GB1468333A - Ketoglutaric acid derivatives - Google Patents
Ketoglutaric acid derivativesInfo
- Publication number
- GB1468333A GB1468333A GB3393475A GB3393475A GB1468333A GB 1468333 A GB1468333 A GB 1468333A GB 3393475 A GB3393475 A GB 3393475A GB 3393475 A GB3393475 A GB 3393475A GB 1468333 A GB1468333 A GB 1468333A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ketoglutaric acid
- acid derivatives
- vincamine
- salt
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KPGXRSRHYNQIFN-UHFFFAOYSA-N 2-oxoglutaric acid Chemical class OC(=O)CCC(=O)C(O)=O KPGXRSRHYNQIFN-UHFFFAOYSA-N 0.000 title abstract 5
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical class C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 abstract 4
- HWXBTNAVRSUOJR-UHFFFAOYSA-N alpha-hydroxyglutaric acid Natural products OC(=O)C(O)CCC(O)=O HWXBTNAVRSUOJR-UHFFFAOYSA-N 0.000 abstract 2
- 229940009533 alpha-ketoglutaric acid Drugs 0.000 abstract 2
- 206010054880 Vascular insufficiency Diseases 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000023577 vascular insufficiency disease Diseases 0.000 abstract 1
- 229960002726 vincamine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/347—Saturated compounds containing more than one carboxyl group containing keto groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1468333 Vincamine salt J A C GUBERN 14 Aug 1975 [14 Sept 1974] 33934/75 Heading C2C The invention comprises the vincamine salt of alpha-ketoglutaric acid. The compound is prepared by reacting vincamine with alphaketoglutaric acid. The salt may be used to treat cerebral vascular insufficiency.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES430063A ES430063A1 (en) | 1974-09-14 | 1974-09-14 | Ketoglutaric acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1468333A true GB1468333A (en) | 1977-03-23 |
Family
ID=8467553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3393475A Expired GB1468333A (en) | 1974-09-14 | 1975-08-14 | Ketoglutaric acid derivatives |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE833146A (en) |
| ES (1) | ES430063A1 (en) |
| FR (1) | FR2284325A1 (en) |
| GB (1) | GB1468333A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU719877B2 (en) * | 1995-04-12 | 2000-05-18 | Covex Farma S.L. | A new composition which stimulates cerebral activity, based upon alkaloids with an eburnamenine nucleus, and methods for their preparation |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4362730A (en) * | 1980-08-25 | 1982-12-07 | Heinrich Mack Nachf. Chem-Pharm. Fabrik | Vincamine saccharinate and a pharmaceutical composition containing it dissolved therein |
| CH663789A5 (en) * | 1985-08-27 | 1988-01-15 | Arysearch Arylan Ag | PROCEDURE FOR THE PRODUCTION OF VINCAMINA 2-KETOGLUTARATE SALT. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2179538B1 (en) * | 1972-04-11 | 1975-04-25 | Merrell Toraude & Co | |
| FR2202682A1 (en) * | 1972-10-12 | 1974-05-10 | Made Labor Sa | Pyridoxal and pyridoxamine alpha-ketoglutarates - as agents to improve intellectual and physical states |
-
1974
- 1974-09-14 ES ES430063A patent/ES430063A1/en not_active Expired
-
1975
- 1975-08-14 GB GB3393475A patent/GB1468333A/en not_active Expired
- 1975-09-08 BE BE2054551A patent/BE833146A/en not_active IP Right Cessation
- 1975-09-12 FR FR7528893A patent/FR2284325A1/en active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU719877B2 (en) * | 1995-04-12 | 2000-05-18 | Covex Farma S.L. | A new composition which stimulates cerebral activity, based upon alkaloids with an eburnamenine nucleus, and methods for their preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| ES430063A1 (en) | 1976-10-01 |
| FR2284325B1 (en) | 1979-07-27 |
| BE833146A (en) | 1975-12-31 |
| FR2284325A1 (en) | 1976-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 48S | Specification amended (sect. 8/1949) | ||
| SP | Amendment (slips) printed | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19930814 |