GB2012260B - 4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents - Google Patents

4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents

Info

Publication number: GB2012260B
Authority: GB; United Kingdom
Prior art keywords: dihydroindoles; desacetoxy; hydroxyindole; pharmaceutical formulations; formulations containing
Prior art date: 1977-11-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB7843032A

Other versions

GB2012260A (en

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-07

Filing date

1978-11-02

Publication date

1982-11-03

1977-11-07 Priority claimed from US05/848,837 external-priority patent/US4122082A/en

1978-03-27 Priority claimed from US05/890,422 external-priority patent/US4195022A/en

1978-11-02 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1979-07-25 Publication of GB2012260A publication Critical patent/GB2012260A/en

1982-11-03 Application granted granted Critical

1982-11-03 Publication of GB2012260B publication Critical patent/GB2012260B/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

GB7843032A 1977-11-07 1978-11-02 4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents Expired GB2012260B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US05/848,837 US4122082A (en)	1977-11-07	1977-11-07	4-Desacetoxy-4-oxovinblastine
US05/890,422 US4195022A (en)	1978-03-27	1978-03-27	4-Desacetoxy-4α-hydroxyvinblastine and related compounds

Publications (2)

Publication Number	Publication Date
GB2012260A GB2012260A (en)	1979-07-25
GB2012260B true GB2012260B (en)	1982-11-03

Family

ID=27126805

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
GB8200664A Expired GB2089806B (en)	1977-11-07	1978-11-02	4-desacetoxy-oxo-indole-dyhydroindole intermediates
GB7843032A Expired GB2012260B (en)	1977-11-07	1978-11-02	4-desacetoxy 4 hydroxyindole dihydroindoles pharmaceutical formulations containing them and their use as antimitotic agents

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
GB8200664A Expired GB2089806B (en)	1977-11-07	1978-11-02	4-desacetoxy-oxo-indole-dyhydroindole intermediates

Country Status (11)

Country	Link
JP (1)	JPS5473796A (en)
AR (1)	AR227620A1 (en)
CH (1)	CH638814A5 (en)
DK (1)	DK147302C (en)
FR (1)	FR2407935A1 (en)
GB (2)	GB2089806B (en)
HU (1)	HU184623B (en)
IE (1)	IE47489B1 (en)
IL (1)	IL55865A (en)
IT (1)	IT1100920B (en)
LU (1)	LU80474A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU185691B (en) *	1982-02-09	1985-03-28	Richter Gedeon Vegyeszet	Process for preparing a new analgetic pharmaceutical composition
FR2894966B1 (en) *	2005-12-20	2008-03-14	Pierre Fabre Medicament Sa	NEW CRYSTALLINE FORM OF VINFLUNINE
USD973040S1 (en) *	2020-11-06	2022-12-20	Lite-On Electronics (Guangzhou) Limited	Antenna monitoring tool box

1978
- 1978-11-02 GB GB8200664A patent/GB2089806B/en not_active Expired
- 1978-11-02 GB GB7843032A patent/GB2012260B/en not_active Expired
- 1978-11-03 AR AR274332A patent/AR227620A1/en active
- 1978-11-03 LU LU80474A patent/LU80474A1/en unknown
- 1978-11-03 IT IT29435/78A patent/IT1100920B/en active
- 1978-11-03 IL IL55865A patent/IL55865A/en unknown
- 1978-11-03 FR FR7831134A patent/FR2407935A1/en active Granted
- 1978-11-04 HU HU78EI818A patent/HU184623B/en unknown
- 1978-11-06 CH CH1141978A patent/CH638814A5/en not_active IP Right Cessation
- 1978-11-06 IE IE2189/78A patent/IE47489B1/en unknown
- 1978-11-06 DK DK494178A patent/DK147302C/en not_active IP Right Cessation
- 1978-11-07 JP JP13723678A patent/JPS5473796A/en active Pending

Also Published As

Publication number	Publication date
JPS5473796A (en)	1979-06-13
AR227620A1 (en)	1982-11-30
HU184623B (en)	1984-09-28
FR2407935B1 (en)	1981-06-26
IT7829435A0 (en)	1978-11-03
LU80474A1 (en)	1979-03-19
IL55865A (en)	1982-11-30
GB2089806A (en)	1982-06-30
GB2012260A (en)	1979-07-25
GB2089806B (en)	1982-11-24
IE782189L (en)	1979-05-07
DK147302B (en)	1984-06-12
IL55865A0 (en)	1979-01-31
FR2407935A1 (en)	1979-06-01
IE47489B1 (en)	1984-04-04
DK494178A (en)	1979-05-08
IT1100920B (en)	1985-09-28
CH638814A5 (en)	1983-10-14
DK147302C (en)	1985-01-02

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Legal Events

Date	Code	Title	Description
1985-06-26	PCNP	Patent ceased through non-payment of renewal fee