GB1274021A - The manufacture of medicaments of which the excipient comprises a mixture of saccharose and glucose - Google Patents
The manufacture of medicaments of which the excipient comprises a mixture of saccharose and glucoseInfo
- Publication number
- GB1274021A GB1274021A GB3338269A GB3338269A GB1274021A GB 1274021 A GB1274021 A GB 1274021A GB 3338269 A GB3338269 A GB 3338269A GB 3338269 A GB3338269 A GB 3338269A GB 1274021 A GB1274021 A GB 1274021A
- Authority
- GB
- United Kingdom
- Prior art keywords
- medicaments
- glucose
- saccharose
- manufacture
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 title abstract 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 title abstract 2
- 229930006000 Sucrose Natural products 0.000 title abstract 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 title abstract 2
- 239000008103 glucose Substances 0.000 title abstract 2
- 235000013681 dietary sucrose Nutrition 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000546 pharmaceutical excipient Substances 0.000 title 1
- 229960004793 sucrose Drugs 0.000 title 1
- 239000011575 calcium Substances 0.000 abstract 3
- 239000011777 magnesium Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 abstract 1
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 abstract 1
- 235000012411 boiled sweets Nutrition 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 235000009508 confectionery Nutrition 0.000 abstract 1
- 229940050410 gluconate Drugs 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 159000000003 magnesium salts Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,274,021. Medicament bases. SOC D'EXPLOITATION DU LABORATOIRE PLE. 2 July, 1969, No. 33382/69. Heading A5B. [Also in Division A2] A hard candy or "boiled sweet" type base for medicaments is prepared by adding a sparingly soluble calcium salt and a magnesium salt (e.g. Ca or Mg gluconate, Mg glycerophosphate) to an aqueous syrup containing glucose and sucrose to which the medicament is added and which is then heated to no more than 120‹C to remove sufficient of the water. The solubility of the Ca salt should be no more than 3 parts by weight in 100 parts of water at 15‹C, 0.35 to 0.70g (calculated as Ca) being a suitable quantity for 100g of finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3338269A GB1274021A (en) | 1969-07-02 | 1969-07-02 | The manufacture of medicaments of which the excipient comprises a mixture of saccharose and glucose |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3338269A GB1274021A (en) | 1969-07-02 | 1969-07-02 | The manufacture of medicaments of which the excipient comprises a mixture of saccharose and glucose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1274021A true GB1274021A (en) | 1972-05-10 |
Family
ID=10352217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3338269A Expired GB1274021A (en) | 1969-07-02 | 1969-07-02 | The manufacture of medicaments of which the excipient comprises a mixture of saccharose and glucose |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1274021A (en) |
-
1969
- 1969-07-02 GB GB3338269A patent/GB1274021A/en not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |