[go: up one dir, main page]

GB1304174A - - Google Patents

Info

Publication number
GB1304174A
GB1304174A GB1215869A GB1304174DA GB1304174A GB 1304174 A GB1304174 A GB 1304174A GB 1215869 A GB1215869 A GB 1215869A GB 1304174D A GB1304174D A GB 1304174DA GB 1304174 A GB1304174 A GB 1304174A
Authority
GB
United Kingdom
Prior art keywords
compound
phenyl
biphenylyl
dimethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1215869A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1304174A publication Critical patent/GB1304174A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/10—The polymethine chain containing an even number of >CH- groups
    • C09B23/105—The polymethine chain containing an even number of >CH- groups two >CH- groups
    • H10W70/635—

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1304174 Pyrrylvinylthiazolium salts WELL- - COME FOUNDATION Ltd (Burroughs Wellcome & Co USA Inc) 5 March 1970 [7 March 1969] 12158/69 Headings C2C and C2P Compounds (I): (where R is 1-6C alkyl or optionally substituted phenyl; Z is Ph, p-halophenyl, p-alkoxyphenyl, biphenylyl, p-alkoxy biphenylyl or naphthyl and X- is the anion of a pharmaceutically acceptable acid) are prepared (1) by reacting a compound (II) with a compound: (III): and optionally forming the salt or (2) by ring closure of a compound (IV): in which the compound IV may be prepared in situ by reacting a compound (V): with a compound Z-CO-CH 2 A. The following starting materials are prepared: 2 - methyl - 4 - p - biphenylyl thiazole and its methiodide; 2,5 - dimethyl - 1 - phenylpyrrole and 1 - phenyl - 2,5 - dimethylpyrrole - 3 - carboxaldehyde; 3 - (2,5 - dimethyl - 1 - phenylpyrrol-3-yl) acrylomethylamide and its thioamide and p - phenyl - phenacyl - N - methyl - 3- (2,5 - dimethyl - 1 - phenyl - pyrrol - 3 - yl)- acrylothioimidate - HBr; 3 - (1,2,5 - trimethylpyrrol - 3 - yl) acrylomethylamide and its thioamide and p - bromophenacyl - N - methyl - 3- (1,2,5 - trimethylpyrrol - 3 - yl) acrylothioimidate HBr, and N-methylcarbamoylmethyltriphenylphosphonium chloride. Pharmaceutical compositions useful in treating nematode infection are in forms suitable for oral administration.
GB1215869A 1969-03-07 1969-03-07 Expired GB1304174A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1215869 1969-03-07
US1594470A 1970-03-02 1970-03-02
US00215926A US3851060A (en) 1969-03-07 1972-01-06 Composition and methods for treating nematode infections

Publications (1)

Publication Number Publication Date
GB1304174A true GB1304174A (en) 1973-01-24

Family

ID=27256795

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1215869A Expired GB1304174A (en) 1969-03-07 1969-03-07

Country Status (9)

Country Link
US (1) US3851060A (en)
BE (1) BE746998A (en)
CA (1) CA960667A (en)
CH (2) CH574958A5 (en)
DE (1) DE2010490A1 (en)
FR (1) FR2096715B1 (en)
GB (1) GB1304174A (en)
NL (1) NL7003246A (en)
SE (1) SE368709B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298743A (en) * 1979-09-11 1981-11-03 Merck & Co., Inc. 4-(Substituted phenyl thiazolyl)-3-hydroxy-3-pyrroline-2,5-diones
AU2005316536A1 (en) * 2004-12-17 2006-06-22 Mycosol, Inc. Thiazolium compounds and uses thereof
WO2007056340A2 (en) * 2005-11-08 2007-05-18 Mycosol, Inc. Disinfectant and antiseptic pyridinium and thiazolium compounds and methods of using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3390148A (en) * 1965-07-28 1968-06-25 Pfizer & Co C Novel thiazine and thiazoline anthelmintic agents
GB1244961A (en) * 1967-09-22 1971-09-02 Burroughs Wellcome Co Thiazole derivatives

Also Published As

Publication number Publication date
SE368709B (en) 1974-07-15
BE746998A (en) 1970-09-07
US3851060A (en) 1974-11-26
FR2096715A1 (en) 1972-02-25
DE2010490A1 (en) 1970-09-24
FR2096715B1 (en) 1974-02-01
NL7003246A (en) 1970-09-09
CH574958A5 (en) 1976-04-30
CH555857A (en) 1974-11-15
CA960667A (en) 1975-01-07

Similar Documents

Publication Publication Date Title
GB1222708A (en) Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
GB1409693A (en) Triazolobenzodiazepines
GB1437136A (en) Anti-inflammatory thiazole compounds compositions and methods for using same
GB1213056A (en) Aminoalkylthiocarboxylic acids and their use as photographic antifoggants
GB1456627A (en) Pyridobenzodiazepinones
GB1304174A (en)
GB1415471A (en) Phenylethylamine derivatives
GB1258797A (en)
GB1407856A (en) Anti-inflammatory thiazole compositions and methods for using same
GB1394757A (en) Lysino-calcium chloride
GB1347930A (en) Imidazolines and a proces for the preparation thereof
GB1244961A (en) Thiazole derivatives
GB1187071A (en) N-Amino-Substituted 4-Anilino-Pyridines
ES375495A1 (en) Ketones derived from -1-(2-hydroxyethyl)-piperazine
ES345690A1 (en) 2-aminomethyl benzofuran derivatives
ES412068A1 (en) Xylidides
ES392848A1 (en) Indenopyrrole derivatives
GB1384523A (en) Oxime derivatives and their preparation
GB1339010A (en) Tetrazolyl-anthraquinone derivatives
GB1244481A (en) Benzothiazine derivatives and the preparation thereof
GB1219254A (en) Sydnonimine derivatives
GB1437149A (en) Spiro-compounds and a process for their preparation
GB1279561A (en) Thiazolylacetic acid derivatives, methods of making them, and compositions containing them
GB1411782A (en) Piperidine derivatives
JPS523081A (en) Preparation of sulfonylpyridazionones

Legal Events

Date Code Title Description
416 Proceeding under section 16 patents act 1949
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee