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GB1263483A - Sample injector for use in liquid chromatography - Google Patents

Sample injector for use in liquid chromatography

Info

Publication number
GB1263483A
GB1263483A GB26916/70A GB2691670A GB1263483A GB 1263483 A GB1263483 A GB 1263483A GB 26916/70 A GB26916/70 A GB 26916/70A GB 2691670 A GB2691670 A GB 2691670A GB 1263483 A GB1263483 A GB 1263483A
Authority
GB
United Kingdom
Prior art keywords
bores
liquid chromatography
plate
sample
ports
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB26916/70A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Publication of GB1263483A publication Critical patent/GB1263483A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/468—Flow patterns using more than one column involving switching between different column configurations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/22—Injection in high pressure liquid systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel

Landscapes

  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Multiple-Way Valves (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

1,263,483. Automatic liquid chromatography apparatus. BECKMAN INSTRUMENTS Inc. 26 March, 1969 [2 April, 1968], No. 26916/70. Divided out of 1,263,481. Heading B1X. A sampling valve suitable for use in the high pressure automatic liquid chromatography systems described in Specifications 1,263,481 and 1,263,482, comprises stationary plate 75 and rotary plate 76. Rotary plate 76 comprises bores 77-80 (Fig. 11), bores 77, 78 being connected through sample-metering chamber 82 (Figs. 7, 8) while bores 79, 80 are directly connected by a by-pass bore 81 (Figs. 8, 11). Each of the ports of the bores is countersunk to allow resilient shear type seals to be positioned around the port. Stationary plate 75 (Fig. 9) also comprises ports 100, 101 to allow inert gas, e.g. nitrogen at 25 psig, to be passed between the plates 75, 76 to flush and cleanse the plate surfaces of sample or eluent.
GB26916/70A 1968-04-02 1969-03-26 Sample injector for use in liquid chromatography Expired GB1263483A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71816668A 1968-04-02 1968-04-02

Publications (1)

Publication Number Publication Date
GB1263483A true GB1263483A (en) 1972-02-09

Family

ID=24885079

Family Applications (3)

Application Number Title Priority Date Filing Date
GB26916/70A Expired GB1263483A (en) 1968-04-02 1969-03-26 Sample injector for use in liquid chromatography
GB26915/70A Expired GB1263482A (en) 1968-04-02 1969-03-26 Sample injector for use in liquid chromatography
GB05815/69A Expired GB1263481A (en) 1968-04-02 1969-03-26 Sample injector for use in liquid chromatography

Family Applications After (2)

Application Number Title Priority Date Filing Date
GB26915/70A Expired GB1263482A (en) 1968-04-02 1969-03-26 Sample injector for use in liquid chromatography
GB05815/69A Expired GB1263481A (en) 1968-04-02 1969-03-26 Sample injector for use in liquid chromatography

Country Status (4)

Country Link
US (1) US3504799A (en)
JP (1) JPS5020877B1 (en)
DE (1) DE1915113A1 (en)
GB (3) GB1263483A (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1441462A (en) * 1973-02-14 1976-06-30 Univ Edinburgh University Cour Method and apapratus for liquid chromotography
US3926809A (en) * 1973-10-10 1975-12-16 Roosevelt J Jones Multi-column fractionator
US3830369A (en) * 1973-12-11 1974-08-20 E Pfadenhauer High pressure gradient chamber for liquid chromatography
JPS5630500B2 (en) * 1974-02-27 1981-07-15
DE2418509C3 (en) * 1974-04-17 1978-04-27 Sartorius-Membranfilter Gmbh, 3400 Goettingen Device for the semi-automatic simultaneous column chromatographic separation of a large number of sample solutions
JPS5330390A (en) * 1976-09-02 1978-03-22 Nippon Bunko Kogyo Kk Liquid chromatograph
JPS54114991U (en) * 1978-02-01 1979-08-13
JPS55144543A (en) * 1979-04-28 1980-11-11 Japan Spectroscopic Co Device for introducing trace specimen in chromaograph separator
US4444066A (en) * 1981-06-29 1984-04-24 Beckman Instruments, Inc. High pressure sample injector valve
US4926702A (en) * 1987-09-18 1990-05-22 Beckman Instruments, Inc. Sample presence detector for automatic sample injector
US4957008A (en) * 1988-12-28 1990-09-18 Coulter Electronics, Inc. Fluid sampling and transfer valve assembly
US5443734A (en) * 1990-03-05 1995-08-22 Applied Separations, Inc. Programmable solid phase extraction and elution device
US6635173B2 (en) 2000-12-28 2003-10-21 Cohesive Technologies, Inc. Multi column chromatography system
US6672336B2 (en) 2001-11-28 2004-01-06 Rheodyne, Lp Dual random access, three-way rotary valve apparatus
US7588683B2 (en) * 2005-08-03 2009-09-15 Agilent Technologies, Inc. Column for liquid chromatography with adjustable compression
CA2683944A1 (en) * 2007-05-15 2008-11-20 Ge Healthcare Bio-Sciences Ab Flow distributing valve
JP2011141120A (en) * 2008-10-07 2011-07-21 Arkray Inc Liquid chromatography device and liquid chromatography
JP6035603B2 (en) 2012-12-19 2016-11-30 株式会社日立ハイテクノロジーズ Sample introduction device
US9404900B2 (en) 2012-12-21 2016-08-02 Thermo Finnigan Llc System for analysis of phase-I and phase-II metabolites and parent compounds without hydrolysis
US20190265206A1 (en) * 2015-10-20 2019-08-29 Waters Technologies Corporation Systems, methods and devices for cross-stream injection chromatography
EP3365672B1 (en) * 2015-10-20 2021-12-01 Waters Technologies Corporation Systems, methods and devices for decreasing solubility problems in chromatography
WO2018128836A1 (en) 2017-01-06 2018-07-12 Waters Technologies Corporation Modifier stream elution of trap column for multidimensional compressible fluid-based chromatography
JP6895819B2 (en) * 2017-06-26 2021-06-30 アークレイ株式会社 Liquid chromatography equipment
US10527192B2 (en) 2018-02-15 2020-01-07 Talis Biomedical Corporation Rotary valve
CN111323289B (en) * 2018-12-17 2024-08-20 中核建中核燃料元件有限公司 Automatic machine of etching that wipes of metallographic specimen
US11008627B2 (en) 2019-08-15 2021-05-18 Talis Biomedical Corporation Diagnostic system
CN111879955B (en) * 2020-07-30 2022-04-19 中国科学院植物研究所 Automatic sample injector

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3249403A (en) * 1962-11-02 1966-05-03 Beckman Instruments Inc Liquid sample reactor and evolved gas detector
US3223123A (en) * 1963-05-27 1965-12-14 Sun Oil Co Multifunction valve for chromatography
DE1598205B1 (en) * 1964-04-13 1971-05-19 Ceskoslovenska Akademie Ved DEVICE FOR CHROMATOGRAPHY OF AMINO ACIDS AND MIXTURES CONTAINING THE SAME

Also Published As

Publication number Publication date
JPS5020877B1 (en) 1975-07-18
GB1263481A (en) 1972-02-09
DE1915113A1 (en) 1969-10-23
GB1263482A (en) 1972-02-09
US3504799A (en) 1970-04-07

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