GB1253328A - PURIFICATION OF gamma GLOBULIN - Google Patents
PURIFICATION OF gamma GLOBULINInfo
- Publication number
- GB1253328A GB1253328A GB03046/70A GB1304670A GB1253328A GB 1253328 A GB1253328 A GB 1253328A GB 03046/70 A GB03046/70 A GB 03046/70A GB 1304670 A GB1304670 A GB 1304670A GB 1253328 A GB1253328 A GB 1253328A
- Authority
- GB
- United Kingdom
- Prior art keywords
- globulin
- solution
- recovered
- plasma
- serum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010074605 gamma-Globulins Proteins 0.000 title abstract 6
- 238000000746 purification Methods 0.000 title abstract 2
- 239000000243 solution Substances 0.000 abstract 6
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 4
- 210000002381 plasma Anatomy 0.000 abstract 4
- 210000002966 serum Anatomy 0.000 abstract 4
- IYLLULUTZPKQBW-UHFFFAOYSA-N Acrinol Chemical compound CC(O)C(O)=O.C1=C(N)C=CC2=C(N)C3=CC(OCC)=CC=C3N=C21 IYLLULUTZPKQBW-UHFFFAOYSA-N 0.000 abstract 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 3
- 239000008363 phosphate buffer Substances 0.000 abstract 3
- 239000000741 silica gel Substances 0.000 abstract 3
- 229910002027 silica gel Inorganic materials 0.000 abstract 3
- JVIPLYCGEZUBIO-UHFFFAOYSA-N 2-(4-fluorophenyl)-1,3-dioxoisoindole-5-carboxylic acid Chemical compound O=C1C2=CC(C(=O)O)=CC=C2C(=O)N1C1=CC=C(F)C=C1 JVIPLYCGEZUBIO-UHFFFAOYSA-N 0.000 abstract 2
- 229920001425 Diethylaminoethyl cellulose Polymers 0.000 abstract 2
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 abstract 2
- 239000003463 adsorbent Substances 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- FSBVERYRVPGNGG-UHFFFAOYSA-N dimagnesium dioxido-bis[[oxido(oxo)silyl]oxy]silane hydrate Chemical compound O.[Mg+2].[Mg+2].[O-][Si](=O)O[Si]([O-])([O-])O[Si]([O-])=O FSBVERYRVPGNGG-UHFFFAOYSA-N 0.000 abstract 2
- 210000003743 erythrocyte Anatomy 0.000 abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
- 239000000391 magnesium silicate Substances 0.000 abstract 2
- 239000011707 mineral Substances 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- UNYSKUBLZGJSLV-UHFFFAOYSA-L calcium;1,3,5,2,4,6$l^{2}-trioxadisilaluminane 2,4-dioxide;dihydroxide;hexahydrate Chemical compound O.O.O.O.O.O.[OH-].[OH-].[Ca+2].O=[Si]1O[Al]O[Si](=O)O1.O=[Si]1O[Al]O[Si](=O)O1 UNYSKUBLZGJSLV-UHFFFAOYSA-L 0.000 abstract 1
- FGZBFIYFJUAETR-UHFFFAOYSA-N calcium;magnesium;silicate Chemical compound [Mg+2].[Ca+2].[O-][Si]([O-])([O-])[O-] FGZBFIYFJUAETR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052676 chabazite Inorganic materials 0.000 abstract 1
- 229910052677 heulandite Inorganic materials 0.000 abstract 1
- 210000003563 lymphoid tissue Anatomy 0.000 abstract 1
- 229910052919 magnesium silicate Inorganic materials 0.000 abstract 1
- 235000019792 magnesium silicate Nutrition 0.000 abstract 1
- 229910000386 magnesium trisilicate Inorganic materials 0.000 abstract 1
- 235000019793 magnesium trisilicate Nutrition 0.000 abstract 1
- 229940099273 magnesium trisilicate Drugs 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 229910052678 stilbite Inorganic materials 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81240469A | 1969-04-01 | 1969-04-01 | |
| US1622570A | 1970-03-03 | 1970-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1253328A true GB1253328A (en) | 1971-11-10 |
Family
ID=26688328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB03046/70A Expired GB1253328A (en) | 1969-04-01 | 1970-03-18 | PURIFICATION OF gamma GLOBULIN |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5515444B1 (de) |
| BE (1) | BE748326A (de) |
| CH (1) | CH548776A (de) |
| DE (1) | DE2014957C2 (de) |
| DK (1) | DK128147B (de) |
| FR (1) | FR2038106B1 (de) |
| GB (1) | GB1253328A (de) |
| IL (1) | IL34079A (de) |
| NL (1) | NL164286C (de) |
| SE (1) | SE386824B (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2001325A (en) * | 1977-07-19 | 1979-01-31 | Green Cross Corp | Gamma globulin preparation |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2837168A1 (de) * | 1978-08-25 | 1980-03-06 | Blutspendedienst Dt Rote Kreuz | Verfahren zur herstellung einer fuer die intravenoese anwendung geeigneten immunglobulinloesung |
| US4315851A (en) | 1978-12-29 | 1982-02-16 | Kureha Kagaku Kogyo Kabushiki Kaisha | Pharmaceutical composition having antitumor activity |
| MXPA05007378A (es) * | 2003-01-09 | 2005-11-23 | Genentech Inc | Purificacion de polipeptidos. |
| KR20150115745A (ko) * | 2013-02-06 | 2015-10-14 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 단백질 제제로부터 응집체 함량을 감소시키는 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3382227A (en) * | 1967-01-30 | 1968-05-07 | Pentex Inc | Blood protein fractionation employing 2-ethoxy-6, 9-diamino-acridine-lactate |
| US3449316A (en) * | 1967-03-03 | 1969-06-10 | American Cyanamid Co | Process for the purification of gamma globulin employing bentonite |
-
1970
- 1970-03-16 IL IL34079A patent/IL34079A/xx unknown
- 1970-03-18 GB GB03046/70A patent/GB1253328A/en not_active Expired
- 1970-03-19 DK DK140870AA patent/DK128147B/da not_active IP Right Cessation
- 1970-03-26 NL NL7004373.A patent/NL164286C/xx not_active IP Right Cessation
- 1970-03-28 DE DE2014957A patent/DE2014957C2/de not_active Expired
- 1970-03-31 SE SE7004357A patent/SE386824B/xx unknown
- 1970-03-31 FR FR7011475A patent/FR2038106B1/fr not_active Expired
- 1970-04-01 JP JP2709470A patent/JPS5515444B1/ja active Pending
- 1970-04-01 CH CH480770A patent/CH548776A/de not_active IP Right Cessation
- 1970-04-01 BE BE748326D patent/BE748326A/xx not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2001325A (en) * | 1977-07-19 | 1979-01-31 | Green Cross Corp | Gamma globulin preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7004373A (de) | 1970-10-05 |
| IL34079A0 (en) | 1970-06-17 |
| FR2038106B1 (de) | 1974-02-01 |
| BE748326A (fr) | 1970-10-01 |
| NL164286B (nl) | 1980-07-15 |
| IL34079A (en) | 1973-02-28 |
| CH548776A (de) | 1974-05-15 |
| JPS5515444B1 (de) | 1980-04-23 |
| SE386824B (sv) | 1976-08-23 |
| FR2038106A1 (de) | 1971-01-08 |
| DE2014957C2 (de) | 1982-01-28 |
| DE2014957A1 (de) | 1970-11-05 |
| DK128147B (da) | 1974-03-11 |
| NL164286C (nl) | 1980-12-15 |
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