GB1478819A - Derivatives of aminomethylcyclohexanecarboxylic acid - Google Patents
Derivatives of aminomethylcyclohexanecarboxylic acidInfo
- Publication number
- GB1478819A GB1478819A GB3209775A GB3209775A GB1478819A GB 1478819 A GB1478819 A GB 1478819A GB 3209775 A GB3209775 A GB 3209775A GB 3209775 A GB3209775 A GB 3209775A GB 1478819 A GB1478819 A GB 1478819A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- derivatives
- compound
- aminomethylcyclohexanecarboxylic acid
- antihyperlipidic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UAFHRUBCOQPFFM-UHFFFAOYSA-N 1-(aminomethyl)cyclohexane-1-carboxylic acid Chemical class NCC1(C(O)=O)CCCCC1 UAFHRUBCOQPFFM-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000879 anti-atherosclerotic effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 230000001147 anti-toxic effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000002178 gastroprotective effect Effects 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1478819 Aminomethylcyclohexane carboxylic acid derivatives RORER ITALIANA SpA 31 July 1975 [1 Aug 1974] 32097/75 Heading C2C Novel compounds of Formula I wherein R<SP>1</SP> is H or C 1-6 alkyl and R is CnH 2n+n1 -CO- where n is an integer from 4 to 20 and n<SP>1</SP> is + 1, - 1, - 3 or - 5 and salts thereof with Na, K, Ca, Mg, A1 and amino acids and prepared by reaction of a compound of Formula II with an acid halide R-halogen and optimal salt formation. Pharmaceutical compositions in conventional forms and having antitoxic, antihyperlipidic, antiatherosclerosis, antiphlogistic and gastroprotective activity comprise an above novel compound and a carrier or diluent.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7426767A FR2280365A1 (en) | 1974-08-01 | 1974-08-01 | ALKANOYLIC DERIVATIVES OF AMINOMETHYLCYCLOHEXANECARBOXYLIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1478819A true GB1478819A (en) | 1977-07-06 |
Family
ID=9141987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3209775A Expired GB1478819A (en) | 1974-08-01 | 1975-07-31 | Derivatives of aminomethylcyclohexanecarboxylic acid |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS5139653A (en) |
| BE (1) | BE831825A (en) |
| CA (1) | CA1069532A (en) |
| DE (1) | DE2533930A1 (en) |
| FR (1) | FR2280365A1 (en) |
| GB (1) | GB1478819A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117342971A (en) * | 2023-09-28 | 2024-01-05 | 上海优斐斯生物科技有限公司 | Fatty acyl coagulates, and preparation method and application thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6011685B2 (en) * | 1977-04-21 | 1985-03-27 | 呉羽化学工業株式会社 | Trans-4-aminomethylcyclohexane-1-carboxylic acid derivative cancer drug |
-
1974
- 1974-08-01 FR FR7426767A patent/FR2280365A1/en active Granted
-
1975
- 1975-07-28 BE BE158693A patent/BE831825A/en unknown
- 1975-07-30 DE DE19752533930 patent/DE2533930A1/en not_active Withdrawn
- 1975-07-31 GB GB3209775A patent/GB1478819A/en not_active Expired
- 1975-07-31 CA CA232640A patent/CA1069532A/en not_active Expired
- 1975-08-01 JP JP9322775A patent/JPS5139653A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117342971A (en) * | 2023-09-28 | 2024-01-05 | 上海优斐斯生物科技有限公司 | Fatty acyl coagulates, and preparation method and application thereof |
| CN117342971B (en) * | 2023-09-28 | 2024-03-19 | 上海优斐斯生物科技有限公司 | Fatty acyl coagulates, and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5139653A (en) | 1976-04-02 |
| BE831825A (en) | 1976-01-28 |
| DE2533930A1 (en) | 1976-02-19 |
| CA1069532A (en) | 1980-01-08 |
| FR2280365A1 (en) | 1976-02-27 |
| FR2280365B1 (en) | 1978-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 746 | Register noted 'licences of right' (sect. 46/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |