GB1184027A - New Dibenzo-Oxepine Derivatives and their preparation - Google Patents
New Dibenzo-Oxepine Derivatives and their preparationInfo
- Publication number
- GB1184027A GB1184027A GB3937068A GB3937068A GB1184027A GB 1184027 A GB1184027 A GB 1184027A GB 3937068 A GB3937068 A GB 3937068A GB 3937068 A GB3937068 A GB 3937068A GB 1184027 A GB1184027 A GB 1184027A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dibenzo
- oxepine
- hydroxy
- alkyl
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- QQQCGYCZORNOOS-UHFFFAOYSA-N benzo[b][1]benzoxepine Chemical class C1=CC2=CC=CC=C2OC2=CC=CC=C21 QQQCGYCZORNOOS-UHFFFAOYSA-N 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- WVDDGKGOMKODPV-UHFFFAOYSA-N hydroxymethyl benzene Natural products OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 2
- ATYBXHSAIOKLMG-UHFFFAOYSA-N oxepin Chemical compound O1C=CC=CC=C1 ATYBXHSAIOKLMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- WXPHCEXUADBYQI-UHFFFAOYSA-N 1-chloro-4-[2-(chloromethyl)phenoxy]benzene Chemical compound ClCC1=CC=CC=C1OC1=CC=C(Cl)C=C1 WXPHCEXUADBYQI-UHFFFAOYSA-N 0.000 abstract 1
- -1 2 - (4 - chlorophenoxy) benzyl Chemical group 0.000 abstract 1
- ALMJMOPIBISVHZ-UHFFFAOYSA-N 2-[2-(4-chlorophenoxy)phenyl]acetic acid Chemical compound OC(=O)CC1=CC=CC=C1OC1=CC=C(Cl)C=C1 ALMJMOPIBISVHZ-UHFFFAOYSA-N 0.000 abstract 1
- MBXFDCKHEJYOIP-UHFFFAOYSA-N 3-chloro-5-(1-methylpiperidin-4-yl)-6H-benzo[b][1]benzoxepin-5-ol Chemical compound ClC1=CC2=C(OC3=C(CC2(C2CCN(CC2)C)O)C=CC=C3)C=C1 MBXFDCKHEJYOIP-UHFFFAOYSA-N 0.000 abstract 1
- YIWBWLDIASAGSQ-UHFFFAOYSA-N 3-chloro-5-pyridin-4-yl-6H-benzo[b][1]benzoxepin-5-ol Chemical compound ClC1=CC2=C(OC3=C(CC2(C2=CC=NC=C2)O)C=CC=C3)C=C1 YIWBWLDIASAGSQ-UHFFFAOYSA-N 0.000 abstract 1
- MFJXRFHFNGOBKY-UHFFFAOYSA-N 3-chloro-6h-benzo[b][1]benzoxepin-5-one Chemical compound C1C(=O)C2=CC(Cl)=CC=C2OC2=CC=CC=C21 MFJXRFHFNGOBKY-UHFFFAOYSA-N 0.000 abstract 1
- UUHVEYXVVFZERY-UHFFFAOYSA-M 4-(3-chlorobenzo[b][1]benzoxepin-5-yl)-1-methylpyridin-1-ium bromide Chemical compound [Br-].ClC1=CC2=C(OC3=C(C=C2C2=CC=[N+](C=C2)C)C=CC=C3)C=C1 UUHVEYXVVFZERY-UHFFFAOYSA-M 0.000 abstract 1
- UVINXPBAUJMOAW-UHFFFAOYSA-N 4-(3-chlorobenzo[b][1]benzoxepin-5-yl)pyridine Chemical compound ClC1=CC2=C(OC3=C(C=C2C2=CC=NC=C2)C=CC=C3)C=C1 UVINXPBAUJMOAW-UHFFFAOYSA-N 0.000 abstract 1
- ZPNRYCUYELCCKN-UHFFFAOYSA-N 4-benzo[b][1]benzoxepin-5-ylpyridine Chemical compound N1=CC=C(C=C1)C1=CC2=C(OC3=C1C=CC=C3)C=CC=C2 ZPNRYCUYELCCKN-UHFFFAOYSA-N 0.000 abstract 1
- LHPPMPJEXNAURE-UHFFFAOYSA-N 5-(1-methylpiperidin-4-yl)-6H-benzo[b][1]benzoxepin-5-ol Chemical compound OC1(CC2=C(OC3=C1C=CC=C3)C=CC=C2)C2CCN(CC2)C LHPPMPJEXNAURE-UHFFFAOYSA-N 0.000 abstract 1
- LKPBEWOKJQBOAA-UHFFFAOYSA-M 5-(1-methylpyridin-1-ium-4-yl)-6H-benzo[b][1]benzoxepin-5-ol bromide Chemical compound [Br-].OC1(CC2=C(OC3=C1C=CC=C3)C=CC=C2)C2=CC=[N+](C=C2)C LKPBEWOKJQBOAA-UHFFFAOYSA-M 0.000 abstract 1
- ZBRXPLBEHGXQHG-UHFFFAOYSA-N 5-pyridin-4-yl-6H-benzo[b][1]benzoxepin-5-ol Chemical compound OC1(CC2=C(OC3=C1C=CC=C3)C=CC=C2)C2=CC=NC=C2 ZBRXPLBEHGXQHG-UHFFFAOYSA-N 0.000 abstract 1
- GAOAIAMGBAXBAP-UHFFFAOYSA-M [Br-].C1=CC=CC=2OC3=C(C(=CC21)C2=CC=[N+](C=C2)C)C=CC=C3 Chemical compound [Br-].C1=CC=CC=2OC3=C(C(=CC21)C2=CC=[N+](C=C2)C)C=CC=C3 GAOAIAMGBAXBAP-UHFFFAOYSA-M 0.000 abstract 1
- QBZFOHHUSXPAMR-UHFFFAOYSA-M [Br-].ClC1=CC2=C(OC3=C(CC2(O)C2=CC=[N+](C=C2)C)C=CC=C3)C=C1 Chemical compound [Br-].ClC1=CC2=C(OC3=C(CC2(O)C2=CC=[N+](C=C2)C)C=CC=C3)C=C1 QBZFOHHUSXPAMR-UHFFFAOYSA-M 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000000033 alkoxyamino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000794 anti-serotonin Effects 0.000 abstract 1
- 239000003420 antiserotonin agent Substances 0.000 abstract 1
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR118110A FR1559622A (de) | 1967-08-17 | 1967-08-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1184027A true GB1184027A (en) | 1970-03-11 |
Family
ID=8636980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3937068A Expired GB1184027A (en) | 1967-08-17 | 1968-08-16 | New Dibenzo-Oxepine Derivatives and their preparation |
Country Status (6)
| Country | Link |
|---|---|
| AT (4) | AT281843B (de) |
| BE (1) | BE719603A (de) |
| DE (1) | DE1795148A1 (de) |
| FR (2) | FR1559622A (de) |
| GB (1) | GB1184027A (de) |
| NL (1) | NL6811458A (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4198418A (en) * | 1979-01-10 | 1980-04-15 | American Hoechst Corporation | Spiro[dibenz(b,f)oxepin-piperidine]s |
-
1967
- 1967-08-17 FR FR118110A patent/FR1559622A/fr not_active Expired
- 1967-11-14 FR FR128140A patent/FR6829M/fr not_active Expired
-
1968
- 1968-08-12 NL NL6811458A patent/NL6811458A/xx unknown
- 1968-08-16 AT AT677369A patent/AT281843B/de active
- 1968-08-16 BE BE719603D patent/BE719603A/xx unknown
- 1968-08-16 DE DE19681795148 patent/DE1795148A1/de active Pending
- 1968-08-16 AT AT677569A patent/AT281844B/de active
- 1968-08-16 AT AT677468A patent/AT284854B/de not_active IP Right Cessation
- 1968-08-16 AT AT801868A patent/AT281834B/de not_active IP Right Cessation
- 1968-08-16 GB GB3937068A patent/GB1184027A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6811458A (de) | 1969-02-19 |
| BE719603A (de) | 1969-02-17 |
| AT281843B (de) | 1970-06-10 |
| AT281834B (de) | 1970-06-10 |
| FR6829M (de) | 1969-03-31 |
| AT284854B (de) | 1970-10-12 |
| DE1795148A1 (de) | 1971-12-30 |
| FR1559622A (de) | 1969-03-14 |
| AT281844B (de) | 1970-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |