GB1014350A - 1-phenyl-n-amyl mono-ester of camphoric acid, and a process for the preparation thereof - Google Patents
1-phenyl-n-amyl mono-ester of camphoric acid, and a process for the preparation thereofInfo
- Publication number
- GB1014350A GB1014350A GB1533964A GB1533964A GB1014350A GB 1014350 A GB1014350 A GB 1014350A GB 1533964 A GB1533964 A GB 1533964A GB 1533964 A GB1533964 A GB 1533964A GB 1014350 A GB1014350 A GB 1014350A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amyl
- phenyl
- ester
- mono
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LSPHULWDVZXLIL-UHFFFAOYSA-N Camphoric acid Natural products CC1(C)C(C(O)=O)CCC1(C)C(O)=O LSPHULWDVZXLIL-UHFFFAOYSA-N 0.000 title abstract 2
- LSPHULWDVZXLIL-QUBYGPBYSA-N camphoric acid Chemical compound CC1(C)[C@H](C(O)=O)CC[C@]1(C)C(O)=O LSPHULWDVZXLIL-QUBYGPBYSA-N 0.000 title abstract 2
- VFZDNKRDYPTSTP-UHFFFAOYSA-N 5,8,8-trimethyl-3-oxabicyclo[3.2.1]octane-2,4-dione Chemical compound O=C1OC(=O)C2(C)CCC1C2(C)C VFZDNKRDYPTSTP-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention comprises the 1-phenyl-n-amyl monoester of camphoric acid of formula <FORM:1014350/C2/1> and non-toxic salts thereof. The ester may be prepared by reacting camphoric anhydride and sodium 1-phenylamylate in an inert organic solvent at 30-150 DEG C. The above compounds have cholepoietic activity and may be administered intramuscularly or intravenously, or orally as tablets, pills, capsules, syrups or elixirs.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT151564 | 1964-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1014350A true GB1014350A (en) | 1965-12-22 |
Family
ID=11101694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1533964A Expired GB1014350A (en) | 1964-01-23 | 1964-04-14 | 1-phenyl-n-amyl mono-ester of camphoric acid, and a process for the preparation thereof |
Country Status (3)
| Country | Link |
|---|---|
| CH (1) | CH425773A (en) |
| FR (2) | FR1605504A (en) |
| GB (1) | GB1014350A (en) |
-
1964
- 1964-04-14 GB GB1533964A patent/GB1014350A/en not_active Expired
- 1964-04-21 CH CH516264A patent/CH425773A/en unknown
- 1964-08-12 FR FR985032A patent/FR1605504A/en not_active Expired
- 1964-11-10 FR FR994512A patent/FR4089M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH425773A (en) | 1966-12-15 |
| FR1605504A (en) | 1978-02-24 |
| FR4089M (en) | 1966-04-18 |
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