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GB1019162A - Process for the preparation of phospholipid antithromboplastins - Google Patents

Process for the preparation of phospholipid antithromboplastins

Info

Publication number
GB1019162A
GB1019162A GB2373/63A GB237363A GB1019162A GB 1019162 A GB1019162 A GB 1019162A GB 2373/63 A GB2373/63 A GB 2373/63A GB 237363 A GB237363 A GB 237363A GB 1019162 A GB1019162 A GB 1019162A
Authority
GB
United Kingdom
Prior art keywords
phospholipid
antithromboplastins
preparation
temperature
alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2373/63A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Armour Pharmaceutical Co
Original Assignee
Armour Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Armour Pharmaceutical Co filed Critical Armour Pharmaceutical Co
Publication of GB1019162A publication Critical patent/GB1019162A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Phospholipid antithromboplastins are produced by heating the alcohol insoluble portion of a phospholipid which has previously been separated from the alcohol soluble portion at a temperature of 40 DEG to 90 DEG C. which is below the decomposition temperature of the material, for between 1 and 21 days until the material acquires antithromboplastic activity. The phospholipid may be obtained from liver, kidney, brain, soybean or corn.
GB2373/63A 1962-01-19 1963-01-18 Process for the preparation of phospholipid antithromboplastins Expired GB1019162A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16743762A 1962-01-19 1962-01-19

Publications (1)

Publication Number Publication Date
GB1019162A true GB1019162A (en) 1966-02-02

Family

ID=22607377

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2373/63A Expired GB1019162A (en) 1962-01-19 1963-01-18 Process for the preparation of phospholipid antithromboplastins

Country Status (4)

Country Link
DE (1) DE1174940B (en)
ES (1) ES283985A1 (en)
FR (1) FR1514910A (en)
GB (1) GB1019162A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130012473A1 (en) * 2010-03-17 2013-01-10 Ktb Tumorforschungsgesellschaft Mbh Combined use of phospholipid and sulfate groups-carrying polysaccharides for inhibiting metastatic spread

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130012473A1 (en) * 2010-03-17 2013-01-10 Ktb Tumorforschungsgesellschaft Mbh Combined use of phospholipid and sulfate groups-carrying polysaccharides for inhibiting metastatic spread

Also Published As

Publication number Publication date
ES283985A1 (en) 1963-03-16
FR1514910A (en) 1968-03-01
DE1174940B (en) 1964-07-30

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