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GB2016687A - Sugar Coated Reagents for Solid Phase Immunoassay - Google Patents

Sugar Coated Reagents for Solid Phase Immunoassay

Info

Publication number
GB2016687A
GB2016687A GB7904984A GB7904984A GB2016687A GB 2016687 A GB2016687 A GB 2016687A GB 7904984 A GB7904984 A GB 7904984A GB 7904984 A GB7904984 A GB 7904984A GB 2016687 A GB2016687 A GB 2016687A
Authority
GB
United Kingdom
Prior art keywords
solid phase
sugar coated
phase immunoassay
reagents
coated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7904984A
Other versions
GB2016687B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of GB2016687A publication Critical patent/GB2016687A/en
Application granted granted Critical
Publication of GB2016687B publication Critical patent/GB2016687B/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

An immunoadsorbent coated onto a solid support can be stabilized by employing a sugar coating. Stabilization according to the disclosure will permit dry handling and storage of the coated support. Reagents for use in immunoassay comprise sugar-coated hepatitis antigen or antibody fixed directly or indirectly to for example polystyrene beads.
GB7904984A 1978-03-20 1979-02-13 Sugar coated reagents for solid phase immunoassay Expired GB2016687B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88805178A 1978-03-20 1978-03-20
US382779A 1979-01-16 1979-01-16

Publications (2)

Publication Number Publication Date
GB2016687A true GB2016687A (en) 1979-09-26
GB2016687B GB2016687B (en) 1982-09-08

Family

ID=26672244

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7904984A Expired GB2016687B (en) 1978-03-20 1979-02-13 Sugar coated reagents for solid phase immunoassay

Country Status (9)

Country Link
JP (1) JPS54128396A (en)
AU (1) AU527489B2 (en)
DE (1) DE2910707C2 (en)
ES (1) ES478800A1 (en)
FR (1) FR2420762A1 (en)
GB (1) GB2016687B (en)
IT (1) IT1113315B (en)
NL (1) NL7902152A (en)
SE (1) SE7902389L (en)

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982000058A1 (en) * 1980-06-20 1982-01-07 Porter P Processes and apparatus for carrying out specific binding assays
EP0038960A3 (en) * 1980-04-04 1982-02-03 Toray Industries, Inc. Diagnostic reagents for immunological tests and a process for preparing the same
EP0068344A1 (en) * 1981-06-19 1983-01-05 Eisai Co., Ltd. Method and reagent kit for measurement using an enzyme-labelled antibody
GB2124231A (en) * 1982-05-24 1984-02-15 Corning Glass Works Solid phase reagent for immunoassay
EP0111762A1 (en) * 1980-06-20 1984-06-27 Unilever Plc Processes and apparatus for carrying out specific binding assays
EP0140489A1 (en) * 1983-08-05 1985-05-08 Wako Pure Chemical Industries, Ltd. Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances
WO1986004095A1 (en) * 1985-01-11 1986-07-17 Unilever Nv Preparation of reagents
FR2576107A1 (en) * 1985-01-15 1986-07-18 Cancer Res Inst METHOD OF SEARCHING FOR ANTIBODIES AND EQUIPMENT OR KIT FOR THE IMPLEMENTATION OF THIS METHOD
WO1987000196A1 (en) * 1985-07-09 1987-01-15 Quadrant Bioresources Limited Protection of proteins and the like
EP0153875A3 (en) * 1984-03-01 1987-06-24 The State Of Victoria Enzyme-linked immunosorbent assay method and test kit
GB2187191A (en) * 1984-01-30 1987-09-03 Quadrant Bioresources Ltd Protection of proteins and the like
WO1988008534A1 (en) * 1987-04-27 1988-11-03 Unilever Plc Immunoassays and devices therefor
WO1989000693A1 (en) * 1987-07-16 1989-01-26 Fresenius Limited Protection of proteinaceous reagents
EP0341439A1 (en) * 1988-05-11 1989-11-15 Abbott Laboratories Method for increasing specificity in competitive immunoassays
US4912030A (en) * 1985-01-15 1990-03-27 Institute Of Cancer Research Viral isolates and their use in diagnosis
EP0368624A3 (en) * 1988-11-09 1991-06-05 Biotrack, Inc. Method and composition for stabilizing and solubilizing latex reagents
US5712170A (en) * 1992-12-29 1998-01-27 Oy Medix Biochemica Ab Test strip, its production and use
US5773222A (en) * 1992-05-27 1998-06-30 National Blood Authority Solid phase immunological assay
US6767714B2 (en) 1995-05-02 2004-07-27 Armkel, Llc Diagnostic detection device and method
EP1536231A1 (en) * 2003-11-25 2005-06-01 Eppendorf Ag Method for stabilizing proteins on a micro-array
EP1612557A2 (en) 1999-10-23 2006-01-04 Plasso Technology Limited Binding surface
NL1027931C2 (en) * 2004-12-31 2006-07-03 Univ Delft Tech Assay production method, comprises adding solubility delaying agent or applying cover layers to reagent intended for addition to substrate
EP1288663A4 (en) * 2000-11-20 2007-11-21 Matsushita Electric Industrial Co Ltd EXTRASOMATIC DIAGNOSTICS
EP1691198A4 (en) * 2003-10-28 2008-03-05 Advanced Life Science Inst Inc METHOD OF DETECTING HEPATITIS C VIRUS
WO2008050274A1 (en) * 2006-10-24 2008-05-02 Koninklijke Philips Electronics N.V. Detecting target molecules in a sample
EP2756885A2 (en) 2013-01-16 2014-07-23 Sharp Kabushiki Kaisha Efficient dilution method, including washing method for immunoassay
US10024937B2 (en) 2011-09-27 2018-07-17 Koninklijke Philips N.V. Gradient amplifier with compensation for dead time and forward voltage

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
JPS58187861A (en) * 1982-04-26 1983-11-02 Otsuka Pharmaceut Co Ltd Assay of antibody related to adult type t leukemia
EP0133976A3 (en) * 1983-08-09 1986-07-30 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Reagent for immunoassay
JPS6234059A (en) * 1985-08-07 1987-02-14 Sankyo Co Ltd Stabilizer for solid phase reaction reagent
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5607863A (en) 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5869345A (en) 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5468648A (en) 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1284947A (en) * 1969-05-27 1972-08-09 Abbott Lab Improved lyophilized erythrocyte composition
US3790663A (en) * 1970-07-07 1974-02-05 Us Health Preparation of dry antiserum coated solid-phase for radioimmunoassay of antigens
CH582884A5 (en) * 1973-12-10 1976-12-15 Hoffmann La Roche
SE7610683L (en) * 1975-09-29 1977-06-10 Cordis Corp METHOD OF DETERMINING THE NERVARON OF AN ANTIGEN ASSOCIATE WITH HEPATITIS

Cited By (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0038960A3 (en) * 1980-04-04 1982-02-03 Toray Industries, Inc. Diagnostic reagents for immunological tests and a process for preparing the same
EP0146654A3 (en) * 1980-06-20 1986-08-20 Unilever Plc Processes and apparatus for carrying out specific binding assays
US4889816A (en) * 1980-06-20 1989-12-26 Unilever Patent Holdings B.V. Process and apparatus for carrying out specific binding assays
EP0111762A1 (en) * 1980-06-20 1984-06-27 Unilever Plc Processes and apparatus for carrying out specific binding assays
WO1982000058A1 (en) * 1980-06-20 1982-01-07 Porter P Processes and apparatus for carrying out specific binding assays
EP0042755A3 (en) * 1980-06-20 1982-01-27 Unilever Plc Processes and apparatus for carrying out specific binding assays
EP0068344A1 (en) * 1981-06-19 1983-01-05 Eisai Co., Ltd. Method and reagent kit for measurement using an enzyme-labelled antibody
GB2124231A (en) * 1982-05-24 1984-02-15 Corning Glass Works Solid phase reagent for immunoassay
EP0140489A1 (en) * 1983-08-05 1985-05-08 Wako Pure Chemical Industries, Ltd. Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances
GB2187191B (en) * 1984-01-30 1989-11-01 Quadrant Bioresources Ltd Protection of proteins and the like
GB2187191A (en) * 1984-01-30 1987-09-03 Quadrant Bioresources Ltd Protection of proteins and the like
EP0153875A3 (en) * 1984-03-01 1987-06-24 The State Of Victoria Enzyme-linked immunosorbent assay method and test kit
EP0192320A1 (en) * 1985-01-11 1986-08-27 Unilever Plc Preparation of reagents
WO1986004095A1 (en) * 1985-01-11 1986-07-17 Unilever Nv Preparation of reagents
GB2179449A (en) * 1985-01-15 1987-03-04 Cancer Res Inst Improvements relating to viral isolates and their use
WO1986004423A1 (en) * 1985-01-15 1986-07-31 Institute Of Cancer Research Improvements relating to viral isolates and their use
DE3690028C2 (en) * 1985-01-15 1995-05-24 Cancer Res Inst Method and test kit for analysing a biological sample for antibodies against retroviruses
FR2576107A1 (en) * 1985-01-15 1986-07-18 Cancer Res Inst METHOD OF SEARCHING FOR ANTIBODIES AND EQUIPMENT OR KIT FOR THE IMPLEMENTATION OF THIS METHOD
US4912030A (en) * 1985-01-15 1990-03-27 Institute Of Cancer Research Viral isolates and their use in diagnosis
WO1987000196A1 (en) * 1985-07-09 1987-01-15 Quadrant Bioresources Limited Protection of proteins and the like
EP0560410A3 (en) * 1987-04-27 1993-10-06 Unilever N.V. A test device for performing specific binding assays
EP1555529A3 (en) * 1987-04-27 2008-06-04 Inverness Medical Switzerland GmbH Immunochromatographic specific binding assay device and method.
EP1248112A3 (en) * 1987-04-27 2004-08-25 Inverness Medical Switzerland GmbH Immunochromatographic specific binding assay device
US5602040A (en) * 1987-04-27 1997-02-11 Unilever Patent Holdings B.V. Assays
EP0291194A1 (en) * 1987-04-27 1988-11-17 Unilever N.V. Immunoassays and devices therefor
EP0560411A3 (en) * 1987-04-27 1993-10-06 Unilever N.V. A test device for performing specific binding assays
EP0291194B1 (en) * 1987-04-27 1994-02-16 Unilever N.V. Immunoassays and devices therefor
WO1988008534A1 (en) * 1987-04-27 1988-11-03 Unilever Plc Immunoassays and devices therefor
WO1989000693A1 (en) * 1987-07-16 1989-01-26 Fresenius Limited Protection of proteinaceous reagents
US6150113A (en) * 1988-05-11 2000-11-21 Abbott Laboratories Method for increasing specificity in competitive immunoassays
EP0341439A1 (en) * 1988-05-11 1989-11-15 Abbott Laboratories Method for increasing specificity in competitive immunoassays
EP0368624A3 (en) * 1988-11-09 1991-06-05 Biotrack, Inc. Method and composition for stabilizing and solubilizing latex reagents
US5773222A (en) * 1992-05-27 1998-06-30 National Blood Authority Solid phase immunological assay
US5712170A (en) * 1992-12-29 1998-01-27 Oy Medix Biochemica Ab Test strip, its production and use
US5965458A (en) * 1992-12-29 1999-10-12 Oy Medix Biochemica A.B. Test strip, its production and use
US6767714B2 (en) 1995-05-02 2004-07-27 Armkel, Llc Diagnostic detection device and method
US7045342B2 (en) 1995-05-02 2006-05-16 Church & Dwight Co., Inc. Diagnostic detection device and method
EP1612557A2 (en) 1999-10-23 2006-01-04 Plasso Technology Limited Binding surface
EP1288663A4 (en) * 2000-11-20 2007-11-21 Matsushita Electric Industrial Co Ltd EXTRASOMATIC DIAGNOSTICS
US8546075B2 (en) 2003-10-28 2013-10-01 Advanced Life Science Institute, Inc. Method of detecting hepatitis C virus
EP1691198A4 (en) * 2003-10-28 2008-03-05 Advanced Life Science Inst Inc METHOD OF DETECTING HEPATITIS C VIRUS
EP1536231A1 (en) * 2003-11-25 2005-06-01 Eppendorf Ag Method for stabilizing proteins on a micro-array
NL1027931C2 (en) * 2004-12-31 2006-07-03 Univ Delft Tech Assay production method, comprises adding solubility delaying agent or applying cover layers to reagent intended for addition to substrate
WO2008050274A1 (en) * 2006-10-24 2008-05-02 Koninklijke Philips Electronics N.V. Detecting target molecules in a sample
US10101321B2 (en) 2006-10-24 2018-10-16 Koninklijke Philips N.V. Detecting target molecules in a sample
US10670589B2 (en) 2006-10-24 2020-06-02 Koninklijke Philips N.V. Detecting target molecules in a sample
US10024937B2 (en) 2011-09-27 2018-07-17 Koninklijke Philips N.V. Gradient amplifier with compensation for dead time and forward voltage
EP2756885A2 (en) 2013-01-16 2014-07-23 Sharp Kabushiki Kaisha Efficient dilution method, including washing method for immunoassay
US9492824B2 (en) 2013-01-16 2016-11-15 Sharp Kabushiki Kaisha Efficient dilution method, including washing method for immunoassay

Also Published As

Publication number Publication date
IT1113315B (en) 1986-01-20
JPS54128396A (en) 1979-10-04
DE2910707C2 (en) 1982-05-27
ES478800A1 (en) 1980-01-16
AU4419579A (en) 1979-09-27
DE2910707A1 (en) 1979-10-04
SE7902389L (en) 1979-09-21
IT7921112A0 (en) 1979-03-19
FR2420762A1 (en) 1979-10-19
AU527489B2 (en) 1983-03-10
GB2016687B (en) 1982-09-08
NL7902152A (en) 1979-09-24
JPH02673B2 (en) 1990-01-09

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee