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GB1079989A - Carbocyclic propanolamines - Google Patents

Carbocyclic propanolamines

Info

Publication number
GB1079989A
GB1079989A GB4120365A GB4120365A GB1079989A GB 1079989 A GB1079989 A GB 1079989A GB 4120365 A GB4120365 A GB 4120365A GB 4120365 A GB4120365 A GB 4120365A GB 1079989 A GB1079989 A GB 1079989A
Authority
GB
United Kingdom
Prior art keywords
stands
ester
salt
treatment
propanolamines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4120365A
Inventor
Bernard Joseph Mcloughlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB4120365A priority Critical patent/GB1079989A/en
Publication of GB1079989A publication Critical patent/GB1079989A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/36—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a (4.4.0) system, e.g. naphols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Racemic compounds of the general formula <FORM:1079989/C2/1> (wherein R3 stands for a C3- 5 cycloalkyl radica and n stands for 1 or 2), their carboxylic esters and acid addition salts of the alcohols and esters are prepared by reacting a compound of the formula <FORM:1079989/C2/2> (wherein A stands for the group <FORM:1079989/C2/3> or -CHOH.CH2X, wherein X stands for a halogen atom) with R3NH2, optionally followed by conversion to a salt, ester or salt of an ester. The compounds of the invention are useful in the treatment or prophylaxis of heart diseases and in the treatment of hypertension and phaeochromocytoma, and may be administered in the form of pharmaceutical preparations containing them together with a diluent or carrier.
GB4120365A 1965-09-28 1965-09-28 Carbocyclic propanolamines Expired GB1079989A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB4120365A GB1079989A (en) 1965-09-28 1965-09-28 Carbocyclic propanolamines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4120365A GB1079989A (en) 1965-09-28 1965-09-28 Carbocyclic propanolamines

Publications (1)

Publication Number Publication Date
GB1079989A true GB1079989A (en) 1967-08-16

Family

ID=10418595

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4120365A Expired GB1079989A (en) 1965-09-28 1965-09-28 Carbocyclic propanolamines

Country Status (1)

Country Link
GB (1) GB1079989A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953456A (en) * 1972-12-14 1976-04-27 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and process for preparing the same
US5420294A (en) * 1988-06-03 1995-05-30 Eli Lilly And Company Cycloalkylaminoalkoxyindoles

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953456A (en) * 1972-12-14 1976-04-27 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and process for preparing the same
US5420294A (en) * 1988-06-03 1995-05-30 Eli Lilly And Company Cycloalkylaminoalkoxyindoles
US5554640A (en) * 1988-06-03 1996-09-10 Eli Lilly And Company Use of propanolamine derivatives as selective 5-HT1 antagonists

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