GB1329693A - Haemostatic surgical dressing and a method of manaufacturing same - Google Patents
Haemostatic surgical dressing and a method of manaufacturing sameInfo
- Publication number
- GB1329693A GB1329693A GB1329693DA GB1329693A GB 1329693 A GB1329693 A GB 1329693A GB 1329693D A GB1329693D A GB 1329693DA GB 1329693 A GB1329693 A GB 1329693A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alginate
- polymer
- substrate
- weight
- haemostatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940030225 antihemorrhagics Drugs 0.000 title abstract 5
- 230000000025 haemostatic effect Effects 0.000 title abstract 5
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 abstract 6
- 229940072056 alginate Drugs 0.000 abstract 6
- 235000010443 alginic acid Nutrition 0.000 abstract 6
- 229920000615 alginic acid Polymers 0.000 abstract 6
- 239000000463 material Substances 0.000 abstract 6
- 229920000642 polymer Polymers 0.000 abstract 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 239000000758 substrate Substances 0.000 abstract 3
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 abstract 2
- 229930182830 galactose Natural products 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 235000010413 sodium alginate Nutrition 0.000 abstract 2
- 239000000661 sodium alginate Substances 0.000 abstract 2
- 229940005550 sodium alginate Drugs 0.000 abstract 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 abstract 1
- QZCLKYGREBVARF-UHFFFAOYSA-N Acetyl tributyl citrate Chemical compound CCCCOC(=O)CC(C(=O)OCCCC)(OC(C)=O)CC(=O)OCCCC QZCLKYGREBVARF-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 abstract 1
- 239000004348 Glyceryl diacetate Substances 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 abstract 1
- 229920002230 Pectic acid Polymers 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 239000004372 Polyvinyl alcohol Substances 0.000 abstract 1
- VEUACKUBDLVUAC-UHFFFAOYSA-N [Na].[Ca] Chemical compound [Na].[Ca] VEUACKUBDLVUAC-UHFFFAOYSA-N 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 229960000458 allantoin Drugs 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 235000010410 calcium alginate Nutrition 0.000 abstract 1
- 239000000648 calcium alginate Substances 0.000 abstract 1
- 229960002681 calcium alginate Drugs 0.000 abstract 1
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 238000005266 casting Methods 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 235000019443 glyceryl diacetate Nutrition 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 239000010318 polygalacturonic acid Substances 0.000 abstract 1
- 229920002689 polyvinyl acetate Polymers 0.000 abstract 1
- 239000011118 polyvinyl acetate Substances 0.000 abstract 1
- 229920002451 polyvinyl alcohol Polymers 0.000 abstract 1
- 229920000915 polyvinyl chloride Polymers 0.000 abstract 1
- 239000004800 polyvinyl chloride Substances 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/225—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
1329693 Alginate material WALLACE CAMERON & CO Ltd 7 Sept 1970 [27 Sept 1969] 47643/69 Heading C3U [Also in Divisions A5 and B2] A surgical dressing comprises a haemostatic material on a substrate, the haemostatic material comprising an alginate and a water-soluble polymer. The substrate may be a thin polyvinyl chloride sheet. The alginate may be sodium alginate, calcium alginate or calcium sodium alginate or a mixture thereof. The polymer is at least one of polyvinylacetate/polyvinylpyrrolidone copolymers; sodium carboxymethyl cellulose ; polyethylene oxide; poly(galactose methacrylate); poly(galactose acrylate); methyl vinyl ether/maleic anhydride copolymers; allantoin polygalacturonic acid; and polyvinyl alcohol. The haemostatic material may comprise 15- 85% by weight alginate and 85-15% by weight polymer. A total of up to 15% by weight of the haemostatic material of a local anaesthetic, antiseptic or plasticizer (e.g. at least one of glycerol, diacetin, dibutyl phthalate and acetyl tributyl citrate) may be present. The material may be in the form of block, sheet or film, and may be formed by mixing the alginate, polymer and a liquid vehicle and forming a solid from the resulting mixture by casting on to a substrate. Preferably an aqueous solution or suspension of the alginate is mixed with an aqueous solution of polymer.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4764369 | 1969-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1329693A true GB1329693A (en) | 1973-09-12 |
Family
ID=10445744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1329693D Expired GB1329693A (en) | 1969-09-27 | 1969-09-27 | Haemostatic surgical dressing and a method of manaufacturing same |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1329693A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022203A (en) * | 1976-01-22 | 1977-05-10 | Win Ackley | Treated patch for minor cuts |
| EP0243069A3 (en) * | 1986-04-17 | 1989-02-22 | Johnson & Johnson Products Inc. | Adhesive wound dressing |
| GB2221620A (en) * | 1988-07-29 | 1990-02-14 | Johnson & Johnson Patient Care | Haemostatic wound dressing material |
| WO1990014110A1 (en) * | 1989-05-16 | 1990-11-29 | Jean Vilain | Improvements in or relating to pharmaceutical preparations |
| EP0459378A1 (en) * | 1990-05-30 | 1991-12-04 | FIDIA S.p.A. | Gels in the form of highly hydrated self-supporting film, the process for their preparation, and their use in the therapy of cutaneous lesions and/or pathologies |
| US6075177A (en) * | 1993-01-22 | 2000-06-13 | Acordis Fibres (Holdings) Limited | Wound dressing |
| US6372248B1 (en) * | 1994-10-28 | 2002-04-16 | Innovative Technologies Limited | Dehydrated hydrogels |
| WO2002076518A1 (en) * | 2001-03-27 | 2002-10-03 | Bristol-Myers Squibb Company | Wound dressing |
| GB2435425A (en) * | 2006-02-23 | 2007-08-29 | Christian Stephenson | Wound healing system and dressing containing sodium alginate and/or calcium alginate powder |
| WO2008059266A3 (en) * | 2006-11-17 | 2009-07-23 | Medtrade Products Ltd | Medical device |
-
1969
- 1969-09-27 GB GB1329693D patent/GB1329693A/en not_active Expired
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022203A (en) * | 1976-01-22 | 1977-05-10 | Win Ackley | Treated patch for minor cuts |
| EP0243069A3 (en) * | 1986-04-17 | 1989-02-22 | Johnson & Johnson Products Inc. | Adhesive wound dressing |
| GB2221620A (en) * | 1988-07-29 | 1990-02-14 | Johnson & Johnson Patient Care | Haemostatic wound dressing material |
| GB2221620B (en) * | 1988-07-29 | 1991-09-04 | Johnson & Johnson Patient Care | Haemostatic wound dressing material |
| WO1990014110A1 (en) * | 1989-05-16 | 1990-11-29 | Jean Vilain | Improvements in or relating to pharmaceutical preparations |
| US5709877A (en) * | 1990-05-30 | 1998-01-20 | Fidia S.P.A. | Gels in the form of highly hydrated self-supporting film, the process for their preparation, and their use in the therapy of cutaneous lesions and/or pathologies |
| US5523093A (en) * | 1990-05-30 | 1996-06-04 | Fidia, S.P.A. | Gels in the form of highly hydrated self-supporting film, the process for their preparation, and their use in the therapy of cutaneous lesions and/or pathologies |
| US5618561A (en) * | 1990-05-30 | 1997-04-08 | Fidia S.P.A. | Preparation of highly hydrated self-supporting hyaluronic acid containing films |
| EP0459378A1 (en) * | 1990-05-30 | 1991-12-04 | FIDIA S.p.A. | Gels in the form of highly hydrated self-supporting film, the process for their preparation, and their use in the therapy of cutaneous lesions and/or pathologies |
| US6075177A (en) * | 1993-01-22 | 2000-06-13 | Acordis Fibres (Holdings) Limited | Wound dressing |
| US6372248B1 (en) * | 1994-10-28 | 2002-04-16 | Innovative Technologies Limited | Dehydrated hydrogels |
| WO2002076518A1 (en) * | 2001-03-27 | 2002-10-03 | Bristol-Myers Squibb Company | Wound dressing |
| GB2435425A (en) * | 2006-02-23 | 2007-08-29 | Christian Stephenson | Wound healing system and dressing containing sodium alginate and/or calcium alginate powder |
| GB2435425B (en) * | 2006-02-23 | 2011-06-29 | Christian Stephenson | Medical wound healing treatment |
| WO2008059266A3 (en) * | 2006-11-17 | 2009-07-23 | Medtrade Products Ltd | Medical device |
| US9370451B2 (en) | 2006-11-17 | 2016-06-21 | Medtrade Products Limited | Medical device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 435 | Patent endorsed 'licences of right' on the date specified (sect. 35/1949) | ||
| PE20 | Patent expired after termination of 20 years |