GB1432354A - Compounds having a physiological cooling effect and compo sitions containing them - Google Patents
Compounds having a physiological cooling effect and compo sitions containing themInfo
- Publication number
- GB1432354A GB1432354A GB4903972A GB4903972A GB1432354A GB 1432354 A GB1432354 A GB 1432354A GB 4903972 A GB4903972 A GB 4903972A GB 4903972 A GB4903972 A GB 4903972A GB 1432354 A GB1432354 A GB 1432354A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sulphoxide
- stimulant
- alkyl
- carbon atoms
- tobacco
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 title 1
- 238000001816 cooling Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 241000208125 Nicotiana Species 0.000 abstract 3
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 2
- 125000001174 sulfone group Chemical group 0.000 abstract 2
- GTALHHCTFKIKHC-UHFFFAOYSA-N 1-(2,3-dimethylbutan-2-ylsulfinyl)hexane Chemical compound CCCCCCS(=O)C(C)(C)C(C)C GTALHHCTFKIKHC-UHFFFAOYSA-N 0.000 abstract 1
- LOWMYOWHQMKBTM-UHFFFAOYSA-N 1-butylsulfinylbutane Chemical compound CCCCS(=O)CCCC LOWMYOWHQMKBTM-UHFFFAOYSA-N 0.000 abstract 1
- JMTPSGIOISIVKY-UHFFFAOYSA-N 2-methyl-3-propylsulfonylnonane Chemical compound CCCCCCC(C(C)C)S(=O)(=O)CCC JMTPSGIOISIVKY-UHFFFAOYSA-N 0.000 abstract 1
- JAPGNJKVTTYBIF-UHFFFAOYSA-N 3-methyl-3-propan-2-ylsulfinylpentane Chemical compound CCC(C)(CC)S(=O)C(C)C JAPGNJKVTTYBIF-UHFFFAOYSA-N 0.000 abstract 1
- NCXXWKPCZBXFTP-UHFFFAOYSA-N 4-methyl-2-methylsulfinyl-1-propan-2-ylcyclohexane Chemical compound CC(C)C1CCC(C)CC1S(C)=O NCXXWKPCZBXFTP-UHFFFAOYSA-N 0.000 abstract 1
- 235000010585 Ammi visnaga Nutrition 0.000 abstract 1
- 244000153158 Ammi visnaga Species 0.000 abstract 1
- JOKOVGITVRPHME-UHFFFAOYSA-N C1(CCCCC1)S(=O)C(C(C)C)CCCC Chemical compound C1(CCCCC1)S(=O)C(C(C)C)CCCC JOKOVGITVRPHME-UHFFFAOYSA-N 0.000 abstract 1
- 235000013361 beverage Nutrition 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 235000019504 cigarettes Nutrition 0.000 abstract 1
- 239000000551 dentifrice Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 239000002778 food additive Substances 0.000 abstract 1
- 235000013373 food additive Nutrition 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/22—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/202—Aliphatic compounds
- A23L27/2022—Aliphatic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/203—Alicyclic compounds
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q13/00—Formulations or additives for perfume preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/12—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/244—Endothermic; Cooling; Cooling sensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/002—Aftershave preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q9/00—Preparations for removing hair or for aiding hair removal
- A61Q9/02—Shaving preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Cosmetics (AREA)
- Manufacture Of Tobacco Products (AREA)
- Fats And Perfumes (AREA)
- Seasonings (AREA)
- Medicinal Preparation (AREA)
- Noodles (AREA)
Abstract
1432354 Tobacco and food additives WILKINSON SWORD Ltd 19 July 1973 [20 July 1972 24 Oct 1972] 33994/72 and 49039/72 Headings A2B and A2C [Also in Divisions A5 and C5] A composition capable of stimulating the cold receptors of the nervous system of the human body comprises a cold receptor stimulant and a carrier thereof, the stimulant being a sulphoxide or sulphone of formula RSO x R<SP>10</SP> wherein R<SP>10</SP> is alkyl, optionally containing carboxy or alkoxycarbonyl substituents; x is 1 or 2; and R is either where R 1 is H or C 1-5 alkyl, R 2 is C 1-6 alkyl, R 3 is C 1-8 alkyl, R 1 , R 2 and R 3 together provide a total of 3-15 carbon atoms, and with R<SP>1</SP> 6-18 carbon atoms, with the proviso that, when R, is H and x is 1, then at least one of R 2 , R 3 and R 10 is branched; or R is wherein R* is C 1-5 alkyl, n is 0, or an integer from 1 to 4 and the total number of carbon atoms provided by R* and R<SP>10</SP> is from 2 to 12. The stimulant may be used in an ingestible composition, topically administrable composition, lotion, dentifrice, ointment, or pharmaceutical composition. The stimulant may be impregnated in a cleansing tissue, or a tooth pick. The stimulant may be incorporated with suitable flavourants and colourants into comestible compositions and beverages. The stimulant may also be incorporated into tobacco preparations such as tobacco and cigarette filter tips. Typical sulphoxides and sulphones exemplified are 3-methyl pent-3-yl isopropyl sulphoxide, n-hexyl 2, 3-dimethylbut-3-yl sulphoxide, 2-methyl non-3-yl propyl sulphone, di-sec. butyl sulphoxide, p-menth-3- yl methyl sulphoxide, ethyl carboxymethyl-pmenth-3-yl sulphoxide and n-butyl 1-isobutyl cyclohexyl sulphoxide.
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4903972A GB1432354A (en) | 1972-07-20 | 1972-10-24 | Compounds having a physiological cooling effect and compo sitions containing them |
| DE19732334985 DE2334985A1 (en) | 1972-07-20 | 1973-07-10 | Means of stimulating the cold receptors of the human nervous system and their use |
| AU58020/73A AU477675B2 (en) | 1972-07-20 | 1973-07-12 | Improvements in and relating to compounds having physiological cooling effect and compositions containing them |
| IL42735A IL42735A (en) | 1972-07-20 | 1973-07-13 | Compositions containing (cyclo) alkyl alkyl sulfones and sulfoxides having a physiological cooling effect |
| AT626273A AT330362B (en) | 1972-07-20 | 1973-07-16 | COOLANT |
| HUWI234A HU167694B (en) | 1972-07-20 | 1973-07-17 | |
| LU68036A LU68036A1 (en) | 1972-07-20 | 1973-07-18 | |
| EG282/73A EG10911A (en) | 1972-07-20 | 1973-07-18 | Improvements in and relating to compounds having a physiological cooling effect and compositions containing them |
| CH1053373A CH576240A5 (en) | 1972-07-20 | 1973-07-18 | |
| NL7310022A NL7310022A (en) | 1972-07-20 | 1973-07-18 | |
| JP48082538A JPS4985245A (en) | 1972-07-20 | 1973-07-19 | |
| RO7375536A RO67322A2 (en) | 1972-07-20 | 1973-07-19 | DEODORANT COMPOSITION |
| FR7326588A FR2193603B1 (en) | 1972-07-20 | 1973-07-19 | |
| US05/381,097 US4070449A (en) | 1972-10-24 | 1973-07-20 | Compounds having a physiological cooling effect and compositions containing them |
| IE1237/73A IE37935B1 (en) | 1972-07-20 | 1973-07-20 | Improvements in and relating to compounds having a physiological cooling effect and compositions containing them |
| IT26885/73A IT1048130B (en) | 1972-07-20 | 1973-07-20 | IMPROVEMENTS TO COMPOUNDS HAVING A REFRESHING PHYSIOLOGICAL EFFECT AND COMPOSITIONS CONTAINING THESE COMPOUNDS |
| DD172413A DD105390A5 (en) | 1972-07-20 | 1973-07-20 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3399472 | 1972-07-20 | ||
| GB4903972A GB1432354A (en) | 1972-07-20 | 1972-10-24 | Compounds having a physiological cooling effect and compo sitions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1432354A true GB1432354A (en) | 1976-04-14 |
Family
ID=26262117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4903972A Expired GB1432354A (en) | 1972-07-20 | 1972-10-24 | Compounds having a physiological cooling effect and compo sitions containing them |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4985245A (en) |
| AT (1) | AT330362B (en) |
| CH (1) | CH576240A5 (en) |
| DD (1) | DD105390A5 (en) |
| DE (1) | DE2334985A1 (en) |
| EG (1) | EG10911A (en) |
| FR (1) | FR2193603B1 (en) |
| GB (1) | GB1432354A (en) |
| HU (1) | HU167694B (en) |
| IE (1) | IE37935B1 (en) |
| IL (1) | IL42735A (en) |
| IT (1) | IT1048130B (en) |
| LU (1) | LU68036A1 (en) |
| NL (1) | NL7310022A (en) |
| RO (1) | RO67322A2 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277385B1 (en) | 1992-06-17 | 2001-08-21 | The Procter & Gamble Company | Cooling compositions with reduced stinging |
| EP1205116A3 (en) * | 2000-11-09 | 2003-11-12 | INTERNATIONAL FLAVORS & FRAGRANCES INC. | Oral sensory perception-affecting compositions containing dimethyl sulfoxide |
| WO2013121407A1 (en) * | 2012-02-17 | 2013-08-22 | Budhi Haryanto | The composition of malodor removing aerosol for daily worn objects or items |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3527864A (en) * | 1966-11-18 | 1970-09-08 | Procter & Gamble | Compositions for topical application to animal tissue and method of enhancing penetration thereof |
-
1972
- 1972-10-24 GB GB4903972A patent/GB1432354A/en not_active Expired
-
1973
- 1973-07-10 DE DE19732334985 patent/DE2334985A1/en active Pending
- 1973-07-13 IL IL42735A patent/IL42735A/en unknown
- 1973-07-16 AT AT626273A patent/AT330362B/en not_active IP Right Cessation
- 1973-07-17 HU HUWI234A patent/HU167694B/hu unknown
- 1973-07-18 CH CH1053373A patent/CH576240A5/xx not_active IP Right Cessation
- 1973-07-18 NL NL7310022A patent/NL7310022A/xx unknown
- 1973-07-18 EG EG282/73A patent/EG10911A/en active
- 1973-07-18 LU LU68036A patent/LU68036A1/xx unknown
- 1973-07-19 FR FR7326588A patent/FR2193603B1/fr not_active Expired
- 1973-07-19 JP JP48082538A patent/JPS4985245A/ja active Pending
- 1973-07-19 RO RO7375536A patent/RO67322A2/en unknown
- 1973-07-20 IE IE1237/73A patent/IE37935B1/en unknown
- 1973-07-20 IT IT26885/73A patent/IT1048130B/en active
- 1973-07-20 DD DD172413A patent/DD105390A5/xx unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277385B1 (en) | 1992-06-17 | 2001-08-21 | The Procter & Gamble Company | Cooling compositions with reduced stinging |
| EP1205116A3 (en) * | 2000-11-09 | 2003-11-12 | INTERNATIONAL FLAVORS & FRAGRANCES INC. | Oral sensory perception-affecting compositions containing dimethyl sulfoxide |
| WO2013121407A1 (en) * | 2012-02-17 | 2013-08-22 | Budhi Haryanto | The composition of malodor removing aerosol for daily worn objects or items |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4985245A (en) | 1974-08-15 |
| FR2193603B1 (en) | 1977-07-15 |
| FR2193603A1 (en) | 1974-02-22 |
| RO67322A2 (en) | 1982-09-09 |
| AT330362B (en) | 1976-06-25 |
| IE37935B1 (en) | 1977-11-23 |
| DD105390A5 (en) | 1974-04-20 |
| DE2334985A1 (en) | 1974-02-07 |
| AU5802073A (en) | 1975-01-16 |
| ATA626273A (en) | 1975-09-15 |
| CH576240A5 (en) | 1976-06-15 |
| NL7310022A (en) | 1974-01-22 |
| HU167694B (en) | 1975-11-28 |
| EG10911A (en) | 1976-10-31 |
| IE37935L (en) | 1974-01-20 |
| IT1048130B (en) | 1980-11-20 |
| IL42735A0 (en) | 1973-10-25 |
| LU68036A1 (en) | 1973-09-26 |
| IL42735A (en) | 1977-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |