GB1377339A - Method for producing deacetoxycephalosporin c - Google Patents
Method for producing deacetoxycephalosporin cInfo
- Publication number
- GB1377339A GB1377339A GB1838773A GB1838773A GB1377339A GB 1377339 A GB1377339 A GB 1377339A GB 1838773 A GB1838773 A GB 1838773A GB 1838773 A GB1838773 A GB 1838773A GB 1377339 A GB1377339 A GB 1377339A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nrrl
- desacetoxycephalosporin
- april
- cephalosporium
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NNQIJOYQWYKBOW-VMAXQDLPSA-N deacetoxycephalosporin-c Chemical compound S1CC(C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@H](N)C(O)=O)[C@H]12 NNQIJOYQWYKBOW-VMAXQDLPSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- NNQIJOYQWYKBOW-UHFFFAOYSA-N desacetoxycephalosphorin G Natural products S1CC(C)=C(C(O)=O)N2C(=O)C(NC(=O)CCCC(N)C(O)=O)C12 NNQIJOYQWYKBOW-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- 241001619326 Cephalosporium Species 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 241000135254 Cephalosporium sp. Species 0.000 abstract 1
- 241000018673 Emericellopsis sp. Species 0.000 abstract 1
- 241000908213 Metarhizium carneum Species 0.000 abstract 1
- 241001236817 Paecilomyces <Clavicipitaceae> Species 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 241000754833 Pochonia chlamydosporia Species 0.000 abstract 1
- 241000122799 Scopulariopsis Species 0.000 abstract 1
- 241000915973 Scopulariopsis sp. Species 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/06—Cephalosporin C; Derivatives thereof
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cephalosporin Compounds (AREA)
Abstract
1377339 Producing desacetoxycephalosporin C ELI LILLY & CO 17 April 1973 [26 April 1972 (4) 9 April 1973] 18387/73 Heading C2C Desacetoxycephalosporin C is produced by aerobically cultivating a desacetoxycephalosporin C- and penicillin N-CO-producing micro-organism of the genus Cephalosporium, Emeicellopsis, Scopulariopsis, Paecilomyces or Diheterospora in aqueous nutrient medium and then isolating desacetoxycephalosporin C from the resulting culture medium. The preferred organisms are Cephalosporium chrysogenum ATCC 14615, Cephalosporium sp. NRRL 5445, 5446, 5447, 5712, 5716, 5718, 5719, 5720, 5721, 5722, 5723, 5724 and 5725; Emericellopsis sp. NRRL 5446, 5447, 5713, 5714 and 5717; Scopulariopsis sp. NRRL 5715; Paecilomyces carneus NRRL 5711; and Diheterospora chlamydosporia NRRL 5728. The product is isolated by acidifying the whole culture broth to about pH 2, filtering off the mycelium and adsorbing the product on carbon followed by elution with aqueous acetone.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24766972A | 1972-04-26 | 1972-04-26 | |
| US24766772A | 1972-04-26 | 1972-04-26 | |
| US24760872A | 1972-04-26 | 1972-04-26 | |
| US24766872A | 1972-04-26 | 1972-04-26 | |
| US00348341A US3847742A (en) | 1972-04-26 | 1973-04-09 | Process for deacetoxycephalosporin c |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1377339A true GB1377339A (en) | 1974-12-11 |
Family
ID=27540254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1838773A Expired GB1377339A (en) | 1972-04-26 | 1973-04-17 | Method for producing deacetoxycephalosporin c |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5752840B2 (en) |
| AR (1) | AR197502A1 (en) |
| AU (1) | AU472455B2 (en) |
| CA (1) | CA985648A (en) |
| CH (1) | CH565246A5 (en) |
| DD (1) | DD103261A5 (en) |
| DE (1) | DE2320696A1 (en) |
| DK (1) | DK135326B (en) |
| FR (1) | FR2182136B1 (en) |
| GB (1) | GB1377339A (en) |
| IE (1) | IE37561B1 (en) |
| IL (1) | IL42050A (en) |
| NL (1) | NL7305881A (en) |
| PH (1) | PH13200A (en) |
| RO (1) | RO63439A (en) |
| SE (1) | SE388873B (en) |
| SU (1) | SU582772A3 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113234093A (en) * | 2021-04-13 | 2021-08-10 | 伊犁川宁生物技术股份有限公司 | 3-deacetoxy cephalosporin C sodium salt and preparation method thereof |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5421437B2 (en) * | 1973-10-08 | 1979-07-30 | ||
| JPS5417031B2 (en) * | 1973-06-16 | 1979-06-27 |
-
1973
- 1973-04-16 IL IL4205073A patent/IL42050A/en unknown
- 1973-04-17 GB GB1838773A patent/GB1377339A/en not_active Expired
- 1973-04-18 AU AU54688/73A patent/AU472455B2/en not_active Expired
- 1973-04-18 CA CA169,038A patent/CA985648A/en not_active Expired
- 1973-04-24 DE DE19732320696 patent/DE2320696A1/en active Pending
- 1973-04-25 CH CH589673A patent/CH565246A5/xx not_active IP Right Cessation
- 1973-04-25 DD DD17042973A patent/DD103261A5/xx unknown
- 1973-04-25 IE IE64573A patent/IE37561B1/en unknown
- 1973-04-25 DK DK225473A patent/DK135326B/en unknown
- 1973-04-25 SE SE7305770A patent/SE388873B/en unknown
- 1973-04-25 SU SU731920728A patent/SU582772A3/en active
- 1973-04-26 JP JP48047535A patent/JPS5752840B2/ja not_active Expired
- 1973-04-26 NL NL7305881A patent/NL7305881A/xx not_active Application Discontinuation
- 1973-04-26 AR AR24773373A patent/AR197502A1/en active
- 1973-04-26 PH PH14545A patent/PH13200A/en unknown
- 1973-04-26 RO RO7462773A patent/RO63439A/en unknown
- 1973-04-26 FR FR7315149A patent/FR2182136B1/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113234093A (en) * | 2021-04-13 | 2021-08-10 | 伊犁川宁生物技术股份有限公司 | 3-deacetoxy cephalosporin C sodium salt and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5752840B2 (en) | 1982-11-10 |
| DD103261A5 (en) | 1974-01-12 |
| CH565246A5 (en) | 1975-08-15 |
| IE37561L (en) | 1973-10-26 |
| DK135326B (en) | 1977-04-04 |
| DK135326C (en) | 1977-09-19 |
| DE2320696A1 (en) | 1973-11-15 |
| AU472455B2 (en) | 1976-05-27 |
| IL42050A (en) | 1976-08-31 |
| CA985648A (en) | 1976-03-16 |
| FR2182136A1 (en) | 1973-12-07 |
| AR197502A1 (en) | 1974-04-15 |
| AU5468873A (en) | 1974-10-24 |
| SU582772A3 (en) | 1977-11-30 |
| NL7305881A (en) | 1973-10-30 |
| JPS4947595A (en) | 1974-05-08 |
| FR2182136B1 (en) | 1975-08-22 |
| RO63439A (en) | 1978-08-15 |
| SE388873B (en) | 1976-10-18 |
| IE37561B1 (en) | 1977-08-17 |
| PH13200A (en) | 1980-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE44090L (en) | Antibiotic | |
| Erickson et al. | Penicillin acylase activity of Penicillium chrysogenum | |
| Cole et al. | 6-Aminopenicillanic acid II. Formation of 6-aminopenicillanic acid by Emericellopsis minima (Stolk) and related fungi | |
| DE3066026D1 (en) | A method for the production of antibiotic c-15003 p-3 | |
| ES475178A1 (en) | Method for producing antibiotic C-15003 P-3 | |
| ES373632A1 (en) | Process for the preparation of daunorubicin | |
| GB1157213A (en) | Process for the Manufacture of D-Lactic Acid and its Salts | |
| GB1376575A (en) | Process for the production of a saccharase inhibitor | |
| GB1454735A (en) | Lincomycin production | |
| AU3040884A (en) | Antibiotics produced by kibdelosporangium ardium shearer Gen. Nov., Sp. Nov. Atcc 39323 | |
| GB1377339A (en) | Method for producing deacetoxycephalosporin c | |
| IE40094L (en) | Process for producing deacetoxy-cephalosporin c | |
| ES412128A1 (en) | Antibiotic a-25822 and process for production thereof | |
| GB1433528A (en) | Method for producing deacetylcephalosporin c | |
| GB1474740A (en) | Production of deacetoxy-cephalosporin c | |
| GB1109362A (en) | Improvements in fermentation processes for the production of antibiotics from emericellopsis-cephalosporium fungi | |
| ES475179A1 (en) | Method for producing antibiotic C-15003 P-4 | |
| GB1331959A (en) | Process for producing 6-aminopenicillanic acid | |
| GB1111010A (en) | Process for the production of the antibiotic pleuromutilin | |
| GB1408158A (en) | Microbial beta-amylase and preparation thereof | |
| GB998195A (en) | Process for the production of an antibiotic | |
| GB1382316A (en) | Fermentation for producing an antibiotic | |
| IE39682B1 (en) | An improvement in the production of rifamycin b | |
| GB1318828A (en) | Process for the manufacture of zeaxanthin | |
| IE41079B1 (en) | Antibiotic a-28086 and process for production thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |