GB1188364A - Quinoline Derivatives - Google Patents
Quinoline DerivativesInfo
- Publication number
- GB1188364A GB1188364A GB20400/67A GB2040067A GB1188364A GB 1188364 A GB1188364 A GB 1188364A GB 20400/67 A GB20400/67 A GB 20400/67A GB 2040067 A GB2040067 A GB 2040067A GB 1188364 A GB1188364 A GB 1188364A
- Authority
- GB
- United Kingdom
- Prior art keywords
- saturated
- group
- unsaturated
- coccidiosis
- prevention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 3
- 208000003495 Coccidiosis Diseases 0.000 abstract 2
- 206010023076 Isosporiasis Diseases 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- GFGSZUNNBQXGMK-UHFFFAOYSA-N 2-chloro-4-nitrobenzamide Chemical compound NC(=O)C1=CC=C([N+]([O-])=O)C=C1Cl GFGSZUNNBQXGMK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- NHZLNPMOSADWGC-UHFFFAOYSA-N 4-amino-N-(2-quinoxalinyl)benzenesulfonamide Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=CN=C(C=CC=C2)C2=N1 NHZLNPMOSADWGC-UHFFFAOYSA-N 0.000 abstract 1
- 241000287828 Gallus gallus Species 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 230000001165 anti-coccidial effect Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 235000013330 chicken meat Nutrition 0.000 abstract 1
- 239000003224 coccidiostatic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229960001625 furazolidone Drugs 0.000 abstract 1
- PLHJDBGFXBMTGZ-WEVVVXLNSA-N furazolidone Chemical compound O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)OCC1 PLHJDBGFXBMTGZ-WEVVVXLNSA-N 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- IAIWVQXQOWNYOU-FPYGCLRLSA-N nitrofural Chemical compound NC(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 IAIWVQXQOWNYOU-FPYGCLRLSA-N 0.000 abstract 1
- 229960001907 nitrofurazone Drugs 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 244000144977 poultry Species 0.000 abstract 1
- 235000013594 poultry meat Nutrition 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- NKFLEFWUYAUDJV-UHFFFAOYSA-N pyridine-3-sulfonamide Chemical compound NS(=O)(=O)C1=CC=CN=C1 NKFLEFWUYAUDJV-UHFFFAOYSA-N 0.000 abstract 1
- XMVJITFPVVRMHC-UHFFFAOYSA-N roxarsone Chemical compound OC1=CC=C([As](O)(O)=O)C=C1[N+]([O-])=O XMVJITFPVVRMHC-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,188,364. Anticoccidial compositions. MAY ' & BAKER Ltd. 1 May, 1968 [2 May, 1967], No. 20400/67. Heading A5B. [Also in Division C2]. Pharmaceutical compositions having use in the prevention of coccidiosis in chickens and anti-viral activity and containing compounds of the general formula: wherein R' is a saturated or unsaturated straight chain aliphatic group having 7 to 11 carbon atoms, R 1 , is a saturated or unsaturated straight or branched chain aliphatic group having 1 to 4 carbon atoms, R 2 , is methyl, ethyl, isopropyl, n-propyl, or allyl group, at least one of R', R 1 , and R 2 , being an unsaturated group as specified above, and R 3 is hydrogen or a saturated or unsaturated carboxylic acyl group, and, when R 3 is hydrogen, salts thereof are administered orally or parenterally in association with a physioligically innocuous carrier and/or physiologically innocuous wetting and/or dispersing agents. The compositions suitable for the prevention of coccidiosis may also contain one or more additional prophylactic or therapeutic agents, e.g. anti-bacterial agents such as furazolidone, or coccidiostats, such as 2-chloro-4- nitrobenzamide, pyridine-3-sulphonamide, nitrofurazone or sulphaquinoxaline. Also they may contain other substances known to be useful in promoting the growth of poultry or their egg production for example, 4-hydroxy- 3-nitrophenylarsonic acid and antibiotics such as penicillin and penicillin derivatives.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB20400/67A GB1188364A (en) | 1967-05-02 | 1967-05-02 | Quinoline Derivatives |
| FR1584259D FR1584259A (en) | 1967-05-02 | 1968-04-30 | |
| IT1596468A IT1056722B (en) | 1967-05-02 | 1968-04-30 | HETEROCELIC COMPOUNDS |
| FR150138A FR7611M (en) | 1967-05-02 | 1968-04-30 | |
| ES353413A ES353413A1 (en) | 1967-05-02 | 1968-05-02 | Quinoline Derivatives |
| CH651068A CH487158A (en) | 1967-05-02 | 1968-05-02 | Process for the preparation of novel quinoline carboxylic acid derivatives |
| DE19681770317 DE1770317A1 (en) | 1967-05-02 | 1968-05-02 | New quinoline derivatives and processes for their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB20400/67A GB1188364A (en) | 1967-05-02 | 1967-05-02 | Quinoline Derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1188364A true GB1188364A (en) | 1970-04-15 |
Family
ID=10145349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB20400/67A Expired GB1188364A (en) | 1967-05-02 | 1967-05-02 | Quinoline Derivatives |
Country Status (6)
| Country | Link |
|---|---|
| CH (1) | CH487158A (en) |
| DE (1) | DE1770317A1 (en) |
| ES (1) | ES353413A1 (en) |
| FR (2) | FR1584259A (en) |
| GB (1) | GB1188364A (en) |
| IT (1) | IT1056722B (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2200109A (en) * | 1986-11-28 | 1988-07-27 | Orion Yhtymae Oy | Catechol derivatives |
| US5001152A (en) * | 1987-12-24 | 1991-03-19 | Orion Corporation Ltd. | Use of catechol-O-methyl transferase (COMT) inhibitors and their physiologically acceptable salts for ulcer treatment |
| EP0456442A1 (en) * | 1990-05-09 | 1991-11-13 | Zeneca Limited | Quinoline derivatives, process for their preparation and their use as medicaments |
| US5112861A (en) * | 1986-11-28 | 1992-05-12 | Orion-Yhtyma Oy | Method of treating parkinson's disease using pentanedione derivatives |
| US5283352A (en) * | 1986-11-28 | 1994-02-01 | Orion-Yhtyma Oy | Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same |
| US5489614A (en) * | 1987-11-27 | 1996-02-06 | Orion-Yhtyma Oy | Catechol derivatives, their physiologically acceptable salts, esters and use |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH590236A5 (en) * | 1973-07-03 | 1977-07-29 | Ciba Geigy Ag |
-
1967
- 1967-05-02 GB GB20400/67A patent/GB1188364A/en not_active Expired
-
1968
- 1968-04-30 FR FR1584259D patent/FR1584259A/fr not_active Expired
- 1968-04-30 IT IT1596468A patent/IT1056722B/en active
- 1968-04-30 FR FR150138A patent/FR7611M/fr not_active Expired
- 1968-05-02 DE DE19681770317 patent/DE1770317A1/en active Pending
- 1968-05-02 ES ES353413A patent/ES353413A1/en not_active Expired
- 1968-05-02 CH CH651068A patent/CH487158A/en not_active IP Right Cessation
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2200109A (en) * | 1986-11-28 | 1988-07-27 | Orion Yhtymae Oy | Catechol derivatives |
| US4963590A (en) * | 1986-11-28 | 1990-10-16 | Orion-Yhtyma Oy | Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same |
| GB2200109B (en) * | 1986-11-28 | 1991-07-03 | Orion Yhtymae Oy | New pharmacologically active compounds, methods for the preparation thereof and compositions containing the same |
| US5112861A (en) * | 1986-11-28 | 1992-05-12 | Orion-Yhtyma Oy | Method of treating parkinson's disease using pentanedione derivatives |
| US5283352A (en) * | 1986-11-28 | 1994-02-01 | Orion-Yhtyma Oy | Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same |
| US5446194A (en) * | 1986-11-28 | 1995-08-29 | Orion-Yhtyma Oy | Pharmacologically active catechol derivatives |
| LT3770B (en) | 1986-11-28 | 1996-03-25 | Orion Yhtymae Oy | Catehol derivatives,methods for their preparation and pharmaceutical compositions containing them |
| US5489614A (en) * | 1987-11-27 | 1996-02-06 | Orion-Yhtyma Oy | Catechol derivatives, their physiologically acceptable salts, esters and use |
| US5001152A (en) * | 1987-12-24 | 1991-03-19 | Orion Corporation Ltd. | Use of catechol-O-methyl transferase (COMT) inhibitors and their physiologically acceptable salts for ulcer treatment |
| EP0456442A1 (en) * | 1990-05-09 | 1991-11-13 | Zeneca Limited | Quinoline derivatives, process for their preparation and their use as medicaments |
| US5369114A (en) * | 1990-05-09 | 1994-11-29 | Imperial Chemical Industries Plc | Biphenylene branched alkyleneoxy quinolines |
Also Published As
| Publication number | Publication date |
|---|---|
| IT1056722B (en) | 1982-02-20 |
| FR7611M (en) | 1970-01-19 |
| DE1770317A1 (en) | 1971-10-07 |
| FR1584259A (en) | 1969-12-19 |
| ES353413A1 (en) | 1970-01-16 |
| CH487158A (en) | 1970-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY102919A (en) | Pleuromutilin derivatives process for their preparation and their use. | |
| GB1334138A (en) | Immunological adjuvatns | |
| GB1188364A (en) | Quinoline Derivatives | |
| GB1142066A (en) | New diphenyl-ureas and process for preparing them | |
| GB1153366A (en) | Substituted Benzoic Acid Lactones having Estrogenic Properties | |
| GB1256723A (en) | ||
| GB1188365A (en) | Quinoline Derivatives | |
| GB1168801A (en) | Quinoline Derivatives | |
| GB1322112A (en) | 3,4,5-trimethoxybenzoic acid derivatives and their uses | |
| GB1252286A (en) | ||
| GB1314952A (en) | 3,4,5-trialkoxy-benzoic acid derivatives and their uses | |
| GB1155529A (en) | Imidazole derivatives, their Preparation and Compositions containing them | |
| SE8701592D0 (en) | A PHARMACEUTICAL COMPOSITION COMPRISING AND ORGANIC ZINC COMPLEX AND A PROCESS FOR PREPARING THE ACTIVE SUBSTANCE | |
| GB1126860A (en) | Novel 4-substituted-7- and 8-chloroquinolines and a process for the preparation thereof | |
| GB1203430A (en) | Heterocyclic spiro compounds | |
| GB1152637A (en) | Veterinary Compositions | |
| GB1172841A (en) | 4-Acyloxy Quinoline Derivatives, Process for their Manufacture, and their use as Coccidiostats | |
| GB1274282A (en) | Benzohydroxamic acid and derivatives and compositions containing them | |
| GB1264197A (en) | ||
| GB1470289A (en) | Aminomethyl-arylmethylpenicillin derivatives | |
| GB1168302A (en) | Aluminium N-Acetylglycinate and Pharmaceutical Compositions containing the same | |
| GB1173636A (en) | Alkyl Phenylpiperazinylalkylcarbamates | |
| GB1342643A (en) | Thioacetanilide derivatives | |
| GB1464082A (en) | Pharmaceutical 'ompositions containing benzylamines | |
| GB1313838A (en) | 3,4,5-trialkoxybenzoic acid derivatives and their uses |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |