GB1250219A - - Google Patents
Info
- Publication number
- GB1250219A GB1250219A GB1250219DA GB1250219A GB 1250219 A GB1250219 A GB 1250219A GB 1250219D A GB1250219D A GB 1250219DA GB 1250219 A GB1250219 A GB 1250219A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compositions
- derivatives
- antibacterial
- hydroxy
- natural
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000463 material Substances 0.000 abstract 3
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000011368 organic material Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 229920002994 synthetic fiber Polymers 0.000 abstract 2
- -1 tinctures Substances 0.000 abstract 2
- 150000000183 1,3-benzoxazoles Chemical class 0.000 abstract 1
- ASSKVPFEZFQQNQ-UHFFFAOYSA-N 2-benzoxazolinone Chemical class C1=CC=C2OC(O)=NC2=C1 ASSKVPFEZFQQNQ-UHFFFAOYSA-N 0.000 abstract 1
- 241001323490 Colias gigantea Species 0.000 abstract 1
- 101000993347 Gallus gallus Ciliary neurotrophic factor Proteins 0.000 abstract 1
- 239000004098 Tetracycline Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 230000001572 anti-trichomonad Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 229940027988 antiseptic and disinfectant nitrofuran derivative Drugs 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- DKVNPHBNOWQYFE-UHFFFAOYSA-N carbamodithioic acid Chemical class NC(S)=S DKVNPHBNOWQYFE-UHFFFAOYSA-N 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 229960005091 chloramphenicol Drugs 0.000 abstract 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 abstract 1
- 230000002192 coccidiostatic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000007937 lozenge Substances 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- IAIWVQXQOWNYOU-FPYGCLRLSA-N nitrofural Chemical class NC(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 IAIWVQXQOWNYOU-FPYGCLRLSA-N 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical class C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 229960002180 tetracycline Drugs 0.000 abstract 1
- 229930101283 tetracycline Natural products 0.000 abstract 1
- 235000019364 tetracycline Nutrition 0.000 abstract 1
- 150000003522 tetracyclines Chemical class 0.000 abstract 1
- 239000004753 textile Substances 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
- 230000000654 trypanocidal effect Effects 0.000 abstract 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Dentistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1,250,219. Antibacterial &c. compositions. J. R. GEIGY A.G. 28 Jan., 1970 [6 Dec., 1968], No. 57941/68. Addition to 1,108,397. Heading A5B and A5E. [Also in Division C2] Antimicrobial nitrofuran derivatives of formula I: in which each of R<SP>4</SP>, R<SP>5</SP> and R<SP>6</SP> is a C 1-5 alkyl group optionally carrying one or more halogen, hydroxy or C 1-5 alkoxy substituents, a C 3-4 alkenyl group or a cycloalkyl group, or one or two of R<SP>4</SP>, R<SP>5</SP> and R<SP>6</SP> may be hydrogen, may be mixed with pharmaceutically acceptable carriers to form pharmaceutical compositions, or used to treat an organic material susceptible to bacterial or other microbial attack to protect the material from such attack. The organic material may be a natural or synthetic polymeric material, a proteinaceous or carbohydrate substance, or a natural or synthetic fibre or textile material formed therefrom. The pharmaceutical compositions have antibacterial, antifungal, antiviral, anthelmintic, coccidiostatic, antitrichomonal, trypanocidal and growthpromoting activity and may be in the form of ointments, powders, tinctures, solutions, emulsions, gargles, tablets, lozenges, dragees and capsules. The compositions may also contain other active ingredients such as 8-quinolinol derivatives, sulpha drugs, chloramphenicol or tetracycline or other antibiotics, halogenated salicylanilides, carbanilides, benzoxazoles or benzoxazolones, polychloro-hydroxy-diphenylmethanes, halogenhydroxydiphenyl sulphides or ethers, quaternary ammonium compounds or dithiocarbamic acid derivatives. Specific compounds are named. Carriers which themselves have pharmaceutical activity, e.g. sulphur and zinc stearate, can be used.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5794168 | 1968-12-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1250219A true GB1250219A (en) | 1971-10-20 |
Family
ID=10480418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1250219D Expired GB1250219A (en) | 1968-12-06 | 1968-12-06 |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1250219A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003013517A1 (en) * | 2001-08-06 | 2003-02-20 | Pharmacia Italia S.P.A. | Aminoisoxazole derivatives active as kinase inhibitors |
| US8388991B2 (en) | 2009-05-01 | 2013-03-05 | Chattem, Inc. | Moisturizing antimicrobial composition |
-
1968
- 1968-12-06 GB GB1250219D patent/GB1250219A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003013517A1 (en) * | 2001-08-06 | 2003-02-20 | Pharmacia Italia S.P.A. | Aminoisoxazole derivatives active as kinase inhibitors |
| US8388991B2 (en) | 2009-05-01 | 2013-03-05 | Chattem, Inc. | Moisturizing antimicrobial composition |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |