse side effects.
Thus there is provided a topical agent that comprises oestrogen 0.0033 to 1.0 mg%(i.e.
mg per 100 cc), adrenal hormone 0.018 to 2.75 mg%, and vitamin B2 from 0.085 up to 25.5 mg% as main ingredients thereof, conveniently dissolved in distilled water as a medium, with an oestrogen/adrenal hormone weight ratio of 0.01 to 4.0.
The following examples illustrate the invention, without limitation.
Example 1.
Embodiment 1 of this invention is as follows: an agent containing oestradiol benzoate (oestrogen) 0.005 mg; prednisolone acetate (adrenal hormone) 0.0275 mg; riboflavine phosphate (vitamin B2) 0.125 mg, and flavine-adenine dinucleotide (vitamin B2) 0.0025 mg asmain ingredients as well as chlorophenylamine maleate (antihistamine) 0.075 mg; pyridoxine hydrochloride (vitamin B6) 0.25 mg; nicotinamide 0.5 mg; pantothenyl alcohol 0.25 mg; and DL-methionine 1.0 mg were uniformly dissolved in refined water 100 cc.
To make this preparation material in liquid form in injection ampoules was used for each of the materials and the purity thereof was essentially 100 per cent. For example, oestra diol benzoate 0.2 mg was in aqueous suspension 1 cc in an ampoule; this liquid was uniformly dissolved in refined water, 4 litres and since this preparation is of a low concentration, the material is perfectly dissolved.
Specific amounts of the other materials contained respectively in 2 cc ampoules were also dissolved uniformly in the said refined water.
Example 2.
Next, as embodiment 2 of this invention, cortisone acetate (adrenal hormone) 0.0275 mg was used instead of the prednisolone acetate in embodiment 1, and the other materials and their quantities were as above.
In use, the agents are applied to the bald areas. Embodiments 1 and 2 give the maximum efficiency among many embodiments tried by the applicant and having effects for yielding the hair. Embodiments 1 and 2 differ only in the kinds of their adrenal hormones, the other conditions being the same; however, the effects for generating the hair of both are the same.
As the result of tests, changing various conditions, the applicant has shown that oestrogens, adrenal hormones and vitamin B2 play the roles of the main ingredients, in the relative amounts already given. It has been recognized that an effect for yielding the hair appears only when the three ingredients of oestrogens, adrenal hormones and vitamin B2 are respectively in the ranges given and also the quantitative ratio of the oestrogens to the adrenal hormones is as given.
Under such conditions, an effect in generating the hair appears; the maximum effect in yielding hair is seen at the quantitative relationship among the three main ingredients given in embodiments 1 and 2 above.
It is further noted that no inflammation in the skin occurs, because the oestrogens and the adrenal hormones have been made as ultra-low concentrations. Also the liquid does not reach such a quantity as to cause inflammation and to prevent hair generation if it is absorbed and accumulated into the skin.
Thus an agent for yielding hair according to this invention gives a good effect for generating hair but causes no inflammation of the skin. it has been known that vitamin B2 has an action in promoting metabolism of proteins, however, no example using vitamin B2 for yielding hair has been found before. In this invention it has been recognized that vitamin B2 gives a remarkable efficiency for generating the hair as a main ingredient, in the three-ingredient system of oestrogens, adrenal hormones and vitamin B2 Each ingredient other than the main ingredients added in the specific embodiments differs from the main ingredients and shows a specific effect.It is found that chlorophenylamine maleate intensifies the action of adrenal hormones and that pyridoxine hydrochloride, nicotinamide, pantothenyl alcohol, and
DL-methionine have effects strengthening the action of vitamin B2 in the metabolism of proteins.
Examples of applying the agent are described below to show its efficiency.
Tests Applied:
The tests were carried out by applying the liquid described in embodiment 1 above, once or twice a day with a rate of use of the liquid approximately from 50 to 100 cc a month.
The liquid was applied to 60 persons; hair generation and change in white hair to black were found for all of them. With the young bald-headed, efficiency was recognized in three months, and in addition, hair generation was also found even for a man as old as 75 years. Other examples are given below:
(1) A man, 30 years old
The liquid, 300 cc, was used for three months, once or twice a day; a bald patch on the left side of the head as large as the palm of a human hand was restored perfectly with the hair given.
(2) A man, 43 years old
The liquid, 120 cc, was used for two months, once or twice a day; hair was completely- generated on a bald patch at the front of the head.
(3) A man, 30 years old
The liquid, 1 20 cc, was for two months, once a day; a bald patch on the top of the head was restored with the hair generated.
(4) A man, 60 years old
The liquid, 200 cc, was used for one and a half months, twice a day; his white and pale hair was changed to black with fresh growth.
Claims (2)
1. A topical agent for generating the hair, comprising oestrogen 0.0033 to 1.0 mg%.
adrenal hormone 0.018 to 2.75 mg% and vitamin B2 0.085 to 25.5 mg% the weight ratio of the oestrogen to the adrenal hormone being 0.01 to 4.0. in water or other medium.
2. An agent for generating the hair substantially as herein described in Example 1 or 2.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58145708A JPS6038313A (en) | 1983-08-11 | 1983-08-11 | Hair restorer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB8419228D0 GB8419228D0 (en) | 1984-08-30 |
| GB2144991A true GB2144991A (en) | 1985-03-20 |
| GB2144991B GB2144991B (en) | 1987-04-15 |
Family
ID=15391281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB08419228A Expired GB2144991B (en) | 1983-08-11 | 1984-07-27 | Hair growth promotor |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS6038313A (en) |
| KR (1) | KR860001587B1 (en) |
| CA (1) | CA1240618A (en) |
| DE (1) | DE3417136C2 (en) |
| FR (1) | FR2550448B1 (en) |
| GB (1) | GB2144991B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992012699A1 (en) * | 1991-01-15 | 1992-08-06 | Wolfgang Weuffen | Cosmetic or pharmaceutical compositions for improving hair quality and promoting hair growth |
| WO2000018362A1 (en) * | 1998-09-28 | 2000-04-06 | Petersen, Sharleen, Caron | Hair growth stimulant |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19509354A1 (en) * | 1994-12-08 | 1996-06-13 | Klett Loch Lore M | Combination preparation for promoting hair growth and possibly skin and nail growth and for preventing or eliminating hair loss |
| IT202300003327A1 (en) * | 2023-02-24 | 2024-08-24 | Giuliani Spa | COMPOSITION TO IMPROVE THE AESTHETIC APPEARANCE OF HAIR AND PROMOTE ITS GROWTH |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2257223A1 (en) * | 1972-11-22 | 1974-06-12 | Fouad Dr Med Talabani | Hair growth and anti- hairloss compsn. - contg. mixts of androgen, oestrogen, corticoid and carriers |
| JPS5879913A (en) * | 1981-11-09 | 1983-05-13 | Taizo Ayukawa | Hair tonic composition |
-
1983
- 1983-08-11 JP JP58145708A patent/JPS6038313A/en active Granted
-
1984
- 1984-05-09 DE DE3417136A patent/DE3417136C2/en not_active Expired
- 1984-05-31 KR KR1019840003033A patent/KR860001587B1/en not_active Expired
- 1984-06-19 FR FR8409594A patent/FR2550448B1/en not_active Expired
- 1984-07-18 CA CA000459176A patent/CA1240618A/en not_active Expired
- 1984-07-27 GB GB08419228A patent/GB2144991B/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992012699A1 (en) * | 1991-01-15 | 1992-08-06 | Wolfgang Weuffen | Cosmetic or pharmaceutical compositions for improving hair quality and promoting hair growth |
| US5629002A (en) * | 1991-01-15 | 1997-05-13 | Weuffen; Wolfgang | Cosmetic or pharmaceutic preparations for improving hair quaility and stimulating growth of the hair |
| WO2000018362A1 (en) * | 1998-09-28 | 2000-04-06 | Petersen, Sharleen, Caron | Hair growth stimulant |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1240618A (en) | 1988-08-16 |
| GB2144991B (en) | 1987-04-15 |
| FR2550448A1 (en) | 1985-02-15 |
| KR850002395A (en) | 1985-05-13 |
| JPS6038313A (en) | 1985-02-27 |
| JPH0441123B2 (en) | 1992-07-07 |
| GB8419228D0 (en) | 1984-08-30 |
| DE3417136C2 (en) | 1986-01-23 |
| DE3417136A1 (en) | 1985-02-21 |
| KR860001587B1 (en) | 1986-10-13 |
| FR2550448B1 (en) | 1987-04-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5990100A (en) | Composition and method for treatment of psoriasis | |
| US4826683A (en) | Decongestant | |
| US4545990A (en) | Anti-acne composition | |
| CA1187416A (en) | Hair tonic composition | |
| MXPA01011560A (en) | Topical compositions for prostaglandin e1. | |
| JPH02500976A (en) | anti-inflammatory cream composition | |
| WO1997003676A1 (en) | Novel pharmaceutical formulation of dehydroepiandrosterone for percutaneous topical application | |
| US4927631A (en) | Decongestant preparation | |
| EP0216303B1 (en) | External medication | |
| JP7802370B2 (en) | Hydroalcoholic gel and method for producing the gel | |
| FI962056A0 (en) | New pharmaceutical composition for the manufacture of stable powder containing as active ingredient a combination of acetylsalicylic acid and methoclopramide | |
| GB2144991A (en) | Hair growth promotor | |
| US5886038A (en) | Composition and method for treatment of psoriasis | |
| KR20020038595A (en) | Topical Formulations Comprising Skin Penetration Agents and the Use Thereof | |
| US3119739A (en) | Acetylmethyl-salicylate for pain relief | |
| EP0175701A1 (en) | Skin treatment compositions | |
| de Vlaming et al. | Pituitary, adrenal and thyroid influences on osmoregulation in the euryhaline elasmobranch, Dasyatis sabina | |
| Shafer et al. | Salivary Gland Function in the Rat: III. Protease and Arginase Activity of Submaxillary Glands and Whole Saliva | |
| GB2167957A (en) | Hair growth stimulating compositions | |
| US4863950A (en) | Medicinal formulation for promoting keratinogenesis and reducing seborrhea of the face and scalp | |
| RU2021805C1 (en) | Foam-washing agent for individual hygiene | |
| JPS6038315A (en) | Hair tonic composition | |
| JPS6361287B2 (en) | ||
| RU2025119C1 (en) | Agent for hair washing | |
| Schweizer et al. | Effects of Adrenal and Thyroid Hormones on Water Exchange in Hypophysectomized Rats. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |