GB1181003A - Therapeutic Compositions - Google Patents
Therapeutic CompositionsInfo
- Publication number
- GB1181003A GB1181003A GB03049/67A GB1304967A GB1181003A GB 1181003 A GB1181003 A GB 1181003A GB 03049/67 A GB03049/67 A GB 03049/67A GB 1304967 A GB1304967 A GB 1304967A GB 1181003 A GB1181003 A GB 1181003A
- Authority
- GB
- United Kingdom
- Prior art keywords
- resin
- sieve
- polystyrene
- equililination
- divinylbenzene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title 1
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 abstract 2
- 239000004793 Polystyrene Substances 0.000 abstract 2
- 229920002223 polystyrene Polymers 0.000 abstract 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical group [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 1
- 108010007979 Glycocholic Acid Proteins 0.000 abstract 1
- 229920000084 Gum arabic Polymers 0.000 abstract 1
- RFDAIACWWDREDC-UHFFFAOYSA-N Na salt-Glycocholic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(=O)NCC(O)=O)C)C1(C)C(O)C2 RFDAIACWWDREDC-UHFFFAOYSA-N 0.000 abstract 1
- 235000010489 acacia gum Nutrition 0.000 abstract 1
- 239000000205 acacia gum Substances 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 239000000783 alginic acid Substances 0.000 abstract 1
- 229960001126 alginic acid Drugs 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- -1 alginic acid salt Chemical class 0.000 abstract 1
- 239000003957 anion exchange resin Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000019634 flavors Nutrition 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- RFDAIACWWDREDC-FRVQLJSFSA-N glycocholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 RFDAIACWWDREDC-FRVQLJSFSA-N 0.000 abstract 1
- 229940099347 glycocholic acid Drugs 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L25/00—Compositions of, homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Compositions of derivatives of such polymers
- C08L25/02—Homopolymers or copolymers of hydrocarbons
- C08L25/04—Homopolymers or copolymers of styrene
- C08L25/06—Polystyrene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L93/00—Compositions of natural resins; Compositions of derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
Abstract
1,181,003. Medicines containing ion-exchange resins. MEAD JOHNSON & CO. 20 March, 1967, No. 13049/67. Heading A5B. [Also in Division C3] A therapeutically useful composition comprises a major amount by wt. of a non-toxic strongly basic polystyrene anion exchange resin e.g. a quaternary ammonium chloride substituted polystyrene, cross-linked with not more than 10% by wt. of divinylbenzene and a minor amount of acacia gum, the resin having a molecular weight of >3,000, water content of at least 65% by wt. after equililination with air at 100% relative humidity, the ability to absorb glycocholic acid from aq. solutions thereof, and a particle size such that at least 90% by wt. thereof passes a 200 mesh sieve (U.S. Sieve Standard). The composition may also contain a food flavour, alginic acid salt or ester.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB03049/67A GB1181003A (en) | 1967-03-20 | 1967-03-20 | Therapeutic Compositions |
| FR102712A FR6888M (en) | 1967-03-20 | 1967-04-14 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB03049/67A GB1181003A (en) | 1967-03-20 | 1967-03-20 | Therapeutic Compositions |
| FR102712A FR6888M (en) | 1967-03-20 | 1967-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1181003A true GB1181003A (en) | 1970-02-11 |
Family
ID=26175591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB03049/67A Expired GB1181003A (en) | 1967-03-20 | 1967-03-20 | Therapeutic Compositions |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR6888M (en) |
| GB (1) | GB1181003A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4252790A (en) * | 1974-10-23 | 1981-02-24 | Interx Research Corporation | Method for treating gastric ulcer-prone patients |
| US4747881A (en) * | 1985-02-05 | 1988-05-31 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4790991A (en) * | 1985-02-05 | 1988-12-13 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4818539A (en) * | 1985-02-05 | 1989-04-04 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4843098A (en) * | 1985-02-05 | 1989-06-27 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4851392A (en) * | 1985-02-05 | 1989-07-25 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4895723A (en) * | 1986-09-08 | 1990-01-23 | Amer And Company | Cholestyramine compositions and method for preparation thereof |
| WO1999011676A1 (en) * | 1997-08-29 | 1999-03-11 | Smithkline Beecham Plc | Formulation |
| EP1924246B1 (en) | 2005-09-15 | 2015-10-21 | Genzyme Corporation | Sachet formulation for amine polymers |
| US10245284B2 (en) | 2015-08-19 | 2019-04-02 | Alpex Pharma S.A. | Granular composition for oral administration |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3869590D1 (en) * | 1987-12-29 | 1992-04-30 | Procter & Gamble | MIXTURE FOR TREATING HYPERCHOLESTEROLEMY. |
| US5910317A (en) * | 1988-01-11 | 1999-06-08 | The Procter & Gamble Company | Mixed compositions for treating hypercholesterolemia |
| CA2098199C (en) * | 1990-12-20 | 1997-06-03 | Nabil George Kardouche | Psyllium and cholestyramine compositions with improved palatability |
| AU3812893A (en) * | 1992-03-20 | 1993-10-21 | Procter & Gamble Company, The | Anion exchange resin compositions |
| US5942550A (en) * | 1996-01-25 | 1999-08-24 | The Procter & Gamble Company | Cholesterol lowering drink mix compositions |
-
1967
- 1967-03-20 GB GB03049/67A patent/GB1181003A/en not_active Expired
- 1967-04-14 FR FR102712A patent/FR6888M/fr not_active Expired
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4252790A (en) * | 1974-10-23 | 1981-02-24 | Interx Research Corporation | Method for treating gastric ulcer-prone patients |
| US4747881A (en) * | 1985-02-05 | 1988-05-31 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4790991A (en) * | 1985-02-05 | 1988-12-13 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4818539A (en) * | 1985-02-05 | 1989-04-04 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4843098A (en) * | 1985-02-05 | 1989-06-27 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4851392A (en) * | 1985-02-05 | 1989-07-25 | Warner-Lambert Company | Ingestible aggregate and delivery system prepared therefrom |
| US4895723A (en) * | 1986-09-08 | 1990-01-23 | Amer And Company | Cholestyramine compositions and method for preparation thereof |
| WO1999011676A1 (en) * | 1997-08-29 | 1999-03-11 | Smithkline Beecham Plc | Formulation |
| EP1924246B1 (en) | 2005-09-15 | 2015-10-21 | Genzyme Corporation | Sachet formulation for amine polymers |
| US10245284B2 (en) | 2015-08-19 | 2019-04-02 | Alpex Pharma S.A. | Granular composition for oral administration |
| US10688121B2 (en) | 2015-08-19 | 2020-06-23 | Alpex Pharma S.A. | Granular composition for oral administration |
Also Published As
| Publication number | Publication date |
|---|---|
| FR6888M (en) | 1969-04-21 |
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